Gene Pglym87 in Drosophila melanogaster

Synonym: CG17645, Dmel\CG17645, Pglym, pglym87, Dmel_CG17645, Pglym87

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily PGAM
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP107_AA protein Get Run
DmelP107_AA_41-289 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PGAM_pd Subfamily PGAM 42-290 4e-120 391.7 In-house 1-248 (248) alignment 
Range on Protein: 42-290
Range on HMM: 1-248/248.0
YRIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKSSEHKKIPVCTTWRLNERHYGGLTGLNKAET
...|..||||||.|..| ||||.||||||||..|| .||||||.|..|||...||||.|||.||.. |......||||..||||||||||.||||||||.
iklvllRhGeselnkenkfcgwvDakLsekGkeeAkkagkalkqanlefdivytSvlkRaqqTlevileeldqekiPvektwrLnErhyGaltglnkaev

AKKFGEEKVKIWRRSFDTPPPPMEKDHEYYACIVEDPRYKDqLKPEEFPKSESLKLTIERTLPYWNEVIVPQIKDGMRVLIAAHGNSLRGVVKHLECISD
|||.|||||||||||.|..|||.|.|.||...|..|.||.. ||.||.|.||||| ..||.||..||.|...||.|.||||.|||||.|...|.||.|||
akkyGeekvkiwRRsydvkPPpveedkeyfkeinkdrryee.lkeeelPesEslkevveRllpvlneeilkeikegkrvlivahgnsvrallkvlegisd

KDIMSLNLPTGIPFVYELDESLKPLATLKFLGDPETVKKAMESVANQGK
..|..|.||||||.||||||.|||... .||||.|.||||.|.||||||
eaikeldlptgiplvyeldenlkpvkkkqflgDeesvkkaaeavanqgk
0043909 Phosphoglycerate mutase-like 42-282 1.2e-72 236.5 In-house 3-244 (249) alignment 
Range on Protein: 42-282
Range on HMM: 3-244/249.0
YRIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKSSEHKKIPVCTTWRLNERHYGGLTGLNKAET
.|...|||||.|||....|.||.|. |.|.| ..| |.|.|||...| ||....| |.||..|....|.  .. |.|| ...||.||..| |.||.|||.
krlyLvRHGetewnaegrfqgwlDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileelgldklpvevdprLrErdfGalegltkaei

AKKFGEEKVKIWRRSFDTPPPPMEKDHEYYACIVEDPRYKD-QLKPEEFPKSESLKLTIERTLPYWNEVIVPQIKDGMRVLIAAHGNSLRGVVKHLECIS
|.|..|| |...|||.|..||..|...|... .. |....|  .    .|. |||. ...| ||...|.. ...||| .||| |||..|| ....|  .|
aekypeelvawlrrsydvlpplleeldelllellldyaladldplldrppggEsladvvaRvlpaleellarllkdggnvliVaHggvlrallayllgls

DKDIMSLNLPTGIPFVYELDESLKPLATLKFLGDPETVKKAM
. ||..||||.|...|.|||...||. .|..|.| . ... .
ledilrlnlpngsitvlelddggkpvvvlvllndtshleall
0036777 Phosphoglycerate mutase-like 42-289 4.6e-70 228.2 In-house 3-246 (247) alignment 
Range on Protein: 42-289
Range on HMM: 3-246/247.0
YRIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKSSEHKKIPVCTTWRLNERHYGGLTGLNKAET
.|...|||||.|||. ..|.||.|. |.|.| ..| |.|..||.... ||....| |.||..|....|.  .. ..|| ...||.||.|| |.||.|||.
krlyLvRHGetewnaegrfqgwlDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiilealglsllpvvvdprLrErdyGalegltkaei

AKKFGEEKVKIWRRSFDTPPPPMEKDHEYYaciVEDPRYKDQLKPEEFPKSESLKLTIERTLPYWNEVIVPQIKDGMRVLIAAHGNSLRGVVKHLECISD
|.|..|| |..||...|..||..|...|..     | ..   |.  ..|  |||. ...| ||...|.. ...||| .||. .||..|| ....|. .|.
aekypeelvawwrdpydyrppllelllell...lldllryallpldllpggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllglsl

KDIMSLNLPTGIPFVYELDESLKpLATLKFLGDPETVKKAMESVANQG
 ||..||||.|...|.|||.. | | .|..|.|.. .....| ||..|
edilrlnlpngsitvleldddgk.lwvleslndtshlelgleavadfg
0049178 Phosphoglycerate mutase-like 42-269 2e-64 209.7 In-house 4-226 (243) alignment 
Range on Protein: 42-269
Range on HMM: 4-226/243.0
YRIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKSSEHKKIPVCTTWRLNERHYGGLTGLNKAET
.|...|||||.|||......||.|. |.|.|...| |.|..|..... ||....| |.||..|....|.   ....|| ...||.||..| |.||.|||.
trlyLvRHGetewnaegrlqgwtDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiilealglpllpvvvdprLrErdfGalegltkaei

AKKFGEEKVKIWRRSFDTPPPPMEKDHEYYACIveDPRYKDQLKpeeFPKSESLKLTIERTLPYWNEVIVPQIKDGMRVLIAAHGNSLRGVVKHLECISD
|.|..|| |..||...|..||... ...... .  |....|      .|  |||. ...| ||...|.. ....|| .||. |||...| ....|  ...
aakypeelvawwrdpydarppalllldlllpll..drlladldl...lpggEsladvaaRvlpaleellaellhdgktvlvVaHggvirallalllglpl

KDIMSLNLPTGIPFVYELDESLKPLATL
.....||||.| ..|.|||...  | .|
eellrlnlpngsvtvlelddggwvlvsl
0051064 Phosphoglycerate mutase-like 42-281 1.8e-61 200.3 In-house 4-239 (241) alignment 
Range on Protein: 42-281
Range on HMM: 4-239/241.0
YRIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKSSEHKKIPVCTTWRLNERHYGGLTGLNKAET
.|...|||||||||  ....||.|. |.|.|...| |.|..|.|. | ||....| |.||..|......   ....|| ...||.|...| |.||...|.
krlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaealglpllpvvvdprlrEidfgalegltleei

AKKFGEEKVKIWRRSFDTPPPPMEKDHEYYacIVEDPRYKDqLKPEEFPKSESLKLTIERTLPYWNEVIVPQIKDGMRVLIAAHGNSLRGVVKHLECISD
|.||.|| |...|...|..||..| .....  .. |.||.. |... .|  |||. ...| ||...|.. ....|| .||. .||...| ....|  ...
aekfpeelvawlrdpldvrppllelldlll..llldlryag.llddllpggEsladvaaRvlpaleellarllldgknvlvVsHggvirallayllglpl

KDIMSLNLPTGIPFVYELDESLKpLATLKFLGDPETVKKA
.....||||.| ..|.|||...|   .|..|.|.......
eellrlnlpngsvtvleldddgk.rvvlvllndtshledl
0048955 Phosphoglycerate mutase-like 43-275 6e-61 198.5 In-house 2-231 (240) alignment 
Range on Protein: 43-275
Range on HMM: 2-231/240.0
RIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKSSEHKKIPVCTTWRLNERHYGGLTGLNKAETA
|...||||||||| .....||.|. |.|.|...| |.|..|.|. | ||....| |.||..|......   ....||....||.||..| |.||...|.|
rlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaealglpllpvvvdprlrErdfgalegltldeia

KKFGEEKVKIWRRSFDTPPPPMEKDHEYYacIVEDPRYKdQLKPEEFPKSESLKLTIERTLPYWNEVIVPQIKDGMRVLIAAHGNSLRGVVKHLECISDK
.||.|| |...|...|..||..| ..|..  .. |.||.  |... .|  |||. ...| |....|.. ...|.| .||. .||...| ....|  ....
ekfpeelvlwlrdpldvrppllelldell..llldlrya.lldedllpggEsladvaaRvlaaleellaralkpgknvlvVsHggvirallayllglple

DIMSLNLPTGIPFVYELDESLKPLATLKFLGDP
.|..||.|.| ..|.|||..|..|    .|.|.
eilrlnipngsvtvlelddglvslndtshlddl
0037864 Phosphoglycerate mutase-like 42-269 1.6e-57 186.5 In-house 8-207 (211) alignment 
Range on Protein: 42-269
Range on HMM: 8-207/211.0
YRIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKSSEHKKIPVCTTWRLNERHYGGLTGLNKAET
.|...|||||.|||......||.|. |.|.|...| |.|.||.|....||....| |.||..|....|.   . ..|| ...||.||..| | ||...|.
trlyLvRHGetewnaegrlqgwldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiilealglpllpvevdprlrErdfgalegltleei

AKKFGEEKVKIWRRSFDTPPPPMekdheyyacivedprykdqlkpeefpksESLKLTIERTLPYWNEVIVPQIKDGMRVLIAAHGNSLRGVVKHLECISD
|.|..|| |...|...|..||..                            |||. ...| ||...|.. ...||| .||. .||..|| ....|  .|.
aekypeelvawlrdpydfrppgg............................EsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllglsl

KDIMSLNLPTGIPFVYELDESLKPLATL
 ....||||.| ..|.|||.....| .|
eellrlnlpngsvtvlelddggwvlvsl
0035570 Phosphoglycerate mutase-like 43-264 2.4e-51 166.5 In-house 1-180 (219) alignment 
Range on Protein: 43-264
Range on HMM: 1-180/219.0
RIVMVRHGESEWNQKNLFCGwfDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAAlkssehkKIPVCTTWRLNERHYGGLTGLNKAETA
|...|||||.||| .....|  |. |.|.|...| |.|.||.| .|.||....| |.||..|....       ..||....||.|...| | ||...|.|
rlyLvRHGetewnlegrlqg..dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii.......glpveidprLrEidfgdlegltldeia

KKFGEEKVKIWRRSFDTPPppmekdheyyacivedprykdqlkpeefPKSESLKLTIERTLPYWNEVivpqiKDGMRVLIAAHGNSLRGVVKHLECISDK
.|..|| ....|...|..|                            |. |||. ...| ||...|.     .|| .||. .||...| ....|  ... 
ekypeelaawlrdpydyrp............................pggEsladvvaRvlpaleel.....edgenvlvVsHggvirallayllglple

DIMSLNLPTGIPFVYELDESLK
.|..||||.| . |.|||.. .
eilrlnlpngsvtvleldgggg
0039931 Phosphoglycerate mutase-like 43-273 9.1e-51 164.6 In-house 1-189 (219) alignment 
Range on Protein: 43-273
Range on HMM: 1-189/219.0
RIVMVRHGESEWNQKNLFCGwfDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAAlkssehkKIPVCTTWRLNERHYGGLTGLNKAETA
|...|||||.||| .....|  |. |.|.|...| |.|..||| ...||....| |.||..|....       ..||....||.|...| | ||...|.|
rlyLvRHGetewnvegrlqg..dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii.......glpveidprLrEidfgdlegltleeia

KKFGEEKVKIWRRSFDTPPppmekdheyyacivedprykdqlkpeefPKSESLKLTIERTLPYWNEViVPqikdGMRVLIAAHGNSLRGVVKHLECISDK
.|..|| ....|...|..|                            |. |||. ...| ||...|. ..    | .||. .||...| ....|  .|. 
ekypeelaawlrdpydyrp............................pggEsladvvaRvlpaleel.la....genvlvVsHggvirallayllglsle

DIMSLNLPTGIPFVYELDESLKPLATLKFLG
.|..||||.| . |.|||.    | .|   .
eilrlnlpngsvtvlelddggwvlvllnlts
0036887 Phosphoglycerate mutase-like 42-266 4.5e-49 159.0 In-house 2-192 (202) alignment 
Range on Protein: 42-266
Range on HMM: 2-192/202.0
YRIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKdaKIEFDVAHTSVLTRAQETLRAALKSSEhkkIPVCTTWRLNERHYGGLTGLNKAET
.|...|||||.|||......|..|. |.|.|...| |.|..|.  .. ||....| |.||..|......  .   .||....||.|...| | ||...|.
trlyLvRHGetewnvegrlqgdldvpLtelGreqaralgerla..glpfdavysSpllRaiqTaeiiaealg...lpvivdprlrEidfgalegltleei

AKKFGEEKVKIWRRSFDTPPPPMekdheyyacivedprykdqlkpeefpksESLKLTIERTLPYWNEVIVPQikDGMRVLIAAHGNSLRGVVKHLECISD
|.|..|| ....|...|..||..                            |||. ...| |....|.. ..  || .||. .||..|| ....|  .|.
aekypeelaawlrdpydfrppgg............................EsladvvaRvlaaleellarl..dggnvlvVsHggvlrallayllglsl

KDIMSLN-LPTGIPFVYELDESLKPL
 |...|. ||.| ..|.|||..   |
edllrlrklpngsvtvlelddggwvl
0053607 Phosphoglycerate mutase-like 43-265 5.1e-47 152.1 In-house 3-183 (191) alignment 
Range on Protein: 43-265
Range on HMM: 3-183/191.0
RIVMVRHGESEWNQKNLFCGwfDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAAlkssehkKIPVCTTWRLNERHYGGLTGLNKAETA
|...|||||.||| .....|  |. |.|.|...| |....|..  ..||....| |.||..|....       ..|| ...||.|...| ..||...|.|
rlyLvRHGetewnaegrlqg..dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii.......glpvevdprlrEidfgdwegltleela

KKFGEEKVKIWRRSFDTPPppmekdheyyacivedprykdqlkpeefPKSESLKLTIERTLPYWNEVIVpqikdGMRVLIAAHGNSLRGVVKHLECISDK
.|..|| ....|...|..|                            |. |||. ...|.||...|..      | .||. |||...| ....|  ... 
ekypeelaawlrdpldyrp............................pggEsladvaaRvlpaleella.....ggnvlvVaHggvirallayllglple

DIMSLNLPTGIPFVYELDESLKP
... ||||.| ..|.|||..   
ellrlnlpngsvtvlelddggwv
0050036 Phosphoglycerate mutase-like 43-261 1.3e-45 147.0 In-house 2-169 (171) alignment 
Range on Protein: 43-261
Range on HMM: 2-169/171.0
RIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALkdakiEFDVAHTSVLTRAQETLRAALkssehkkIPVCTTWRLNERHYGGLTGLNKAETA
|...|||||.||| ...|.|| |  |.|.|...| |.|..|     .||....| |.||..|....|       .|| ...||.||..| ..||...|.|
rlyLvRHGetewnlegrfqgwtdvpLtelgraqaralgell.....pfdavysSpllRArqTaelil.......lpvivdprLrErdfGawegltldeia

KKFGEekvkiwrrsfdtppppmekdheyyacivedprYKDQLKPEEFPKSESLKLTIERTLPYWNEVIvpqikdgMRVLIAAHGNSLRGVVKHLECISDK
.|..|                                .   |    .|  |||. ...| ||...|..        .||..|||...| ....|  .|..
akype................................wlldlldlappggEsladvlaRvlpaleell.......gnvlvvaHggvirallalllglsle

DIMSLNLPTGIPFVYELDE
.|..|.||.|...|.|||.
eilrlelpngsvlvleldd
His_Phos_1 Histidine phosphatase superfamily (branch 1) 43-230 2.9e-43 140.5 Pfam-A 1-156 (158) alignment 
Range on Protein: 43-230
Range on HMM: 1-156/158.0
RIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKsseHKKIPVCTTWRLNERHYGGLTGLNKAETA
|...|||||||||... ..|| |..|.|||...| ..||.||.|....|.. || |.||..|... |.   ...||.....||.||..| . ||.|.|..
rlylvRHGesewnkegrlqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeille...eldipiikeprLrerdfgeweglpkeevk

KKFGEEKVKIWRRSFDTPPPpmekdheyyacivedprykdqlkpeefpKSESLKLTIERTLPYWNEVIVpQIKDGMRVLIAAHGNSLR
..|.||. |..|....  ||                            . |||. ..||. |...|.|  . ..| .||| .||..||
eefpeeyekwkrdkkefrpp............................egesladvyeRvapfleelie.akdkgenvlivsHggvlr
His_Phos_1 Histidine phosphatase superfamily (branch 1) 43-230 2.9e-43 140.5 In-house 1-156 (158) alignment 
Range on Protein: 43-230
Range on HMM: 1-156/158.0
RIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKsseHKKIPVCTTWRLNERHYGGLTGLNKAETA
|...|||||||||... ..|| |..|.|||...| ..||.||.|....|.. || |.||..|... |.   ...||.....||.||..| . ||.|.|..
rlylvRHGesewnkegrlqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeille...eldipiikeprLrerdfgeweglpkeevk

KKFGEEKVKIWRRSFDTPPPpmekdheyyacivedprykdqlkpeefpKSESLKLTIERTLPYWNEVIVpQIKDGMRVLIAAHGNSLR
..|.||. |..|....  ||                            . |||. ..||. |...|.|  . ..| .||| .||..||
eefpeeyekwkrdkkefrpp............................egesladvyeRvapfleelie.akdkgenvlivsHggvlr
subfamily_TIGAR_pd Subfamily TIGAR 43-143 3.6e-22 71.1 In-house 2-101 (222) alignment 
Range on Protein: 43-143
Range on HMM: 2-101/222.0
RIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEfdVAHTSVLTRAQETLRAALKSSEHKKI-PVCTTWRLNERHYGGLTGLNKAET
....|||||.|.|..... |  |  ||||| . | ...| |...||.   . .| | ||..|  . ||... ||  .|  . || || || . | ...| 
ilivVrhGetefnkekilqgqtdtpLsekGveQakrvakrLsnekin..yifsSdllRAkqTaeiilkalkekkreaverdkrLrEreyGvyeGvaldel

AK
 .
re
subfamily_PFKFB_pd Subfamily PFKFB 41-161 3.6e-14 44.7 In-house 6-117 (198) alignment 
Range on Protein: 41-161
Range on HMM: 6-117/198.0
KYRIVMVRHGESEWNQKNLFCGwfDAKLSEKGQQEACAAGKALKDAKIEfD-VAHTSVLTRAQETLRAAlkssehkK-------IpvcttwrLNERHYGG
.. |..|||||||.|.|.   |  |..|.|.|.. | ...| .|. ... .   .|| | |...| ..        .       .       |.|.  | 
preiylvRhGeseknkkgrigg..dseLterGveyakklakfikeenlk.elrvwtselkrtiqTaell.......glpkeqwka.......LdeldaGk

LTGLNKAETAKKFGEEKVKIWRRSFDTPP
. ||.  |. .||.||  .  . ..   .
cdgltyeeikekfpeefkerkkdkyryry
subfamily_PGAM5_pd Subfamily PGAM5 43-116 5.4e-08 24.2 In-house 3-71 (189) alignment 
Range on Protein: 43-116
Range on HMM: 3-71/189.0
RIVMVRHGESEWNQKNlfcgwFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKSSEHKK
....||||. . ....      .  |.|.|.. |   || ||. ...|.   .| ..||.||    .|  ....
hlilvrhgqyvlddds.....dkkiltelGrrqaeltGkrlkelnlkftklvastmvravetadiiskqlpdvp
subfamily_STS_pd Subfamily STS 64-236 2.1e-07 22.6 In-house 51-197 (245) alignment 
Range on Protein: 64-236
Range on HMM: 51-197/245.0
FDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALKSSEhKKIPVCTTWRLNerhyggltglnkaetakkfgeEKVKIWRRSFDTPPPP
.|  |.| |.. |   |.|| .|.|. ...  |  .|  .|  | ||. . |||...    |                      | .|. |..  ....|
sDpPlterGviqAkllgraLleagikiehifcSPslrciqTaaailkglg.kkikikvepgll.....................ewlkldrkpipellsp

MEKDHEYYAcIveDPRYKDQLKPEEFPKSESLKLTIERTLPYWNEVIVPQiKDGMRVLIAAHGNSLRGVVKHL
 |  . ..  |  |. ||  |...|. ..|| .  .||.   ..|.|    ..   .|| ||. .|  . . |
eelkkffpq.i..dedYkpvlslselkskeseeelyeRikkvvkeiiekv.pedgniliVahaatldalsrql
subfamily_Dicty-HP1-1_pd Subfamily Dicty-HP1-1 43-110 2.6e-07 20.7 In-house 2-72 (210) alignment 
Range on Protein: 43-110
Range on HMM: 2-72/210.0
RIVMVRHGESEWNQK-NLF--CGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLRAALK
.. ..||||| .|.. | .     |||.|.|.|...|    . ...   . ..  .| |||| .| . || 
kvyiirhgestfnkaynekvdpylfdarlteegkkqanelsenvekllqdvelvisspltraldttkiall