Gene CG8105 in Drosophila melanogaster

Synonym: Dmel\CG8105, FBgn0030661, Dmel_CG8105, CG8105

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold AP
Superfamily AP
Family AP
Subfamily AP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP012_AA protein Get Run
DmelP012_AA_40-469 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_AP_pd Subfamily AP 41-469 1.3e-160 525.8 In-house 5-469 (472) alignment 
Range on Protein: 41-469
Range on HMM: 5-469/472.0
HWLRQAQSQLRERLARTkdsiADVRQAKNVVMLLGDGLSITTLTAARILKGQRRGGRGEDAQLAVEQFPFSGLSKTYCIDEQTPDSACTATAYFGGVKTH
 ||..||..|.|.|...    .. ..||||...||||....|.|||||||||..|. ||.|.||.|.||. ||||||..|.|.||||.|||||..||||.
fwlkkaqeelkealelq....snskkakNvilflgdGmgvstvtaaRilkgqlkgelgeeasLaleeFpyvglsktyssdkqvpdsaatAtAylcGvktn

SGTVGQSGS----------GERVDSVLQWAQRAGKATGVVTTTRLTDASPAGAYAHVSRR----GEEL----------EIARQLVEEEPGRNLNVILGGG
.||.| . .          |..|||.|..|..||||||.|||||.|.|||||.||||..|     ||.          .||.||.|||.|..|.||||||
ngtiGvdaaverkdCeasagkevdsileaAkkaGkatGlVtttrvthAsPaglyahvanRnwesdeevpaeaekegckdiaqQLieeevgkeldvilGGG

LGKFA------------DERRDGKDLLAQWRESNPNGCFSRSLKELRNC-TDATGTLLGIFSDSHMSYHLA-ASKELPRLCDMAAAAIEKLERKSqedgN
  ||              ||.||..|...|.... | .. .. |||.|. ...|..|||.|.|||..|...  .|| | | .|...|.| |....    |
rkkflpktvkdseyekkgerkDgrnLieewekekknakyvenrkelenvdksktdrllGlfadshlkyeidrdekeePsLkemtekAlevLskne....n

GYFVFIEGGRIDHGHHETRVGYALDEMVEFDAAVETVIQMTDPRDTLVVVTADHSHTLSMSGYAKRGTPILGMDAQQRDVNGVPYSTLNYAIGKWQSLDK
|.|.|.|||||||.|||..  .||.|..|||.|||.....||..|||.||||||||||...||.|||..|||.. .... ...||.||.|| |....|..
GffLfVEggrIDhahhenkakkaleetlefdeavelaleltdeedTlivvtaDHshtltiagypkrgssilglakesksadelpyttlsyangpgyelte

D----GRRESPSKTL--SPTSYTPSYIHGRKGVHSGEDVVVFAMGPQSHLFGGVMEQNLLPHIMGYAACLGNG
.    |.|......   ... ....... ....|.|||| |.|.||||||. ||.||. ..|.| ||||||..
sdleegerkdlteaeteakdyvsqaavpleeetHggeDvavyasGpqshlltGvveqstiahvmayaaclgea
0037220 Alkaline phosphatase-like 41-469 3.3e-133 435.1 In-house 11-471 (479) alignment 
Range on Protein: 41-469
Range on HMM: 11-471/479.0
HWLRQAQSQLRERLartkDSIADVRQAKNVVMLLGDGLSITTLTAARILKGQRRGGRGEDAQLAVEQFPFSGLSKTYCIDEQTPDSACTATAYFGGVKTH
..|..|. .| . |      ... ..||||....|||....|.|||||..|| .||.||. .||...||..||.|||..|....|||..|||.. ||||.
lllllalallllal....llllnkskaknvilfigDGmgvstvtaariylgqllgglgeegllaldkfplvglvkTysvdslvtDSAaaaTAlatGvKtn

SGTVGQSGS----------GERVDSVLQWAQRAGKATGVVTTTRLTDASPAGAYAHVSRRGEELEIARQLVEEEPG-----------RNLNVILGGGLGK
 |..| . .          |..|...|..|..||||||.|||||.|.|.||. |||| .|. | .||.||.. |.|           ..|.||||||.  
ngaigvdadvsrdncddplgnpvetilelakeaGkatGlVtTtrithATPAafyAhvanRnweddialqllgleagckdiatqlvlgsgldvilGGGrky

F----------------ADERRDGKDLLAQWRESNPNGCFSRSLKELRNCT--DATGTLLGIFSDSHMSYHLAA-SKELPRLCDMAAAAIEKLERksqeD
|                 . | ||.|||....| ...  . ....|| ...  .... |||.|.|||..|.|    .| | | .|. .|.. |..    .
flpkgtldpeydlelllggkrldgrdlleeakekkkgytyvtnreeldaldlgsnvdkllGlfadshlpyeldrdaseePsLaemtekAldlLsk....n

GNGYFVFIEGGRIDHGHHETRVGYALDEMVEFDAAVETVIQMTDPRDTLVVVTADHSHTLSMSGYAKRGTPILGMDAQQrDVNGVPYSTLNYAIGKWQSL
 .|.|...|||||||..|.. . .||.|...|| |||........ ||||||||||||.... |||.||.||||.  .. ...|.||.|| ||.|.. .|
dkGFfLmvEggriDhagHandaaaalgevlafdeaveaalefakdddTlvvvtADHshgglilgyadrgnpilgllpgl.lldglpyttllyangpgfll

DKDGRRES-PSKTLSPTSYTPSYIHGRKGVHSGEDVVVFAMGPQSHLFGGVMEQNLLPHIMGYAACLGNG
  | |       ||... .......   | |.|||| |.|.||...||.||.|.. ..|.. .|..||  
lldlrldltllvtlallllqralvgwtsggHtgedVpvyayGpgaelflgvyentdiahviasalglgll
Alk_phosphatase Alkaline phosphatase 67-466 5.5e-109 355.4 Pfam-A 1-421 (421) alignment 
Range on Protein: 67-466
Range on HMM: 1-421/421.0
AKNVVMLLGDGLSITTLTAARILKGQRRGGRGEDAqLAVEQFPFSGLSKTYCIDEQTPDSACTATAYFGGVKTHSGTVGQSGSGERVDSVLQWAQRAGKA
||||..|.|||.. .|.||||.||.|..|  ||.. ||....|..||||||. |.| .|||.|||||  ||||  |..| .  |..| |||..|..|||.
aknvilligDGmgvstvtaaRslkeqakgklgeei.laldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvdthgkevksvleaAkkaGks

TGVVTTTRLTDASPAGAYAHVSRRGEELEIAR--------------QLVEEEpgRNLNVILGGGLGKF-----AD------ERRDGKDLLAQWRESNPNG
||.|||||.|.|.||. .|||. |  | ..|               ||....  ....|.||||  .|     .|       |.||..|  ....   . 
tGlVtTtrvthAtPaalvahvasRkweddaataasakkeGkkdiaeqlikak..kkidvllGGGrkeflptgtkdeekerGtrldgrnlieeakkagyqy

CFSRSlkELRNCTDAT--GTLLGIFSDSHMSYHL-AASKELPRLCDMAAAAIEKLERKSqedgNGYFVFIEGGRIDHGHHETRVGYALDEMVEFDAAVET
   |.  || . ...     |||.| |... ..|   .|| | | .|  .||..|....    .|.| ..||.||||..||..   ||.|.|||| ||..
vsdrk..eLlkakeensvkplLGLFadgdlkvelerdekeePsLkemtevAiklLskne....kGFFLlVEGsrIDhaaHendavgalsEvvefdeAvka

VIQMT-DPRDTLVVVTADHSHTLSMSGYAKRGTPILGMDAQQRDVNGVPYSTLNYAIGKWQSLDKDGRRE-SPSKTLSPTSYTPSYIHGRKGVHSGEDVV
.....   ..|||||||||||..|..|| .||| | |. | ... .| ..  ..|. |. ...... | . . ...|. .  . | .  ..  |.|||| 
alefakkeketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygngegakvedgarenvtaeealekiyrkrsavgltseeHtgedva

VFAMGPQSHLFGGVMEQNLLPHIMGYAACL
||| ||...|. ||.||. ..... .|..|
vfAygpkaelvrGvqeqteiakvlaaalel
Alk_phosphatase Alkaline phosphatase 67-466 5.5e-109 355.4 In-house 1-421 (421) alignment 
Range on Protein: 67-466
Range on HMM: 1-421/421.0
AKNVVMLLGDGLSITTLTAARILKGQRRGGRGEDAqLAVEQFPFSGLSKTYCIDEQTPDSACTATAYFGGVKTHSGTVGQSGSGERVDSVLQWAQRAGKA
||||..|.|||.. .|.||||.||.|..|  ||.. ||....|..||||||. |.| .|||.|||||  ||||  |..| .  |..| |||..|..|||.
aknvilligDGmgvstvtaaRslkeqakgklgeei.laldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvdthgkevksvleaAkkaGks

TGVVTTTRLTDASPAGAYAHVSRRGEELEIAR--------------QLVEEEpgRNLNVILGGGLGKF-----AD------ERRDGKDLLAQWRESNPNG
||.|||||.|.|.||. .|||. |  | ..|               ||....  ....|.||||  .|     .|       |.||..|  ....   . 
tGlVtTtrvthAtPaalvahvasRkweddaataasakkeGkkdiaeqlikak..kkidvllGGGrkeflptgtkdeekerGtrldgrnlieeakkagyqy

CFSRSlkELRNCTDAT--GTLLGIFSDSHMSYHL-AASKELPRLCDMAAAAIEKLERKSqedgNGYFVFIEGGRIDHGHHETRVGYALDEMVEFDAAVET
   |.  || . ...     |||.| |... ..|   .|| | | .|  .||..|....    .|.| ..||.||||..||..   ||.|.|||| ||..
vsdrk..eLlkakeensvkplLGLFadgdlkvelerdekeePsLkemtevAiklLskne....kGFFLlVEGsrIDhaaHendavgalsEvvefdeAvka

VIQMT-DPRDTLVVVTADHSHTLSMSGYAKRGTPILGMDAQQRDVNGVPYSTLNYAIGKWQSLDKDGRRE-SPSKTLSPTSYTPSYIHGRKGVHSGEDVV
.....   ..|||||||||||..|..|| .||| | |. | ... .| ..  ..|. |. ...... | . . ...|. .  . | .  ..  |.|||| 
alefakkeketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygngegakvedgarenvtaeealekiyrkrsavgltseeHtgedva

VFAMGPQSHLFGGVMEQNLLPHIMGYAACL
||| ||...|. ||.||. ..... .|..|
vfAygpkaelvrGvqeqteiakvlaaalel
Metalloenzyme Metalloenzyme superfamily 285-372 6.2e-07 19.2 Pfam-A 123-212 (252) alignment 
Range on Protein: 285-372
Range on HMM: 123-212/252.0
MAAAAI-EKLERKSQEDGNGyFVFIEGGRIDHGHHETRVGYALDEMVEFDAAVETVIQMTDPRDTLVVVTADHSHTLSMSG--YAKRGTPI
| |..| .|| .. ... .  ||..    .|   |.  |  . . . ..|.... ...  .  |.|...||||.   .| .        |.
msakeitdkllealekgkyd.fvvvnlantDmvGHtgdveakvkaieavDerlkelldavekeddlliitADHgnaeemkdTsHtrepVPv