Gene PHPT1 in Homo sapiens

Synonym: CGI-202, HEL-S-132P, HSPC141, PHP14, RP11-216L13.10-005, PHPT1

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PHP
Superfamily PHP
Family PHP
Subfamily PHP
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP167_AA protein Get Run
HsapP167_AA_4-127 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
PHP 5-127 2.4e-62 198.3 In-house 2-121 (121) alignment 
Range on Protein: 5-127
Range on HMM: 2-121/121.0
DLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAeSKEIVRGYKWAEYHgeADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQH
.|| .||||||..||||||||||.|..|. ..|| |||.||||..||||  |||||.||....|||.|.||||||||.|.|..|||.|||||..|| |.|
elakvpdvdidpeGvfkyvlirvtskerkdgaaa.skevvrGyaraeyh..adiydrvsselekqgldaeclGGGriehdseekkikvyGysvgyGkadh

AISTEKIKAKYPDYEVTWANDGY
|...||.|.||||||.|....||
avtkeklktkyPdyeitlsdeGy
subfamily_PHP_pd Subfamily PHP 7-125 9.9e-49 154.0 In-house 2-114 (114) alignment 
Range on Protein: 7-125
Range on HMM: 2-114/114.0
ALIPDVDIDSDGVFKYVLIRVhsapRSGAPAAESKEIVRGYKWAEYHgeADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQHAI
| .|.|||||.|.||||||..    .. . ...||.|||||..||||  ||||..|. ...|.|....|||||||.|....|||.|||||...| |.|.|
aavpevdidskGkfkYvliel....ttdsegkksktivrgyskaeyh..adiyeevkeeleklglkakclGGGriehdkekkkikvyGyskgfGkadhei

STEKIKAKYPDYEVTWAND
..|..|.|||||..|..|.
akeilktkypdykitisne
0053050 PHP14-like 5-123 3.8e-48 151.4 In-house 1-117 (118) alignment 
Range on Protein: 5-123
Range on HMM: 1-117/118.0
DLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHGeaDIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQH
.|| .|.||||..||||||||.|.  .. . .  ||| ||||.|.||||   |||..||....|.|.|.||||||||.|.|..|||.|||||...|.|.|
slakvpevdideeGvfkYvlikvtlkgltdsggkesklivrglkkaeyHa..diyeevskeleklgldleclGGGriehdsekkkikvyGyslgfGkadh

AISTEKIKAKYPDYEVTWA
.|..|..| ||||||.|..
eialeilktkypdyeitls
Ocnus Janus/Ocnus family (Ocnus) 6-120 1.2e-43 137.3 Pfam-A 1-108 (108) alignment 
Range on Protein: 6-120
Range on HMM: 1-108/108.0
LALIPDVDIDSDGVFKYVLIRVHSAPrsgapAAESKEIVRGYKWAEYHGeaDIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQHA
|| .|.||||..|.||||||.|..       . ||||.|||.|.||||   |||.||. ...|.|...||||||||.|....|||.|||||...| |.|.
LakvpevdideeGkfkYvlikvkike.....kdeskevvrglkkaeyHa..diyekvkkeleklgleteclGGGriehdeekkkikvyGyskgfGkadhe

ISTEKIKAKYPDYEV
|..|..|.||.|||.
iakeilkkkykdyei
Ocnus Janus/Ocnus family (Ocnus) 6-120 1.2e-43 137.3 In-house 1-108 (108) alignment 
Range on Protein: 6-120
Range on HMM: 1-108/108.0
LALIPDVDIDSDGVFKYVLIRVHSAPrsgapAAESKEIVRGYKWAEYHGeaDIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQHA
|| .|.||||..|.||||||.|..       . ||||.|||.|.||||   |||.||. ...|.|...||||||||.|....|||.|||||...| |.|.
LakvpevdideeGkfkYvlikvkike.....kdeskevvrglkkaeyHa..diyekvkkeleklgleteclGGGriehdeekkkikvyGyskgfGkadhe

ISTEKIKAKYPDYEV
|..|..|.||.|||.
iakeilkkkykdyei