Gene Pp1-Y2 in Drosophila melanogaster

Synonym: CG41534, DmPp1-Y1, Dmel\CG41534, Pp1Y1, Dmel_CG41534, Pp1-Y1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP1C
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP090_AA protein Get Run
DmelP090_AA_19-288 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0045823 Metallo-dependent phosphatases 20-288 1.6e-103 339.8 In-house 31-329 (473) alignment 
Range on Protein: 20-288
Range on HMM: 31-329/473.0
RIIDTRRLKQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPEN
...  . .|.  |.|.|.. |... .|.....|.|||||... ..||||||..|||||..  |.||. ...||||.|||| .|.|...||||.|||||.|
dlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkikypgn

FFLLRGNHE------------------SXKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPdPKIMG--
.||||||||                  . .|.. |... ...|..|....||...|||||||| ...|| .. ||...|| |||.|||||||   ..|  
vfllrGNHElrllnglygfgdetlekygedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdP.weddgdg

------WSDNDRGVSVTFGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQ------LITIFSAPNYCGEFDNAGAMMSVDETLmCSFYVLKPSKKPG
      .  . ||....||.|.| .| .....|||.|.|..|..|||.. ...      .||.||||||||...| .|.. .||.| .||....||. | 
llrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdpsphpl

L
.
i
0049330 Metallo-dependent phosphatases 23-286 2.4e-102 335.1 In-house 21-302 (309) alignment 
Range on Protein: 23-286
Range on HMM: 21-302/309.0
DTRRLKQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFL
  . ||.  |.| ...||... .|...|.|.|||||... ..||||||..|||||..  |.||. ...||||.|||| .|.|...||||.|..||.|.||
ielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalkllypdnvfl

LRGNHES------------------XKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDND
||||||.                   .||. |.|.....|. |....||.|.|||||||||...|| .| ||...|. |||||||||||.| . |. .|.
lrGNHElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpiregfapnp

RGVSVTFGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKKP
||..|.||...| .|......|||.|.|..|..||..|....|||.||||||||...|.||.. .||.|..||....|.. .
rglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvpll
PP2Ac_SM00156 33-283 4.4e-98 320.6 In-house 2-270 (271) alignment 
Range on Protein: 33-283
Range on HMM: 2-270/271.0
TETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESX--
.. ... |.....|.......|.|.|||| ..||||||..|||||.. .|.|| ..|.|||||||||.||||...||.|.||.|||...||||||||   
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssv

----------------KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGAD
                ...  | ...|..|..|.||.||.| ||||||.| ....| .| |. . |..|||.|||||||. | .|.. . ||.||.||.|
nkiygfeeevkrkygkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFged

IVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPS
.| .|.......||.|||.||..||||||...|.|||||||||.||.|..|...|...|..|. .||. 
avkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlkeq
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 32-283 3.3e-96 314.7 In-house 6-275 (280) alignment 
Range on Protein: 32-283
Range on HMM: 6-275/280.0
LTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESXK
. |.||  . .. ..... |  ..|. |||..|||.|||.|||||||.  ..|| .||||||||||||.| .| ..||||||..||.||..||||||  .
ikeadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevis

------------------LWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGA
                  |.  | . .  .|. |.|  .|.| |||||..|  .... .| || | .|. |  ||||.||. |. ||..| ||||| |||
inrkygfkdevkrryslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvsvifga

DIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPS
..| ..... . |||.| ||||.|||||||...|.|.||||.|.|||||. |.. ||| |. || ||||.
nvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkpa
0053225 Metallo-dependent phosphatases 24-283 1.2e-94 310.0 In-house 14-291 (293) alignment 
Range on Protein: 24-283
Range on HMM: 14-291/293.0
TRRLKQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLL
 . |..  |.|....||..  .|.....|.|||||... ..|||||...|||.|... |.||.....||||.|||| .|.|...||||.|..||.|..||
elllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalkllypdnvvll

RGNHE-------------------SXKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDpKIMGWSDND
|||||                   . .||. ..|.....|..|....||...|||||||| ...||  . ||...|. |||.||||||||  ..||  . 
rGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpd.lwsgwlpsy

RGVSVTFGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPS
||..|.||...| .|......|||.|.|||| |||... ...|.|.||||||.|...|.||.. .|| |...|....|.
rglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfapv
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 31-283 1.7e-87 286.5 In-house 22-295 (297) alignment 
Range on Protein: 31-283
Range on HMM: 22-295/297.0
NLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHE--
 .||  .  | . . .|| .|  ..|. ||.|.|||||||| ||||||  ||.||..||||||||||||. ||||. ||||||.|.| |.||||||||  
viteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhece

-----------------SXKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSP---DLLNMNQIGQLARPCDVpDKGLLCDLLWSDPDPKIMGWSDNDRGVS
                 | ... .| | .  .|.. .. .||.| ||||||   . . .. . .. |. .   ..|..||||.||   . |. .|.||  
fvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisglsgfmenqrgag

VTFGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPS
. || | | | .   |.||.|||||||.||||||| |.|.|||||| |||.|||. |.||.|| | ||| .|.|.
cgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeilrpt
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 29-285 3.2e-83 272.2 In-house 5-279 (281) alignment 
Range on Protein: 29-285
Range on HMM: 5-279/281.0
QLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHE
....|. .|  .    . .|...  | |. .|... ||.|.||.|| |||.  | .|   ..|||||||||.||.|.. ||...||.|... .|||||||
kvqytkeeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnhe

SX------------------KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVT
                    .||  |  |.  .|.|| ..... | ||||||.| ..... .  .|.. .|.||. ||||.|||.| ..|    ||.| |
iasvnkiygfyvecvtkyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssft

FGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKK
|| ..| .   | . .|| |||||| |||| .. |.|||.||.||||  . ||.|.. |||||  |.  | |. .
fGknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislvalvpase
subfamily_PPP1C_pd Subfamily PPP1C 130-285 6e-83 271.3 In-house 126-281 (282) alignment 
Range on Protein: 130-285
Range on HMM: 126-281/282.0
XKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLIC
 |||.||.|...|.|..|.|||||.|.||||||.| ...|| ...||..||.||||||||||||| ...|||.||||||.|||.|.| ||......|||.
iklWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendrGvsftfgkdvvekflqkndldliv

RAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKK
||||||||||||||||||.|.|||||||||||||||..||||.|..|| .|||.||
rahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilkpakk
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 87-283 9e-79 257.9 In-house 101-315 (317) alignment 
Range on Protein: 87-283
Range on HMM: 101-315/317.0
SNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESX------------------KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMN
..|||||||||||  ||| . ||.|.|..||.. |||||||||                   .|. .|   . ..|..|.|..||.| |||.| .||...
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldlk

QIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMS
|. .| ||.|.|| |.|.|| |.|||... |. .  || .  |||. | .|......||. |||||||||||||| |.|.||||||.|||..||..|..|
qldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavls

VDETLMCSFYVLKPS
||. |..|. ||.|.
vdkklkisinvlrpe
subfamily_PPP3C_pd Subfamily PPP3C 27-274 8.5e-70 228.7 In-house 36-314 (452) alignment 
Range on Protein: 27-274
Range on HMM: 36-314/452.0
LKQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGN
||. .|.|...  . ... ... ... |||..||. ..||||||| |||.||. || |  ..|||||||||||  |||..  |.| ||.||...||||||
lkegrleeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGn

HESXKL------------------WRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIM------GWSD
||. .|                  . ...... ..|..|..... .|.||||||.. ....| .| |  ..| .|.|||||||||  .         .. 
hecrhlteyftfkeeckikyseevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfvp

-NDRGVSVTFGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAK------RQLITIFSAPNYCGEFDNAGAMMSVDETLM
 . || |. ..   | .|... ..  | |||.. ..||. . |        |||.||||||.. ..| .|.. ...  |
nsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennvm
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 130-285 3.1e-66 216.4 In-house 141-296 (298) alignment 
Range on Protein: 130-285
Range on HMM: 141-296/298.0
XKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLIC
 .|. .| | .. .|. |.. ..|.| |||||. | ...|. .| || | ... |  ||||.||. .. ||..| |||||.||.| | ..... . ||..
lrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadpenavkgwaensrGvsvvfGedvvkdllekldidlvv

RAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKK
|||||| |||||||...|.||||||.|||.|||. |.|.||| |..|| ||||.||
rahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkpekk
subfamily_PPP5C_pd Subfamily PPP5C 31-282 3.1e-64 210.0 In-house 33-308 (322) alignment 
Range on Protein: 31-282
Range on HMM: 33-308/322.0
NLTETDIRLLCNRSREVFMSQPMLLELSAP----VKICGDIHGQFTDLLRLFDYGGYPPAS-NYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRG
.| .  .  .  ...|.. ..| |.|.. .    . .|||||||| ||| .|.  |.|  .  ||| ||.||||  |.|.. .||..|. ||..||| ||
klhkkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrG

NHESXKL------------------WRTFVDCYSCMPVSAIVDEKIFCCHGGL-SPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKiMGWSDNDRG
|||| ..                     | . .. .|.. ...||.. .|||| | | ...... .. | .. |..|||..||||||... .| |   ||
nhesdnmnklyGfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqea.nGrspskrG

VSVTFGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSV-DETLMCSFYVLKP
|.|.|| |.  ||..  ...|| |.|.| |.|||.  . .|||.||||||| . .| ||.... .. |   |   . 
vgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfea
subfamily_PPZ_pd Subfamily PPZ 131-284 5.3e-63 206.3 In-house 142-295 (300) alignment 
Range on Protein: 131-284
Range on HMM: 142-295/300.0
KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICR
|.|.|||| .  .|..|||  |||| |||||| | .|..| ...|| |||| ||. |||||||      | ||.||||  .    . ||. .  |||.||
kiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptdssnewednergvsycynkvainkflnkfgfdlvcr

AHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSK
|| |||||||||  | |.|.|||||||||||| ||.||| | |.||| .| |  
ahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfelldpld
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 28-282 9.6e-63 205.2 In-house 16-291 (307) alignment 
Range on Protein: 28-282
Range on HMM: 16-291/307.0
KQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNH
.... |  ..  .   .. .| |.  |...  |. . ||.|||| ||. .|   | || . |.| |||||||  |.|.. ||..||| ||||  ||||||
hkiqytkeefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnh

ES---------------------XKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRG
|                       ..|  |  |.  .|.||..  ||.| |||||| |  .... .  .|   | .|.. |.||.|||| .. |    ||
eiarvnkkygfyeecvtsipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrg

VSVTFGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKP
  .|||....   ..|   .|| ||||.. |||  .. |.|||||||| ||  . |||... |||||      . |
sgftfgtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgiqlvafvp
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 129-285 2.4e-62 203.9 In-house 140-296 (299) alignment 
Range on Protein: 129-285
Range on HMM: 140-296/299.0
SXKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLI
| .||  | |... ||.. ..  .|.| |||||| | ...|. .|.|| | |.  |  ||||.|||  ...|  | ||||  || |.| . ..| . ||.
strlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqsvkdwlanvrgvsyvfgqdvvadvisrldidlv

CRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKK
.||||||.|||||||...|.|||||| |||.|||. |.| ||| |.|.|.||||..|
arahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptpk
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 129-282 1.9e-61 201.0 In-house 129-282 (284) alignment 
Range on Protein: 129-282
Range on HMM: 129-282/284.0
SXKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLI
| .|. .|  .. .||..|.|..||.| |||.| |||...|. .| ||.|.|| |...|| |.||. ...|. . .||   .|||. | .|....|.||.
sealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegykesprgagkvfgakavkeflkkfkldlv

CRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKP
 |||||| ||||||| |.|.|||||| |||..||..|...||| |..|| ||||
vrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlkp
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 88-284 9.6e-57 185.6 In-house 121-335 (339) alignment 
Range on Protein: 88-284
Range on HMM: 121-335/339.0
NYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESXK------------------LWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQ
 |||||||||||  |.| . || | |. ||.  .||||||||                    |.  | . .  .|. |.... |.| |||.|  |  .||
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyrydaqlyecfqnmfnvfpfcavinntimcmhggisehltsfnq

IGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSV
.  . || ..|| |.| || |.||||   |.    || |. ||   .  |...  .... | |||||||||||  |.|.||||||||||. ||. |..|.
fsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfsi

DETLMCSFYVLKPSK
|. |  |  |..|  
dkklkisinvfrpes
subfamily_PPP1C_pd Subfamily PPP1C 25-130 4.1e-55 180.0 In-house 3-108 (282) alignment 
Range on Protein: 25-130
Range on HMM: 3-108/282.0
RRLKQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLR
.. |...|.|..|. |....||...|||.||||.|||||.||||||..||||||...|.||.||||||||||||||||.||..||||||||||||.||||
kkgkevklkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllr

GNHESX
||||| 
Gnhesa
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 132-290 6.6e-54 176.2 In-house 122-281 (284) alignment 
Range on Protein: 132-290
Range on HMM: 122-281/284.0
LWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKG-LLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICR
.. .|   .| ||..|.| ..|.| |||.|  | |. |.  . || | |.   |  |.|||||     ||  | ||||  ||.| . |.. | . ||. |
vyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvfgsdalrklldrlqidlvvr

AHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKKPGLRK
|||||.|||||||.|.|.|||||| |||.|||| |.| |.. |.||| ||.| ||   |.
ahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlrprkkiarrr
PPP_3 130-280 1.1e-52 171.7 In-house 119-269 (271) alignment 
Range on Protein: 130-280
Range on HMM: 119-269/271.0
XKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLIC
 |..... ......|..|..|||....||||||.. ...|| .| |...||..|.|.|||.|... |  |.. ..||....||.|.. .|....|..||.
kkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFgpdvteefleknkLklii

RAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVL
|||...|.|||........|.|||||||....||||.....|.|...| .|
RaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkql
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 16-130 4e-50 163.5 In-house 5-122 (298) alignment 
Range on Protein: 16-130
Range on HMM: 5-122/298.0
QLILRIIDTRRL---KQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAY
.|..... .          ..|.|.  |.. ....| .|..|.|. ||.|.|||||||..||||||| .|.|| .||||||||||||.|..|...|||||
ellievlsvslsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllay

KIKYPENFFLLRGNHESX
|.|||.||||||||||  
kvkypnnffllrGnhece
subfamily_PPP2C_pd Subfamily PPP2C 131-286 5.8e-50 163.1 In-house 135-289 (290) alignment 
Range on Protein: 131-286
Range on HMM: 135-289/290.0
KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDpKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICR
..|. | | . ..|..|.|||.||| |||||| .  ...| .| |  .||..| ||||||||||    ||.  .||   ||| ||  || .. .. || |
nvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpd.drggwgisprgagytfgkdisekfnktngltliar

AHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKKP
|||.| .||..  .|...|||||||||    | .|.. .|..|  ||   .|. . 
ahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdpaprr
subfamily_PPZ_pd Subfamily PPZ 14-130 1.4e-48 158.9 In-house 3-123 (300) alignment 
Range on Protein: 14-130
Range on HMM: 3-123/300.0
IDQLILRIID----TRRLKQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLL
||..| ...|    ..| |.. | ...|  .| ..||.|..|| ||||| .||| ||.|||..||||||   |.||..|||||||||||||||.||. ||
ideiiqklldagyaakrtknvclknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletilll

LAYKIKYPENFFLLRGNHESX
|.|||||||||||||||||  
lcykikypenffllrgnheca
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 131-285 4e-48 157.3 In-house 123-277 (280) alignment 
Range on Protein: 131-285
Range on HMM: 123-277/280.0
KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICR
 ||  |  |.  ||.|... ....| ||||||.|.|.. | .. |||.  |.||| |||||||  |  ||  . ||.|  ||  .| . ..  . ||| |
glwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisymfgkgvveqacksleidliir

AHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKK
|||||.||||..| |.|||.|| |||| .| || |.. ..  |  ||  | |   
ahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqqlipppl
PPP_1 130-269 1.1e-47 155.5 In-house 118-264 (264) alignment 
Range on Protein: 130-269
Range on HMM: 118-264/264.0
XKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLL-------WSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHR
 ....|..|.. ..|..|..||||...||||||.|  ..|| .. |  .||..| |||||       .||.. . .......||.. .||.|.. ||...
keiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRGagylfgkdvtekflqk

HKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSV
....||.|||.|.|.||||..||...|||||.||. |..|.||....
nnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvkl
subfamily_PPP4C_pd Subfamily PPP4C 130-281 1.2e-47 155.5 In-house 133-283 (288) alignment 
Range on Protein: 130-281
Range on HMM: 133-283/288.0
XKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDpKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLIC
 ..||  .. .  ....||.|.|||| ||||||.. ....| .. |  .||..| |||||||||. .. ||.   ||    ||.|.| .|... ...|||
anvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpe.daegwavsprgagylfgsdvveqfneandielic

RAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLK
||||.| .|| .  .....|..||||||    |  |.. .||.|   | ...
rahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkife
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 14-129 6.5e-45 146.6 In-house 3-121 (299) alignment 
Range on Protein: 14-129
Range on HMM: 3-121/299.0
IDQLILRIIDTRRL-KQL--NLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLL
.|.|......     |.|  .. | ... ||. ...||.||. |||. ||...|||||||..||||.||  |.|| .|.||||||||||.| .|...|||
vdellskllnvgmsekrltksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlll

AYKIKYPENFFLLRGNHES
..||||||.||.|||||| 
cfkikyperffmlrgnhec
PPP_1 34-131 1.4e-44 145.4 In-house 3-100 (264) alignment 
Range on Protein: 34-131
Range on HMM: 3-100/264.0
ETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESXK
|. .. |.....|.......|||.|.....||||||||.|||.|| .|| .| .|||||||||||||.|.|...||||.|.|||...||||||||| .
eeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrq
PPP_3 32-131 2e-43 141.3 In-house 2-101 (271) alignment 
Range on Protein: 32-131
Range on HMM: 2-101/271.0
LTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESXK
|.|.... |... .|.......|.|.||||..|||||||..|||.||..|| .| ..||||||||||||.|.|...||||.|||||....|||||||| .
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 131-284 3.3e-43 140.6 In-house 127-283 (287) alignment 
Range on Protein: 131-284
Range on HMM: 127-283/287.0
KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDV--PDKGLLCDLLWSDPDPKIMGWSDN-DRGVSVTFGADIVGKFVHRHKFDL
.|...| | .| .|. |.|...|.| |||.||.|  ....  | .|      |.||  ||||.||. .  .   |  |..|| ||   | ..... . ||
rlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkkevddllkkldidl

ICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSK
| |||.|.|.||.|.....|.|.|||| |.||  | ||.. |...|  || |||| .
ivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkped
subfamily_PPP6C_pd Subfamily PPP6C 131-273 9.1e-43 139.4 In-house 133-274 (290) alignment 
Range on Protein: 131-273
Range on HMM: 133-274/290.0
KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPDpKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICR
. |. ... .  ....||.||...| |||||||.  ..||  . |  ..| || .|||.||||. ..  |.  .||    ||. .. .|||  ...||||
nawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdpe.dvetwavsprgagylfgskvtkefvhinnlklicr

AHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETL
|||.||.|.... . .|.|..||||||    |  ........ 
ahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledae
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 35-132 5.9e-39 127.2 In-house 6-103 (284) alignment 
Range on Protein: 35-132
Range on HMM: 6-103/284.0
TDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESXKL
 |.  |  .. ..|  ||||.|  .|..|||||||||.|||||||  |.|  .|||||||||||||. .||. ||.|||. .|. ||.||||||   .
edvetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecsli
subfamily_PPP4C_pd Subfamily PPP4C 31-131 1.2e-37 122.7 In-house 15-115 (288) alignment 
Range on Protein: 31-131
Range on HMM: 15-115/288.0
NLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESX
 ..|.... ||...||... .  . .. .|| .|||||||| |||.||. ||  |  |||||||.||||. |.||. ||||.|..||..  |.|||||| 
likeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesr

K
.
q
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 32-131 1.6e-37 122.5 In-house 8-113 (284) alignment 
Range on Protein: 32-131
Range on HMM: 8-113/284.0
LTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYP------PASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRG
|.|...  || |.||.|  ... ||. |||||.||||||| ||| |.|  |.|        ..|||||||||||  ||| . ||.|||...|.. |||||
lkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllrg

NHESXK
||||  
nhesrp
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 130-283 2.2e-36 118.4 In-house 132-289 (290) alignment 
Range on Protein: 130-283
Range on HMM: 132-289/290.0
XKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCD--VPDKGLLCDLLWSDPDP-KIMGWSD-NDRGVSVTFGADIVGKFVHRHKF
 .||. . | .. ... | |..||.| |||.|...   . .  | .|      |.||  ||||.||.  |    .    |..|| || . . .....  .
srlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialnkqraisvvfgkkglddllkklal

DLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPS
.|| |||.| |.|..|  ...|.|.|||| |.|.  | ||.. | |.|  |. |||| 
slivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvlkpr
subfamily_PPP2C_pd Subfamily PPP2C 14-131 2.8e-36 118.2 In-house 4-116 (290) alignment 
Range on Protein: 14-131
Range on HMM: 4-116/290.0
IDQLILRIIDTRrlkqlNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYK
.|.|| .. ...     .|.|.... ||.. .|.....  . |...|| .|||.|||| ||| ||  ||  | .||||||||||||  |.||..|| | |
ldklieklkeck.....qleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalk

IKYPENFFLLRGNHESXK
..|.|   .||||||| .
vrykeritilrgnhesrq
subfamily_PPG1_pd Subfamily PPG1 131-279 5.9e-36 117.2 In-house 133-292 (300) alignment 
Range on Protein: 131-279
Range on HMM: 133-292/300.0
KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLLWSDPD---------PKIMG--WSDNDRGVSVTFGADIVGKF
..|. . . .  . ..||.||.|.| ||||||. | ..||  | |  .||..| |.|||||||.         |   |  .   .||   ..| |.| ||
rvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhpdregqhfvvsqrgagysygkdvvekf

VHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYV
..  ... | ||||.. .||. .   .| |..||||||    |  ... . | .   | |
lrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnv
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 133-283 2.4e-35 115.4 In-house 104-256 (263) alignment 
Range on Protein: 133-283
Range on HMM: 104-256/263.0
WRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPD-KGLLCDLLWSDPDPKIMGWSDND-RGVSVTFGADIVGKFVHRHKFDLICR
.  | . .| ||. ||| ..|.| |||.|| | ....|  .  | .    . | |||||.||.    |.  |  | .|  ||   |  ...|   ||| |
ynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidlivr

AHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPS
|||||| || ||| |.|||.|||  |  |. |  |.. |.. |  ||  ||| 
ahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlkpe
PPP_2 61-131 3.2e-35 114.6 In-house 1-71 (198) alignment 
Range on Protein: 61-131
Range on HMM: 1-71/198.0
VKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESXK
|..|||.|||..|||.||..|. .| ..||||||||||||.|.|...||||.|..||....|||||||| |
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskk
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 131-284 3.8e-35 114.5 In-house 138-301 (302) alignment 
Range on Protein: 131-284
Range on HMM: 138-301/302.0
KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPC-DVPDKGLLCDLLWSDPDP--KIMG------W-SDNDRGVSVTFGADIVGKFV
..|. | ...| ||..|.| |||.| |||.|| |  ...| .. ||  .| .  |  |||..||    ...       .  .. ||.||.|    | .. 
eiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvqllaavsekPkyaknivrglsvvfneaavrdvc

HRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSK
.|  ..|| ||||..  |. |||...|.||||||.|  | || ||.. ||     |  ||.. |
krlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrnkk
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 130-282 5.8e-35 113.9 In-house 138-300 (302) alignment 
Range on Protein: 130-282
Range on HMM: 138-300/302.0
XKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPC-DVPDKGLLCDLLWSDPDP--KIMG------W-SDNDRGVSVTFGADIVGKF
 ..|. | ...| ||..|.| |||.| |||.|| |  ...| .. ||  .| .  |  |||..||    ...       .  .. ||.||.|    | ..
keiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvqllaavsekPkyaknivrglsvvfneaavrdv

VHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKP
 .| ...|| ||||..  |. |||...|.||||||.|  | || ||.. ||     |  ||..
ckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrn
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 32-131 1.5e-34 112.2 In-house 10-109 (287) alignment 
Range on Protein: 32-131
Range on HMM: 10-109/287.0
LTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESXK
....||  . .. .|..   | |||. ||..|.||||||. ||||.|.  |..|  .||||||||||| .|.| . ||...||.||..  |||||||  |
fsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhevkk
subfamily_PPP6C_pd Subfamily PPP6C 31-132 1.7e-34 112.3 In-house 14-115 (290) alignment 
Range on Protein: 31-132
Range on HMM: 14-115/290.0
NLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESX
 |.|.|.. ||..  .... .  .  .|.|| .|||||||| ||. ||  ||  | ..|.||||.||||  |.||. .||. |.|||..  |||||||| 
ylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesr

KL
..
qi
Metallophos Calcineurin-like phosphoesterase 60-234 2.5e-34 112.3 Pfam-A 2-198 (200) alignment 
Range on Protein: 60-234
Range on HMM: 2-198/200.0
PVKICGDIHGQFTDL----LRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLL--LAYKIKYPENFFLLRGNHESXK----------------------
.. ..||.||.. ||    |.|.. ...... ..|||||.||||. |.|| .||  |..|...| ..|||||||||                        
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange

------------------------------LWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIgqlarpcdvpdkgllcdllwsdpdpkimgws
                               .. . ... ..|  |.|| ||...||.||... . ..|                               
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................

dndrgVSVTFGADIVGKFVHRHKFDLICRAHQV
      |. || | . |.  ... ||..|.|. 
.....gselfgpdalekllekygvdlvlrGHtH
PPP_4 61-131 1.3e-33 109.7 In-house 1-73 (197) alignment 
Range on Protein: 61-131
Range on HMM: 1-73/197.0
VKICGDIHGQFTDL-LRLFDYGGYPP-ASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESXK
| ..||||||..|| |.|...|| |.  ..|.||||||||||.|.|...||||.|..||....|||||||| .
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEsks
subfamily_PPG1_pd Subfamily PPG1 31-137 2.2e-33 108.8 In-house 13-119 (300) alignment 
Range on Protein: 31-137
Range on HMM: 13-119/300.0
NLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESX
 | |. .. |... .|.....  . |. .|| . ||.|||| |.| .|. ||  | .||||||||||||  |.||. ||.. |..||    |||||||| 
llpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgnhesr

KLWRTFV
.. ... 
qitqvyg
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 32-131 5.3e-32 104.0 In-house 16-115 (290) alignment 
Range on Protein: 32-131
Range on HMM: 16-115/290.0
LTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESXK
... ||  . .. .|..   | |||. ||. | ||||||. .||| ||  ||||  ..|||||||||| .|.|   ||. |||.|...  |||||||  |
fsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhevrk
PPP_5_Dcr2 61-131 8.7e-32 103.7 In-house 1-73 (199) alignment 
Range on Protein: 61-131
Range on HMM: 1-73/199.0
VKICGDIHGQFTDL-LRLFDYGGYPP-ASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESXK
| .|||.|||. || |.||. || |.   .|.||||||||||.|.|...||||.|..||....|||||||. .
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeq
PPP_2 130-234 1e-29 96.7 In-house 89-197 (198) alignment 
Range on Protein: 130-234
Range on HMM: 89-197/198.0
XKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDKGLLCDLL----WSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKF
 |..... ......|..|..|||....|||||... ...|| .  |....|..|.|.|||    .|||. |  ... . ||....||.|.. ......|.
kkvykklqevfelLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknkl

DLICRAHQV
.||.|||.|
kliiRaHev
PPP_4 130-234 4.8e-29 94.8 In-house 90-196 (197) alignment 
Range on Protein: 130-234
Range on HMM: 90-196/197.0
XKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVP-DKGLLCDL-LWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDL
 ...... |.....|..|..|||....|||||..| ....| ...|....| ......|| ||||| ..  |.... ||....||.|.. ||.......|
keilkklqdvfdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkl

ICRAHQV
|.|.|..
iirshel
PPP_5_Dcr2 131-235 1.9e-27 89.5 In-house 92-199 (199) alignment 
Range on Protein: 131-235
Range on HMM: 92-199/199.0
KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVP-DKGLLCDL-LWSDPDPKIMG-WSDNDRGVSVTFGADIVGKFVHRHKFDL
|..... |.....|..|..|||....||||||.. ..... ...|....| .||  .|| ||||| ..  | .  . ||....|| |.. ||.......|
kiykilsdvfdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkl

ICRAHQVV
|.|.|...
iirshelk
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 28-130 2.3e-27 89.0 In-house 2-115 (302) alignment 
Range on Protein: 28-130
Range on HMM: 2-115/302.0
KQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGG----------YP-PASNYLFLGDYVDRGKQSIETMCLLLAYKIKY
.. ....... ||..   | .  .  | |.|.|| | ||||||| ||.|.. .            |    . ..|||||||||..||| .||..|.|. |
rkkeysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvly

PENFFLLRGNHESX
|.|. |||||||. 
ptnyillrgnhetk
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 28-130 2.5e-27 88.9 In-house 3-116 (302) alignment 
Range on Protein: 28-130
Range on HMM: 3-116/302.0
KQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGG----------YP-PASNYLFLGDYVDRGKQSIETMCLLLAYKIKY
.. ....... ||..   | .  .  | |.|.|| | ||||||| ||.|.. .            |    . ..|||||||||..||| .||..|.|. |
rkkeysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvly

PENFFLLRGNHESX
|.|. |||||||. 
ptnyillrgnhetk
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 43-129 6.9e-26 84.3 In-house 17-103 (280) alignment 
Range on Protein: 43-129
Range on HMM: 17-103/280.0
RSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHES
    .|| .  | |  ||.|. |||| |. |. ||||  |  |  . .||||||||| | || . ||.. ||.| .  .|||||||.
mveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhet
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 54-130 2.1e-25 82.8 In-house 2-78 (263) alignment 
Range on Protein: 54-130
Range on HMM: 2-78/263.0
LLELSAPVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESX
|||| ||..|||| |||. ||||.|.  |    ..||||||||||| .|.| . ||.. |.  | ...|||||||  
llelqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelk
subfamily_PPPLV_pd Subfamily PPPLV 131-272 7.3e-25 80.8 In-house 121-278 (290) alignment 
Range on Protein: 131-272
Range on HMM: 121-278/290.0
KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLAR-----PCDVPDKGLLCDLLWSDPDPK-----------IMGWSDNDR-GVSVTFGA
. | .| ...  .|..|..|.|.||.|.|.        .|  .       . |.    |  |.|||||. .             |. |||| | .  |..
evweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvlneGfvdndrrGtghvfse

DIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAgAMMSVDET
| . .|..|   . . |||.| | |...  | .|.|.||. .|||  ..| |.. ||. 
daleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssnea.alilvdkk
subfamily_PPP7C_pd Subfamily PPP7C 20-129 1.9e-24 79.1 In-house 22-135 (383) alignment 
Range on Protein: 20-129
Range on HMM: 22-135/383.0
RIIDTRRLKQlNLTETDIRLLCNRSREVFMSQPMLLE----LSAPVKICGDIHGQFTDLLRLFDYGGYPPASN-YLFLGDYVDRGKQSIETMCLLLAYKI
..|.. ..|.  |    . |.   ...|. . | . .    .|  | .|||.||.. ||| ..   |.| ..| |.| ||.|||||.|.| ...|||. .
klieafkekk.llhakyvllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalll

KYPENFFLLRGNHES
 ||....| ||||| 
vypkevylnrGnhed
subfamily_PPPLV_pd Subfamily PPPLV 40-128 1.6e-22 73.2 In-house 5-97 (290) alignment 
Range on Protein: 40-128
Range on HMM: 5-97/290.0
LCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLL----RLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHE
||. . ......  |||| .|. . ||.||.. ||      |.  |     ...||||||||||. |.| .. ||| |. ||  ..|||||||
lcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhe
subfamily_PPP7C_pd Subfamily PPP7C 185-281 1.1e-21 70.0 In-house 237-333 (383) alignment 
Range on Protein: 185-281
Range on HMM: 237-333/383.0
LCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLK
. |.|||||  |   ...  ||  . ||.|.  |........|. |.|.   .||||  .....||||| ||  |  | || . . ..|.  ..  .
vldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltprivqyq
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 32-87 5e-18 58.3 In-house 9-64 (317) alignment 
Range on Protein: 32-87
Range on HMM: 9-64/317.0
LTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPAS
..|...  || |.||.| ..|. ||| |||.|.||||||| ||| |.|  |.| .|
fkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwplss
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 35-87 2e-13 43.1 In-house 14-66 (339) alignment 
Range on Protein: 35-87
Range on HMM: 14-66/339.0
TDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQFTDLLRLFDYGGYPPAS
...  || |.||.  |.|..|.| ||. . ||||||| ||| ..|  |.| .|
aelaelchrareliwsepiflkleapicvmgdihgqfddllamldmngwplss
subfamily_PPP7C_pd Subfamily PPP7C 130-175 1.6e-06 20.1 In-house 157-201 (383) alignment 
Range on Protein: 130-175
Range on HMM: 157-201/383.0
XKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSpDLLNMNQIGQLAR
 |. |.. | .. .|.....||||. .|||.| |  ... . ...|
kkilrlledvfawlplatlidekilivhGGis.dktdlelldkier
subfamily_YNL217W_pd Subfamily YNL217W 63-131 4.1e-06 19.5 In-house 14-78 (235) alignment 
Range on Protein: 63-131
Range on HMM: 14-78/235.0
ICGDIHGQFTDLLRLFD--YGGYPPASNYLFLGDYVDRGKQSIETMCLLlaykikYPENFFLLRGNHESXK
. ||.|| . .|..|.|   ||  .    ...|| ...| .|.|.. ..        ..   ..||||   
vvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelv