Gene Pglym78 in Drosophila melanogaster

Synonym: CG1721, Dmel\CG1721, PGAM, PGLYM, Pglym, pglym78, Dmel_CG1721, Pglym78

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily PGAM
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP106_AA protein Get Run
DmelP106_AA_4-252 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PGAM_pd Subfamily PGAM 5-253 8.7e-119 387.3 In-house 1-248 (248) alignment 
Range on Protein: 5-253
Range on HMM: 1-248/248.0
YKIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASILKASGHKEIPIQKTWRLNERHYGGLTGLNKAET
.|.|..||||||.|..|.||||.||.|||||.||| .||||.|.|.||||...||||.||| ||. ||... .. ||..|||||||||||.||||||||.
iklvllRhGeselnkenkfcgwvDakLsekGkeeAkkagkalkqanlefdivytSvlkRaqqTlevileeldqekiPvektwrLnErhyGaltglnkaev

AAKYGEAQVQIWRRSFDTPPPPMEPGHPYYENIVKDPRYAEgPKPEEFPQFESLKLTIERTLPYWNDVIIPQMKEGKRILIAAHGNSLRGIVKHLDNLSE
|.||||..|.|||||.|..|||.|  ..|...|.||.||.|  |.||.|. |||| ..||.||..|..|....|||||.||.|||||.|...|.|...|.
akkyGeekvkiwRRsydvkPPpveedkeyfkeinkdrryee.lkeeelPesEslkevveRllpvlneeilkeikegkrvlivahgnsvrallkvlegisd

DAIMALNLPTGIPFVYELDENFKPVVSMQFLGDEETVKKAIEAVAAQGK
.||..|.||||||.|||||||.|||...|||||||.||||.||||.|||
eaikeldlptgiplvyeldenlkpvkkkqflgDeesvkkaaeavanqgk
0043909 Phosphoglycerate mutase-like 5-244 2.9e-75 245.0 In-house 3-243 (249) alignment 
Range on Protein: 5-244
Range on HMM: 3-243/249.0
YKIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASILKASGHKEIPIQKTWRLNERHYGGLTGLNKAET
.....|||||.|||....|.||.|..|.|.| |.| |.|.|.|..|. ||....| |.||. |.. ||.. |.  .|.....||.||..| |.||.|||.
krlyLvRHGetewnaegrfqgwlDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileelgldklpvevdprLrErdfGalegltkaei

AAKYGEAQVQIWRRSFDTPPPPMEPGHPYYENIVKDPRYAE-GPKPEEFPQFESLKLTIERTLPYWNDVIIPQMKEGKRILIAAHGNSLRGIVKHLDNLS
|.||.|..|...|||.|..||..|. .... ....|...|.  |    .|. |||. ...| ||...... ...|.|...|| |||..|| ....| .||
aekypeelvawlrrsydvlpplleeldelllellldyaladldplldrppggEsladvvaRvlpaleellarllkdggnvliVaHggvlrallayllgls

EDAIMALNLPTGIPFVYELDENFKPVVSMQFLGDEETVKKA
 ..|. ||||.|...|.|||.. ||||....|.| . ... 
ledilrlnlpngsitvlelddggkpvvvlvllndtshleal
0036777 Phosphoglycerate mutase-like 6-252 6.7e-71 230.9 In-house 4-246 (247) alignment 
Range on Protein: 6-252
Range on HMM: 4-246/247.0
KIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASILKASGHKEIPIQKTWRLNERHYGGLTGLNKAETA
....|||||.|||. ..|.||.|..|.|.| |.| |.|...|..|| ||....| |.||. |.. ||.| |.  .|.....||.||.|| |.||.|||.|
rlyLvRHGetewnaegrfqgwlDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiilealglsllpvvvdprLrErdyGalegltkaeia

AKYGEAQVQIWRRSFDTPPPPMEPGHPYYenIVKDPRYAEGPkPEEFPQFESLKLTIERTLPYWNDVIIPQMKEGKRILIAAHGNSLRGIVKHLDNLSED
.||.|..|..||...|..||..|. ....  .....|||  |   ..|. |||. ...| ||...... ...|.|...|. .||..|| ....| .|| .
ekypeelvawwrdpydyrppllelllell..lldllryallp.ldllpggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllglsle

AIMALNLPTGIPFVYELDENFKpVVSMQFLGDEETVKKAIEAVAAQG
.|. ||||.|...|.|||.. | ......|.| . .....||||..|
dilrlnlpngsitvleldddgk.lwvleslndtshlelgleavadfg
0049178 Phosphoglycerate mutase-like 5-232 8.6e-67 217.4 In-house 4-226 (243) alignment 
Range on Protein: 5-232
Range on HMM: 4-226/243.0
YKIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASILKASGHKEIPIQKTWRLNERHYGGLTGLNKAET
.....|||||.|||... ..||.|..|.|.|.|.| |.|.. ...|| ||....| |.||. |.. ||.| |.. .|.....||.||..| |.||.|||.
trlyLvRHGetewnaegrlqgwtDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiilealglpllpvvvdprLrErdfGalegltkaei

AAKYGEAQVQIWRRSFDTPPPPMEPGHPYYENIvkDPRYAEGPKpeeFPQFESLKLTIERTLPYWNDVIIPQMKEGKRILIAAHGNSLRGIVKHLDNLSE
||||.|..|..||...|..||.... ..... .  |...|.      .|. |||. ...| ||...... .....||..|. |||...| ....| .|. 
aakypeelvawwrdpydarppalllldlllpll..drlladldl...lpggEsladvaaRvlpaleellaellhdgktvlvVaHggvirallalllglpl

DAIMALNLPTGIPFVYELDENFKPVVSM
.... ||||.| ..|.|||...  .||.
eellrlnlpngsvtvlelddggwvlvsl
0051064 Phosphoglycerate mutase-like 5-240 1.6e-63 207.0 In-house 4-235 (241) alignment 
Range on Protein: 5-240
Range on HMM: 4-235/241.0
YKIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASILKASGHKEIPIQKTWRLNERHYGGLTGLNKAET
.....|||||||||  . ..||.|..|.|.|.|.| |.|.. .|.|. ||....| |.||. |.. |..| |.. .|.. ..||.|...| |.||...|.
krlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaealglpllpvvvdprlrEidfgalegltleei

AAKYGEAQVQIWRRSFDTPPPPMEPGHPYYenIVKDPRYAeGPKPEEFPQFESLKLTIERTLPYWNDVIIPQMKEGKRILIAAHGNSLRGIVKHLDNLSE
|.|..|..|...|...|..||..|. ....  .. |.||| | ... .|  |||. ...| ||...... .....||..|. .||...| ....| .|. 
aekfpeelvawlrdpldvrppllelldlll..llldlrya.gllddllpggEsladvaaRvlpaleellarllldgknvlvVsHggvirallayllglpl

DAIMALNLPTGIPFVYELDENFKPVVsMQFLGDEET
.... ||||.| ..|.|||...|.|| ...|.| ..
eellrlnlpngsvtvleldddgkrvv.lvllndtsh
0048955 Phosphoglycerate mutase-like 6-237 1.6e-62 203.7 In-house 2-230 (240) alignment 
Range on Protein: 6-237
Range on HMM: 2-230/240.0
KIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASILKASGHKEIPIQKTWRLNERHYGGLTGLNKAETA
....||||||||| .. ..||.|..|.|.|.|.| |.|.. .|.|. ||....| |.||. |.. |..| |.. .|.. ..||.||..| |.||...|.|
rlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaealglpllpvvvdprlrErdfgalegltldeia

AKYGEAQVQIWRRSFDTPPPPMEPGHPYYenIVKDPRYAeGPKPEEFPQFESLKLTIERTLPYWNDVIIPQMKEGKRILIAAHGNSLRGIVKHLDNLSED
.|..|..|...|...|..||..|. ....  .. |.||| . ... .|  |||. ...| |....... ...|.||..|. .||...| ....| .|. .
ekfpeelvlwlrdpldvrppllelldell..llldlrya.lldedllpggEsladvaaRvlaaleellaralkpgknvlvVsHggvirallayllglple

AIMALNLPTGIPFVYELDENFKPVVSMQFLGD
.|. ||.|.| ..|.|||......  ...|.|
eilrlnipngsvtvlelddglvslndtshldd
0037864 Phosphoglycerate mutase-like 5-234 6.4e-60 194.3 In-house 8-209 (211) alignment 
Range on Protein: 5-234
Range on HMM: 8-209/211.0
YKIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASILKASGHKEIPIQKTWRLNERHYGGLTGLNKAET
.....|||||.|||... ..||.|..|.|.|.|.| |.|.|..|.||.||....| |.||. |.. ||.| |.  .|.. ..||.||..| | ||...|.
trlyLvRHGetewnaegrlqgwldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiilealglpllpvevdprlrErdfgalegltleei

AAKYGEAQVQIWRRSFDTPPPPMepghpyyenivkdpryaegpkpeefpqfESLKLTIERTLPYWNDVIIPQMKEGKRILIAAHGNSLRGIVKHLDNLSE
|.||.|..|...|...|..||..                            |||. ...| ||...... ...|.|...|. .||..|| ....| .|| 
aekypeelvawlrdpydfrppgg............................EsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllglsl

DAIMALNLPTGIPFVYELDENFKPVVSMQF
.... ||||.| ..|.|||.. ...||...
eellrlnlpngsvtvlelddggwvlvslnl
0035570 Phosphoglycerate mutase-like 6-229 2.9e-52 169.5 In-house 1-182 (219) alignment 
Range on Protein: 6-229
Range on HMM: 1-182/219.0
KIVMVRHGESEWNQKNQFCGwyDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASIlkasghkEIPIQKTWRLNERHYGGLTGLNKAETA
....|||||.||| .....|  |..|.|.|.|.| |.|.| .| |..||....| |.||. |.. |       ..|.. ..||.|...| | ||...|.|
rlyLvRHGetewnlegrlqg..dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii.......glpveidprLrEidfgdlegltldeia

AKYGEAQVQIWRRSFDTPPppmepghpyyenivkdpryaegpkpeefPQFESLKLTIERTLPYWNDViipqmKEGKRILIAAHGNSLRGIVKHLDNLSED
.||.|......|...|..|                            |. |||. ...| ||.....     ..|...|. .||...| ....| .|. .
ekypeelaawlrdpydyrp............................pggEsladvvaRvlpaleel.....edgenvlvVsHggvirallayllglple

AIMALNLPTGIPFVYELDENFKPV
.|. ||||.| . |.|||.. ...
eilrlnlpngsvtvleldggggkw
0039931 Phosphoglycerate mutase-like 6-236 9.7e-52 167.7 In-house 1-189 (219) alignment 
Range on Protein: 6-236
Range on HMM: 1-189/219.0
KIVMVRHGESEWNQKNQFCGwyDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASIlkasghkEIPIQKTWRLNERHYGGLTGLNKAETA
....|||||.||| .. ..|  |..|.|.|.|.| |.|.. || ||.||....| |.||. |.. |       ..|.. ..||.|...| | ||...|.|
rlyLvRHGetewnvegrlqg..dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii.......glpveidprLrEidfgdlegltleeia

AKYGEAQVQIWRRSFDTPPppmepghpyyenivkdpryaegpkpeefPQFESLKLTIERTLPYWNDViIPqmkeGKRILIAAHGNSLRGIVKHLDNLSED
.||.|......|...|..|                            |. |||. ...| ||..... ..    |...|. .||...| ....| .|| .
ekypeelaawlrdpydyrp............................pggEsladvvaRvlpaleel.la....genvlvVsHggvirallayllglsle

AIMALNLPTGIPFVYELDENFKPVVSMQFLG
.|. ||||.| . |.|||..   .|..   .
eilrlnlpngsvtvlelddggwvlvllnlts
0036887 Phosphoglycerate mutase-like 6-232 1.3e-50 164.1 In-house 3-195 (202) alignment 
Range on Protein: 6-232
Range on HMM: 3-195/202.0
KIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKdaGLEFDVAHTSVLTRAQVTLASILKASGhkeIPIQKTWRLNERHYGGLTGLNKAETA
....|||||.|||... ..|..|..|.|.|.|.| |.|....  || ||....| |.||. |.. |..| |   .|.. ..||.|...| | ||...|.|
rlyLvRHGetewnvegrlqgdldvpLtelGreqaralgerla..glpfdavysSpllRaiqTaeiiaealg...lpvivdprlrEidfgalegltleeia

AKYGEAQVQIWRRSFDTPPPPMepghpyyenivkdpryaegpkpeefpqfESLKLTIERTLPYWNDVIIPQmkEGKRILIAAHGNSLRGIVKHLDNLSED
.||.|......|...|..||..                            |||. ...| |....... ..  .|...|. .||..|| ....| .|| .
ekypeelaawlrdpydfrppgg............................EsladvvaRvlaaleellarl..dggnvlvVsHggvlrallayllglsle

AIMALN-LPTGIPFVYELDENFKPVVSM
... |. ||.| ..|.|||..   .|..
dllrlrklpngsvtvlelddggwvlvll
0053607 Phosphoglycerate mutase-like 6-232 1.1e-48 157.5 In-house 3-187 (191) alignment 
Range on Protein: 6-232
Range on HMM: 3-187/191.0
KIVMVRHGESEWNQKNQFCGwyDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASIlkasghkEIPIQKTWRLNERHYGGLTGLNKAETA
....|||||.||| .. ..|  |..|.|.|.|.| |.... .. ||.||....| |.||. |.. |       ..|.. ..||.|...| ..||...|.|
rlyLvRHGetewnaegrlqg..dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii.......glpvevdprlrEidfgdwegltleela

AKYGEAQVQIWRRSFDTPPppmepghpyyenivkdpryaegpkpeefPQFESLKLTIERTLPYWNDVIIpqmkeGKRILIAAHGNSLRGIVKHLDNLSED
.||.|......|...|..|                            |. |||. ...|.||......      |...|. |||...| ....| .|. .
ekypeelaawlrdpldyrp............................pggEsladvaaRvlpaleella.....ggnvlvVaHggvirallayllglple

AIMALNLPTGIPFVYELDENFKPVVSM
... ||||.| ..|.|||..   .|..
ellrlnlpngsvtvlelddggwvlvll
0050036 Phosphoglycerate mutase-like 6-224 2.2e-47 152.7 In-house 2-169 (171) alignment 
Range on Protein: 6-224
Range on HMM: 2-169/171.0
KIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVkdaglEFDVAHTSVLTRAQVTLASILkasghkeIPIQKTWRLNERHYGGLTGLNKAETA
....|||||.||| .. |.||.| .|.|.|...| |.|..      .||....| |.||. |.. ||       .|.....||.||..| ..||...|.|
rlyLvRHGetewnlegrfqgwtdvpLtelgraqaralgell.....pfdavysSpllRArqTaelil.......lpvivdprLrErdfGawegltldeia

AKYGEaqvqiwrrsfdtppppmepghpyyenivkdprYAEGPKPEEFPQFESLKLTIERTLPYWNDVIipqmkegKRILIAAHGNSLRGIVKHLDNLSED
|||.|                                .   .    .|. |||. ...| ||......       ...|..|||...| ....| .|| .
akype................................wlldlldlappggEsladvlaRvlpaleell.......gnvlvvaHggvirallalllglsle

AIMALNLPTGIPFVYELDE
.|. |.||.|...|.|||.
eilrlelpngsvlvleldd
His_Phos_1 Histidine phosphatase superfamily (branch 1) 6-193 9.1e-42 135.6 Pfam-A 1-156 (158) alignment 
Range on Protein: 6-193
Range on HMM: 1-156/158.0
KIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASILKasgHKEIPIQKTWRLNERHYGGLTGLNKAETA
....|||||||||......|| |. |.|||.|.| ..||. |.|.|..|.. || |.||. |....|.   ...|||.|..||.||..| . ||.|.|..
rlylvRHGesewnkegrlqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeille...eldipiikeprLrerdfgeweglpkeevk

AKYGEAQVQIWRRSFDTPPPpmepghpyyenivkdpryaegpkpeefpQFESLKLTIERTLPYWNDVIIpQMKEGKRILIAAHGNSLR
....|.. ...|....  ||                            . |||. ..||. |.....|  . ..|...|| .||..||
eefpeeyekwkrdkkefrpp............................egesladvyeRvapfleelie.akdkgenvlivsHggvlr
His_Phos_1 Histidine phosphatase superfamily (branch 1) 6-193 9.1e-42 135.6 In-house 1-156 (158) alignment 
Range on Protein: 6-193
Range on HMM: 1-156/158.0
KIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASILKasgHKEIPIQKTWRLNERHYGGLTGLNKAETA
....|||||||||......|| |. |.|||.|.| ..||. |.|.|..|.. || |.||. |....|.   ...|||.|..||.||..| . ||.|.|..
rlylvRHGesewnkegrlqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeille...eldipiikeprLrerdfgeweglpkeevk

AKYGEAQVQIWRRSFDTPPPpmepghpyyenivkdpryaegpkpeefpQFESLKLTIERTLPYWNDVIIpQMKEGKRILIAAHGNSLR
....|.. ...|....  ||                            . |||. ..||. |.....|  . ..|...|| .||..||
eefpeeyekwkrdkkefrpp............................egesladvyeRvapfleelie.akdkgenvlivsHggvlr
subfamily_TIGAR_pd Subfamily TIGAR 7-106 1.3e-21 69.3 In-house 3-101 (222) alignment 
Range on Protein: 7-106
Range on HMM: 3-101/222.0
IVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDagLEFDVAHTSVLTRAQVTLASILKASGHKEIP-IQKTWRLNERHYGGLTGLNKAETA
...|||||.|.|..... |  |  ||||| | |....| ...   ... . .| | ||. |   ||||.  |.   .... || || || . | ...|  
livVrhGetefnkekilqgqtdtpLsekGveQakrvakrLsn..ekinyifsSdllRAkqTaeiilkalkekkreaverdkrLrEreyGvyeGvaldelr

A
.
e
subfamily_PFKFB_pd Subfamily PFKFB 4-122 8.2e-14 43.5 In-house 6-115 (198) alignment 
Range on Protein: 4-122
Range on HMM: 6-115/198.0
KYKIVMVRHGESEWNQKNQFCGwyDANLSEKGQEEALAAGKAVKDAGLEfD-VAHTSVLTRAQVTLASIlkasghkEIPIQKTWRLNERHYGGLTGLNKA
...|..|||||||.|.|..  |  |..|.|.|.| | ...| .|.  |. .   .|| | |.. |   .       ..| ..   |.|.  | . ||.  
preiylvRhGeseknkkgrigg..dseLterGveyakklakfikeenlk.elrvwtselkrtiqTaell.......glpkeqwkaLdeldaGkcdgltye

ETAAKYGEAQVQIWRRSFDT
|.  |..|   .  . ..  
eikekfpeefkerkkdkyry
subfamily_PGAM5_pd Subfamily PGAM5 6-74 2.3e-07 22.1 In-house 3-66 (189) alignment 
Range on Protein: 6-74
Range on HMM: 3-66/189.0
KIVMVRHGESEWNQKNQfcgwyDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLASILKA
....||||. . .....     .  |.|.|.. |   || .|. .|.|.   .| ..||. |   |.| 
hlilvrhgqyvldddsd.....kkiltelGrrqaeltGkrlkelnlkftklvastmvravetadiiskq
subfamily_Dicty-HP1-1_pd Subfamily Dicty-HP1-1 6-68 1.3e-06 18.4 In-house 2-67 (210) alignment 
Range on Protein: 6-68
Range on HMM: 2-67/210.0
KIVMVRHGESEWNQK-NQFCGW--YDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTL
|. ..||||| .|.. |..     .|| |.|.|...|    . |..   . ..  .| ||||  | 
kvyiirhgestfnkaynekvdpylfdarlteegkkqanelsenvekllqdvelvisspltraldtt