Gene TAB1 in Homo sapiens

Synonym: 3'-Tab1, MAP3K7IP1, RP3-407F17.2, TAB1

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily TAB1
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP187_AA protein Get Run
HsapP187_AA_29-365 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_TAB1_pd Subfamily TAB1 31-366 8.1e-152 497.8 In-house 1-332 (333) alignment 
Range on Protein: 31-366
Range on HMM: 1-332/333.0
SASNRSYSadgkgTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKAS
|.|||.||     .|.|. ||....|..||...||.||.|||||....||.|||.|||||.||..|.|||.|..||..||. |||.||||||||||||..
svsnrrys.....kedhevedkvflfktendpilyavFdGydGnkaakfveqrLvaellleqltdelaeaevkevlkrafeeverkflesiddalaekdd

LQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVdGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQ
|||||||||....|  ||.. .|||..||.|||||..||||...||||||||||..||||.|...   .|.||.|||||.|||||.||..||||. .||.
lqsqlPegvssyeleeqypekierlqeleeeisgGttAvvalifnnkLyVaNvGdsrAllvkrke.sekvkqLsvdHttdNedEllRlkdLGldieqikr

VGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQE-IAAMIDTEFAKQTSLDAVAQA
.......|.||.|||||||.||.|.|.||.||..|.||||.|.||.|.|..|.||||||.|.||.||...||...|.| |.....||..||..|..||||
nkrlgskentRsiGdykvkkgykdvdilssakgePviaePdiqgaypiddityflvlmSdGvyktLeevtgpetsnvenillevitelekqatlqdvAqa

VVDRVKRIHSDTFASGG-ERARFCPRHEDMTLLVRNFG
|||.|||.|.|...|.. |||..|....||||||..|.
vvdkvkrkHkdaylssaseravicrkrddmtllvlkfe
PPM_PTC7 70-333 3.4e-43 141.0 In-house 2-258 (259) alignment 
Range on Protein: 70-333
Range on HMM: 2-258/259.0
GYDGNRVTNFVAQRLSAELLLGQLNAEhaEADVRRVLLQAFDVVERSFLESIDDALAE-KASLQSQLPEG-VPQHQLPPQYQK--ILERLKT-LER--EI
......  .|  . . |...| .|...  . .  . ... || .  . .. . .  .| .. ......|.  ....|  ....  . |.||.  ..  ..
dggasafqgfrksmedahialanless..sgkdsvaffavfdghggreaakyarehleeilkerksfeeleklekalrksflaldtdeelksseanteps

SGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGlqvTQLNVDHTTENEDELFRLSQLGLDAGKIkQVGIICGQ-ESTRRIGDYKVKYGYTdidllsaa
..|..||||.. ..||||||||. ||.||.|  .    .||..||...||||  |....|    .. ..| ..|. . .| .||.. | ..|        
tsGstAvvalitgsklyvAnvGDSravLcrsgnav...kqltedHkpsnedEreRiegaggsvsnv.gngrvngvlavsRafGdfelkpket........

KSKPIIAEPEIHGAQPLDGvTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDR
......|||.|. ..  .  . ||.|.|.||.  ..  .    ...|....  .|.|...  .|.|....| 
eeqlvsaePdisstkidee.defliLasdGlwdvvsdqeavdlvrselskkdpmeaaeklvdeaiargsedn
PP2C Protein phosphatase 2C 70-333 7.2e-42 136.7 Pfam-A 2-254 (255) alignment 
Range on Protein: 70-333
Range on HMM: 2-254/255.0
GYDGNRVTNFVAQRLSAELLLGQLNAEhaEADVRRVLLQAFDVVERSFLESIDDALAE-KASLQSQLPEG-VPQHQLPPQYQK-ILERLKT-LER--EIS
..........  . . |...| .|...  ... .. ... || .  . .. ...  .| .. .|....|.   ...|  .... . |.||.  ..  ...
dvgaselqgarksmedahialknleks..sgkssvaffavfdghggreaakyarehleeilkeqksflelekvekalrksfladtdeelksskantepsk

GGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGlqvTQLNVDHTTENEDELFRLSQLGLDAGKikqVGIICGQ-ESTRRIGDYKVKYGYtdidllsaak
 |..||||.. ..||||||||..||.||... .    ..|..||....|||  |....|    .   .| ..|. . .| .||...| ..          
sGstavvalirgkklyvAnvGDSravLcrkdnak...keltedHkpsdedEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpke..........

SKPIIAEPEIHGAQPLDGvTGFLVLMSEGLYKALEAAHGPGQANQEIAAM-IDTEFAKQTSLDAVAQAVVDR
.....|||... ..  .  . ||.|.|.||.  |.  .    ...|. ..   .|.|...  .|.|... |.
eqlvsaePdvtsvkltee.defliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaiargsedn
PP2C Protein phosphatase 2C 70-333 7.2e-42 136.7 In-house 2-254 (255) alignment 
Range on Protein: 70-333
Range on HMM: 2-254/255.0
GYDGNRVTNFVAQRLSAELLLGQLNAEhaEADVRRVLLQAFDVVERSFLESIDDALAE-KASLQSQLPEG-VPQHQLPPQYQK-ILERLKT-LER--EIS
..........  . . |...| .|...  ... .. ... || .  . .. ...  .| .. .|....|.   ...|  .... . |.||.  ..  ...
dvgaselqgarksmedahialknleks..sgkssvaffavfdghggreaakyarehleeilkeqksflelekvekalrksfladtdeelksskantepsk

GGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGlqvTQLNVDHTTENEDELFRLSQLGLDAGKikqVGIICGQ-ESTRRIGDYKVKYGYtdidllsaak
 |..||||.. ..||||||||..||.||... .    ..|..||....|||  |....|    .   .| ..|. . .| .||...| ..          
sGstavvalirgkklyvAnvGDSravLcrkdnak...keltedHkpsdedEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpke..........

SKPIIAEPEIHGAQPLDGvTGFLVLMSEGLYKALEAAHGPGQANQEIAAM-IDTEFAKQTSLDAVAQAVVDR
.....|||... ..  .  . ||.|.|.||.  |.  .    ...|. ..   .|.|...  .|.|... |.
eqlvsaePdvtsvkltee.defliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaiargsedn
0034914 PP2C-like 32-365 6.9e-37 120.0 In-house 19-290 (295) alignment 
Range on Protein: 32-365
Range on HMM: 19-290/295.0
ASNRSYSADGKGTeSHPPEDSWLKFRS----ENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLG----QLNAEHAEADVRRVLLQAFDVVERSFLESIDD
 . |...|. .|  ... ||..| ...    .....|.|||.|. | .. ......|  .||      .|.... . |....| .||  ... .|| . .
lllrvgvasdqGr.rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelall

AlaekaslqsqlpegvpqhqlppqyqkilerlktlEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTvdglQVTQLNVDHTTENEDELFRLSQLGL
                                    . . .|. ||||.. .|||||||||  ||.|...     ...||.|||.  ||.|  |. ..| 
r..................................pelagsGtTavvalirgnklyvanvGDSravllrng....elvqltvdhkpvnelererilsagg

dagkIKQVGIICGQ-ESTRRIGDYKVKYGYTDidllsAAKSKPIIAEPEIHgAQPLD-GVTGFLVLMSEGLYKALEaahgpgqaNQEIAAMIDTEFAKQT
    . . | ..|.   || .||.  |. ...      ... ...|||...  ..|. .   ||.|.|.||.. |.        |.||.... . .||..
....avshgrvngvlavtRalGdfdlklllsl.....llleplvsaePdvt.vleltledddfllLasDGlwdvls........neeivdivrsllakgl

SLDAVAQAVVDRVKRihsdtfasggerarfCPRHEDMTLLVRNF
.|...|...||.. .               .  ....| .|  .
dleeaaeeLvdlAla...............rgsrDNiTvvvvrl
PP2Cc_SM00332 30-332 3.7e-33 108.1 In-house 5-257 (274) alignment 
Range on Protein: 30-332
Range on HMM: 5-257/274.0
GSASNRSYSADGKGTESHPPEDSWLKFRS---ENNCFLYGVFNGYDGNRVTNFVAQRLSaELLLGQLNAEHA--EADVRRVLLQAFDVVERSFLESIDDA
|| .. ||. . . .. .. || .    .   |..  ..||| |  |..| .||...|  | |  .|. .    | || ..| .||  ..  .||. .  
gsnlglsygkssmqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklp.ealkeelkkkkdeleddveealkkaflstdeeileeeqsk

LAEKaslqsqlpegvpqhqlppqyqkilerlktlereISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVdglqVTQLNVDHTTENEDELFRLSQLGLd
. |.                                  . |..||||.| ...|||||||  || ||..      ..|| |||..|.|||. |... |  
elen.................................alsGstavvallkkedlyvanvGDSravlcrngk....avqlsvdhkpedederkRikkagg.

agKIKQVGIICGQESTRRIGDYKVKYGYtdidllsAAKSKPIIAEPEIHGAQPlDGVTGFLVLMSEGLYKaleaahgpGQANQEIAAMIDTEFAKQ--TS
  ....  . .|....| .||...|            |.. |.|||...  .  .  . ||.|.| ||.            |||.  ..    ||.   .
..vvekgrvngglavsrafGdhflkknk.......klkepyitaepdvkvvtl.tsedeflilaSDGlwd........vlsnqevvdivrkllakgktnd

LDAVAQAVVD
 ...|. ...
pqeaaellde
subfamily_PPM1A_pd Subfamily PPM1A 54-334 7.7e-21 67.7 In-house 34-264 (282) alignment 
Range on Protein: 54-334
Range on HMM: 34-264/282.0
LKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLL-GQLNAEHAEADVRRVLLQafdVVERSFLEsIDDALAEKASLQSQLPEGvpqhqlppqyqkil
 .. . ..  .. || |  |..|...|.. | ...|   .|.....||. .. ...   .....||. .|.|. |. . ...  .               
aslgalkdwsfFavfDGHaGsevakyvkkhllenileeeelkeaaleasekdevke...alrqgfLa.ldeairelstdlktadks..............

erlktlereisgGAMAVVAVLLNNKLYVANVGTNRALLCKSTvdglQVTQLNVDHTTENEDELFRLSQLGldaGKIKqVGIICGQ-ESTRRIGDYKVKYG
            |. ||.... ...|..||.|  ||.||. .    ... |  ||  ....|  |..| |   |..  |. ..|.   .| .|||..|  
............GsTavtvlvsekhliianlGDsRavlcrng....kaaflteDHkpsrpkEkkRieqAG...Gsvv.vsRvnGaLAvsRalGDyeykee

YTdidllSAAKSKPIIAEPEIHGAQPLDGVTgFLVLMSEGLYKALEaahgpgqaNQEIAAMIDTEFAKQTSLDAVAQAVVDRV
 .       |... ..||||..  .  .  . |||| ..|..  |.        ..|..... ... ... | .||.|.||. 
ee.....kkaeeqlvsaepevtsierseedd.flvlacDGiwDvls........deevvelvrkrlevadeleevakalvdka
subfamily_PPM1G2_pd Subfamily PPM1G2 45-334 3e-20 65.3 In-house 35-264 (287) alignment 
Range on Protein: 45-334
Range on HMM: 35-264/287.0
ESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRlsaelllgqlnaehaeadvrrvllqafdvversflesIDDALAEKASLQSQLPEGVPQHQL
..|  |.  |. . .... |..||.|. |..|.......                                     .   .|.| |....  | . .. .
DahilenelleksddkslalfavfDGhGGakvakyagkk.....................................likkiakkksfkegaleqilkdaf

PPQYQKILERlKTLEREISgGAMAVVAVLLNNKLYVANVGTNRALLCKSTvdglQVTQLNVDHTTENEDELFRLSQlgldAGKIKQVGIICGQES-TRRI
  . ...|.  ..|. | . |. |||... ..||||||.|  ||.|....    .| .| .||  ..|.|  |. .    || . ... ..|. .  | .
letDeellkd.eklkdesa.GstavvvlikeeklyvanaGDsravlsskg....nvkalsfDhkPqeesekkriia....agGfvelnrvngnLalsral

GDYKVKYGYTdidllSAAKSKPIIAEPEIHgAQPLDGVTGFLVLMSEGLYKALEaahgpgqaNQEIAAMIDTEFAKQTSLDAVAQAVVDRV
||.. | . .       .. . . |.|..   . ||  . ||||  .|..  |.        |.|.  .. ........||.... ..|. 
gDfefkknvk.....kkpeeqivtavPDvl.vkkldeddeflvLaCDGiWDvlt........nkevvdlvrerlvsgakldeiieelldkc
0049733 PP2C-like 43-362 4.8e-19 61.8 In-house 12-230 (235) alignment 
Range on Protein: 43-362
Range on HMM: 12-230/235.0
GTESHPPEDSWLKfrsenNCFLYGVFNGYDGNRVTNFVAQRLSAELLlgQLNAEHAEADVRRVLLQAFDVVERSFLESiddalaekaslqsqlpegvpqh
|   .  ||..|      ...|..|..|  | .. ......|   ||  .| .|. . |....| .||  ... .||                       
grvrkvneDavlv.....glllfavaDGhgghaagevasellvetll..elllelllldleealrkaflaaneallel......................

qlppqyqkilerLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKstvDGlQVTQLNVDHTTENEDELFRLSQLGLDAgkikqvGIICGQESTRR
             .. .    .|. ||||.| ..||||||||  ||.|..   || ...||..||.  ||.|  |. ..|          .. .   || 
............alaspelagmgtTavvalldggklyvanvGDsrayllr...dg.klvqltedhspvnelerqriitaggav......rvpgrlaltra

IGDYKVKygytdidllsaakskpiiaePEIHGAQPLDGVtgFLVLMSEGLYKAleaahgpgQANQEIAAMIDTefakqTSLDAVAQAVVDRVKRihsdtf
.||. .|                    |...  .  .|   ||.|.|.||..           ..||.... .     ..|...|...|... .      
lGdlllk....................pdvtvlelepgd..flllasDGlwdv........lsdeeivdllrs.....ldleeaaerlvelala......

asggerarfCPRHEDMTLLV
            ....|..|
.........rggrDNiTvvv
PPM_PTC7_SpoIIE 125-333 9.8e-17 54.5 In-house 61-229 (230) alignment 
Range on Protein: 125-333
Range on HMM: 61-229/230.0
LAeKASLQsqlpegVPQHQLPPQYQKILERLKTLerEISGGAMAVVAVLLNNK--LYVANVGTNRALLCKStVDGlqvtqlnvdhttenedELFRLsQLG
|| .|.|.       |   |   ....  .|..   ..|.|| ||||.. ...  |||||.| ...||...  .|                | .|. ..|
la.fagle......kpeeilrrlnlalaadlede..psssgaTavvalidpstgklyvanaGdsppllvrd.dgg................ereri.vag

LDAGkI-KQVGIICGQ-ESTRRIGDYKVKYgytdidllsaaKSKPIIAEPEiHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMidteFAKQ
  .  .    | . |. . .. .||. ..|           . . . |||. . .  |.|.. ||.|.|.||.  |....   .. .|. .     .|..
glps.lGilpgrvfgvlavslapGdlllly...........tDGvveaepd.tsdgelfgkdeflilasdglwdvlspqelvdlvrdelekp....aaeg

TSLDAVAQAVVDR
   |.....||..
lleDDitllvvrv
subfamily_PDP_pd Subfamily PDP 157-299 3.8e-16 52.2 In-house 146-302 (398) alignment 
Range on Protein: 157-299
Range on HMM: 146-302/398.0
TLEREISgGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDG-LQVTQLNVDHTTENEDELFRLSQLGLDAGK---IKQVGIICGQESTRRIGDYKVKYGY
.|.  .| ||.|..|.. ...|.|||.|  ||.|...  .|  ....|. |.|..||.|. |. .   .  .   |..  ..     .|  ||.. |.  
allvals.GacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwse

-TDIDLLSA---AKSKP--------IIAEPEIHGAqPLDGVTGFLVLMSEGLYKALEAA
 ..  .|.      ..|        ..||||.  . .|   . |||| . ||.  |.  
elqkkvlekaylkvlepkdyktPPYltaePevtsh.klrendkFLvlatDGLwdllsne
subfamily_PPM1G_pd Subfamily PPM1G 163-298 3.4e-13 42.4 In-house 295-418 (473) alignment 
Range on Protein: 163-298
Range on HMM: 295-418/473.0
SGGAMAVVAVLLNNKLYVANVGTNRALLCKStvdGlQVTQLNVDHTTENEDELFRLSQLGldaGKIKQVGI-ICGQESTRRIGDYKVKYGYTdidlLsAA
. |. ||||.| ..||.|||.|  |. |...   | .  .| .||  |.| || |. . |   ||... |    |    | .||.  |   .    |  .
dsGttAvvaLlkekklivAnaGDsRcvlsrn...G.kAldlslDHkPeDevEleRiekAG...GkvdedgRvnGGLnlsRAlGDhaYkknee....L.pl

KSKPIIAEPEIHGAQpLDGVTGFLVLMSEGLYKALEA
| . | | |.|. .. |     |||| ..|.. ..|.
keqmisAlPDikvlt.lteedeFlvlAcDGiWnvmes
subfamily_ILKAP_pd Subfamily ILKAP 164-300 6e-12 38.3 In-house 113-234 (293) alignment 
Range on Protein: 164-300
Range on HMM: 113-234/293.0
GGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGL--QVTQLNVDHTTENEDELFRLSQLGldaGKIKQVGIICGQESTRRIGDYKVkygytdidllsaa
 |. |.| . |.| |||||.|  .|.|..   .|   .. .| .|||. ...|  |. . |   |....  .    | .| ||| .              
dGstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaG...gvvrdgrvlGvlevsrsiGdgrf.............

KSKPIIAEPEIHGAQpLDGVTGFLVLMSEGLYKALEAAH
|.  .|. |...  . |.    |.||  .||.|...| .
krlGvistPdvkkce.LtendlfvvlaCdGLwkvfsade
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 106-297 1.3e-11 37.3 In-house 77-212 (255) alignment 
Range on Protein: 106-297
Range on HMM: 77-212/255.0
LLQAFDVVERSFlesiddalaekaslqsqlpegvpqhqlppqyqkilerlktLEREISGGAMAVVAVLLNNKLYVANVGTNRALLC-KSTVdglqVTQLN
| .|.  ..  .                                         || .  |. |........| |.||||  |..|| | ..     ..| 
lkkaykeistqi........................................serpkfiGttaasvliiedkvyianvGdsrvvlcqkdgt....akrls

VDHTTENEDELFRLSQLGldaGKIKQVgiicgQESTRRIGDYKVKYGYTDIDLlsaakSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALE
.||   .|.|  |.|.||   |.. .      . ..|  |   |     |. |     .  ....|.....        ||.|  .|..  . 
ldhkPseeseekriselG...Gtvvst.....vvtsrvnGtlavsralGdsfl.....ePfvvpdPdlsqsleiskkdkflilacdGiwdlis
subfamily_PPM1H_pd Subfamily PPM1H 62-220 1.4e-10 33.5 In-house 62-212 (404) alignment 
Range on Protein: 62-220
Range on HMM: 62-212/404.0
CFLYGVFNGYDGNRVTNFVAQRLsAELLLGQLNAEHA-EADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKIlERlKTLER
. ..|.|.|. |. ..   .. |  . |  .|..     ..  .   . .. ....  .| ..   ||   . .|  |   .      ..| .|    . 
layfglfDGhaGsgaalvaskll.hkhlkekledvlellleksaeeeenteesskespssvseiyeekeiskeeLviGalesaflemDeqi.ar.ereay

EISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTvdglQVTQLNVDHTTENEDElfRLSQ
.|.||  |.||..|..|||||| |  ||.|...     ....|  |.| | | .  || .
rikGGCtalvalvllgklYvanaGDsRailvrkd....eiiplsadftPeteRq..Rlqe
subfamily_PPM1L_pd Subfamily PPM1L 62-297 2.6e-10 33.0 In-house 35-224 (269) alignment 
Range on Protein: 62-297
Range on HMM: 35-224/269.0
CFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAehaeadvrrvllqafdvversflesidD-------AlaekaslqSQLpEGVPQHQLPPQYQKILER
  ...||.|. |.  ..|. ..|. ...   ..                            |                 .  . . ....    .|.||.
esffavfdGhGGefaaefakdvlvkaiknkliel...........................dadkentep........inf.sklltdeilsvdekllek

LKTLErEISgGAMAVVAVLLNNKLYVANVGTNRALLCKStvDGLQVtQLNVDHTTENEDELFRLSQLGLD---AGKIKQVGIICgqeSTRRIGDYKVKyg
.|. | .|. |. |..|.. ...| |||||  | .|.    .|  .  |  ||  ..  |  |. . |      |  .  |..     .| .||| .|  
akrae.dia.GttalialvqesdlivanvGdsrGvlydk..rGkai.plsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvla...tsralGdyplk..

ytdidllsaaKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALE
          . . .||.|.|   .  |    ||.| |.||. .. 
..........dknlviadpdiltfdlddhkpeflilasdGlwdtfs
subfamily_PPM1E_pd Subfamily PPM1E 157-336 2.9e-10 32.8 In-house 95-248 (265) alignment 
Range on Protein: 157-336
Range on HMM: 95-248/265.0
TLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTvdglQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKygytdid
. . .. .|. |||... ...|||| .|  .|||.. .    .. ||   |  |.|||  |. ..|    .| .  .      .| |||.| |       
aereklksGstavvvliekdqlyvaWlGDsqallvrkg....eavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklk.......

llsaaksKPIIAEPEIHgAQPLDGVTGFLVLMSEGLYKALEaahgpgqaNQEIAAMIDTEFAKQT-SLDAVAQAVVDRVKR
       . ...|...    .||| . .|.| ..||.  ..        ..|.  ...  .|... .|. ||. .|.  | 
.......pyvsgeadva.eveldgseeylilacDGlwDvvn........eeevvklveefladgaedlsevakllveaake
subfamily_PP2D1_pd Subfamily PP2D1 174-298 7.6e-10 31.1 In-house 186-295 (492) alignment 
Range on Protein: 174-298
Range on HMM: 186-295/492.0
LNNKLYVANVGTNRALLCKStvdGlQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQ-ESTRRIGDYkvkyGytDIDLlsaakSKPIIAEPEI
    ||.||.|  .|.||.    | .  .|  .||..|. |  |... |    | ...| . |. . || .| |    |  | .|      | .| ||..
elgvlyianaGnvqAvLcre...G.kaiiLtreHtprnkkERtRvekagsvvvkseknglvnGildttRGLGny....G..dpkL.....kksvipePkt

HGAqPLDGVTGFLVLMSEGLYKALEA
.   .||  . |||| | ||.. |..
tsv.kldeaaqflvlAsnGlWevlse
subfamily_PPM1K_pd Subfamily PPM1K 159-296 5.4e-08 25.3 In-house 93-216 (263) alignment 
Range on Protein: 159-296
Range on HMM: 93-216/263.0
EREISGGAMAVVAVLLN-NKLYVANVGTNRALLCKSTvdglQVTQLNVDHTTENEDELFRLSQLG--LDAGKIKQVGIICGQESTRRIGDykvkygytdI
. . | |. | |..| . ..| .|..|  ||.||.      . ..|  ||. | |.|  |. . |  ..   . .  .      || .||         .
aellssGttatvsllrdGtelvlaslGdsrailcrnG....kakkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtrslGd.........l

DLlsaaKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKAL
||    |.  .||.|| .  .   .   ||||...|.   .
dl....kryGviatPetkslkvdhaadsflvlitdgisfvv
subfamily_PPM1D_pd Subfamily PPM1D 164-224 1.3e-06 20.7 In-house 108-170 (309) alignment 
Range on Protein: 164-224
Range on HMM: 108-170/309.0
GGAMAVVAVLLNNKLYVANVGTNRALLCKSTV--DGLQVTQLNVDHTTENEDELFRLSQLGLD
 |. | | .. ..|||||.||  ...| ..    . |. ..| .||  |. .|  |. .|| .
aGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGe
subfamily_ILKAP_pd Subfamily ILKAP 64-120 4.5e-06 19.0 In-house 45-103 (293) alignment 
Range on Protein: 64-120
Range on HMM: 45-103/293.0
LYGVFNGYDGNRVTNFVAQRLSAELL--LGQLNAEHAEADVRRVLLQAFDVVERSFLES
 |.||.|. |.| ..|.|..|  ..|  | . .    | .... |...|  ... ||. 
yyavfdGhaGsrasefaaeklhkkileklpksdvsakekeikkclvdsfkktdeefLkl
PPM_PTC7_motif 286-333 4.5e-06 20.1 In-house 1-50 (51) alignment 
Range on Protein: 286-333
Range on HMM: 1-50/51.0
VLMSEGLYKALEAAHGPGQANQEIAAM--IDTEFAKQTSLDAVAQAVVDR
.|.| ||.  |.  .  ..........    .|.|...  .|.|....|.
iLAsDGLWDvlsdqeavdlvrdqlskkglspqeaAeklvdealargseDn
subfamily_Choan-PPM-1_pd Subfamily Choan-PPM-1 145-294 5.6e-06 17.8 In-house 115-267 (317) alignment 
Range on Protein: 145-294
Range on HMM: 115-267/317.0
PPQYQKILERLKTLEREISGGAMAVVAVLLNNKLY-VANVGTNRALLC------KSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQ
||.. . . |  .  | .  |. |||||....  . ||| |   ||.       .   |||.|  | | || . ..|  |. .   .|... . | .  .
pPkgyvcisrddvptrPldfGttavvavvvdethvvvanaGdaaalvllrdqaghedrdGlsvealsvrhtlrskaerarvaevlpgaahvtedgylail

ESTrrIGDYKVKYGYTD-IDLLsaaKSKPIIAEPEIHGA-QPLDGVTGFLVlMSEGLYK
. .  . .|...   .    ||   |   .||.||..    . | | . .| .|.|.  
dea..laayelqltkslGhkll...kraGviadPevrsrvldvdevfavvv.vsdGitd
subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 157-229 7.9e-06 18.6 In-house 78-149 (292) alignment 
Range on Protein: 157-229
Range on HMM: 78-149/292.0
TLEREISGGAMAVVAVLLNN-KLYVANVGTNRALLCK-STVDGLQVTQLNVDHTTENEDELFRLSQLGldaGKIK
|..   |... .| |.  .. .|..||||  |||| .       ..  |  ||  |. ||  |. . |   |...
tidaresattavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraG...Grve