Gene PP2D1 in Homo sapiens

Synonym: C3orf48, PP2D1

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PP2D1
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP173_AA protein Get Run
HsapP173_AA_164-623 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PP2D1_pd Subfamily PP2D1 169-624 1.1e-216 713.3 In-house 1-492 (492) alignment
Range on Protein: 169-624
Range on HMM: 1-492/492.0
KGVGICEDRNSTWKADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQMTTDEQQIINSFYTVFREEYAAIEDLFSA
|.||||||.||.||..|.||.|....|||..|.||||..||..||.|||....||...||..|.|.|.....||....|.|...|....|.|...|...|
kavGiCedknsrWKskmeDkrtlqdyfgndvnscFfgiyDGynGataAeiaakelhevlleelekvdervslttavnlidnndltdyelerasrsdsira

INKTEAVRCEYEDTHKAFAKAFWRMDRLLGLGRKEVSRVQWSGCSAVTCILEGKPKSPYAHKNWKRKNTHDGLAESSPSQEMPKIISGILHVANTGNVQA
|.|.|.|..|.|...|||.|...|.||||..|..|.|||.||||||.|..|||......|......|....||...|...|......|.|..||.|||||
ilkeesvkpefekvkkAfrksylrldrlLsygieeesrvrWsGCsAltllleGnkreteatekeekkdseeGlekesngsevhleelgvlyianaGnvqA

VLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEPYGLVEGQVKTTRGLGFHGNLKLKKSIIPAPQTISVPIDDLCQFLIVATNGLWEVLDKEEVTA
||||.||...||.|||.||..||.|. ..|.|....|..|||.|...||||||..|..|||||.||.|.|.||..|. .|||..|.|||||||..|||..
vLcreGkaiiLtreHtprnkkERtRvekagsvvvkseknglvnGildttRGLGnyGdpkLkksvipePkttsvkldeaaqflvlAsnGlWevlseeevls

LAMTTFHMYK----------------------ETYCPIIPNKSPSKGPLLFSTSEPNLTKSQ---SNIHVLFQYKSVSEVRVSTTNSKENLSDSNYSKYC
|...|...||                      |.............|.  |.|||..|....   ||...||.|...|||........|.||..|..|..
LvkqtlaiyksrvraenvpdsdvttvgedylgEleakklsaryentgfdkfvtseidldaaegdesnlqklfsynelsevkedaddereglseanskkei

IYNPENVETFPAETTHRKPCSEKVTDRPTSVNDVATN---EKESDTKSF--------YEGAAEYVSHELVNAALLAGSRDNITVMVIFLNGS
.||.|.......|....|...||.|.|...|..||.|   |||..|||.        ||.|||..|..||..|||||||||||||||.|.|.
tyneedtdksaeeskeaksseekstnrsirveevaenvkaekeeetksdgivdkkekyelaAealserlvqsALlAGsrDnitvmvilLkGc

0034914 PP2C-like 165-623 2.5e-52 170.5 In-house 17-292 (295) alignment
Range on Protein: 165-623
Range on HMM: 17-292/295.0
HLLIKGVGICEDRNStwKADMNDKFTVVSNFGN-KPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQMTtdeqqiinsfytvfreeyaaie
.||.  ||.. |..   .  . | ..|| |. .  .....||.|||| | .|||. |  |. |||..| |.. .....                      
lllllrvgvasdqGr..rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltls......................

dlfsainkteavrceYEDTHKAFAKAFWRMDRLLGLGRKEVSRVQWSGCSAVTCILEGKpkspyahknwkrknthdglaesspsqempkiisgILHVANT
               .|| ..|. |||...|. |     . .....||..||.... |.                                   |.|||.
...............ledieealrkaflaadeellelallrpelagsGtTavvalirgn..................................klyvanv

GNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSnepyGLVEGQVKTTRGLGFHGNLK------LKKSIIPAPQTISVPID-DLCQFLIVATNG
|. .|||.|||.  .||..|.  |  ||.|||..| ..|     | | |.   || ||..  ..      |.  ... |........ . ..||..|. |
GDSravllrngelvqltvdhkpvnelererilsaggavsh....grvngvlavtRalGdfdlklllslllleplvsaePdvtvleltledddfllLasDG

LWEVLDKEEVTALAMTTFHMYKEtycpiipnkspskgpllfstsepnltksqsnihvlfqyksvsevrvsttnskenlsdsnyskyciynpenvetfpae
||.||. ||. ........ ...                                                                             
lwdvlsneeivdivrsllakgld.............................................................................

tthrkpcsekvtdrptsvndvatnekesdtksfyegaAEYVSHELVNAALLAGSRDNITVMVIFLNG
                                     .|....|||..|| .||||||||.|..|||
.....................................leeaaeeLvdlAlargsrDNiTvvvvrlng

subfamily_PPM1A_pd Subfamily PPM1A 176-622 6.3e-39 127.0 In-house 17-281 (282) alignment
Range on Protein: 176-622
Range on HMM: 17-281/282.0
DRNSTWKADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHqlskfdpsyqmttdeqqiinsfytvfreeyaaiE----Dlfsaink
. .. |...| |..||| ..|. ..  || .|||| |...|. .. .|.  .|.                                 |    .       
ssmqgwrvemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenile.................................eeelke.......

TEAVRCEYEDTHKAFAKAFWRMDRLLGLGRKEVSRVQWSGCSAVTCILEgkpkspyahknwkrknthdglaesspsqempkiiSGILHVANTGNVQAVLC
... . | .....|. ..| ..|  .    ....  . ||. |||....                                     | .|| |   ||||
aaleasekdevkealrqgfLaldeairelstdlktadksGsTavtvlvs..................................ekhliianlGDsRavlc

RNGKGFCLTKEHTTRNTNERRRILQNGAVISsnepYGLVEGQVKTTRGLGFHGNLK------LKKSIIPAPQTISVPIDDLCQFLIVATNGLWEVLDKEE
||||   ||..|   ...|..|| | |  .      . |.|.   .| || .   .       .. ... |.. |. ...  .||..|  |.|.||. ||
rngkaaflteDHkpsrpkEkkRieqAGGsvv....vsRvnGaLAvsRalGDyeykeeeekkaeeqlvsaepevtsierseeddflvlacDGiwDvlsdee

VTALAMTTFHMYKETYCPiipnkspskgpllfstsepnltksqsnihvlfqyksvsevrvsttnskenlsdsnyskyciynpenvetfpaetthrkpcse
|..|. ..... .|                                                                                      
vvelvrkrlevadeleev..................................................................................

kvtdrptsvndvatnekesdtksfyegaaeyvSHELVNAALLAGSRDNITVMVIFLN
                                ...||. || .|||||..|.|....
................................akalvdkalekgsrDNlsvlvvlfa

PP2Cc_SM00332 177-473 7.5e-39 126.7 In-house 16-239 (274) alignment
Range on Protein: 177-473
Range on HMM: 16-239/274.0
RNSTWKADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYqmttdeqqiinsfytvfreeyaaiedlfsainkteavr
 . .|.  |.| . || .. .. .. |||.|||| |...|...| .||  |  .|.| .  .                                      
smqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel......................................

ceYEDTHKAFAKAFWRMDRLLGLG-RKEVSRVQWSGCSAVTCILEGKPkspyahknwkrknthdglaesspsqempkiisgiLHVANTGNVQAVLCRNGK
  ..|. .| .||| ..|  .    ...  . . ||..||...| ..                                   |.|||.|  .||||||||
..eddveealkkaflstdeeileeeqskelenalsGstavvallkked..................................lyvanvGDSravlcrngk

GFCLTKEHTTRNTNERRRILQNGAVISSNepygLVEGQVKTTRGLGFHGNL----KLKKSIIPAPQTISVPIDDLCQFLIVATNGLWEVLDKEEVTALAM
   |...|.. . .||.|| ..|.|.. .     | |. . .| .| |       . .. |.. |..  | ...  .|||.|. |||.||...||  . .
avqlsvdhkpedederkRikkaggvvekg....rvngglavsrafGdhflkknkklkepyitaepdvkvvtltsedeflilaSDGlwdvlsnqevvdivr

TT
 .
kl

0049733 PP2C-like 182-622 2.7e-30 98.5 In-house 15-234 (235) alignment
Range on Protein: 182-622
Range on HMM: 15-234/235.0
KADMNDKFTVvsnfgnkpNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYqmttdeqqiinsfytvfreeyaaiedlfsainkteavrceyed
.  . | . |        .. .|...||| |. |.|. |  |. .||..| ....                                             
rkvneDavlv........glllfavaDGhgghaagevasellvetllelllelllld...........................................

THKAFAKAFWRMDRLLGLGRKEVSRVQWSGCSAVTCILEGKPkspyahknwkrknthdglaesspsqempkiisgiLHVANTGNVQAVLCRNGKGFCLTK
. .|. |||..... |    ..   ....|..||...| |.                                   |.||| |.  |.|.|.||  .||.
leealrkaflaaneallelalaspelagmgtTavvalldggk..................................lyvanvGDsrayllrdgklvqlte

EHTTRNTNERRRILQNGAVIssnepygLVEGQVKTTRGLGfHGNLKlkksiipaPQTISVPIDDLCqFLIVATNGLWEVLDKEEVTALAMTtFHMykety
.|.  |  ||.||.. | ..        | |.   || || .  ||        |.. ...... . ||..|. |||.||. ||. .| ..  ..     
dhspvnelerqriitaggav.......rvpgrlaltralG.dlllk........pdvtvlelepgd.flllasDGlwdvlsdeeivdllrs.ldl.....

cpiipnkspskgpllfstsepnltksqsnihvlfqyksvsevrvsttnskenlsdsnyskyciynpenvetfpaetthrkpcsekvtdrptsvndvatne
                                                                                                    
....................................................................................................

kesdtksfyegaaEYVSHELVNAALLAGSRDNITVMVIFLN
             | . ..||..|| .|.||||||.|..|.
.............eeaaerlvelalarggrDNiTvvvvrld

PP2C Protein phosphatase 2C 358-472 6e-26 84.5 Pfam-A 114-227 (255) alignment
Range on Protein: 358-472
Range on HMM: 114-227/255.0
LHVANTGNVQAVLCRNGKGF-CLTKEHTTRNTNERRRILQNGAVISSnepYGLVEGQVKTTRGLGFHGNLK-LKKSIIPAPQTISVPIDDLCQFLIVATN
|.|||.|  .|||||... .  ||. |.. ...||.|| ..|  .|     | | |... .| || .   .  .. ....|.. ||....  .|||.|. 
lyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpkeeqlvsaePdvtsvklteedefliLasd

GLWEVLDKEEVTALAMT
|||.||...|.  |.  
Glwdvlsdqeavdlvrs

PP2C Protein phosphatase 2C 358-472 6e-26 84.5 In-house 114-227 (255) alignment
Range on Protein: 358-472
Range on HMM: 114-227/255.0
LHVANTGNVQAVLCRNGKGF-CLTKEHTTRNTNERRRILQNGAVISSnepYGLVEGQVKTTRGLGFHGNLK-LKKSIIPAPQTISVPIDDLCQFLIVATN
|.|||.|  .|||||... .  ||. |.. ...||.|| ..|  .|     | | |... .| || .   .  .. ....|.. ||....  .|||.|. 
lyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpkeeqlvsaePdvtsvklteedefliLasd

GLWEVLDKEEVTALAMT
|||.||...|.  |.  
Glwdvlsdqeavdlvrs

PPM_PTC7 358-472 2.1e-24 79.3 In-house 115-232 (259) alignment
Range on Protein: 358-472
Range on HMM: 115-232/259.0
LHVANTGNVQAVLCRNGKGF-CLTKEHTTRNTNERRRILQNGAVISSNePYGLVEGQVKTTRGLGFHGNLK---LKKSIIPAPQTISVPIDDLCQFLIVA
|.|||.|. .|||||.|. .  ||. |.. |..||.|| ..|  .|.    | | |..  .| .| . . .    .. ....|.. |..||.  .|||.|
lyvAnvGDSravLcrsgnavkqltedHkpsnedEreRiegaggsvsnv.gngrvngvlavsRafGdfelkpketeeqlvsaePdisstkideedefliLa

TNGLWEVLDKEEVTALAMT
. |||.|....|.  |. .
sdGlwdvvsdqeavdlvrs

subfamily_PPM1E_pd Subfamily PPM1E 356-475 3.3e-18 58.8 In-house 114-229 (265) alignment
Range on Protein: 356-475
Range on HMM: 114-229/265.0
GILHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEPYgLVEGQVKTTRGLGfhgNLKLKKSIIPAPQTISVPIDDLCQFLIVATN
  |.||  |. ||.|.|.|.   |.| |   . .|..|| ..| ..   . .  | |..  .| .|   . |||. ..  ... .|..|. ...||.|..
dqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigaw.RvnGvLsvsRaiG...DvklkpyvsgeadvaeveldgseeylilacD

GLWEVLDKEEVTALAMTTFH
|||.|...|||. |    ..
GlwDvvneeevvklveefla

subfamily_PPM1K_pd Subfamily PPM1K 358-469 2.3e-17 56.0 In-house 113-224 (263) alignment
Range on Protein: 358-469
Range on HMM: 113-224/263.0
LHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSN-EPYGLVEGQVKTTRGLGfhgNLKLKKS-IIPAPQTISVPID-DLCQFLIVAT
| .|..|. .|.||||||  .||..|.    .|..||.. |  ...|     ||.|..  || ||   .|.||.. .|  |.| |. .| .   ||.. |
lvlaslGdsrailcrnGkakkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtrslG...dldlkryGviatPetkslkvdhaadsflvlit

NGLWEVLDKEEVTAL
.|.  |....|.. |
dgisfvvnsqelcdl

subfamily_PHLPP_pd Subfamily PHLPP 356-467 1.9e-16 52.7 In-house 105-209 (246) alignment
Range on Protein: 356-467
Range on HMM: 105-209/246.0
GILHVANTGNVQAVLCRNGKGFCLTKEHTTRNTnERRRILQNGAVISSNepyGLVEGQVKTTRGLGFhgnLKLKKSIIPAPQTISVPIDDLCQFLIVATN
  |.||..|..||||.|||| . |.|...  .  | .|| .. |.|. .   . ..| ...|| ||.   . |  ...| |.  .|.. .   .|||  .
fsLevAsvGtlqavliRngkklrlsksyviekd.elkrikeakaiited...nkingviestrllGy...tflfPvvlPkphvrevlLteqdellivGnk

GLWEVLDKEEVT
 |||||. .|..
alWevlsideav

subfamily_ILKAP_pd Subfamily ILKAP 353-476 1.2e-15 50.5 In-house 122-245 (293) alignment
Range on Protein: 353-476
Range on HMM: 122-245/293.0
IISGILHVANTGNVQAVLCRNG-K-----GFCLTKEHTTRNTNERRRILQNGAVISSNEpyglVEGQVKTTRGLGfHGNLKlKKSIIPAPQTISVPIDDL
..  .|.||| |. .|||.|.  .       .|||.||. . .||.|| . |.|.  .     | | .. .| .|  |. | .  .|  |..  . ... 
vldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaGgvvrdgr....vlGvlevsrsiG.dgrfk.rlGvistPdvkkceLten

CQFLIVATNGLWEVLDKEEVTALAMTTFHM
 .|...| .|||.|....||   .. ... 
dlfvvlaCdGLwkvfsadevvkfilkvled

subfamily_PPM1L_pd Subfamily PPM1L 358-470 1.8e-15 49.9 In-house 120-232 (269) alignment
Range on Protein: 358-470
Range on HMM: 120-232/269.0
LHVANTGNVQAVLC-RNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEPYgLVEGQVKTTRGLGFHgNLKLKKSIIPAPQTISVPIDDL-CQFLIVATN
| ||| |. . ||. ..||   |. .|  .. .||.|| . |  |. .  .  |.| . |.| || .  || |. .|. |. ..  .||.  .|||.|..
livanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvw.rvaGvlatsralGdy.plkdknlviadpdiltfdlddhkpeflilasd

GLWEVLDKEEVTALA
|||. .  ||    .
Glwdtfsneeavrfi

subfamily_PPM1G_pd Subfamily PPM1G 357-471 3.3e-13 42.5 In-house 309-426 (473) alignment
Range on Protein: 357-471
Range on HMM: 309-426/473.0
ILHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNepyGLVEGQVKTTRGLGFHgNLKLKKSIIPAPQTIS-------VPIDDLCQF
 | ||| |.  .||.||||   |  .|   . .|..|| . |  . ..   | |.| .   | || | . | .... .  | ||         . .  .|
klivAnaGDsRcvlsrnGkAldlslDHkPeDevEleRiekAGGkvded...gRvnGGLnlsRAlGDh.aYkkneeLplkeqmisAlPDikvltlteedeF

LIVATNGLWEVLDKEEVTALAM
|..|..|.| |.. .||     
lvlAcDGiWnvmesqevvdfvr

subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 353-470 8.2e-13 41.2 In-house 104-220 (255) alignment
Range on Protein: 353-470
Range on HMM: 104-220/255.0
IISGILHVANTGNVQAVLC-RNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEPYGLVEGQVKTTRGLGfhgNLKLKKSIIPAPQTI-SVPIDDLCQFL
||     .|| |. ..||| ..|    |. .|   . .|..|| . |  . |.     |.|..  .| ||   .  |.  ..| |.   |. |    .||
iiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralG...dsflePfvvpdPdlsqsleiskkdkfl

IVATNGLWEVLDKEEVTALA
|.| .|.|...  ||   ..
ilacdGiwdlisdeeaveiv

subfamily_PPM1G2_pd Subfamily PPM1G2 356-472 7.6e-12 37.8 In-house 127-245 (287) alignment
Range on Protein: 356-472
Range on HMM: 127-245/287.0
GILHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEpyglVEGQVKTTRGLG---FHGNLKL--K-KSIIPAPQTISVPIDDLCQF
  | |||.|. .|||. .|.   |. .|  ....|..|| ..| ... |     | |..   | ||   |  | |.  . . .   |  .   .|.   |
eklyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfvelnr....vngnLalsralgDfefkknvkkkpeeqivtavPDvlvkkldeddef

LIVATNGLWEVLDKEEVTALAMT
|..| .|.|.|| ..||  |  .
lvLaCDGiWDvltnkevvdlvre

subfamily_KAPP-like_pd Subfamily KAPP-like 358-465 1.5e-11 36.8 In-house 118-223 (266) alignment
Range on Protein: 358-465
Range on HMM: 118-223/266.0
LHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEpyGLVEGqVKTTRGLGFHGNLKLKKSIIPAPQtISV--PIDDLCQFLIVATN
| ||| |.  | |.|  . . |.|.| ... .|..|| ..|  .| |.    ..| .  .| || |   .|   .|  |  .|    .    .|||||..
lqvanvGdssaflsrGneslelskdhkakdpeekqrikddGitlsdnq..trinG.lavsralGdhfikelniGlisepy.vsnrilltpfdkflivasd

GLWEVLDKEE
|||.|.. ..
GlwdvisGkd

subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 358-465 2e-11 36.3 In-house 128-233 (276) alignment
Range on Protein: 358-465
Range on HMM: 128-233/276.0
LHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEpyGLVEGqVKTTRGLGFHGNLKLKKSIIPAPQtISV--PIDDLCQFLIVATN
| ||| |.  | |.|  . . |.|.| . . .|..|| ..|  .| |.    ..| .  .| || |   .|   .|  |  .|    .    .|||||..
lqvanvGdssaflsrGneslelskdhkatdpeekqrikddGitlsdnq..trinG.lavsralGdhfikelniGlisepy.vsnrilltpfdkflivasd

GLWEVLDKEE
|||.|.. ..
GlwdvisGkd

subfamily_PDP_pd Subfamily PDP 199-396 3.5e-11 35.8 In-house 23-209 (398) alignment
Range on Protein: 199-396
Range on HMM: 23-209/398.0
PNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQM--TTDEQQIINSFYTVFREEYAA----IEDLFSAINKT---EAVRCEYEDTHKAFAKA
 | ..||.|||| || .||  | .|.  .  .| | .   ..  .. ... .... .. ....       ..|. . ...   |..  | |....|  ||
sngvlfgvfDGHggaacaeavskrLlkyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslselskylqelleaevekvkealkka

FWRMDRLLGLGRKEVSrvqwsgcsavtcilegkpkspyaHKNWKRKNTHDGLAESspSQEMPKIISGILHVANTGNVQAVLCR-NGKG----FCLTKEHT
| ..|. .     . .                       ...  |.... .|. .     .  | .  |||||||  .|||.. ...|      |.|..|
FlklDkdistealkkl.......................kekslreallvalsGa..callaliegtelhvAntGDcravlgvqeeegsweavkLskdqt

TRNTNERRRILQ
..|..| .|| .
adneeEveRikk

PPM_PTC7_SpoIIE 355-471 1.1e-08 28.1 In-house 104-206 (230) alignment
Range on Protein: 355-471
Range on HMM: 104-206/230.0
SGILHVANTGNVQAVLCRNGKGfcltkehttrntnERRRILQNGAV-IS--SNEPYGLvegqVKTTRGLGFHGNLKLKKSIIPAPQTISVPIDDLCQFLI
.|.|.||| |.  ..|.|...|             ||.||   |.. ..  .. ..|     .  ..  |    |   . . . |.|.    ..  .|||
tgklyvanaGdsppllvrddgg.............ererivagglpslGilpgrvfgv....lavslapGdllllytDGvveaepdtsdgelfgkdefli

VATNGLWEVLDKEEVTALAM
.|. |||.||. .|.  |..
lasdglwdvlspqelvdlvr

subfamily_PPM1L_pd Subfamily PPM1L 183-263 2.3e-08 26.6 In-house 17-92 (269) alignment
Range on Protein: 183-263
Range on HMM: 17-92/269.0
ADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFdpsyqMTTDEQQIINSFYTVFREEYAAIE
  |.|.|..  .  || .  ||..|||| |  ||| .   |.  ....| ..      .  |...  .| ... .|  ...
prmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknkliel.....dadkentepinfsklltdeilsvd

subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 182-234 1.2e-07 24.3 In-house 17-69 (255) alignment
Range on Protein: 182-234
Range on HMM: 17-69/255.0
KADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKF
.. |.|....  .| .|..  .. ||||| | .||. .| ||. .| . |  .
rptmedelviyGsfrdksdedyyalfdGhgGraaakfaseelykilaelldln

subfamily_PPM1H_pd Subfamily PPM1H 192-319 1.3e-07 23.7 In-house 53-172 (404) alignment
Range on Protein: 192-319
Range on HMM: 53-172/404.0
VSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQMTTDEQQiiNSFYTVFREEYAAIEDLFsainKTEAVRCEyEDTHKAFAKAFW
 ... .| .. .||||||| | .|| ..|  |   | ..|..     . . .|..  . . .. .|.  . .. .    . . .. | |    |. .|| 
ekseeeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellleksaeee..enteesskespssvseiy....eekeiske.eLviGalesafl

RMDRLLGLGRKEVsrVQWSGCSAVTCI-L
.|| ..   |..    .  ||.|.  . |
emDeqiarereay..rikGGCtalvalvl

subfamily_PPM1G2_pd Subfamily PPM1G2 180-319 7.9e-07 21.3 In-house 28-124 (287) alignment
Range on Protein: 180-319
Range on HMM: 28-124/287.0
TWKADMNDKFTV---VSNFGNKPNVCFFGLFDGHHGASAAELTSMElpvlllhqlskfdpsyqmttdeqqiinsfytvfreeyaaiedL-----Fsaink
 .. .|.|  ..   . .  ..... .|..|||| ||..|. .. .                                          |           
GyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkk..........................................likkiak.....

teavRCEYE--DTHKAFAKAFWRMDRLLglGRKEVSRVQWSGCSAVTCIL
    . ...    .... .|| ..|. |   ..|  . . .|. ||. ..
....kksfkegaleqilkdafletDeel..lkdeklkdesaGstavvvli

subfamily_PPM1E_pd Subfamily PPM1E 184-237 1.4e-06 20.7 In-house 17-77 (265) alignment
Range on Protein: 184-237
Range on HMM: 17-77/265.0
DMNDKFTVVSNF------GNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKF-DPS
 |.|.. .....       ....  ||. |||| |  ||. ....|. || .| .   || 
kmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa

subfamily_PPM1G_pd Subfamily PPM1G 179-230 1.6e-06 20.4 In-house 27-76 (473) alignment
Range on Protein: 179-230
Range on HMM: 27-76/473.0
STWKADMNDKFTVVSNFGNKpnVCFFGLFDGHHGASAAELTSMELPVLLLHQ
  |.... |  ... .. ..  . .|. .||| |.  |. .. .|| || .|
qGwrvsqEDahncitdlded..tslfavyDGHGGkevakyvakklpdllkaq

subfamily_PPM1D_pd Subfamily PPM1D 182-286 6.1e-06 18.5 In-house 13-90 (309) alignment
Range on Protein: 182-286
Range on HMM: 13-90/309.0
KADMNDKFTVVSNFG---NKPNVCFFGLFDGHHGASAAELTSMELPVlLLHQLSKFdpsyqMTTDEQQIinsfytvfreeyaaiedlfsainkTEAVRCE
.  |.| ...|..     .. .| |...|||| |  ||. .. .|    ... .||     ........                        .||.|  
rkymeDvvaivleeeesaeelevafvavfDGHGGkeAakfarehlws.vikkqkkf.....lssepedv........................leAirea

YEDTHKAF
. .||.| 
flatheam

subfamily_PDP_pd Subfamily PDP 435-472 7.3e-06 18.3 In-house 273-310 (398) alignment
Range on Protein: 435-472
Range on HMM: 273-310/398.0
APQTISVPIDDLCQFLIVATNGLWEVLDKEEVTALAMT
 |. .| ..    .||..|| |||..|..|||  | . 
ePevtshklrendkFLvlatDGLwdllsneevvslVge

subfamily_ILKAP_pd Subfamily ILKAP 183-257 8.7e-06 18.1 In-house 17-95 (293) alignment
Range on Protein: 183-257
Range on HMM: 17-95/293.0
ADMNDKFTVVSNFGNK--------PNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDpsyqMTTDEQQIINSFYTVFRE
..|.|. ...... ..         .|.....|||| |  |.| .. .|   .|..|.| |    ... |..| ...   |..
eemqdahviledldeqlrlekslvsrvsyyavfdGhaGsrasefaaeklhkkileklpksd....vsakekeikkclvdsfkk