Gene PP2D1 in Homo sapiens

Synonym: C3orf48, PP2D1

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PP2D1
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP173_AA protein Get Run
HsapP173_AA_164-623 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PP2D1_pd Subfamily PP2D1 169-624 1.1e-216 713.3 In-house 1-492 (492) alignment 
Range on Protein: 169-624
Range on HMM: 1-492/492.0
KGVGICEDRNSTWKADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQMTTDEQQIINSFYTVFREEYAAIEDLFSA
|.||||||.||.||..|.||.|....|||..|.||||..||..||.|||....||...||..|.|.|.....||....|.|...|....|.|...|...|
kavGiCedknsrWKskmeDkrtlqdyfgndvnscFfgiyDGynGataAeiaakelhevlleelekvdervslttavnlidnndltdyelerasrsdsira

INKTEAVRCEYEDTHKAFAKAFWRMDRLLGLGRKEVSRVQWSGCSAVTCILEGKPKSPYAHKNWKRKNTHDGLAESSPSQEMPKIISGILHVANTGNVQA
|.|.|.|..|.|...|||.|...|.||||..|..|.|||.||||||.|..|||......|......|....||...|...|......|.|..||.|||||
ilkeesvkpefekvkkAfrksylrldrlLsygieeesrvrWsGCsAltllleGnkreteatekeekkdseeGlekesngsevhleelgvlyianaGnvqA

VLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEPYGLVEGQVKTTRGLGFHGNLKLKKSIIPAPQTISVPIDDLCQFLIVATNGLWEVLDKEEVTA
||||.||...||.|||.||..||.|. ..|.|....|..|||.|...||||||..|..|||||.||.|.|.||..|. .|||..|.|||||||..|||..
vLcreGkaiiLtreHtprnkkERtRvekagsvvvkseknglvnGildttRGLGnyGdpkLkksvipePkttsvkldeaaqflvlAsnGlWevlseeevls

LAMTTFHMYK----------------------ETYCPIIPNKSPSKGPLLFSTSEPNLTKSQ---SNIHVLFQYKSVSEVRVSTTNSKENLSDSNYSKYC
|...|...||                      |.............|.  |.|||..|....   ||...||.|...|||........|.||..|..|..
LvkqtlaiyksrvraenvpdsdvttvgedylgEleakklsaryentgfdkfvtseidldaaegdesnlqklfsynelsevkedaddereglseanskkei

IYNPENVETFPAETTHRKPCSEKVTDRPTSVNDVATN---EKESDTKSF--------YEGAAEYVSHELVNAALLAGSRDNITVMVIFLNGS
.||.|.......|....|...||.|.|...|..||.|   |||..|||.        ||.|||..|..||..|||||||||||||||.|.|.
tyneedtdksaeeskeaksseekstnrsirveevaenvkaekeeetksdgivdkkekyelaAealserlvqsALlAGsrDnitvmvilLkGc
0034914 PP2C-like 165-623 2.5e-52 170.5 In-house 17-292 (295) alignment 
Range on Protein: 165-623
Range on HMM: 17-292/295.0
HLLIKGVGICEDRNStwKADMNDKFTVVSNFGN-KPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQMTtdeqqiinsfytvfreeyaaie
.||.  ||.. |..   .  . | ..|| |. .  .....||.|||| | .|||. |  |. |||..| |.. .....                      
lllllrvgvasdqGr..rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltls......................

dlfsainkteavrceYEDTHKAFAKAFWRMDRLLGLGRKEVSRVQWSGCSAVTCILEGKpkspyahknwkrknthdglaesspsqempkiisgILHVANT
               .|| ..|. |||...|. |     . .....||..||.... |.                                   |.|||.
...............ledieealrkaflaadeellelallrpelagsGtTavvalirgn..................................klyvanv

GNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSnepyGLVEGQVKTTRGLGFHGNLK------LKKSIIPAPQTISVPID-DLCQFLIVATNG
|. .|||.|||.  .||..|.  |  ||.|||..| ..|     | | |.   || ||..  ..      |.  ... |........ . ..||..|. |
GDSravllrngelvqltvdhkpvnelererilsaggavsh....grvngvlavtRalGdfdlklllslllleplvsaePdvtvleltledddfllLasDG

LWEVLDKEEVTALAMTTFHMYKEtycpiipnkspskgpllfstsepnltksqsnihvlfqyksvsevrvsttnskenlsdsnyskyciynpenvetfpae
||.||. ||. ........ ...                                                                             
lwdvlsneeivdivrsllakgld.............................................................................

tthrkpcsekvtdrptsvndvatnekesdtksfyegaAEYVSHELVNAALLAGSRDNITVMVIFLNG
                                     .|....|||..|| .||||||||.|..|||
.....................................leeaaeeLvdlAlargsrDNiTvvvvrlng
subfamily_PPM1A_pd Subfamily PPM1A 176-622 6.3e-39 127.0 In-house 17-281 (282) alignment 
Range on Protein: 176-622
Range on HMM: 17-281/282.0
DRNSTWKADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHqlskfdpsyqmttdeqqiinsfytvfreeyaaiE----Dlfsaink
. .. |...| |..||| ..|. ..  || .|||| |...|. .. .|.  .|.                                 |    .       
ssmqgwrvemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenile.................................eeelke.......

TEAVRCEYEDTHKAFAKAFWRMDRLLGLGRKEVSRVQWSGCSAVTCILEgkpkspyahknwkrknthdglaesspsqempkiiSGILHVANTGNVQAVLC
... . | .....|. ..| ..|  .    ....  . ||. |||....                                     | .|| |   ||||
aaleasekdevkealrqgfLaldeairelstdlktadksGsTavtvlvs..................................ekhliianlGDsRavlc

RNGKGFCLTKEHTTRNTNERRRILQNGAVISsnepYGLVEGQVKTTRGLGFHGNLK------LKKSIIPAPQTISVPIDDLCQFLIVATNGLWEVLDKEE
||||   ||..|   ...|..|| | |  .      . |.|.   .| || .   .       .. ... |.. |. ...  .||..|  |.|.||. ||
rngkaaflteDHkpsrpkEkkRieqAGGsvv....vsRvnGaLAvsRalGDyeykeeeekkaeeqlvsaepevtsierseeddflvlacDGiwDvlsdee

VTALAMTTFHMYKETYCPiipnkspskgpllfstsepnltksqsnihvlfqyksvsevrvsttnskenlsdsnyskyciynpenvetfpaetthrkpcse
|..|. ..... .|                                                                                      
vvelvrkrlevadeleev..................................................................................

kvtdrptsvndvatnekesdtksfyegaaeyvSHELVNAALLAGSRDNITVMVIFLN
                                ...||. || .|||||..|.|....
................................akalvdkalekgsrDNlsvlvvlfa
PP2Cc_SM00332 177-473 7.5e-39 126.7 In-house 16-239 (274) alignment 
Range on Protein: 177-473
Range on HMM: 16-239/274.0
RNSTWKADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYqmttdeqqiinsfytvfreeyaaiedlfsainkteavr
 . .|.  |.| . || .. .. .. |||.|||| |...|...| .||  |  .|.| .  .                                      
smqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel......................................

ceYEDTHKAFAKAFWRMDRLLGLG-RKEVSRVQWSGCSAVTCILEGKPkspyahknwkrknthdglaesspsqempkiisgiLHVANTGNVQAVLCRNGK
  ..|. .| .||| ..|  .    ...  . . ||..||...| ..                                   |.|||.|  .||||||||
..eddveealkkaflstdeeileeeqskelenalsGstavvallkked..................................lyvanvGDSravlcrngk

GFCLTKEHTTRNTNERRRILQNGAVISSNepygLVEGQVKTTRGLGFHGNL----KLKKSIIPAPQTISVPIDDLCQFLIVATNGLWEVLDKEEVTALAM
   |...|.. . .||.|| ..|.|.. .     | |. . .| .| |       . .. |.. |..  | ...  .|||.|. |||.||...||  . .
avqlsvdhkpedederkRikkaggvvekg....rvngglavsrafGdhflkknkklkepyitaepdvkvvtltsedeflilaSDGlwdvlsnqevvdivr

TT
 .
kl
0049733 PP2C-like 182-622 2.7e-30 98.5 In-house 15-234 (235) alignment 
Range on Protein: 182-622
Range on HMM: 15-234/235.0
KADMNDKFTVvsnfgnkpNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYqmttdeqqiinsfytvfreeyaaiedlfsainkteavrceyed
.  . | . |        .. .|...||| |. |.|. |  |. .||..| ....                                             
rkvneDavlv........glllfavaDGhgghaagevasellvetllelllelllld...........................................

THKAFAKAFWRMDRLLGLGRKEVSRVQWSGCSAVTCILEGKPkspyahknwkrknthdglaesspsqempkiisgiLHVANTGNVQAVLCRNGKGFCLTK
. .|. |||..... |    ..   ....|..||...| |.                                   |.||| |.  |.|.|.||  .||.
leealrkaflaaneallelalaspelagmgtTavvalldggk..................................lyvanvGDsrayllrdgklvqlte

EHTTRNTNERRRILQNGAVIssnepygLVEGQVKTTRGLGfHGNLKlkksiipaPQTISVPIDDLCqFLIVATNGLWEVLDKEEVTALAMTtFHMykety
.|.  |  ||.||.. | ..        | |.   || || .  ||        |.. ...... . ||..|. |||.||. ||. .| ..  ..     
dhspvnelerqriitaggav.......rvpgrlaltralG.dlllk........pdvtvlelepgd.flllasDGlwdvlsdeeivdllrs.ldl.....

cpiipnkspskgpllfstsepnltksqsnihvlfqyksvsevrvsttnskenlsdsnyskyciynpenvetfpaetthrkpcsekvtdrptsvndvatne
                                                                                                    
....................................................................................................

kesdtksfyegaaEYVSHELVNAALLAGSRDNITVMVIFLN
             | . ..||..|| .|.||||||.|..|.
.............eeaaerlvelalarggrDNiTvvvvrld
PP2C Protein phosphatase 2C 358-472 6e-26 84.5 Pfam-A 114-227 (255) alignment 
Range on Protein: 358-472
Range on HMM: 114-227/255.0
LHVANTGNVQAVLCRNGKGF-CLTKEHTTRNTNERRRILQNGAVISSnepYGLVEGQVKTTRGLGFHGNLK-LKKSIIPAPQTISVPIDDLCQFLIVATN
|.|||.|  .|||||... .  ||. |.. ...||.|| ..|  .|     | | |... .| || .   .  .. ....|.. ||....  .|||.|. 
lyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpkeeqlvsaePdvtsvklteedefliLasd

GLWEVLDKEEVTALAMT
|||.||...|.  |.  
Glwdvlsdqeavdlvrs
PP2C Protein phosphatase 2C 358-472 6e-26 84.5 In-house 114-227 (255) alignment 
Range on Protein: 358-472
Range on HMM: 114-227/255.0
LHVANTGNVQAVLCRNGKGF-CLTKEHTTRNTNERRRILQNGAVISSnepYGLVEGQVKTTRGLGFHGNLK-LKKSIIPAPQTISVPIDDLCQFLIVATN
|.|||.|  .|||||... .  ||. |.. ...||.|| ..|  .|     | | |... .| || .   .  .. ....|.. ||....  .|||.|. 
lyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpkeeqlvsaePdvtsvklteedefliLasd

GLWEVLDKEEVTALAMT
|||.||...|.  |.  
Glwdvlsdqeavdlvrs
PPM_PTC7 358-472 2.1e-24 79.3 In-house 115-232 (259) alignment 
Range on Protein: 358-472
Range on HMM: 115-232/259.0
LHVANTGNVQAVLCRNGKGF-CLTKEHTTRNTNERRRILQNGAVISSNePYGLVEGQVKTTRGLGFHGNLK---LKKSIIPAPQTISVPIDDLCQFLIVA
|.|||.|. .|||||.|. .  ||. |.. |..||.|| ..|  .|.    | | |..  .| .| . . .    .. ....|.. |..||.  .|||.|
lyvAnvGDSravLcrsgnavkqltedHkpsnedEreRiegaggsvsnv.gngrvngvlavsRafGdfelkpketeeqlvsaePdisstkideedefliLa

TNGLWEVLDKEEVTALAMT
. |||.|....|.  |. .
sdGlwdvvsdqeavdlvrs
subfamily_PPM1E_pd Subfamily PPM1E 356-475 3.3e-18 58.8 In-house 114-229 (265) alignment 
Range on Protein: 356-475
Range on HMM: 114-229/265.0
GILHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEPYgLVEGQVKTTRGLGfhgNLKLKKSIIPAPQTISVPIDDLCQFLIVATN
  |.||  |. ||.|.|.|.   |.| |   . .|..|| ..| ..   . .  | |..  .| .|   . |||. ..  ... .|..|. ...||.|..
dqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigaw.RvnGvLsvsRaiG...DvklkpyvsgeadvaeveldgseeylilacD

GLWEVLDKEEVTALAMTTFH
|||.|...|||. |    ..
GlwDvvneeevvklveefla
subfamily_PPM1K_pd Subfamily PPM1K 358-469 2.3e-17 56.0 In-house 113-224 (263) alignment 
Range on Protein: 358-469
Range on HMM: 113-224/263.0
LHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSN-EPYGLVEGQVKTTRGLGfhgNLKLKKS-IIPAPQTISVPID-DLCQFLIVAT
| .|..|. .|.||||||  .||..|.    .|..||.. |  ...|     ||.|..  || ||   .|.||.. .|  |.| |. .| .   ||.. |
lvlaslGdsrailcrnGkakkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtrslG...dldlkryGviatPetkslkvdhaadsflvlit

NGLWEVLDKEEVTAL
.|.  |....|.. |
dgisfvvnsqelcdl
subfamily_PHLPP_pd Subfamily PHLPP 356-467 1.9e-16 52.7 In-house 105-209 (246) alignment 
Range on Protein: 356-467
Range on HMM: 105-209/246.0
GILHVANTGNVQAVLCRNGKGFCLTKEHTTRNTnERRRILQNGAVISSNepyGLVEGQVKTTRGLGFhgnLKLKKSIIPAPQTISVPIDDLCQFLIVATN
  |.||..|..||||.|||| . |.|...  .  | .|| .. |.|. .   . ..| ...|| ||.   . |  ...| |.  .|.. .   .|||  .
fsLevAsvGtlqavliRngkklrlsksyviekd.elkrikeakaiited...nkingviestrllGy...tflfPvvlPkphvrevlLteqdellivGnk

GLWEVLDKEEVT
 |||||. .|..
alWevlsideav
subfamily_ILKAP_pd Subfamily ILKAP 353-476 1.2e-15 50.5 In-house 122-245 (293) alignment 
Range on Protein: 353-476
Range on HMM: 122-245/293.0
IISGILHVANTGNVQAVLCRNG-K-----GFCLTKEHTTRNTNERRRILQNGAVISSNEpyglVEGQVKTTRGLGfHGNLKlKKSIIPAPQTISVPIDDL
..  .|.||| |. .|||.|.  .       .|||.||. . .||.|| . |.|.  .     | | .. .| .|  |. | .  .|  |..  . ... 
vldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaGgvvrdgr....vlGvlevsrsiG.dgrfk.rlGvistPdvkkceLten

CQFLIVATNGLWEVLDKEEVTALAMTTFHM
 .|...| .|||.|....||   .. ... 
dlfvvlaCdGLwkvfsadevvkfilkvled
subfamily_PPM1L_pd Subfamily PPM1L 358-470 1.8e-15 49.9 In-house 120-232 (269) alignment 
Range on Protein: 358-470
Range on HMM: 120-232/269.0
LHVANTGNVQAVLC-RNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEPYgLVEGQVKTTRGLGFHgNLKLKKSIIPAPQTISVPIDDL-CQFLIVATN
| ||| |. . ||. ..||   |. .|  .. .||.|| . |  |. .  .  |.| . |.| || .  || |. .|. |. ..  .||.  .|||.|..
livanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvw.rvaGvlatsralGdy.plkdknlviadpdiltfdlddhkpeflilasd

GLWEVLDKEEVTALA
|||. .  ||    .
Glwdtfsneeavrfi
subfamily_PPM1G_pd Subfamily PPM1G 357-471 3.3e-13 42.5 In-house 309-426 (473) alignment 
Range on Protein: 357-471
Range on HMM: 309-426/473.0
ILHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNepyGLVEGQVKTTRGLGFHgNLKLKKSIIPAPQTIS-------VPIDDLCQF
 | ||| |.  .||.||||   |  .|   . .|..|| . |  . ..   | |.| .   | || | . | .... .  | ||         . .  .|
klivAnaGDsRcvlsrnGkAldlslDHkPeDevEleRiekAGGkvded...gRvnGGLnlsRAlGDh.aYkkneeLplkeqmisAlPDikvltlteedeF

LIVATNGLWEVLDKEEVTALAM
|..|..|.| |.. .||     
lvlAcDGiWnvmesqevvdfvr
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 353-470 8.2e-13 41.2 In-house 104-220 (255) alignment 
Range on Protein: 353-470
Range on HMM: 104-220/255.0
IISGILHVANTGNVQAVLC-RNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEPYGLVEGQVKTTRGLGfhgNLKLKKSIIPAPQTI-SVPIDDLCQFL
||     .|| |. ..||| ..|    |. .|   . .|..|| . |  . |.     |.|..  .| ||   .  |.  ..| |.   |. |    .||
iiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralG...dsflePfvvpdPdlsqsleiskkdkfl

IVATNGLWEVLDKEEVTALA
|.| .|.|...  ||   ..
ilacdGiwdlisdeeaveiv
subfamily_PPM1G2_pd Subfamily PPM1G2 356-472 7.6e-12 37.8 In-house 127-245 (287) alignment 
Range on Protein: 356-472
Range on HMM: 127-245/287.0
GILHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEpyglVEGQVKTTRGLG---FHGNLKL--K-KSIIPAPQTISVPIDDLCQF
  | |||.|. .|||. .|.   |. .|  ....|..|| ..| ... |     | |..   | ||   |  | |.  . . .   |  .   .|.   |
eklyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfvelnr....vngnLalsralgDfefkknvkkkpeeqivtavPDvlvkkldeddef

LIVATNGLWEVLDKEEVTALAMT
|..| .|.|.|| ..||  |  .
lvLaCDGiWDvltnkevvdlvre
subfamily_KAPP-like_pd Subfamily KAPP-like 358-465 1.5e-11 36.8 In-house 118-223 (266) alignment 
Range on Protein: 358-465
Range on HMM: 118-223/266.0
LHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEpyGLVEGqVKTTRGLGFHGNLKLKKSIIPAPQtISV--PIDDLCQFLIVATN
| ||| |.  | |.|  . . |.|.| ... .|..|| ..|  .| |.    ..| .  .| || |   .|   .|  |  .|    .    .|||||..
lqvanvGdssaflsrGneslelskdhkakdpeekqrikddGitlsdnq..trinG.lavsralGdhfikelniGlisepy.vsnrilltpfdkflivasd

GLWEVLDKEE
|||.|.. ..
GlwdvisGkd
subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 358-465 2e-11 36.3 In-house 128-233 (276) alignment 
Range on Protein: 358-465
Range on HMM: 128-233/276.0
LHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEpyGLVEGqVKTTRGLGFHGNLKLKKSIIPAPQtISV--PIDDLCQFLIVATN
| ||| |.  | |.|  . . |.|.| . . .|..|| ..|  .| |.    ..| .  .| || |   .|   .|  |  .|    .    .|||||..
lqvanvGdssaflsrGneslelskdhkatdpeekqrikddGitlsdnq..trinG.lavsralGdhfikelniGlisepy.vsnrilltpfdkflivasd

GLWEVLDKEE
|||.|.. ..
GlwdvisGkd
subfamily_PDP_pd Subfamily PDP 199-396 3.5e-11 35.8 In-house 23-209 (398) alignment 
Range on Protein: 199-396
Range on HMM: 23-209/398.0
PNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQM--TTDEQQIINSFYTVFREEYAA----IEDLFSAINKT---EAVRCEYEDTHKAFAKA
 | ..||.|||| || .||  | .|.  .  .| | .   ..  .. ... .... .. ....       ..|. . ...   |..  | |....|  ||
sngvlfgvfDGHggaacaeavskrLlkyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslselskylqelleaevekvkealkka

FWRMDRLLGLGRKEVSrvqwsgcsavtcilegkpkspyaHKNWKRKNTHDGLAESspSQEMPKIISGILHVANTGNVQAVLCR-NGKG----FCLTKEHT
| ..|. .     . .                       ...  |.... .|. .     .  | .  |||||||  .|||.. ...|      |.|..|
FlklDkdistealkkl.......................kekslreallvalsGa..callaliegtelhvAntGDcravlgvqeeegsweavkLskdqt

TRNTNERRRILQ
..|..| .|| .
adneeEveRikk
PPM_PTC7_SpoIIE 355-471 1.1e-08 28.1 In-house 104-206 (230) alignment 
Range on Protein: 355-471
Range on HMM: 104-206/230.0
SGILHVANTGNVQAVLCRNGKGfcltkehttrntnERRRILQNGAV-IS--SNEPYGLvegqVKTTRGLGFHGNLKLKKSIIPAPQTISVPIDDLCQFLI
.|.|.||| |.  ..|.|...|             ||.||   |.. ..  .. ..|     .  ..  |    |   . . . |.|.    ..  .|||
tgklyvanaGdsppllvrddgg.............ererivagglpslGilpgrvfgv....lavslapGdllllytDGvveaepdtsdgelfgkdefli

VATNGLWEVLDKEEVTALAM
.|. |||.||. .|.  |..
lasdglwdvlspqelvdlvr
subfamily_PPM1L_pd Subfamily PPM1L 183-263 2.3e-08 26.6 In-house 17-92 (269) alignment 
Range on Protein: 183-263
Range on HMM: 17-92/269.0
ADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFdpsyqMTTDEQQIINSFYTVFREEYAAIE
  |.|.|..  .  || .  ||..|||| |  ||| .   |.  ....| ..      .  |...  .| ... .|  ...
prmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknkliel.....dadkentepinfsklltdeilsvd
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 182-234 1.2e-07 24.3 In-house 17-69 (255) alignment 
Range on Protein: 182-234
Range on HMM: 17-69/255.0
KADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKF
.. |.|....  .| .|..  .. ||||| | .||. .| ||. .| . |  .
rptmedelviyGsfrdksdedyyalfdGhgGraaakfaseelykilaelldln
subfamily_PPM1H_pd Subfamily PPM1H 192-319 1.3e-07 23.7 In-house 53-172 (404) alignment 
Range on Protein: 192-319
Range on HMM: 53-172/404.0
VSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQMTTDEQQiiNSFYTVFREEYAAIEDLFsainKTEAVRCEyEDTHKAFAKAFW
 ... .| .. .||||||| | .|| ..|  |   | ..|..     . . .|..  . . .. .|.  . .. .    . . .. | |    |. .|| 
ekseeeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellleksaeee..enteesskespssvseiy....eekeiske.eLviGalesafl

RMDRLLGLGRKEVsrVQWSGCSAVTCI-L
.|| ..   |..    .  ||.|.  . |
emDeqiarereay..rikGGCtalvalvl
subfamily_PPM1G2_pd Subfamily PPM1G2 180-319 7.9e-07 21.3 In-house 28-124 (287) alignment 
Range on Protein: 180-319
Range on HMM: 28-124/287.0
TWKADMNDKFTV---VSNFGNKPNVCFFGLFDGHHGASAAELTSMElpvlllhqlskfdpsyqmttdeqqiinsfytvfreeyaaiedL-----Fsaink
 .. .|.|  ..   . .  ..... .|..|||| ||..|. .. .                                          |           
GyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkk..........................................likkiak.....

teavRCEYE--DTHKAFAKAFWRMDRLLglGRKEVSRVQWSGCSAVTCIL
    . ...    .... .|| ..|. |   ..|  . . .|. ||. ..
....kksfkegaleqilkdafletDeel..lkdeklkdesaGstavvvli
subfamily_PPM1E_pd Subfamily PPM1E 184-237 1.4e-06 20.7 In-house 17-77 (265) alignment 
Range on Protein: 184-237
Range on HMM: 17-77/265.0
DMNDKFTVVSNF------GNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKF-DPS
 |.|.. .....       ....  ||. |||| |  ||. ....|. || .| .   || 
kmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa
subfamily_PPM1G_pd Subfamily PPM1G 179-230 1.6e-06 20.4 In-house 27-76 (473) alignment 
Range on Protein: 179-230
Range on HMM: 27-76/473.0
STWKADMNDKFTVVSNFGNKpnVCFFGLFDGHHGASAAELTSMELPVLLLHQ
  |.... |  ... .. ..  . .|. .||| |.  |. .. .|| || .|
qGwrvsqEDahncitdlded..tslfavyDGHGGkevakyvakklpdllkaq
subfamily_PPM1D_pd Subfamily PPM1D 182-286 6.1e-06 18.5 In-house 13-90 (309) alignment 
Range on Protein: 182-286
Range on HMM: 13-90/309.0
KADMNDKFTVVSNFG---NKPNVCFFGLFDGHHGASAAELTSMELPVlLLHQLSKFdpsyqMTTDEQQIinsfytvfreeyaaiedlfsainkTEAVRCE
.  |.| ...|..     .. .| |...|||| |  ||. .. .|    ... .||     ........                        .||.|  
rkymeDvvaivleeeesaeelevafvavfDGHGGkeAakfarehlws.vikkqkkf.....lssepedv........................leAirea

YEDTHKAF
. .||.| 
flatheam
subfamily_PDP_pd Subfamily PDP 435-472 7.3e-06 18.3 In-house 273-310 (398) alignment 
Range on Protein: 435-472
Range on HMM: 273-310/398.0
APQTISVPIDDLCQFLIVATNGLWEVLDKEEVTALAMT
 |. .| ..    .||..|| |||..|..|||  | . 
ePevtshklrendkFLvlatDGLwdllsneevvslVge
subfamily_ILKAP_pd Subfamily ILKAP 183-257 8.7e-06 18.1 In-house 17-95 (293) alignment 
Range on Protein: 183-257
Range on HMM: 17-95/293.0
ADMNDKFTVVSNFGNK--------PNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDpsyqMTTDEQQIINSFYTVFRE
..|.|. ...... ..         .|.....|||| |  |.| .. .|   .|..|.| |    ... |..| ...   |..
eemqdahviledldeqlrlekslvsrvsyyavfdGhaGsrasefaaeklhkkileklpksd....vsakekeikkclvdsfkk