Gene CG5656 in Drosophila melanogaster

Synonym: Dmel\CG5656, Dmel_CG5656, CG5656

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold AP
Superfamily AP
Family AP
Subfamily AP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP011_AA protein Get Run
DmelP011_AA_36-522 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_AP_pd Subfamily AP 39-516 1.9e-199 653.9 In-house 2-469 (472) alignment 
Range on Protein: 39-516
Range on HMM: 2-469/472.0
SKEFWFHDAQRTLYNKLSTPPNQYRAKNVIFFLGDGMSVPTVTAGRIFDGQLRGVVGERNRLEFEKFNYVGLSKTYCVNKQVADSACTASAYLSGIKANY
|..||...||..| ..|....|. .|||||.||||||.| ||||.||..|||.| .||...|..|.|.||||||||...|||.|||.||.|||.|.|.|.
sakfwlkkaqeelkealelqsnskkakNvilflgdGmgvstvtaaRilkgqlkgelgeeasLaleeFpyvglsktyssdkqvpdsaatAtAylcGvktnn

LTIGVTADVELNDCRGSRlpQNRLSSIAAWALKGSKSAGLVTTTRVTHASPAGVYAHTSNRDFESDYDVTKLGQnPGNCPDIAQQLIDGDVGKRLRVVMG
 ||||.|.|| .||. |.  .....||...| | .|..|||||||||||||||.|||..||..||| .|.. .. . .| |||||||. .|||.|.|..|
gtiGvdaaverkdCeasa..gkevdsileaAkkaGkatGlVtttrvthAsPaglyahvanRnwesdeevpaeae.kegckdiaqQLieeevgkeldvilG

GGTIKFLPNTTNDVFGNK-GQRLDNRNLIEEWqQTKPGNARVVFSRTDLLNNDAQNTDFLLGLFNASHLAYHMD-DSIDTPTLPEMTAAAINVLSRDPNG
||. ||||.|..|  ..| |.| |.||||||| ...  ||..|..|..|.| |...|| |||||. |||.|..| |. ..|.| |||..|..|||...||
GGrkkflpktvkdseyekkgerkDgrnLieew.ekekknakyvenrkelenvdksktdrllGlfadshlkyeidrdekeePsLkemtekAlevLsknenG

YFLFVEGGRIDHAHHETKAKKALDETVQFSDAVRKARQLTNPWDTLIVVSADHGHTVTISGYPDVNNSIVGLNSELSNVDQLPYTSISYANGPAYERFYK
.|||||||||||||||.||||||.||..|..||..|..||...||||||.|||.||.||.|||. ..||.||..| .. |.|||| .||||||.||....
ffLfVEggrIDhahhenkakkaleetlefdeavelaleltdeedTlivvtaDHshtltiagypkrgssilglakesksadelpyttlsyangpgyeltes

STDGvVERVDLRNLDFSKPDAIYPHGVPMTEETHGGGDVAVYAhvveyllQGPWSHLFTGVYEQSTLPHLMGFASCLGPG
...   || ||.... ...|..... ||..|||||| ||||||       .||.|||.|||.||||..|.| .|.|||..
dlee.gerkdlteaeteakdyvsqaavpleeetHggeDvavya.......sGpqshlltGvveqstiahvmayaaclgea
0037220 Alkaline phosphatase-like 37-522 2e-146 478.6 In-house 6-477 (479) alignment 
Range on Protein: 37-522
Range on HMM: 6-477/479.0
LKSKEFWFHDAQRTLYNKLSTPPNQYRAKNVIFFLGDGMSVPTVTAGRIFDGQLRGVVGERNRLEFEKFNYVGLSKTYCVNKQVADSACTASAYLSGIKA
|..  .... |. .|.  | ...|. .|||||.|.||||.|.|||| ||. |||.|  ||...| ..||..|||.|||.|...|.|||..|.|...|.|.
llllllllllalallllalllllnkskaknvilfigDGmgvstvtaariylgqllgglgeegllaldkfplvglvkTysvdslvtDSAaaaTAlatGvKt

NYLTIGVTADVELNDCRGSRLpqNRLSSIAAWALKGSKSAGLVTTTRVTHASPAGVYAHTSNRDFESDYDVTKLGQNPGnCPDIAQQLIdgdVGKRLRVV
|. .|||.|||. ..|  ..   |.. .|. .| .  |. |||||||.|||.||..|||. ||..|.|...  ||...| |.|||.||.   .|..| |.
nngaigvdadvsrdncddplg..npvetilelakeaGkatGlVtTtrithATPAafyAhvanRnweddialqllgleag.ckdiatqlv...lgsgldvi

MGGGTIKFLPNTTNDVFGN-----KGQRLDNRNLIEEWQQTKPGnARVVFSRTDLLNNDA-QNTDFLLGLFNASHLAYHMDD-SIDTPTLPEMTAAAINV
.|||   |||..| |....     .|.|||.|.|.||... |.| ...|..|..|.. |. .|.| |||||. |||.|..|.   ..|.| ||| .|...
lGGGrkyflpkgtldpeydlelllggkrldgrdlleeakekkkg.ytyvtnreeldaldlgsnvdkllGlfadshlpyeldrdaseePsLaemtekAldl

LSRDPNGYFLFVEGGRIDHAHHETKAKKALDETVQFSDAVRKARQLTNPWDTLIVVSADHGHTVTISGYPDVNNSIVGLNSELsNVDQLPYTSISYANGP
||....|.||.|||||||||.|...|. ||.|...|..||. |...... |||.||.|||.|...| ||.| .|.|.|| ..|  .| |||| ..|||||
LskndkGFfLmvEggriDhagHandaaaalgevlafdeaveaalefakdddTlvvvtADHshgglilgyadrgnpilgllpgl.lldglpyttllyangp

AYERFYKStdgvveRVDLRNLDFSKPDAIYPHGVPMTEETHGGGDVAVYAHvveyllqGPWSHLFTGVYEQSTLPHLMGFASCLGPGITYCDL
 .  ...       |.||  |.. ... ... .|..| ..|.| ||.|||.       ||...||.||||.. ..|.. .| .||.  ....|
gflllldl......rldltllvtlallllqralvgwtsggHtgedVpvyay.......Gpgaelflgvyentdiahviasalglgllevllll
Alk_phosphatase Alkaline phosphatase 64-513 7.5e-127 414.3 Pfam-A 1-421 (421) alignment 
Range on Protein: 64-513
Range on HMM: 1-421/421.0
AKNVIFFLGDGMSVPTVTAGRIFDGQLRGVVGERNrLEFEKFNYVGLSKTYCVNKQVADSACTASAYLSGIKANYLTIGVTadvelndcrgsrLPQNRLS
|||||...||||.|.|||| |.. .| .| .||   |.......|||||||.|.|||.|||.|| ||..|.|..  .|||.              ...  
aknvilligDGmgvstvtaaRslkeqakgklgeei.laldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvd............thgkevk

SIAAWALKGSKSAGLVTTTRVTHASPAGVYAHTSNRDFESDYDVTKLGQNPGnCPDIAQQLIDGDvgKRLRVVMGGGTIKFLPNTTNDVFGNKGQRLDNR
|.  .| |  || |||||||||||.||...||...|. |.| ....  .. | ..|||.|||.    |.. |..|||  .|||..|.|  ...| |||.|
svleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaataasakkeG.kkdiaeqlikak..kkidvllGGGrkeflptgtkdeekerGtrldgr

NLIEEWqqtKPGNARVVFSRTDLLNNDAQN-TDFLLGLFNASHLAYHM-DDSIDTPTLPEMTAAAINVLSRDPNGYFLFVEGGRIDHAHHETKAKKALDE
|||||.   |   ...|  |..||..  .| ...|||||. ..|.... .|. ..|.| ||| .||..||....|.||.|||.|||||.||..|..||.|
nlieea...kkagyqyvsdrkeLlkakeensvkplLGLFadgdlkvelerdekeePsLkemtevAiklLsknekGFFLlVEGsrIDhaaHendavgalsE

TVQFSDAVRKARQLT-NPWDTLIVVSADHGHTVTISGYPDVNNSIVGLNSELSNVDQLPYTSISYANGPAYERFYKSTDgVVERVDLRNLDFSKpdaiyP
.|.| .||..| ... .  .||.|| ||| |...|.||.  ..|| || . ... |. ....|.|.||....   .. .  |.  .  .  ..|      
vvefdeAvkaalefakkeketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygngegakvedgare.nvtaeealekiyrk.....r

HGVPMTEETHGGGDVAVYAhvveyllQGPWSHLFTGVYEQSTLPHLMGFASCL
  |..|.|.|.| ||||.|       .|| ..|..||.|| .... . .| .|
savgltseeHtgedvavfA.......ygpkaelvrGvqeqteiakvlaaalel
Alk_phosphatase Alkaline phosphatase 64-513 7.5e-127 414.3 In-house 1-421 (421) alignment 
Range on Protein: 64-513
Range on HMM: 1-421/421.0
AKNVIFFLGDGMSVPTVTAGRIFDGQLRGVVGERNrLEFEKFNYVGLSKTYCVNKQVADSACTASAYLSGIKANYLTIGVTadvelndcrgsrLPQNRLS
|||||...||||.|.|||| |.. .| .| .||   |.......|||||||.|.|||.|||.|| ||..|.|..  .|||.              ...  
aknvilligDGmgvstvtaaRslkeqakgklgeei.laldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvd............thgkevk

SIAAWALKGSKSAGLVTTTRVTHASPAGVYAHTSNRDFESDYDVTKLGQNPGnCPDIAQQLIDGDvgKRLRVVMGGGTIKFLPNTTNDVFGNKGQRLDNR
|.  .| |  || |||||||||||.||...||...|. |.| ....  .. | ..|||.|||.    |.. |..|||  .|||..|.|  ...| |||.|
svleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaataasakkeG.kkdiaeqlikak..kkidvllGGGrkeflptgtkdeekerGtrldgr

NLIEEWqqtKPGNARVVFSRTDLLNNDAQN-TDFLLGLFNASHLAYHM-DDSIDTPTLPEMTAAAINVLSRDPNGYFLFVEGGRIDHAHHETKAKKALDE
|||||.   |   ...|  |..||..  .| ...|||||. ..|.... .|. ..|.| ||| .||..||....|.||.|||.|||||.||..|..||.|
nlieea...kkagyqyvsdrkeLlkakeensvkplLGLFadgdlkvelerdekeePsLkemtevAiklLsknekGFFLlVEGsrIDhaaHendavgalsE

TVQFSDAVRKARQLT-NPWDTLIVVSADHGHTVTISGYPDVNNSIVGLNSELSNVDQLPYTSISYANGPAYERFYKSTDgVVERVDLRNLDFSKpdaiyP
.|.| .||..| ... .  .||.|| ||| |...|.||.  ..|| || . ... |. ....|.|.||....   .. .  |.  .  .  ..|      
vvefdeAvkaalefakkeketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygngegakvedgare.nvtaeealekiyrk.....r

HGVPMTEETHGGGDVAVYAhvveyllQGPWSHLFTGVYEQSTLPHLMGFASCL
  |..|.|.|.| ||||.|       .|| ..|..||.|| .... . .| .|
savgltseeHtgedvavfA.......ygpkaelvrGvqeqteiakvlaaalel