Gene Pgam5 in Drosophila melanogaster

Synonym: CG14816, DPGAM5, Dmel\CG14816, EG:63B12.4, PGAM5, dPGAM5, Dmel_CG14816, Pgam5

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily PGAM5
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP108_AA protein Get Run
DmelP108_AA_85-278 phosphatase_domain Get Run
Domains
Summary
100200MRKLTSFVCGTGAGLAAYYLQRLRDPQTVVQNSWTHSDKPVDPWALWDTNWDCREPRALVRPLRNSQPEEENRYNAELEKAKAKKARHIILVRHGEYLDVGDSDDTHHLTERGRKQAEFTGKRLCELGIKWDKVVASTMVRAQETSDIILKQIDFEKEKVVNCAFLREGAPIPPQPPVGHWKPEASQFLRDGSRIEAGFRRYFHRAYPDQEKESYTLIVGHGNVIRYFVCRALQFPAEGWLRININHASITWLTISPSGNVSIKYLGDSGFMPAELLTNRIPRDVKNVVHP1Curated phosphatase domainHis_Phos_1Pfam Domainsubfamily_PGAM5_pd(1)0043909(2)0036777(3)0051064(4)0048955(5)Subfamily
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PGAM5_pd Subfamily PGAM5 87-275 4.9e-102 330.9 In-house 2-188 (189) alignment
0043909 Phosphoglycerate mutase-like 87-274 3.8e-38 123.7 In-house 3-242 (249) alignment
0036777 Phosphoglycerate mutase-like 87-274 1.3e-37 122.1 In-house 3-237 (247) alignment
0051064 Phosphoglycerate mutase-like 87-273 9.5e-37 119.6 In-house 4-237 (241) alignment
0048955 Phosphoglycerate mutase-like 89-272 3.8e-34 111.0 In-house 3-228 (240) alignment
0037864 Phosphoglycerate mutase-like 86-265 4.3e-34 110.1 In-house 7-206 (211) alignment
0039931 Phosphoglycerate mutase-like 88-278 1.2e-33 108.8 In-house 1-197 (219) alignment
0035570 Phosphoglycerate mutase-like 89-276 1.2e-33 108.8 In-house 2-197 (219) alignment
0049178 Phosphoglycerate mutase-like 87-272 2.4e-33 108.1 In-house 4-232 (243) alignment
0036887 Phosphoglycerate mutase-like 87-271 4.1e-31 100.5 In-house 2-200 (202) alignment
0053607 Phosphoglycerate mutase-like 87-261 9e-30 96.0 In-house 2-183 (191) alignment
0050036 Phosphoglycerate mutase-like 89-257 3.2e-22 71.1 In-house 3-169 (171) alignment
His_Phos_1 Histidine phosphatase superfamily (branch 1) 88-228 3.7e-21 68.7 Pfam-A 1-158 (158) alignment
His_Phos_1 Histidine phosphatase superfamily (branch 1) 88-228 3.7e-21 68.7 In-house 1-158 (158) alignment
subfamily_TIGAR_pd Subfamily TIGAR 89-168 2.8e-12 38.8 In-house 3-85 (222) alignment
subfamily_PGAM_pd Subfamily PGAM 89-162 4.4e-10 31.3 In-house 3-80 (248) alignment
subfamily_STS_pd Subfamily STS 103-158 1.1e-09 30.0 In-house 51-103 (245) alignment
subfamily_PFKFB_pd Subfamily PFKFB 85-156 2.1e-06 19.3 In-house 5-76 (198) alignment
subfamily_Cele-STS-like_pd Subfamily Cele-STS-like 109-154 5e-06 17.0 In-house 52-97 (229) alignment
0053031 Phosphoglycerate mutase-like 88-153 5.7e-06 19.0 In-house 6-91 (342) alignment