Gene MbrePPM-Un-5 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PPM-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP122_AA protein Get Run
MbreP122_AA_118-440 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Choan-PPM-1_pd Subfamily Choan-PPM-1 126-442 1.3e-193 634.2 In-house 1-317 (317) alignment 
Range on Protein: 126-442
Range on HMM: 1-317/317.0
QHGSRHGKLNQDVPFCASFKQNGHRIAIAAVFDGHGLLGEIAAAMARDTMTALQPTFAWDSLLTQPEQGMREIFAQLDAAIVAAHDAPPAQYTYIGQSGS
.||||||||||||.|.||||..|||||.|||||||.|||||||||||||.|||.|...||||||.|||...||||.||||||||.|||||.|.|||||||
thgsrhgklnqdvyflasfklaGhrialaavfdGhsllGeiaaamardtltallPelvwdslltePeqllkeifarldaaivaaydapPaeyeyigqsGs

LDFRLEAHAIPELDPPSGYVCTSRDGVPPRPIDFGCTAVVAVVVDETHVVVGNAGDAAAFVLLRDQAGHEDRDGYSVEALSVQHTARSKAEQARVHETHP
||||||||||.|||||.||||.|||.||.||.|||.|||||||||||||||.|||||||.||||||||||||||.|||||||.||.|||||.|||.|..|
ldfrleahaiaeldpPkgyvcisrddvptrPldfGttavvavvvdethvvvanaGdaaalvllrdqaghedrdGlsvealsvrhtlrskaerarvaevlp

GAAHFTGDGYLAPLDPTLAQYELQLTRSLGHRLLKRAGVIADPEVRSQTWPVGEVHGVVACSDGITDELSGLDVLDRVLNAGTALEASEVLCQDAQDYCM
||||.|.|||||.||..||.||||||.||||.|||||||||||||||....|.||..||..||||||||..||||||||.|.||||||||||.|||||..
gaahvtedgylaildealaayelqltkslGhkllkraGviadPevrsrvldvdevfavvvvsdGitdelkrldvldrvlraataleasevlcddaqdyll

DETCIDDATAVVALFPA
|||.||||||||.|.|.
detsiddatavvlllpl
0034914 PP2C-like 124-441 2.3e-31 101.9 In-house 26-291 (295) alignment 
Range on Protein: 124-441
Range on HMM: 26-291/295.0
TSQHGSrhGKLNQDVPFCAS-FKQNGHRIAIAAVFDGHGllGEIAAAMARDTMTAL----QP--TFAWDSLLTQPEQGMREIFAQLDAAIVAAHDAPpaq
 |  |    | |.|  ..   .    . .....||||||  |  || .|....  |        .. ... |...|. .|..| ..| ....   .    
asdqGr..rksneDavlvvlnllslledlllfgvfDGhg..Ghaaaevasellvelllellekllllltlsledieealrkaflaadeellelallr...

ytyigqsgsldfrleahaipeldppsgyvctsrdgvpPRPIDFGCTAVVAVVvDETHVVVGNAGDAAAFVLlRDQaghedrdgySVEALSVQHTARSKAE
                                     |. .  |.|||||..  .....|.|.||  |..| |..          .. |.| |.  .  |
.....................................pelagsGtTavvali.rgnklyvanvGDSravll.rng.........elvqltvdhkpvnele

QARVHETHPGAAHftgdgylapldpTLAQYELQLTRSLGHRLLK--------RAGVIADPEVRSQTWPVGEVHGVVACSDGITDELSGLDVLDRVLN---
..|. . ..   |                  |..||.||.. ||        . .|.| |.|..... ... . .. .|||..| ||  ...| | .   
rerilsaggavsh............grvngvlavtRalGdfdlklllslllleplvsaePdvtvleltledddfllLasDGlwdvlsneeivdivrslla

-AGTALEASEVLCQDAQDycmdETCIDDATAVVALFP
   .. ||.| |.. | .      . |. |.||. ..
kgldleeaaeeLvdlAla....rgsrDNiTvvvvrln
PP2Cc_SM00332 133-437 1.1e-26 86.8 In-house 22-273 (274) alignment 
Range on Protein: 133-437
Range on HMM: 22-273/274.0
KLNQDVPFCASFKQNGHRIAIAAVFDGHGllGEIAAAMARDTMT-ALQPTFAWDSL--LTQPEQGMREIFAQLDAAIVAAHDAPPAQYtyigqsgsldfr
| ..|. ..    .. .. .. .||||||  |. .| .... .. ||. .  ...     ..|. ... | ..| .|... .    .             
ksmeDahvvvvdlveeedwlffgvfDGhg..Gsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen............

leahaipeldppsgyvctsrdgvpprpIDFGCTAVVAVVVDEThVVVGNAGDAAAFVLLRDQaghedrdgysVEALSVQHTARSKAEQARVHETHPgaah
                            . |.|||||....|. ..| |.||  |..   ..          . .|||.|..  . | .|... ..    
...........................alsGstavvallkked.lyvanvGDSravlcrngk..........avqlsvdhkpedederkRikkagg....

ftgdgylaPLDPTLAQYELQLTRSLGHRLLKR------AGVIADPEVRSQTWpVGEVHGVVACSDGITDELSGLDVLDRVLNAG------TALEASEVLC
               .  |...|..| . ||.       ...|.|.|   |    |   .. .|||..| ||  .| | | .         . ||.| |.
........vvekgrvngglavsrafGdhflkknkklkepyitaepdvkvvtl.tsedeflilaSDGlwdvlsnqevvdivrkllakgktndpqeaaelld

QDAQDYcmdETCIDDATAVV
. |...   ... |. |.||
eeairr...ggseDniTvvv
0049733 PP2C-like 128-440 1.4e-23 76.7 In-house 11-233 (235) alignment 
Range on Protein: 128-440
Range on HMM: 11-233/235.0
GSRHGKLNQDVPFCasfkqnghRIAIAAVFDGHGllGEIAAAMARDTMTALQPTFAWDSLLTQPEQGMREIFAQLDAAIVAAhdappaqytyigqsgsld
  |. | |.|  ..         ....||.||||  |  |...|....  .   .  . ||...|. .|..| ....|...                   
igrvrkvneDavlv........glllfavaDGhg..ghaagevasellvetllelllelllldleealrkaflaaneallel..................

frleahaipeldppsgyvctsrDGVPPRPIDFGCTAVVAVVVdETHVVVGNAGDAAAFVLlRDQAghedrdgysVEALSVQHTARSKAEQARVHETHPGA
                          |     |.|||||... . ...| |.||  |..| ||.          .. |.. |.     |..|... ..  
......................alaspelagmgtTavvalld.ggklyvanvGDsrayll.rdgk.........lvqltedhspvnelerqriitaggav

ahftgdgylapldptLAQYELQLTRSLGHRLLKragviadPEVRSQTWPVGEvhGVVACSDGITDELSGLDVLDRVLNaGTALEASEVLCQDAQDycmdE
                  . |.|||.||..|||       |.|.. ..  |.   .. .|||..| ||  ...| . .  .. || | |.. | .     
...............rvpgrlaltralGdlllk.......pdvtvlelepgd..flllasDGlwdvlsdeeivdllrs.ldleeaaerlvelala....r

TCIDDATAVVALF
   |. |.||. .
ggrDNiTvvvvrl
PP2C Protein phosphatase 2C 256-423 3e-19 62.6 Pfam-A 97-249 (255) alignment 
Range on Protein: 256-423
Range on HMM: 97-249/255.0
PIDFGCTAVVAVVVDEThVVVGNAGDAAAFVLLRDQAGhedrdgysvEALSVQHTARSKAEQARVHETHPGAAHftgDGYLAPLdptlaqyeLQLTRSLG
|.. |.|||||...... . | |.||. | .  .|.|           .|...|.. .. | .|. | .    .    |..           |...|.||
psksGstavvalirgkk.lyvAnvGDSravLcrkdnak.........keltedHkpsdedEreRIeeaggsvsn...ngrvngs........LavsRalG

HRLLKR---AGVIADPEVRSQTWPVGeVHGVVACSDGITDELSGLDVLDRVLNAGTA----LEASEVLCQDAQDY
   ||.   . |.|.|.|.| .      . .. .|||..| ||  .. | | .  ..     ||.| |...|...
dfelkpkeeqlvsaePdvtsvkltee.defliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaiar
PP2C Protein phosphatase 2C 256-423 3e-19 62.6 In-house 97-249 (255) alignment 
Range on Protein: 256-423
Range on HMM: 97-249/255.0
PIDFGCTAVVAVVVDEThVVVGNAGDAAAFVLLRDQAGhedrdgysvEALSVQHTARSKAEQARVHETHPGAAHftgDGYLAPLdptlaqyeLQLTRSLG
|.. |.|||||...... . | |.||. | .  .|.|           .|...|.. .. | .|. | .    .    |..           |...|.||
psksGstavvalirgkk.lyvAnvGDSravLcrkdnak.........keltedHkpsdedEreRIeeaggsvsn...ngrvngs........LavsRalG

HRLLKR---AGVIADPEVRSQTWPVGeVHGVVACSDGITDELSGLDVLDRVLNAGTA----LEASEVLCQDAQDY
   ||.   . |.|.|.|.| .      . .. .|||..| ||  .. | | .  ..     ||.| |...|...
dfelkpkeeqlvsaePdvtsvkltee.defliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaiar
PPM_PTC7 256-423 1.4e-18 60.2 In-house 98-253 (259) alignment 
Range on Protein: 256-423
Range on HMM: 98-253/259.0
PIDFGCTAVVAVVVDEThVVVGNAGDAAAFVLLRDQAGhedrdgysvEALSVQHTARSKAEQARVHETHPGAAHFtGDGYLAPLdptlaqyeLQLTRSLG
|.. |.|||||...... . | |.||. | .  ...|           .|...|.. .. | .|. . .    .  |.|..           |...|..|
pstsGstAvvalitgsk.lyvAnvGDSravLcrsgnav.........kqltedHkpsnedEreRiegaggsvsnv.gngrvngv........lavsRafG

HRLLKR-----AGVIADPEVRsQTWPVGEVHGVVACSDGITDELSGLDVLDRVLNAGT---ALEASEVLCQDAQDY
   ||.       |.|.|..  .|    | . .. .|||..| .|  .. | | .      . ||.| |...|...
dfelkpketeeqlvsaePdis.stkideedefliLasdGlwdvvsdqeavdlvrselskkdpmeaaeklvdeaiar
subfamily_PPM1A_pd Subfamily PPM1A 151-441 2.2e-15 49.8 In-house 42-281 (282) alignment 
Range on Protein: 151-441
Range on HMM: 42-281/282.0
IAIAAVFDGHGllG-EIAAAMARDTMTALQPTFAWDSlLTQPEQGMREIFAQLDAAIVAAHDAPPAQYTYIG---QSgsldfrleahaipeldppsgyvc
 .  ||||||.  | |.|  ...  ....  . .. .  .. ..  .|.  .|  ...|...|  .. |      .|                       
wsfFavfDGHa..Gsevakyvkkhllenileeeelke.aaleasekdevkealrqgfLaldeairelstdlktadks.......................

tsrdgvpprpidfGCTAVVAvVVDETHVVVGNAGDAAAfVLLRDQaghedrdgySVEALSVQHTARSKAEQARVHETHPGAAHFTGDGYlapldptlaqy
             |.|||.. .| |.|... |.||. | || |..         ... |.  | . .. |. |...          .|            
.............GsTavtv.lvsekhliianlGDsRa.vlcrng.........kaaflteDHkpsrpkEkkRieqAGGsvvvsRvnGa...........

eLQLTRSLGHRLLKR--------AGVIADPEVRSQTWPVGEVHGVVACsDGITDELSGLDVLDRVLNAGTALEASEVLCQDAQDYCMDETCIDDATAVVA
 | ..|.||   .|.          |.|.|||.|.     . . |.|| ||| | ||  .|.. | .  .. .  | ....  |... .   |  ...| 
.LAvsRalGDyeykeeeekkaeeqlvsaepevtsierseeddflvlac.DGiwDvlsdeevvelvrkrlevadeleevakalvdkalekgsrDNlsvlvv

LFP
||.
lfa
subfamily_PPM1K_pd Subfamily PPM1K 259-439 6.1e-15 48.1 In-house 98-257 (263) alignment 
Range on Protein: 259-439
Range on HMM: 98-257/263.0
FGCTAVVAVVVDETHVVVGNAGDAAAfVLLRDqaghedrdGYsVEALSVQHTARSKAEQARVHETHpGAAHFTGdgylapLDPTLAQYELQLTRSLGHRL
 | || |... | |..|. . ||. | .| |.        |   . |.  |.   . |. |....  |  ...       |.  |    | .|||||   
sGttatvsllrdGtelvlaslGdsra.ilcrn........Gk.akkltrdhdPeleeekerikaag.Gsvewns......lgkplvngrlamtrslGdld

LKRAGVIADPEVRSQTWPVGEVHGVVACSDGITDELSGLDVLDRVLNAGTALEASEVLCQDAQDYCMDetciDDATAVVAL
||| ||||.|| .|     ..   .| ..|||.. ..  .. | |       ||...|.. | .|  .    |.|||||  
lkryGviatPetkslkvdhaadsflvlitdgisfvvnsqelcdlvrlchdpeeaahalteqalqygse....dnatavvvp
PPM_PTC7_SpoIIE 146-420 5.3e-14 45.6 In-house 29-221 (230) alignment 
Range on Protein: 146-420
Range on HMM: 29-221/230.0
QNGHRIAIAAVFDGHGLLGEIAAAMARDTMTALQpTFAWDslltQPEQGMREIFAQLDAAIVAAhdappaqytyigqsgsldfrleahaipeldppsgyv
  |.  .. ...||||.    |....|... .|  .  ..    .||. .|.....|.|..  .                                    
sggrlalvvgdvdGhGgraalamgllrtalrela.fagle....kpeeilrrlnlalaadlede....................................

ctsrdgvpprPIDFGCTAVVAVVVDET-HVVVGNAGDAAAFVLLRdQAGhedrdgysvealsvqhtarskaeqarvhethpgAAHFTgDGYLAP-L--DP
          |.. |.|||||..  .| .. | ||||  ....   ..|                                  .. . ..  .| |  .|
..........psssgaTavvalidpstgklyvanaGdsppllvrd.dgg.................................ereri.vagglpslGilp

TLAQYELQLTRSLGHRLLKR--AGVIADPEvRSQTWPVGEVHGVVACSDGITDELSGLDVLDRVLNAGTALeASEVLCQDA
.    .|..... | .||.     | | |.  |...  |. . ....|||..| ||  ...| |..   .. |.| | .|.
grvfgvlavslapGdllllytDGvveaepd.tsdgelfgkdeflilasdglwdvlspqelvdlvrdelekp.aaeglleDD
subfamily_ILKAP_pd Subfamily ILKAP 260-405 1.6e-10 33.6 In-house 114-241 (293) alignment 
Range on Protein: 260-405
Range on HMM: 114-241/293.0
GCTAVVAVVVDEThVVVGNAGDAAAFVLLRDQAGHEdrdgYSVEALSVQHTARSKAEQARVHEthpgAAHFTGDGYLAPLdptlaqyeLQLTRSLGHRLL
|.||.| .|.|.. . |.| ||. |... ....|..    ... .|...||. .. |. |..     |  .  || .  .        |. .||.|    
Gstatvvlvldnv.lyvanlGdskavlvrkkeegdk....iasvvLtkdhtpvkyeerkriqk....aGgvvrdgrvlGv........levsrsiGdgrf

KRAGVIADPEVRSQTWPVGEVHGVVACsDGITDELSGLDVLDRVLN
||.|||. |.|.  .    . . |.|| ||. . .|  .|.. .|.
krlGvistPdvkkceLtendlfvvlaC.dGLwkvfsadevvkfilk
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 253-437 1.5e-09 30.6 In-house 89-250 (255) alignment 
Range on Protein: 253-437
Range on HMM: 89-250/255.0
PPRPIDFGCTAVVAVVVDEtHVVVGNAGDAAAFVLlrdqagheDRDGYSvEALSVQHTARSKAEQARVHEThpGAAHFTGdgylapLDPTLAQYELQLTR
 .||.  |.||........ .|.. | ||. . .         ..|| . . ||. |    . |. |..|   |    ..         .     | ..|
serpkfiGttaasvliied.kvyianvGdsrvvlc........qkdgta.krlsldhkPseeseekrisel..GGtvvst......vvtsrvnGtlavsr

SLGHRLLKrAGVIADPEVR-SQTWPVGEVHGVVACsDGITDELSGLDVLDRVLNAGTALEASEVLcqdaQDYCMDETCIDDATAVV
.||   |.   |..||..  | .    . . ..|| ||| |..|  .  . |..   . .|.| |    .|.       |. . .|
alGdsfle.PfvvpdPdlsqsleiskkdkflilac.dGiwdlisdeeaveivagisdpekaaekl....rdlayssGstdnisviv
PP2C_2 Protein phosphatase 2C 130-406 3.4e-09 29.3 Pfam-A 7-193 (212) alignment 
Range on Protein: 130-406
Range on HMM: 7-193/212.0
RHGKLNQDVPFcasFKQNGHRIAIaAVFDGHGL--LGEIAAAMARDTMtalqpTFAWDSLLTQPEQG-MREIFAQLDAAIVAAHDappaqytyigqsgsl
| || .||  .   .... ..  . || ||.|   .....|..|  ..     . |  .||.. ..   .... |. ..| |. .               
rkgkpcqDala...ireasdgwll.aVADGaGsakrSdkGarlaveaa.....gealeklleeeseqeeeallrqieneilasvk...............

dfrleahaipeldppsgyVCTSR--DGVppRPIDFGCTAVVAVvVDETHVVVGNAGDAAAFVLLRDQA----GHEDRDGYSVEalsvQHTARSKAEQARV
                     ..  ..    . |...| ..|| ......|... || |..| .||.     |..|  .|. |     . ..|.... ..
..................lkqeaeaqqe..elkdyatTlllav.itpgeivffqiGDgaivvrdrdgevqllgepdsgeyane....ttfltsedaeeel

hethpgaahftgdgylapldptlaqyelqltrslghrllkragviadpevRSQTWPVGEVHGVVACSDGITDELSGLDVLDRVLNA
                                                  | ..... .. ... ..||. |.|.  . . ..|. 
..................................................rirrlklepgdalllmTDGvsdslrkeepfrellae
PP2C_2 Protein phosphatase 2C 130-406 3.4e-09 29.3 In-house 7-193 (212) alignment 
Range on Protein: 130-406
Range on HMM: 7-193/212.0
RHGKLNQDVPFcasFKQNGHRIAIaAVFDGHGL--LGEIAAAMARDTMtalqpTFAWDSLLTQPEQG-MREIFAQLDAAIVAAHDappaqytyigqsgsl
| || .||  .   .... ..  . || ||.|   .....|..|  ..     . |  .||.. ..   .... |. ..| |. .               
rkgkpcqDala...ireasdgwll.aVADGaGsakrSdkGarlaveaa.....gealeklleeeseqeeeallrqieneilasvk...............

dfrleahaipeldppsgyVCTSR--DGVppRPIDFGCTAVVAVvVDETHVVVGNAGDAAAFVLLRDQA----GHEDRDGYSVEalsvQHTARSKAEQARV
                     ..  ..    . |...| ..|| ......|... || |..| .||.     |..|  .|. |     . ..|.... ..
..................lkqeaeaqqe..elkdyatTlllav.itpgeivffqiGDgaivvrdrdgevqllgepdsgeyane....ttfltsedaeeel

hethpgaahftgdgylapldptlaqyelqltrslghrllkragviadpevRSQTWPVGEVHGVVACSDGITDELSGLDVLDRVLNA
                                                  | ..... .. ... ..||. |.|.  . . ..|. 
..................................................rirrlklepgdalllmTDGvsdslrkeepfrellae
subfamily_PDP_pd Subfamily PDP 260-329 6.9e-09 28.3 In-house 153-216 (398) alignment 
Range on Protein: 260-329
Range on HMM: 153-216/398.0
GCTAVVAVvVDETHVVVGNAGDAAAFVLLRDQAGHedrdgYSVEALSVQHTARSKAEQARVHETHPGAAH
| .|..|. ...|.. | |.||..| .  ... |.     ... .|| ..||....|  |... |||  .
Gacallal.iegtelhvAntGDcravlgvqeeegs.....weavkLskdqtadneeEveRikkeHPgees
subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 260-371 4e-08 26.1 In-house 86-197 (292) alignment 
Range on Protein: 260-371
Range on HMM: 86-197/292.0
GCTAVVAVVVDETHVVVGNAGDAAAfVLLRDQAGHEdrdgYSVEALSVQHTARSKAEQARVHETHPGAA--HFTGDGYLAPLDP---TLAQYELQLTRSL
. ..| |.| |.  ... | ||. | .| |  .| .    | .  || .|      |.||.  .       .  | |.  .         . .| |.|.|
ttavvcarvrddralilanvGdsra.llgrclggsd....yeliPlsrdhkPedPderarilraGGrveptrvrgwgfrGtarvwrrrqqeGdlalsral

GHRLLKRAGVIADPEVR
|   |. |||.|.||..
GdfhlfeaGvvaePelq
PP2C_SIG_SM00331 143-437 1.9e-07 23.8 In-house 23-214 (217) alignment 
Range on Protein: 143-437
Range on HMM: 23-214/217.0
SFKQNGHRIAIaAVFDGHGlLGEIAAAMARDTMTALQPTFAWDsllTQPEQGMREIFAQLDAAivaahdappaqytyigqsgsldfrleahaipeldpps
 .| |..|... .|.||.|  |  |||... . |||.  .  .   . ..| ....   ...                                      
vvklnegrlll.vvaDgmG.kGlaAaaassqlrtalrellseg...eelsqalkrlnraiyee.....................................

gyvctsrdgvpPRPIDFGCTAVVAVV-VDETHVVVGNAGDAAAFVLLrD-QAGHE--Drdgysvealsvqhtarskaeqarvhethpgaahftgdgylap
               . ..|...|..   . .. . ||||   ..|  | .  ..  |                                          
...........keekgmfaTlllalydfssgklsyanaGdsrpyllr.dgklveilkd..........................................

ldptlaqyelqltrslghRLLKRAGVIADPEVRSQTWPVGEVHGVVACSDGITDELS----GLDVLDRVLNAGTALEASEVLCQDAQDYCM---DETCID
                   . . .|.. ...|....  . .   .. ..||.|.  |    . . | ..| . .  || |.  .. .. .    ..   |
..................vegaplGlepevsvdirelelekgdllllytDGltearsekgfaeerleeiledlvdseaqelaqkiveellelakgsngeD

DATAVV
|.| ||
diTvvv
subfamily_PPM1G2_pd Subfamily PPM1G2 259-429 1.9e-07 23.3 In-house 115-269 (287) alignment 
Range on Protein: 259-429
Range on HMM: 115-269/287.0
FGCTAVVAVVVDEThVVVGNAGDAAAFVLlrdqaghedRDGYsVEALSVQHTARSKAEQARVHETHpGAAHFT-GDGYLApLDPTLAQYELQLTRSlghR
 |.||||... .|  ..|.||||. | .           .|  |.|||. |  ....|. |. ..  |  ..    | || |   |. .| . . .    
aGstavvvlikeek.lyvanaGDsravls.........skgn.vkalsfDhkPqeesekkriiaag.GfvelnrvngnLa.lsralgDfefkknvk...k

LLKRAGVIADPEVRSQTWPvGEVHGVV-ACsDGITDELSGLDVLDRVLNAGTALEASEVLCQDAQDYCMDETC
  . . | | |.|  .     .   .| || ||| | |.  .|.| | .  .   . . ....  | |. ...
kpeeqivtavPDvlvkkld.eddeflvLaC.DGiWDvltnkevvdlvrerlvsgakldeiieelldkclapds
subfamily_TAB1_pd Subfamily TAB1 257-397 6.9e-07 21.4 In-house 127-263 (333) alignment 
Range on Protein: 257-397
Range on HMM: 127-263/333.0
IDFGCTAVVAVVVDEtHVVVGNAGDAAAFVLLRDQaghedrdGYSVEALSVQHTARSKAEQARVHETHPGAAHFTGDGYLAPLDPTLAQYELQLTRSLG-
|  | |||||... . .. | |.||. | .. | .          |. |||.||   . |  |...    . .    . |.  ..| .  .....     
isgGttAvvalifnn.kLyVaNvGdsrAllvkrke.......sekvkqLsvdHttdNedEllRlkdLGldieqikrnkrlgskentRsiGdykvkkgykd

HRLLKRA---GVIADPEVRsQTWPVGEVHG-VVACSDGITDELSGL
  .|..|    |||.|..   ..|. .. . .|  |||.   |  .
vdilssakgePviaePdiq.gaypiddityflvlmSdGvyktLeev
subfamily_PPM1G_pd Subfamily PPM1G 258-434 8e-07 21.4 In-house 295-458 (473) alignment 
Range on Protein: 258-434
Range on HMM: 295-458/473.0
DFGCTAVVAVVvDETHVVVGNAGDAAAfVLLRDqaghedrdGYSVEaLSVQHTARSKAEQARVHEThPGaaHFTGDGYLA---PLDPTLAQYELQLTRSL
| |.|||||..  | ...| ||||. . || |.        |  .. ||. |    . |..|...   |  . . || .     |   |  .  . ...|
dsGttAvvaLl.kekklivAnaGDsRc.vlsrn........GkAld.lslDHkPeDevEleRiekA.GG..kvdedgRvnGGLnlsRAlGDhaYkkneeL

GHRLLKragVIADPEVRSQTWPVGEVHGVVACsDGITDELSGLDVLDRVLNAGTALEA--SEVLCQDAQDYCMDETCIDDAT
...      . | |... .|    .   |.|| ||| . ..  .|.| | .  .  |    . ....  | |. .   .| |
plkeqm...isAlPDikvltlteedeFlvlAc.DGiWnvmesqevvdfvraklkkgeesvlseiveeLlDaclapdtsgDGt