Gene CG5150 in Drosophila melanogaster

Synonym: Dmel\CG5150, Dmel_CG5150, CG5150

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold AP
Superfamily AP
Family AP
Subfamily AP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP009_AA protein Get Run
DmelP009_AA_47-510 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_AP_pd Subfamily AP 50-511 4.1e-190 623.1 In-house 2-468 (472) alignment 
Range on Protein: 50-511
Range on HMM: 2-468/472.0
TQEFWHSASKKLIREKLEFVRNTKKAKNIILFLGDGMGLATLAAARSYIG------GEELKLSFEEFPFTGLSKTYSVDKIVPDSACTSTSYLCGVKANY
...||.. ... ..|.||  .|.|||||.|||||||||..|..|||.. |      ||| .|..||||..|||||||.||.|||||.|.|.||||||.|.
sakfwlkkaqeelkealelqsnskkakNvilflgdGmgvstvtaaRilkgqlkgelgeeasLaleeFpyvglsktyssdkqvpdsaatAtAylcGvktnn

GTIGVNAHVKRGDCAAMAneTNHVFSLGKWAMDAGKAAGLVTTTRVTHASPSGVYAHVADREWENNAVLEEACGelSDGLQDIAVQLIHGEVGSKLKVML
|||||.|.|.|.||.|.|  ...| |. ..|..||||.|||||||||||||.|.|||||.|.||... ... .   ..| .||| |||. |||..|.|.|
gtiGvdaaverkdCeasa..gkevdsileaAkkaGkatGlVtttrvthAsPaglyahvanRnwesdeevpaeae..kegckdiaqQLieeevgkeldvil

GGGKRSFYSPEHYDK-----GRRTDGRNLVEEFEALDAGNTFVKTQKKLLNVNATETGRLLGLFSKSHMHYHLEQladPDNNEPTLEEMTQKAIEVLETE
|||...|.. .. |.     |.|.|||||.||.|. ......|...|.|.||....|.||||||..||..|....    ...||.|.|||.||.|||. .
GGGrkkflpktvkdseyekkgerkDgrnLieewekekknakyvenrkelenvdksktdrllGlfadshlkyeidr...dekeePsLkemtekAlevLskn

EQGYFLFVEGGKIDISHHETMARIALDETAELSKAVKKAREMTNPEETLIVVTSDHSHTFSVSGYQPRGSDIFGAAK-ANGKDGKPYLALSYANGKSFQD
|.|.|||||||.||..|||..|. ||.||.|...||..|.|.|..|.||||||.|||||....||. |||.|.| ||  . .|..||..||||||.....
enGffLfVEggrIDhahhenkakkaleetlefdeavelaleltdeedTlivvtaDHshtltiagypkrgssilglakesksadelpyttlsyangpgyel

YYN-TETHERVDPTSLPTiGDFDQLFPAMVPLESETHGGEDVGVFASGPWAHLFTGVYEQNTIPHMMAFAACVGD
 .. .|..|| |.|.. | .. | ...|.||||.||||||||.|.||||..||.|||.||.||.|.||.|||.|.
tesdleegerkdlteaet.eakdyvsqaavpleeetHggeDvavyasGpqshlltGvveqstiahvmayaaclge
0037220 Alkaline phosphatase-like 48-510 1.5e-147 482.3 In-house 6-469 (479) alignment 
Range on Protein: 48-510
Range on HMM: 6-469/479.0
EETQEFWHSASKKLIREKLEFVRNTKKAKNIILFLGDGMGLATLAAARSYIG------GEELKLSFEEFPFTGLSKTYSVDKIVPDSACTSTSYLCGVKA
.... ...     |. . | .. |..||||.|||.|||||..|..||| | |      ||| .|....||..||.||||||..|.|||...|....|||.
llllllllllalallllalllllnkskaknvilfigDGmgvstvtaariylgqllgglgeegllaldkfplvglvkTysvdslvtDSAaaaTAlatGvKt

NYGTIGVNAHVKRGDCAAMANetNHVFSLGKWAMDAGKAAGLVTTTRVTHASPSGVYAHVADREWENNAVLEEACGELSdgLQDIAVQLIhgeVGSKLKV
|.|.|||.|.|.|..| .. .  |.| .. ..| .|||| |||||||.|||.|...|||||.| ||... |.    | .  ..||| ||.   .||.|.|
nngaigvdadvsrdncddplg..npvetilelakeaGkatGlVtTtrithATPAafyAhvanRnweddialqllgleag..ckdiatqlv...lgsgldv

MLGGGKRSFYSPEH---------YDKGRRTDGRNLVEEFEALDAGNTFVKTQKKLLNVNA-TETGRLLGLFSKSHMHYHLEQladPDNNEPTLEEMTQKA
.|||| . |.. .          . .|.|.|||.|.||... ..| |.| . ..|..... .....|||||..||..|.|.    . ..||.|.|||.||
ilGGGrkyflpkgtldpeydlelllggkrldgrdlleeakekkkgytyvtnreeldaldlgsnvdkllGlfadshlpyeldr...daseePsLaemtekA

IEVLETEEQGYFLFVEGGKIDISHHETMARIALDETAELSKAVKKAREMTNPEETLIVVTSDHSHTFSVSGYQPRGSDIFGAAKANGKDGKPYLALSYAN
...|.. ..|.||.||||.||. .|.. |. ||.|. ....||. |.|......||.|||.||||.... ||. ||..|.| ..    ||.||..|.|||
ldlLskndkGFfLmvEggriDhagHandaaaalgevlafdeaveaalefakdddTlvvvtADHshgglilgyadrgnpilgllpgllldglpyttllyan

GKSFQDYYNTetheR--VdptSLPTIGDFDQLFPAMVPLESETHGGEDVGVFASGPWAHLFTGVYEQNTIPHMMAFAACVG
|..|  ....    |  .   .| .. ... |..|.|...|..|.|||| |.|.||.|.||.||||.. |.|..|.|...|
gpgflllldl....rldl...tllvtlallllqralvgwtsggHtgedVpvyayGpgaelflgvyentdiahviasalglg
Alk_phosphatase Alkaline phosphatase 75-509 1.7e-127 416.3 Pfam-A 1-421 (421) alignment 
Range on Protein: 75-509
Range on HMM: 1-421/421.0
AKNIILFLGDGMGLATLAAARSYIGGEELK-----LSFEEFPFTGLSKTYSVDKIVPDSACTSTSYLCGVKANYGTIGVNahvkrgdcaamaNETNHVFS
|||.||..||||| .|..||||. .... |     | ....|..||||||.||| |.|||.|.| |.||||.. |.|||.            .....| |
aknvilligDGmgvstvtaaRslkeqakgklgeeilaldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvd............thgkevks

LGKWAMDAGKAAGLVTTTRVTHASPSGVYAHVADREWENNAVLeeACGELSDGLQDIAVQLIHGEvgSKLKVMLGGGKRSFYSPEHYD----KGRRTDGR
. ..| .|||. |||||||||||.|....||||.|.||..|    |    ..| .||| |||. .   |..|.||||.. |.   . |    .| |.|||
vleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaat..aasakkeGkkdiaeqlikak..kkidvllGGGrkeflptgtkdeekerGtrldgr

NLVEEFeaLDAGNTFVKTQKKLLNVNATE-TGRLLGLFSKSHMHYHLeqlADPDNNEPTLEEMTQKAIEVLETEEQGYFLFVEGGKIDISHHETMARIAL
||.||.    ||  .|...|.||...  . .  |||||  ......|    . ...||.|.|||..||..|. .|.|.||.|||..||  .||. |  ||
nlieea..kkagyqyvsdrkeLlkakeensvkplLGLFadgdlkvel...erdekeePsLkemtevAiklLsknekGFFLlVEGsrIDhaaHendavgal

DETAELSKAVKKAREMT-NPEETLIVVTSDHSHTFSVSGYQPRGSDIFGAAKANG-KDGKPYLALSYANGKSfqdyYNTETHERVDPTSlPTIGDFDQLF
.|. |. .|||.| |.. . .|||.|||.||||.||..||..||..|.| |.|.  ||||.. ...|.||..    .. | ..| . |     ..    .
sEvvefdeAvkaalefakkeketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygngeg....akvedgarenvta.eealekiyrk

PAMVPLESETHGGEDVGVFASGPWAHLFTGVYEQNTIPHMMAFAACV
 . |.|.||.|.|||| ||| || |.|..||.||..|....|.|...
rsavgltseeHtgedvavfAygpkaelvrGvqeqteiakvlaaalel
Alk_phosphatase Alkaline phosphatase 75-509 1.7e-127 416.3 In-house 1-421 (421) alignment 
Range on Protein: 75-509
Range on HMM: 1-421/421.0
AKNIILFLGDGMGLATLAAARSYIGGEELK-----LSFEEFPFTGLSKTYSVDKIVPDSACTSTSYLCGVKANYGTIGVNahvkrgdcaamaNETNHVFS
|||.||..||||| .|..||||. .... |     | ....|..||||||.||| |.|||.|.| |.||||.. |.|||.            .....| |
aknvilligDGmgvstvtaaRslkeqakgklgeeilaldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvd............thgkevks

LGKWAMDAGKAAGLVTTTRVTHASPSGVYAHVADREWENNAVLeeACGELSDGLQDIAVQLIHGEvgSKLKVMLGGGKRSFYSPEHYD----KGRRTDGR
. ..| .|||. |||||||||||.|....||||.|.||..|    |    ..| .||| |||. .   |..|.||||.. |.   . |    .| |.|||
vleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaat..aasakkeGkkdiaeqlikak..kkidvllGGGrkeflptgtkdeekerGtrldgr

NLVEEFeaLDAGNTFVKTQKKLLNVNATE-TGRLLGLFSKSHMHYHLeqlADPDNNEPTLEEMTQKAIEVLETEEQGYFLFVEGGKIDISHHETMARIAL
||.||.    ||  .|...|.||...  . .  |||||  ......|    . ...||.|.|||..||..|. .|.|.||.|||..||  .||. |  ||
nlieea..kkagyqyvsdrkeLlkakeensvkplLGLFadgdlkvel...erdekeePsLkemtevAiklLsknekGFFLlVEGsrIDhaaHendavgal

DETAELSKAVKKAREMT-NPEETLIVVTSDHSHTFSVSGYQPRGSDIFGAAKANG-KDGKPYLALSYANGKSfqdyYNTETHERVDPTSlPTIGDFDQLF
.|. |. .|||.| |.. . .|||.|||.||||.||..||..||..|.| |.|.  ||||.. ...|.||..    .. | ..| . |     ..    .
sEvvefdeAvkaalefakkeketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygngeg....akvedgarenvta.eealekiyrk

PAMVPLESETHGGEDVGVFASGPWAHLFTGVYEQNTIPHMMAFAACV
 . |.|.||.|.|||| ||| || |.|..||.||..|....|.|...
rsavgltseeHtgedvavfAygpkaelvrGvqeqteiakvlaaalel