Gene CG3290 in Drosophila melanogaster

Synonym: Dmel\CG3290, Dmel_CG3290, CG3290

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold AP
Superfamily AP
Family AP
Subfamily AP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP007_AA protein Get Run
DmelP007_AA_56-529 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_AP_pd Subfamily AP 62-528 1.6e-195 640.9 In-house 2-470 (472) alignment 
Range on Protein: 62-528
Range on HMM: 2-470/472.0
DPQFWYKLADEEIAKRLQLPqPNSDRAKNVIMFLGDGMPISTVTAARILKGQRQGNTGEESSLSFEKFPYSGLSRTYCANAQVPDSACTATAYLCGVKTN
...||.|.|.||....|.|. .||..|||||.|||||| .||||||||||||..|..|||.||..|.||| |||.||....||||||.||||||||||||
sakfwlkkaqeelkealelq.snskkakNvilflgdGmgvstvtaaRilkgqlkgelgeeasLaleeFpyvglsktyssdkqvpdsaatAtAylcGvktn

IINIGVSAAVNFNNCTASQdpANRLTSIAEWAQNAGKSTGFVTTTTLTHASPSGAYAKTANRMWQSDTDVTSYGVdASTCVDMATQLVTQTPGKNFEVMF
  .|||.|||....|.||.  .....||.|.|..|||.||.||||..|||||.|.||..|||.|.||..|....  ...|.|.|.||.....||...|..
ngtiGvdaaverkdCeasa..gkevdsileaAkkaGkatGlVtttrvthAsPaglyahvanRnwesdeevpaeae.kegckdiaqQLieeevgkeldvil

GGGMGKFLPKTTKDSHGKY-GERSDGVNLLSRWQGLHDKGVLVTNRKQLLNLDVSAASSIIGTFQSGLMDFHMDADPTYQPTLSELTEVAIKKLSHNENG
|||. ||||||.|||...  |||.|| ||...|.  ... ..|.|||.|.|.|.|......| |... .....|.|.. .|.|.|.||.|.. ||.||||
GGGrkkflpktvkdseyekkgerkDgrnLieewekekknakyvenrkelenvdksktdrllGlfadshlkyeidrdekeePsLkemtekAlevLsknenG

YFVFIEGGLIDYGNHYTQAGYALDEALEFEKAIQLAREMTNISDTLIVVTADHGHAVSIAGYPGRGTPILGLNQHDTDINGVKYSVLNYAAGPNQYLDEH
.|.|.|||.||...| ..| .||.|.|||..|..||.|.|. .||||||||||.|...||||| ||..||||...... ....|..|.|| ||...|.|.
ffLfVEggrIDhahhenkakkaleetlefdeavelaleltdeedTlivvtaDHshtltiagypkrgssilglakesksadelpyttlsyangpgyeltes

----GQRIPLDDIL-GPDDAISPSYIDKEIGVHSGEDVGIWASGPQSHLFTGVMQQSTIPHLMAYASCVGSGK
    |.|  |...  . .|..|..... | ..|.||||...||||||||.|||..||||.|.||||.|.|...
dleegerkdlteaeteakdyvsqaavpleeetHggeDvavyasGpqshlltGvveqstiahvmayaaclgeae
0037220 Alkaline phosphatase-like 57-529 9.1e-147 479.7 In-house 3-473 (479) alignment 
Range on Protein: 57-529
Range on HMM: 3-473/479.0
PPEEMDPQFWYKLADEEIAKRLqLPQPNSDRAKNVIMFLGDGMPISTVTAARILKGQRQGNTGEESSLSFEKFPYSGLSRTYCANAQVPDSACTATAYLC
. ......... || . ..  | |...|...|||||.|.|||| .||||||||..|| .|..|||. |...|||..||..||.....|.|||..|||...
lllllllllllllalallllal.llllnkskaknvilfigDGmgvstvtaariylgqllgglgeegllaldkfplvglvkTysvdslvtDSAaaaTAlat

GVKTNIINIGVSAAVNFNNCTASQDpaNRLTSIAEWAQNAGKSTGFVTTTTLTHASPSGAYAKTANRMWQSDTDVTSYGVDAStCVDMATQLVtqtPGKN
|||||.  |||.|.| ..||... .  |....|.|.|. |||.||.||||..|||.|.. ||..||| |..|...  .|..|. | |.|||||   .|..
GvKtnngaigvdadvsrdncddplg..npvetilelakeaGkatGlVtTtrithATPAafyAhvanRnweddialqllgleag.ckdiatqlv...lgsg

FEVMFGGGMGKFLPKTTKDSHGK-----YGERSDGVNLLSRWQGLHDKGVLVTNRKQLLNLDV-SAASSIIGTFQSGLMDFHMDADPTYQPTLSELTEVA
..|..|||.  ||||.|.| ...      | |.|| .||. ..  ...  .||||..|..||. |. . ..| |... .....| |.. .|.|.|.||.|
ldvilGGGrkyflpkgtldpeydlelllggkrldgrdlleeakekkkgytyvtnreeldaldlgsnvdkllGlfadshlpyeldrdaseePsLaemtekA

IKKLSHNENGYFVFIEGGLIDYGNHYTQAGYALDEALEFEKAIQLAREMTNISDTLIVVTADHGHAVSIAGYPGRGTPILGLNQHDtDINGVKYSVLNYA
.. || |..|.|...||| ||...| . | .||.|.|.|..|...|.|... .|||.||||||.|...| ||..||.||||| ..  ...|..|. | ||
ldlLskndkGFfLmvEggriDhagHandaaaalgevlafdeaveaalefakdddTlvvvtADHshgglilgyadrgnpilgllpgl.lldglpyttllya

AGPNQYLDEHGQRIPLDDILGPDDAISPSYIDKEIGVHSGEDVGIWASGPQSHLFTGVMQQSTIPHLMAYASCVGSGKQ
 ||. .|  .   ..   ..   . . ..... . | |.|||| ..|.||...||.||.... |.|..|.| ..|  . 
ngpgflllldlrldltllvtlallllqralvgwtsggHtgedVpvyayGpgaelflgvyentdiahviasalglgllev
Alk_phosphatase Alkaline phosphatase 88-523 2.2e-122 399.6 Pfam-A 1-420 (421) alignment 
Range on Protein: 88-523
Range on HMM: 1-420/421.0
AKNVIMFLGDGMPISTVTAARILKGQRQGNTGEESsLSFEKFPYSGLSRTYCANAQVPDSACTATAYLCGVKTNIINIGVSaavnfnnctasqDPANRLT
|||||...||||  |||||||.||.|..|..|||  | ....|..|||.||. ..||.|||.|||||.|||||.   |||.            .  .. .
aknvilligDGmgvstvtaaRslkeqakgklgeei.laldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvd............thgkevk

SIAEWAQNAGKSTGFVTTTTLTHASPSGAYAKTANRMWQSDTDVtSYGVDASTCVDMATQLVTQTpgKNFEVMFGGGMGKFLPKTTKDSHGKYGERSDGV
|. |.|..|||||| |||| .|||.|.. .|..|.| |..|... .       . |.|.||. ..  |...|..|||  .|||..|||.... | | || 
svleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaat.aasakkeGkkdiaeqlikak..kkidvllGGGrkeflptgtkdeekerGtrldgr

NLLSRWqgLHDKGVLVTNRKQLLNLDVSA-ASSIIGTFQSGLMDFHMDADPTYQPTLSELTEVAIKKLSHNENGYFVFIEGGLIDYGNHYTQAGYALDEA
||  ..   .    .|..||.||.   .   . ..| |. | . .... |.. .|.|.|.||||||.||.||.|.| ..||. || ..| ..|  ||.|.
nlieea..kkagyqyvsdrkeLlkakeensvkplLGLFadgdlkvelerdekeePsLkemtevAiklLsknekGFFLlVEGsrIDhaaHendavgalsEv

LEFEKAIQLAREMT-NISDTLIVVTADHGHAVSIAGYPGRGTPILGLNQHDTDINGVKYSVLNYAAGPNQYLDE-HGQRIPLDDILgPDDAISPSYIDKE
.||..|.. | |.. . ..||.|||||| |..||.||. ||| | || .  .. .| .. ...|. |. . ...   . .  .. |  .     | .  .
vefdeAvkaalefakkeketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygngegakvedgarenvtaeeal.ekiyrkrsavglt

IGVHSGEDVGIWASGPQSHLFTGVMQQSTIPHLMAYASC
   |.|||| ..| ||...|..||..| .|.. .|.| .
seeHtgedvavfAygpkaelvrGvqeqteiakvlaaale
Alk_phosphatase Alkaline phosphatase 88-523 2.2e-122 399.6 In-house 1-420 (421) alignment 
Range on Protein: 88-523
Range on HMM: 1-420/421.0
AKNVIMFLGDGMPISTVTAARILKGQRQGNTGEESsLSFEKFPYSGLSRTYCANAQVPDSACTATAYLCGVKTNIINIGVSaavnfnnctasqDPANRLT
|||||...||||  |||||||.||.|..|..|||  | ....|..|||.||. ..||.|||.|||||.|||||.   |||.            .  .. .
aknvilligDGmgvstvtaaRslkeqakgklgeei.laldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvd............thgkevk

SIAEWAQNAGKSTGFVTTTTLTHASPSGAYAKTANRMWQSDTDVtSYGVDASTCVDMATQLVTQTpgKNFEVMFGGGMGKFLPKTTKDSHGKYGERSDGV
|. |.|..|||||| |||| .|||.|.. .|..|.| |..|... .       . |.|.||. ..  |...|..|||  .|||..|||.... | | || 
svleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaat.aasakkeGkkdiaeqlikak..kkidvllGGGrkeflptgtkdeekerGtrldgr

NLLSRWqgLHDKGVLVTNRKQLLNLDVSA-ASSIIGTFQSGLMDFHMDADPTYQPTLSELTEVAIKKLSHNENGYFVFIEGGLIDYGNHYTQAGYALDEA
||  ..   .    .|..||.||.   .   . ..| |. | . .... |.. .|.|.|.||||||.||.||.|.| ..||. || ..| ..|  ||.|.
nlieea..kkagyqyvsdrkeLlkakeensvkplLGLFadgdlkvelerdekeePsLkemtevAiklLsknekGFFLlVEGsrIDhaaHendavgalsEv

LEFEKAIQLAREMT-NISDTLIVVTADHGHAVSIAGYPGRGTPILGLNQHDTDINGVKYSVLNYAAGPNQYLDE-HGQRIPLDDILgPDDAISPSYIDKE
.||..|.. | |.. . ..||.|||||| |..||.||. ||| | || .  .. .| .. ...|. |. . ...   . .  .. |  .     | .  .
vefdeAvkaalefakkeketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygngegakvedgarenvtaeeal.ekiyrkrsavglt

IGVHSGEDVGIWASGPQSHLFTGVMQQSTIPHLMAYASC
   |.|||| ..| ||...|..||..| .|.. .|.| .
seeHtgedvavfAygpkaelvrGvqeqteiakvlaaale
Sulfatase Sulfatase 175-431 3.2e-06 16.1 Pfam-A 75-266 (308) alignment 
Range on Protein: 175-431
Range on HMM: 75-266/308.0
NctasQDPANRLTSIAEWAQNAGKSTGFVTTTTLTHASPSG---------AYA--KTANRMWQSD-TDVT-------SYGVDASTCVDMATQLVTQTPGK
.    . .... ....|. ..||  |...  ..|.. | ..          ..  .. .......  ...       ..|..    .| | ... ....|
e....gglpqteatLpellkeaGYntaaigkwhlgwssrqsvyknrgfdrflgfptgeaalknpekveyngevlrppeggysddrlldealefllarndk

NFEVMFGGGMGKFLPKTTKDSHGKYGERSDGVNLLSRwqglhdkgvlvtnrkqllnldvsaassiigtfqsglmdfhmdadptyqptlseltevaikkls
.| ...      . |  ... ..|| ...|  .  .|                                                               
pfflylatlapHappeapdeyaekyatffddgeeaar...............................................................

hnengyfvfieggliDYGNHYTQAGYALDEALefEKAIQLAREMTNISDTLIVVTADHGHAVSIAGYPGRGTPILG
                . . | .. .  |...  .. .. ..|     .||.|.|.|||...  ...| ||..   
...............qlleaylnsveyvDdli..grvlaaLeenglldntlvvftSDhgasleesngplrggkgan