Gene PPM1J in Homo sapiens

Synonym: PP2CZ, PP2Czeta, PPP2CZ, RP11-426L16.5, PPM1J

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PPM1H
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP182_AA protein Get Run
HsapP182_AA_97-501 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPM1H_pd Subfamily PPM1H 96-498 2.7e-189 622.1 In-house 4-402 (404) alignment 
Range on Protein: 96-498
Range on HMM: 4-402/404.0
DTGRRLPWSTGYAEVINAGKSRHNEDQACCEVVYV---EGRRSVTGVPREPSRGQGLCFYYWGLFDGHAGGGAAEMASRLLHRHIREQLKDLVEILQDPS
 . |||||..|||||||||||..|||||...|...   . ..||| .|.| |. ..|...|.|||||||| ||| .||.|||.|..|.|.|..|.|.. |
relrrlPwaaGYaevinagkselneDqaaakvlllkkekkeksvtskpkekseeeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellleks

PpplclpTTPGTPDSSDPSHLLGPQSCWsSQKEVSHESLVVGAVENAFQLMDEQMARERRGHQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEIIP
.      ... . ..|....   ..... ..||.|.|.||.||.|.||. ||||.||||. ....|||.|||...||||.|||||||||||.||..||||
a......eeeenteesskespssvseiy.eekeiskeeLviGalesaflemDeqiarereayrikGGCtalvalvllgklYvanaGDsRailvrkdeiip

MSREFTPETERQRLQLLGFLKPELLGSEFTHLEFPRRVLPKELGQRMLYRDQNMTGWAYKKIELEDLRFPLVCGEGKKARVMATIGVTRGLGDHSLKVCS
.|..||||||||||| |.||||||||.|||.|||..|.  |.||||.|||||||||||||..| |||.|||..|||||||..||||||||||||.|||..
lsadftPeteRqRlqelaflkPeLlgkeftrlefqkRlkkkdlgqrvlyRdqnmtGWayktveeeDlkfplisgegkkaRllatigvtRGlGDheLkvvd

STLPIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYEPNDHSRYTALAQALVLGARGTPRDRGWRLPNNKLGSGDDIS
..| ||||||..|||||.||||.|...||||.|.|||||||....|||..|..|||..||.|..||||.||.||. |||. .|.|||| ..| .|.||||
tnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvepedkkrytavaqeLvaaarGklkdkgWrlkeekaasvDDis

VFVIPL
||||||
vfviPl
0034914 PP2C-like 100-501 1e-53 175.1 In-house 16-293 (295) alignment 
Range on Protein: 100-501
Range on HMM: 16-293/295.0
RLPWSTGYAEVINAGKSRHNEDQACCEVvyvegrR------SvtgvprepsrgqglcFYYWGLFDGHAGGGAAEMASRLLHRHIREQLKDLVEILQDPsp
 |.... .. . . |....|||. .. .      .      .               ....|.|||| |  |||.||.||.....|.|. |. .|...  
slllllrvgvasdqGrrksneDavlvvl......nllslled...............lllfgvfDGhgGhaaaevasellvelllellekllllltls..

pplclpttpgtpdssdpshllgpqscwssqkevshESLVVGAVENAFQLMDEQMARERRG--HQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEII
                                   .  .. |...||. .||.. .. .   .   .|..|.|...  .|.||||.|||||...||||..
...................................ledieealrkaflaadeellelallrpelagsGtTavvalirgnklyvanvGDSravllrngelv

PMSREFTP--ETERQRLQLLGflkpellgsefthlefprrvlpkelgqrmlyrdqnmtgwaykkieledlrfplvcGEGKKARVMATIGVTRGLGDHSLK
..... .|  |.||.|.. .|                                                       |     ||. .. ||| |||..||
qltvdhkpvnelererilsag.......................................................gavshgrvngvlavtRalGdfdlk

VCSSTLPIKPFLSCFPEVRVYDLTqyeHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSayepnDHSRYTALAQALVLGARGtprdrgwrlpnnkLGSGD
.. | |...|..|..|.|.|..||   . .||.|.|..|||||| .. |... | ..|.      .  ....|..||  |                || |
lllslllleplvsaePdvtvlelt...ledddfllLasDGlwdvlsneeivdivrslla.....kgldleeaaeeLvdlAla.............rgsrD

DISVFVIPLGGP
.|.|.|. |.|.
NiTvvvvrlngl
PP2Cc_SM00332 98-496 6.4e-43 140.1 In-house 5-274 (274) alignment 
Range on Protein: 98-496
Range on HMM: 5-274/274.0
GRRLPWSTGYaeVINAGKSRHNEDQACCEVVYVegrrsvtgvprepsrgQGLCFYYWGLFDGHAGGGAAEMASRLLHRHIREQLKDLVEILqdpsppplc
|..| .| |.    . |. . .||. .. | .|                .   . . |.||||.|  .|...|. |.... |.||   . |         
gsnlglsygk..ssmqgwrksmeDahvvvvdlv................eeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel.........

lpttpgtpdssdpshllgpqscwssqkevshESLVVGAVENAFQLMDEQMARERRGHQV---EGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEIIPMS
                               |. |  | ..||. .||..  | . ..      |..|.|...  ...||||.|||||...|||.....|
...............................eddveealkkaflstdeeileeeqskelenalsGstavvallkkedlyvanvGDSravlcrngkavqls

REFTP--ETERQRLQLLGFlkpellgsefthlefprrvlpkelgqrmlyrdqnmtgwaykkieledlrfplvcgEGKKARVMATIGVTRGLGDHSLKVCS
.. .|  |.||.|..  |                                                          .| ||  .. |.| .||| ||  .
vdhkpedederkRikkagg.......................................................vvekgrvngglavsrafGdhflkknk

stLPIKPFLSCFPEVRVYDLtqyeHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYepnDHSRYTALAQALVLGARGTprdrgwrlpnnkLGSGDDIS
   . .|.... |.| | .|       |..|.| .|||||| .. ||  .| . |.      . .... |. |.  |. .             || |.|.
..klkepyitaepdvkvvtl....tsedeflilaSDGlwdvlsnqevvdivrkllakg...ktndpqeaaelldeeairr............ggseDniT

VFVI
|.|.
vvvv
0049733 PP2C-like 106-498 1.1e-37 122.6 In-house 4-233 (235) alignment 
Range on Protein: 106-498
Range on HMM: 4-233/235.0
GYAEVINAGK-SRHNEDQACCevvyvegrrsvtgvprepsrgqglCFYYWGLFDGHAGGGAAEMASRLLHRHIREQLKDlvE--ILqdpsppplclpttp
... .   |.  ..|||  ..                         .......||| |. |.|.||.||.....|.|..                     
svgaasdigrvrkvneDavlv........................glllfavaDGhgghaagevasellvetllellle..lllld..............

gtpdssdpshllgpqscwssqkevsheslVVGAVENAFQLMDEQMARERRGH--QVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEIIPMSREFTP-
                             .. |...||. ..|.. .. . .     .|..|.|...  ||.||||.|||||...|.|........ .| 
.............................leealrkaflaaneallelalaspelagmgtTavvalldggklyvanvGDsrayllrdgklvqltedhspv

-ETERQRlqllgflkpellgsefthlefprrvlpkelgqrmlyrdqnmtgwaykkieledlrfplVCGEGKKARVMATIGVTRGLGDHSLKvcsstlpik
 |.||||                                                          .  .|   ||.  . .|| |||. ||         
nelerqr..........................................................iitaggavrvpgrlaltralGdlllk.........

pflscfpevrvYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATVDRvlsayepndhS---------RYTALAqalvlgargtprdrgwrlpnnkLGSGD
           .|.|..|  |.|.|.| .|||||| .| |..... .                      .|||                       |. |
...........pdvtvlelepgdflllasDGlwdvlsdeeivdllrs..........ldleeaaerlvelala......................rggrD

DISVFVIPL
.|.| |. |
NiTvvvvrl
subfamily_PPM1G2_pd Subfamily PPM1G2 153-304 3e-18 58.8 In-house 54-161 (287) alignment 
Range on Protein: 153-304
Range on HMM: 54-161/287.0
YWGLFDGHAGGGAAEMASRLLHRHIREqlkdlveilqdpsppplclpttpgtpdssdpshllgpqscwssQKEVShESLVVGAVENAFQLMDEQMARERR
....|||| |  .|..|.. |.. | .                                           .|. . |  .  ....||  .||.. ....
lfavfDGhGGakvakyagkklikkiak...........................................kksfk.egaleqilkdafletDeellkdek

GHQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEIIPMSREFTPETERQ
 .. . |. |.||.    |.||||||||||..  .|..  .|..  |..|  
lkdesaGstavvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeese
PPM_PTC7 220-305 7.6e-16 51.3 In-house 60-149 (259) alignment 
Range on Protein: 220-305
Range on HMM: 60-149/259.0
WSSQKEVSHESLVVGAVENAFQL--MDEQMAR--ERRgHQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEII-PMSREFTPETERQR
. ..|.     ..  |. ..|.   .|| . .  ... .   .|..|.|...   |.||||.|||||...|.|... .... ..|. |. |
lkerksfeeleklekalrksflaldtdeelksseant.epstsGstAvvalitgsklyvAnvGDSravLcrsgnavkqltedHkpsnedEr
subfamily_PPM1A_pd Subfamily PPM1A 153-306 9.2e-16 51.0 In-house 44-165 (282) alignment 
Range on Protein: 153-306
Range on HMM: 44-165/282.0
YWGLFDGHAGGGAAEMASRLLHRHIREqlkdlveilqdpsppplclpttpgtpdssdpshllgpQSCWS-SQKEVSHESLVVGAVENAFQLMDEQMARER
.. .||||||  .|..... |...| |                                     .. .. ...| |... |  |....|  .||.. .. 
fFavfDGHaGsevakyvkkhllenile.....................................eeelkeaaleasekdevkealrqgfLaldeairels

RGHQV--EGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEIIPMSREFTPET--ERQRL
. ..   . |. |..|.    ....||.|||||...|||. . ....  |..  |..|.
tdlktadksGsTavtvlvsekhliianlGDsRavlcrngkaaflteDHkpsrpkEkkRi
PP2C Protein phosphatase 2C 218-307 6.2e-15 48.4 Pfam-A 58-152 (255) alignment 
Range on Protein: 218-307
Range on HMM: 58-152/255.0
SCWSSQKEVSHESLVVGAVENAFQL-MDEQMAR--ERRgHQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEII-PMSREFTPE--TERQRLQ
 .. .||. .   .|  |. ..|.  .||....  ... ..   |..|.|...   |.||||.|||||...|.....  ...  .|.   ||.|..
eilkeqksflelekvekalrksfladtdeelksskant.epsksGstavvalirgkklyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIe
PP2C Protein phosphatase 2C 218-307 6.2e-15 48.4 In-house 58-152 (255) alignment 
Range on Protein: 218-307
Range on HMM: 58-152/255.0
SCWSSQKEVSHESLVVGAVENAFQL-MDEQMAR--ERRgHQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEII-PMSREFTPE--TERQRLQ
 .. .||. .   .|  |. ..|.  .||....  ... ..   |..|.|...   |.||||.|||||...|.....  ...  .|.   ||.|..
eilkeqksflelekvekalrksfladtdeelksskant.epsksGstavvalirgkklyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIe
subfamily_PPM1D_pd Subfamily PPM1D 152-472 9.5e-14 44.2 In-house 36-289 (309) alignment 
Range on Protein: 152-472
Range on HMM: 36-289/309.0
YYWGLFDGHAGGGAAEMASRLLHRHIREQLKDlveilqD------PsppplclpttpgtpdssdpshllgpqscwssqkevsheslvVGAVENAFQLMDE
 . ..|||| |  ||. |.. |   |..| |                                                        . |...||  . |
afvavfDGHGGkeAakfarehlwsvikkqkkf......lssepedv.........................................leAireaflathe

QMARE-------RRGHQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEiipmsreftPETERQRLQLLGFLKPELLGSEFTHLEFPRRVLPKELGQR
.| ..       ..|.    |  | |||    |.|||. |||....  . .          |.. .  .|    ||| .  .    |   .|  |.  .|
amkkkleeWpktksgllstaGttasvviirreklyvahvGDsaivlgvkep.........kekklrakeltkdHkPespeekerieelGGevaaksGvkR

MLYRDQNmtgwaykkieledlrfpL----VcgegKKARVMATIGVTRGLGD-HSLKVCSSTLPIKPflscFPEVRVYDLTQYEHcpdDVLVLGTDGLWDV
. .. ..                 |         ..   .  . |.| |||  | .  | .  . |     |.| |. |.. |.   ....|..||||.|
vvWkRpr.................lehngp....tvideiPFLavaRslGDlWsynaksgefvvsP....ePdvkvrtldpnee...kfiilasDGlwnv

TTDCEVAATVDRVLSAYEPNDHSRyTALAQALVLGARGT
 |  ..  .| .  .  | ....  .  |.|||  | ..
ltpedavsvvekeeekkelkeeqs.rsvakalvkealqr
subfamily_PPM1L_pd Subfamily PPM1L 153-306 1.4e-13 43.8 In-house 37-155 (269) alignment 
Range on Protein: 153-306
Range on HMM: 37-155/269.0
YWGLFDGHAGGGAAEMASRLLHRHIREQLKDLveilqdpsppplclpttpgtpdssdpshllgpQ-------ScwssqkeVSHESLVVGAVenafQLMDE
. ..|||| |  |||.|  .| . |...|..|                                .               .... |..  .      .||
ffavfdGhGGefaaefakdvlvkaiknkliel................................dadkentep.......infsklltdei....lsvde

QMARERRGHQVEGGCCALVVIYLLGKVYVANAGDSRAIIV-RNGEIIPMSREFTPETERQRL
..  . .  . . |. ||. .    .. ||| |||| ... ..|. ||.| .  |.  ..| 
kllekakraediaGttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerk
PPM_PTC7_SpoIIE 156-327 1.3e-12 41.0 In-house 39-152 (230) alignment 
Range on Protein: 156-327
Range on HMM: 39-152/230.0
LFDGHAGGGaaEMASRLLHRHIREQLKDLVEilqdpsppplclpttpgtpdssdpshllgpqscwssqkevshesLVVGAVENAFQLMDEQMARErrghQ
 .||| |.    .|..||.  .||. .   |                                            ..  .......... ..  |     
dvdGhGgra..alamgllrtalrelafagle............................................kpeeilrrlnlalaadlede....p

VEGGCCALVVIYLLGK--VYVANAGDSRAIIVRNGEIipmsreftpetERQRLQLLGFL-KPELLGSEFTHLEFP
 ..|..|.|...   .  .||||||||....||...            || |... |..    | |..|  |...
sssgaTavvalidpstgklyvanaGdsppllvrddgg...........ererivagglpslGilpgrvfgvlavs
subfamily_PPM1A_pd Subfamily PPM1A 369-451 5.5e-12 38.6 In-house 173-251 (282) alignment 
Range on Protein: 369-451
Range on HMM: 173-251/282.0
KKARVMATIGVTRGLGDHSLKVCSSTLPIKPFLSCFPEVRVYDLTQYehcpDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYE
 . ||. .. |.| |||...|  ..  . .  .|  |||.. . ..     || |||  ||.|||..| ||.. | . |.. .
vvsRvnGaLAvsRalGDyeykeeeekkaeeqlvsaepevtsiersee....ddflvlacDGiwDvlsdeevvelvrkrlevad
PP2C_SIG_SM00331 156-496 7.3e-12 38.3 In-house 35-215 (217) alignment 
Range on Protein: 156-496
Range on HMM: 35-215/217.0
LFDGHAGGGAAEMASRLLHRHIREQLKDLveilqdpsppplclpttpgtpdssdpshllgpqscwssqkevsheslvvG----AVENAFQLMDEQmarer
..||. .| ||..||. |.  .||.|..                                                       |.... ....|.     
vaDgmGkGlaAaaassqlrtalrellseg.................................................eelsqalkrlnraiyee.....

rgHQVEGGCCALVVI---YLLGKVYVANAGDSRAIIVR-NGEIIPMSReftpeterqrlqllgflkpellgsefthlefprrvlpkelgqrmlyrdqnmt
  ....|. ..|...   .  ||...||||||| ...| .... . .                                                     
..keekgmfaTlllalydfssgklsyanaGdsrpyllrdgklveilkd....................................................

gwaykkieledlrfplvcgegkkarvmatigvtrglgdhslkvcsstlPIKPFLSCFPEVRvYDLTQYEHCPDDVLVLGTDGLWDVTTDCE-VAATVDRV
                                                .  . |.  |||. .| .. |  ..|.|.| ||||... .. .   ... ..
................................................vegaplGlepevs.vdirelelekgdllllytDGltearsekgfaeerleei

LSAYEpndHSRYTALAQ----ALVLGARGTPRdrgwrlpnnklgsGDDISVFVI
| ..    .|   .|||     |.  |.| .               |||.| |.
ledlv...dseaqelaqkiveellelakgsng.............eDdiTvvvv
subfamily_PPM1G_pd Subfamily PPM1G 237-305 3e-11 36.0 In-house 277-345 (473) alignment 
Range on Protein: 237-305
Range on HMM: 277-345/473.0
ENAFQLMDEQMARERRGHqvEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEIIPMSREFTPETER--QR
|.| . .| .  .|  |.  . |. | |..    |..||||||||... |||. . .| .  || |   .|
eeakeeldgseekeepGe..dsGttAvvaLlkekklivAnaGDsRcvlsrnGkAldlslDHkPeDevEleR
subfamily_PPM1E_pd Subfamily PPM1E 223-305 4.1e-11 35.6 In-house 69-151 (265) alignment 
Range on Protein: 223-305
Range on HMM: 69-151/265.0
QKEVSHESLvvGAVENAFQLMDEQMARERRGHQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEIIPMSREFTPETER--QR
|... ....   |...||.|.||.. .     ....|. | ||.    ..|||  |||.|..||.||.. . .   || |.  .|
qeklkedpa..ealkeafkltDerflqkaereklksGstavvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkR
PP2C Protein phosphatase 2C 370-453 7.6e-11 35.1 Pfam-A 161-236 (255) alignment 
Range on Protein: 370-453
Range on HMM: 161-236/255.0
KARVMATIGVTRGLGDHSLKVCSstlpiKPFLSCFPEVRVYDLTQyehCpDDVLVLGTDGLWDVTTDCEVAATVDRVLSAY-EPN
. ||  .. |.| |||. ||  .     ... |. |.|.. .||.     |. |.|..|||||| .| |..  | . ||.  .|.
ngrvngsLavsRalGdfelkpke.....eqlvsaePdvtsvklte...e.defliLasdGlwdvlsdqeavdlvrselskkkspm
PP2C Protein phosphatase 2C 370-453 7.6e-11 35.1 In-house 161-236 (255) alignment 
Range on Protein: 370-453
Range on HMM: 161-236/255.0
KARVMATIGVTRGLGDHSLKVCSstlpiKPFLSCFPEVRVYDLTQyehCpDDVLVLGTDGLWDVTTDCEVAATVDRVLSAY-EPN
. ||  .. |.| |||. ||  .     ... |. |.|.. .||.     |. |.|..|||||| .| |..  | . ||.  .|.
ngrvngsLavsRalGdfelkpke.....eqlvsaePdvtsvklte...e.defliLasdGlwdvlsdqeavdlvrselskkkspm
subfamily_PDP_pd Subfamily PDP 154-287 1.4e-09 30.6 In-house 28-181 (398) alignment 
Range on Protein: 154-287
Range on HMM: 28-181/398.0
WGLFDGHAGGGAAEMASRLLHRHIREQL---KDLVEILQDPSPPPLCL-------PTTPGTPDSSDPSHLLGPQSCWSSQKEVSHEsLVVGAVENAFQLM
 |.||||.|  .||  |. | ...  .|   ..|.|...  .    .|        ..  . |.. . .|   .. . .. |.. |  |  |...||. .
fgvfDGHggaacaeavskrLlkyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslselskylqelleaeve.kvkealkkaFlkl

DEQMARERR----GHQVE-------GGCCALVVIYLLGKVYVANAGDSRAIIVRN
|.... |      .....        | |||.. .   ...|||.||.||.. ..
DkdistealkklkekslreallvalsGacallaliegtelhvAntGDcravlgvq
PPM_PTC7 370-456 1.8e-09 30.4 In-house 164-243 (259) alignment 
Range on Protein: 370-456
Range on HMM: 164-243/259.0
KARVMATIGVTRGLGDHSLKVCSStlpIKPFLSCFPEVRvydLTQYEHCpDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYEPNDHS
. ||  .. |.| .||. ||   .    .. .|. |..     |. .   |. |.|..|||||| .| |..  | ..||. .|.. .
ngrvngvlavsRafGdfelkpket...eeqlvsaePdis...stkidee.defliLasdGlwdvvsdqeavdlvrselskkdpmeaa
subfamily_PPM1G2_pd Subfamily PPM1G2 369-448 3.5e-09 29.0 In-house 173-248 (287) alignment 
Range on Protein: 369-448
Range on HMM: 173-248/287.0
KKARVMATIGVTRGLGDHSLKVCSSTLPIKPFLSCFPEVRVYDLTqyEHcpDDVLVLGTDGLWDVTTDCEVAATVDRVLS
.  ||  .. . | |||.. | .... |      ..|.| | .|.  |.  |. |||  ||.||| |. ||   |   |.
elnrvngnLalsralgDfefkknvkkkpeeqivtavPDvlvkkld..ed..deflvLaCDGiWDvltnkevvdlvrerlv
PPM_PTC7_SpoIIE_motif 410-496 3.1e-08 27.2 In-house 2-78 (81) alignment 
Range on Protein: 410-496
Range on HMM: 2-78/81.0
YDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYEPNDHSRYTALAQALVLGARGtprdrgwrlpNNKLGSGDDISVFVI
|| ....  |.|||.|.||||..  .. .   .....|.. . ... .   ||..||  ..           |.. .. |||...|.
ydeaefqLkpgdvllLyTDGltEardsdgelfgkeellrladraegkslqeladklvdevle..........ngsgereDDitllvl
subfamily_PP2D1_pd Subfamily PP2D1 365-451 1.2e-07 23.8 In-house 234-310 (492) alignment 
Range on Protein: 365-451
Range on HMM: 234-310/492.0
CGEGKKARVMATIGVTRGLGDHSLKVCSSTLPIKPFLSCfpevrvYDLTQYehcpDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYE
  ..|...|   ...||||| .      ... ..| . .        |..     . .||| . |||.| .. ||.. |  .|  |.
vkseknglvnGildttRGLGnyGdpkLkksvipePktts......vkldea....aqflvlAsnGlWevlseeevlsLvkqtlaiyk
subfamily_TAB1_pd Subfamily TAB1 254-287 1.3e-07 23.8 In-house 125-158 (333) alignment 
Range on Protein: 254-287
Range on HMM: 125-158/333.0
HQVEGGCCALVVIYLLGKVYVANAGDSRAIIVRN
... ||  |.|.. .  |.||||.|||||..|..
eeisgGttAvvalifnnkLyVaNvGdsrAllvkr
subfamily_PPM1K_pd Subfamily PPM1K 236-306 1.5e-07 23.8 In-house 71-149 (263) alignment 
Range on Protein: 236-306
Range on HMM: 71-149/263.0
VENAFQLMDEQMARERRGH-----QVEGGCCALVVIYLLGK-VYVANAGDSRAIIVRNGEIIPMSREFTPET--ERQRL
. |||. .|... |  . .     . . |  | |..   |. . .|. ||||||. |||.   ..|. .||   |..|.
lknafeeldkklkrylefsvaeaellssGttatvsllrdGtelvlaslGdsrailcrnGkakkltrdhdPeleeekeri
subfamily_PPM1G_pd Subfamily PPM1G 371-449 3.3e-07 22.6 In-house 357-431 (473) alignment 
Range on Protein: 371-449
Range on HMM: 357-431/473.0
ARVMATIGVTRGLGDHSLKVCSsTLPIK-PFLSCFPEVRVYDLTQYehcpDDVLVLGTDGLWDVTTDCEVAATVDRVLSA
 ||   . . | ||||. |  . .|| |   .| .|...|  ||.     |. ||| .||.|.| .  ||   |   |. 
gRvnGGLnlsRAlGDhaYkkne.eLplkeqmisAlPDikvltltee....deFlvlAcDGiWnvmesqevvdfvraklkk
subfamily_PPM1E_pd Subfamily PPM1E 371-469 5.4e-07 22.1 In-house 165-246 (265) alignment 
Range on Protein: 371-469
Range on HMM: 165-246/265.0
ARVMATIGVTRGLGDHSLkvcsstlpiKPFLSCFPEVRVYDLTQYEhcpdDVLVLGTDGLWDVTTDCEVAATVDRVLSAyepnDHSRYTALAQALVLGA
 ||  .. |.| .|| .|         ||..|  ..|  ..|.. |    ..|.|..|||||| .. ||  .|.  |.     ... .. .|. ||  |
wRvnGvLsvsRaiGDvkl.........kpyvsgeadvaeveldgse....eylilacDGlwDvvneeevvklveeflad....gaedlsevakllveaa
subfamily_PP2D1_pd Subfamily PP2D1 264-306 7.4e-07 21.2 In-house 182-226 (492) alignment 
Range on Protein: 264-306
Range on HMM: 182-226/492.0
VVIYLLGKVYVANAGDSRAIIVRNGEIIPMSREFTPETER--QRL
|    || .|.||||. .|...|.|. | . || ||. ..  .|.
vhleelgvlyianaGnvqAvLcreGkaiiLtreHtprnkkERtRv
subfamily_PDP_pd Subfamily PDP 399-451 9.7e-07 21.2 In-house 268-316 (398) alignment 
Range on Protein: 399-451
Range on HMM: 268-316/398.0
PFLSCFPEVRVYDLTQYehcpDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYE
|.|.  |||  . |..     |  |||.||||||. .. ||. .| . |.  .
PYltaePevtshklren....dkFLvlatDGLwdllsneevvslVgehlakkk
subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 225-309 9.9e-07 21.6 In-house 57-144 (292) alignment 
Range on Protein: 225-309
Range on HMM: 57-144/292.0
EVSHESLVVGAVENAFQLMDEQMARERRGHqvEGGCCALVViylLG-KVYVANAGDSRAIIVR-----NGEIIPMSREFTPE--TERQRLQLL
    |.|. . .. | .| .  .    ..       || |     . ....|| |||||.. |     . |.||.||.  ||   ||.|..  
qelsealllrildiaakldkltidaresat..tavvcarvr...ddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilra
subfamily_ILKAP_pd Subfamily ILKAP 234-307 2.5e-06 19.8 In-house 87-170 (293) alignment 
Range on Protein: 234-307
Range on HMM: 87-170/293.0
GAVENAFQLMDEQMARERRGH--QVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNGE------IIPMSREFTPE--TERQRLQ
 .. ..|.  ||.. .. . .  .   |. | ||. |   .|||| |||.|..||. |       ...... ||    ||.|.|
kclvdsfkktdeefLklaskakPvWkdGstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriq
SpoIIE Stage II sporulation protein E (SpoIIE) 399-496 4.6e-06 18.6 Pfam-A 104-190 (193) alignment 
Range on Protein: 399-496
Range on HMM: 104-190/193.0
PFLSCFPEvRVYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYEPNDHSRYTALAQALVLGARGtprdrgwrlpNNKLGSGDDISVFVI
. |. .|| . |. ....  |.|.|.| |||. .  .. .     .| |.. . . ... ..|..|||  ..           ... .  |||...|.
lplGilpe.adyeeaelqlepgdllllyTDGvtEardpdgelfgkerllallaeaegesleelldalveelle..........lgsgeleDDitllvl
SpoIIE Stage II sporulation protein E (SpoIIE) 399-496 4.6e-06 18.6 In-house 104-190 (193) alignment 
Range on Protein: 399-496
Range on HMM: 104-190/193.0
PFLSCFPEvRVYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYEPNDHSRYTALAQALVLGARGtprdrgwrlpNNKLGSGDDISVFVI
. |. .|| . |. ....  |.|.|.| |||. .  .. .     .| |.. . . ... ..|..|||  ..           ... .  |||...|.
lplGilpe.adyeeaelqlepgdllllyTDGvtEardpdgelfgkerllallaeaegesleelldalveelle..........lgsgeleDDitllvl