Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Choan-PPM1K-like_pd | Subfamily Choan-PPM1K-like | 445-736 | 4.1e-181 | 594.0 | In-house | 1-292 (292) | alignment | ||
Range on Protein: 445-736
Range on HMM: 1-292/292.0
AGNPKENQDGFLVYEGSSALPFLAAVMDGHGVNGRKVSGFAESTLGVEILESYRQNQALSEALVNGIVSTAAKLRKSTIDARESGTTAVVCARTPDGRQL
|.|.|||||.||..|||.||.|||||.|||||||.||...||.||.||.||..||.|.|||||...|...||||.|.|||||||.||||||||..|.|.|
aankkenqdrfllvegsealtflaavldGhGvnGdkvaqlaedtlevelleltrqlqelsealllrildiaakldkltidaresattavvcarvrddral
IVANVGDSRCVLGRCLGGSRYQPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVRGWGFQGPARVWRRRQQEGGLALSRSVGDFHLFEAGVVAEPELQIHA
|.|||||||..||||||||.|..|||||||||.||.||.||.||||.|||||||||||.|.|||||||||||.|||||..||||||||||||||||||||
ilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraGGrveptrvrgwgfrGtarvwrrrqqeGdlalsralGdfhlfeaGvvaePelqiha
GRQYLGRGPGLWTRSSIARHIAYQHPLTSDVPLGLDRKLEKTLDSQDHFIVLGSDGVFDHLSNAQVILFLAKYQEGADFVITSNSLECHLSS
|||||||||||||||||||||||||||||||||||||||||.|||.|.|.||.||||.|.|.||.|.|.|||.||.||.|||...||..||.
grqylgrgpglwtrssiarhiayqhpltsdvplgldrklekeldsddaflvlasdGvldvllnaevvlllaksqeaadkvitelaleyglsd
|
|||||||||
0034914 | PP2C-like | 444-717 | 5.1e-39 | 127.0 | In-house | 28-256 (295) | alignment | ||
Range on Protein: 444-717
Range on HMM: 28-256/295.0
YAGNPKENQDGFLVYEGS---SALPFLAAVMDGHGvnGRKVSGFAESTLGVEILE--------SYRQNQALSEALVNGIVSTAAKLRKSTID---ARESG
|. |.|.| .||. . .|..| |||| | ... .| ..| ..|| .. . |||....... .|.. ... . ||
dqGrrksneDavlvvlnllslledlllfgvfDGhg..GhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallrpelagsG
TTAVVCARtpDGRQLIVANVGDSRCVLGRclGGsryQPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVRgwgfqgparvwrrrqqeGGLALSRSVGDFHL
|||||. |..|.||||||||.|| | .| ....|..||||... ||.||..|||.| || |.||..|..|||.|
tTavvali..rgnklyvanvGDSravllr..ng...elvqltvdhkpvnelererilsaggavshgrvn.................gvlavtRalGdfdl
F--------EAGVVAEPELQIHAGRQ--YlgrgpglwtrssiarhiayqhpltsdvplgldrklektldsqdHFIVLGSDGVFDHLSNAQVILFLAKY
. | .|.|||..... . .|..|.|||..|.||| ... .....
klllslllleplvsaePdvtvleltledd...........................................dfllLasDGlwdvlsneeivdivrsl
|
|||||||||
PP2Cc_SM00332 | 446-735 | 2e-38 | 125.4 | In-house | 19-244 (274) | alignment | |||
Range on Protein: 446-735
Range on HMM: 19-244/274.0
GNPKENQDGFLVYEG--SSALPFLAAVMDGHGvnGRKVSGFAESTLGVEILESYRQNQA-----LSEALVNGIVSTAAKLRKSTIDAR----ESGTTAVV
|..|...| . |. ... . .| |||| | .|. |. . | . |. . . ||| ....|| ..... . ||.||||
gwrksmeDahvvvvdlveeedwlffgvfDGhg..GsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelenalsGstavv
CARTPDGrqLIVANVGDSRCVLGRCLGgsryqPIPLSRDHKPSDPGERQRIQRAGGyveptrvrgwgfqgparVWRRRQQEGGLALSRSVGDFHLF----
. . . |.||||||||.||.| ..||.||||.|. ||.||..||| | .... ||||.||. ||..|
allkked..lyvanvGDSravlcrngk.....avqlsvdhkpedederkRikkagg.................vvekgrvngglavsrafGdhflkknkk
--EAGVVAEPELQIHAGrqylgrgpglwtrssiarhiayqhpltsdvplgldrklektlDSQDHFIVLGSDGVFDHLSNAQVILFLAKYQEGAdfvitsn
| ...|||. .... .|.| |..| |||..|.||| .|. .. | .
lkepyitaepdvkvvtl..........................................tsedeflilaSDGlwdvlsnqevvdivrkllakg.......
slechlS
.
......k
|
|||||||||
PP2C | Protein phosphatase 2C | 466-643 | 2.1e-32 | 105.7 | Pfam-A | 35-196 (255) | alignment | ||
Range on Protein: 466-643
Range on HMM: 35-196/255.0
FLAAVMDGHGvnGRKVSGFAESTLGvEILESYRQNQAL---SEALVNGIVS-TAAKLRK---STiDARESGTTAVVCARTPDGrqLIVANVGDSRCVLGR
. ||.|||| ||... .|...| |||.. .. . | ..|| ... . |. .|.. .| ||.||||. ... |.||||||||.||.|
affavfdghg..greaakyarehle.eilkeqksflelekvekalrksfladtdeelksskant.epsksGstavvalirgkk..lyvAnvGDSravLcr
CLGGSryqpIPLSRDHKPSDPGERQRIQRAGGYVE-PTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFE---AGVVAEPELQIH
. |..||||||. ||.||..|||.|. .||.| ||.||..|||.|.. . |.|||... .
kdnak....keltedHkpsdedEreRIeeaggsvsnngrvngs.................LavsRalGdfelkpkeeqlvsaePdvtsv
|
|||||||||
PP2C | Protein phosphatase 2C | 466-643 | 2.1e-32 | 105.7 | In-house | 35-196 (255) | alignment | ||
Range on Protein: 466-643
Range on HMM: 35-196/255.0
FLAAVMDGHGvnGRKVSGFAESTLGvEILESYRQNQAL---SEALVNGIVS-TAAKLRK---STiDARESGTTAVVCARTPDGrqLIVANVGDSRCVLGR
. ||.|||| ||... .|...| |||.. .. . | ..|| ... . |. .|.. .| ||.||||. ... |.||||||||.||.|
affavfdghg..greaakyarehle.eilkeqksflelekvekalrksfladtdeelksskant.epsksGstavvalirgkk..lyvAnvGDSravLcr
CLGGSryqpIPLSRDHKPSDPGERQRIQRAGGYVE-PTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFE---AGVVAEPELQIH
. |..||||||. ||.||..|||.|. .||.| ||.||..|||.|.. . |.|||... .
kdnak....keltedHkpsdedEreRIeeaggsvsnngrvngs.................LavsRalGdfelkpkeeqlvsaePdvtsv
|
|||||||||
PPM_PTC7 | 466-643 | 5.2e-32 | 104.3 | In-house | 35-201 (259) | alignment | |||
Range on Protein: 466-643
Range on HMM: 35-201/259.0
FLAAVMDGHGvnGRKVSGFAESTLGVEILESYRQNQA--LSEALVNGIVS--TAAKLRK---STiDARESGTTAVVCARTPDGrqLIVANVGDSRCVLGR
. || |||| ||... .|...| . |... .. |..|| ... . |. .|.. .| ||.||||.. |.. |.||||||||.||.|
affavfdghg..greaakyarehleeilkerksfeeleklekalrksflaldtdeelksseant.epstsGstAvvalitgsk..lyvAnvGDSravLcr
CLGGSryqpIPLSRDHKPSDPGERQRIQRAGGYVE---PTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFE-----AGVVAEPELQIH
. .|..|||||.. ||.||..|||.|. .||.| ||.||..|||.|.. |.|||. . .
sgnav....kqltedHkpsnedEreRiegaggsvsnvgngrvngv.................lavsRafGdfelkpketeeqlvsaePdisst
|
|||||||||
subfamily_PPM1G2_pd | Subfamily PPM1G2 | 467-715 | 1.8e-29 | 95.6 | In-house | 54-244 (287) | alignment | ||
Range on Protein: 467-715
Range on HMM: 54-244/287.0
LAAVMDGHGvnGRKVSGFAESTLGVEILE--SYRqNQALSEALVNGIVSTAAKLRKS-TIDARESGTTAVVCARTPDGrqLIVANVGDSRCVLgrCLGGS
| ||.|||| |.||. .| . | | . |.. ..||...| .....| .|.| ... ..|.|||| . . |.|||.||||.|| . |.
lfavfDGhG..Gakvakyagkklikkiakkksfk.egaleqilkdafletDeellkdeklkdesaGstavvvlikeek..lyvanaGDsravl..sskgn
ryqPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVrgwgfqgparvwrrrqqEGGLALSRSVGDFHlFEAGVVaepelqihagrqylgrgpglwtrssiar
||.||||.. .|..||. |||.|| || | |||||..|||. | .|
...vkalsfDhkPqeesekkriiaagGfvelnrv.................ngnLalsralgDfe.fkknvk............................
hiayQHPLTSDVPLGLDRKLEKtLDSQDHFIVLGSDGVFDHLSNAQVILFLA
..| | | ..| ||..| |.|| ||..| |.|..|. ..
....kkpeeqivtavPDvlvkk.ldeddeflvLaCDGiWDvltnkevvdlvr
|
|||||||||
0049733 | PP2C-like | 446-716 | 1.3e-28 | 93.0 | In-house | 12-203 (235) | alignment | ||
Range on Protein: 446-716
Range on HMM: 12-203/235.0
GN-PKENQDGFLVyegssaLPFLAAVMDGHGvnGRKVSGFAESTLGVEILESYRQNQA--LSEALVNGIVSTAAKLRKSTID---ARESGTTAVVCARTp
|. |.|.| .|| .|.|| |||| | ....| ..| .|| ... | |||.. . . . |.. ... . .||||||. .
grvrkvneDavlv......glllfavaDGhg..ghaagevasellvetllelllelllldleealrkaflaaneallelalaspelagmgtTavvalld.
dGRQLIVANVGDSRCVLGRclggsRYQPIPLSRDHKPSDPGERQRIQRAGGYVeptrvrgwgfqgparvwrrrQQEGGLALSRSVGDFHLFeagvvaepe
|..|.||||||||..| | . . ..|..||.|... |||||..|||.| |.|||.|..||..|
.ggklyvanvGDsrayllr.....dgklvqltedhspvnelerqriitaggav....................rvpgrlaltralGdlllk.........
lqihagrqylgrgpglwtrssiarhiayqhpltsdvplglDRKLEKTLDSQDhFIVLGSDGVFDHLSNAQVILFLAK
. .|...| |..| |||..|.||. ... .|..
........................................pdvtvlelepgd.flllasDGlwdvlsdeeivdllrs
|
|||||||||
subfamily_PPM1A_pd | Subfamily PPM1A | 466-637 | 2.8e-26 | 85.5 | In-house | 43-200 (282) | alignment | ||
Range on Protein: 466-637
Range on HMM: 43-200/282.0
FLAAVMDGHGvnGRKVSGFAESTLGVEILES--Y-------RQNQALSEALVNGIVSTAAKLRKSTIDAR---ESGTTAVVCARTpdGRQLIVANVGDSR
. ||.|||. |..|. .....| .|||. . .......||| .|.... ..|... |.. .||.|||.. . ..||.||.||||
sfFavfDGHa..GsevakyvkkhllenileeeelkeaaleasekdevkealrqgfLaldeairelstdlktadksGsTavtvlvs..ekhliianlGDsR
CVLGRclGGsryQPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFEAGVVAE
|| | .| . . |..|||||.| |..||. ||| | || | ||.||..||... |. .
avlcr..ng...kaaflteDHkpsrpkEkkRieqAGGsvvvsRvnGa.................LAvsRalGDyeykeeeekka
|
|||||||||
subfamily_PPM1K_pd | Subfamily PPM1K | 445-641 | 4.8e-22 | 71.3 | In-house | 12-193 (263) | alignment | ||
Range on Protein: 445-641
Range on HMM: 12-193/263.0
AGNPKENQDGFLVYEGSSALPFLaAVMDGHGvnGRKVSGFAESTLGVEILESYRQNQALSEALVNGIVSTAAKLRK------STIDARESGTTAVVCArT
| .||.| . . | . | .. || |||. | |. . | . . . ... | . |.| ||.. . . .||||| |.
iGkraenedriklkeldpellyv.avfdGha..GsaaadfvhdklekilkrllekekdleivlknafeeldkklkrylefsvaeaellssGttatvsl.l
PDGRQLIVANVGDSRCVLGRclGGsryQPIPLSRDHKPSDPGERQRIQRAGGYVEptrvrgWGFQGPARVwrrrqqEGGLALSRSVGDFHLFEAGVVAEP
|| .|..|..|||| .| | | .. |.|||.|. |..||..||| || | | .| .| ||..||.||. | . ||.|.|
rdGtelvlaslGdsrailcr..nG...kakkltrdhdPeleeekerikaagGsve......wnslgkplv......ngrlamtrslGdldlkryGviatP
ELQ
| .
etk
|
|||||||||
subfamily_PPM1G_pd | Subfamily PPM1G | 522-628 | 3.5e-21 | 68.7 | In-house | 290-373 (473) | alignment | ||
Range on Protein: 522-628
Range on HMM: 290-373/473.0
TIDARESGTTAVVCARtpDGRQLIVANVGDSRCVLGRClggsrYQPIPLSRDHKPSDPGERQRIQRAGGYVEPTrvrgwgfqGpaRVwrrrqqEGGLALS
..|||||||. ...|||||.||||||| | . . || |||| |. |..||..||| |. | || .||| ||
eepGedsGttAvvaLl..kekklivAnaGDsRcvlsrn.....GkAldlslDHkPeDevEleRiekAGGkvded........g..Rv......nGGLnls
RSVGDFH
| .||.
RAlGDha
|
|||||||||
subfamily_PPM1L_pd | Subfamily PPM1L | 466-639 | 7.8e-21 | 67.5 | In-house | 36-198 (269) | alignment | ||
Range on Protein: 466-639
Range on HMM: 36-198/269.0
FLAAVMDGHGvnGRKVSGFAESTLGVEILESY------RQNQA---LSEALVNGIVSTAAKLR-KSTIDARESGTTAVVCARTpdGRQLIVANVGDSRCV
. ||.|||| | . ||.. | .|.. ..|. |. |.. |.| || | . ..||||.. . ...|||||||||| |
sffavfdGhG..GefaaefakdvlvkaiknklieldadkentepinfsklltdeilsvdekllekakraediaGttalialvq..esdlivanvGdsrGv
LGRCLGgsryQPIPLSRDHKPSDPGERQRIQRAGGYVeptrvrgwGFQGparVWRRrqqEGGLALSRSVGDFHLFEAGV-VAEPE
| | . |||| |||| .. ||.||..|||.. |.| ||| .| || ||..||. | . . .|.|.
lydkrG....kaiplsfdhkpqqvkerkrikkaGGfi........afrG...vwrv...aGvlatsralGdyplkdknlviadpd
|
|||||||||
subfamily_PPM1E_pd | Subfamily PPM1E | 469-640 | 6.9e-19 | 61.0 | In-house | 44-192 (265) | alignment | ||
Range on Protein: 469-640
Range on HMM: 44-192/265.0
AVMDGHGvnGRKVSGFAESTLGVEILESYRQNQALSEALVNGIVSTAAKL-RKSTIDARESGTTAVVCARTpdGRQLIVANVGDSRCVLGRclggsRYQP
||.|||| | . . .| . | . . .... ||| ... | .. .|.. .. .||.||||.. . ..|| || .|||. .| | .
avfDGHg..GveaakyaaahlhellvrqeklkedpaealkeafkltDerflqkaereklksGstavvvlie..kdqlyvaWlGDsqallvr.....kgea
IPLSRDHKPSDPGERQRIQRAGGYVeptrVrgWgFqGparVWRRrqqEGGLALSRSVGDFHLfEAGVVAEPEL
. | . |||... |..||. ||| | | . . | .|| | |..||..|| .| .. |..|...
vqlmkpHkPeredEkkRieeagGlv....v..v.i.g...awRv...nGvLsvsRaiGDvkl.kpyvsgeadv
|
|||||||||
PPM_PTC7_SpoIIE | 463-713 | 1e-17 | 57.7 | In-house | 32-204 (230) | alignment | |||
Range on Protein: 463-713
Range on HMM: 32-204/230.0
ALPFLAAVMDGHGVNGRKVSGFAESTLGVEILESYRqnqALSEALVNGIVSTAAKLRKStidARESGTTAVVCARTPDGRQLIVANVGDSRCVLGRClGG
| .. .. ||||. ...| . ..| .. .. . ..|.| .. ||.|... .||.||||. .|. ..| |||.|||...| | .|
rlalvvgdvdGhGgraalamgllrtalrelafagle...kpeeilrrlnlalaadlede...psssgaTavvalidpstgklyvanaGdsppllvrd.dg
SryqpiplsrdhkpsdpgERQRIqRAGGYVE----PTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFEagvvaepelqihagrqylgrgpglwtr
|| || ||| .. |.|| | ||.|.. ||. |.
g.................ereri.vagglpslGilpgrvfgv.................lavslapGdlllly...........................
ssiarhiayqhpltSD-VPLGLDRKLEKTLDSQDHFIVLGSDGVFDHLSNAQVILF
.| | .. .. |.. |.|..|.|||..|.||..... .
..............tDGvveaepdtsdgelfgkdeflilasdglwdvlspqelvdl
|
|||||||||
subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 468-641 | 1.4e-17 | 56.9 | In-house | 39-188 (255) | alignment | ||
Range on Protein: 468-641
Range on HMM: 39-188/255.0
AAVMDGHGvnGRKVSGFAESTLGVEILESYRQNQA-LSEALVNGIVSTAAKLRKSTidaRESGTTAVVCARTPDgrQLIVANVGDSRCVLGRCLGGSRYq
|..|||| ||. . || .| . | |.| ..| . .. .. . . . ||||.. . | . ..||||||| ||.. | ..
yalfdGhg..GraaakfaseelykilaelldlnnanPvkslkkaykeistqiserp...kfiGttaasvliied..kvyianvGdsrvvlcqkdgtakr.
pipLSRDHKPSDPGERQRIQRAGGYVEPTrvrgwgfqgparvWRRRQQEGGLALSRSVGDFHLfEAGVVAEPELQ
|| |||||.. |..||...|| | | . .| ||.||..|| .| | ||..|.|.
...lsldhkPseeseekriselGGtvvst.............vvtsrvnGtlavsralGdsfl.ePfvvpdPdls
|
|||||||||
subfamily_ILKAP_pd | Subfamily ILKAP | 469-640 | 1.6e-17 | 56.6 | In-house | 47-207 (293) | alignment | ||
Range on Protein: 469-640
Range on HMM: 47-207/293.0
AVMDGHGvnGRKVSGFAESTLGVEILESYRQN------QALSEALVNGIVSTAAKLRKSTIDA---RESGTTAVVCARTPDgrQLIVANVGDSRCVLGRC
|| |||. |.. | || ..| .||| . .. . . .||. | .. | | |.||.|. . | |||.|||..|| |.
avfdGha..GsrasefaaeklhkkileklpksdvsakekeikkclvdsfkktdeefLklaskakPvWkdGstatvvlvldn..vlyvanlGdskavlvrk
LGGSR-YQPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFEAGVVAEPEL
.. .. ..|..||.| . ||.|||.|||.|. || | | |||.|| . ..||.. |..
keegdkiasvvLtkdhtpvkyeerkriqkaGgvvrdgrvlGv.................levsrsiGdgrfkrlGvistPdv
|
|||||||||
Nup35_RRM | Nup53/35/40-type RNA recognition motif | 912-982 | 7.4e-17 | 47.5 | Pfam-A | 9-94 (101) | alignment | ||
Range on Protein: 912-982
Range on HMM: 9-94/101.0
CVTIFGFGLADLDLVMTEFERCGRILRR-------------ETKTNCNWLHVQFDDQLSAQRALSKHGMVLSARLMVGVQPC--LD
|..||| .. . |...|...|.|| .. |. ||...... ..||..||.. |..| |.|||... .
svivFGfpesianevlehFskfGeiledvqvlklgkglnpkpiptgenwvkltYksessaskAlqengtilngslivgvsyskaaa
|
|||||||||
subfamily_PPM1D_pd | Subfamily PPM1D | 468-631 | 2.6e-15 | 49.3 | In-house | 38-214 (309) | alignment | ||
Range on Protein: 468-631
Range on HMM: 38-214/309.0
AAVMDGHGvnGRKVSGFAESTLGVEILES----YRQNQALSEALVNGIVSTAAKLRKSTI--------DARESGTTAVVCARTpdGRQLIVANVGDSRCV
||.|||| |.. . || . | .| . ...... ||. .. ..| ...|. . .|||| | . ...| ||.||||. |
vavfDGHG..GkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkkleeWpktksgllstaGttasvviir..reklyvahvGDsaiv
LGRCLG-GSRYQPIPLSRDHKPSDPGERQRIQRAGGYVEPT----RVRgWGF-QGPARVWRRRQQEGGLALSRSVGDFHLFE
|| .. .. .| .||||..| |..||...|| | || | . . . ... ||..||.||. ..
lgvkepkekklrakeltkdHkPespeekerieelGGevaaksGvkRvv.WkRprlehngptvideiPFLavaRslGDlWsyn
|
|||||||||
subfamily_PDP_pd | Subfamily PDP | 515-588 | 6.8e-11 | 34.9 | In-house | 139-210 (398) | alignment | ||
Range on Protein: 515-588
Range on HMM: 139-210/398.0
AAKLRKSTIDARESGTTAVVCarTPDGRQLIVANVGDSRCVLGRCLGGSRYQPIPLSRDHKPSDPGERQRIQRA
| ...... ||..|.. .|..| |||.||.|.|||. . . .. ..||.|. . . | .||...
kekslreallvalsGacalla..liegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikke
|
|||||||||
subfamily_KAPP-like_pd | Subfamily KAPP-like | 468-596 | 3.1e-09 | 29.3 | In-house | 37-165 (266) | alignment | ||
Range on Protein: 468-596
Range on HMM: 37-165/266.0
AAVMDGHGVNGRKVSgfAESTLGVEILESYRQ---------NQALSEALVNGIVSTAAKLRKStidaRESGTTAVVCARTPDGRQLI--VANVGDSRCVL
||.||| .| .. |. . |. . .. . |. | | . . |||.. |.|| .. ||.| ||||||| |
favfdGhaGkGaada..akklfpkelekllkstkqddGGdniydqskllenafkevdaklkdf....eyeGatatlalvwsdGqqrylqvanvGdssafl
GRclGgsrYQPIPLSRDHKPSDPGERQRIQRAGGYVEPTR
| | . . || ||| || |.|||. | . ..
sr..G...neslelskdhkakdpeekqrikddGitlsdnq
|
|||||||||
Nup35_RRM_2 | Nup53/35/40-type RNA recognition motif | 913-962 | 7e-09 | 21.9 | Pfam-A | 4-53 (53) | alignment | ||
Range on Protein: 913-962
Range on HMM: 4-53/53.0
VTIFGFGLADLDLVMTEFERCGRILRRETKTNCNWLHVQFDDQLSAQRAL
|...|| . || |. .|.| . . . ||..... .. .|..||
VaVsGfppelielvlehFasfGeIvniyvpkevnwmylkyesekdaekAl
|
|||||||||
PP2C_SIG_SM00331 | 453-717 | 8e-09 | 28.4 | In-house | 19-181 (217) | alignment | |||
Range on Protein: 453-717
Range on HMM: 19-181/217.0
DGFLVYEGSSAlPFLAAVMDGHG--VNGRKVSGFAESTLGVEILESyrqnqalsEALVNGIVSTAA----KlrkstIDARESGTTAVVCARTPDGRQLIV
| . |.. . .|..| ||.| ... .|. . . | .. | |.|.. . . . . .....|.... . ...| .
Dyydvvklneg.rlllvvaDgmGkGlaAaaassqlrtalrellseg........eelsqalkrlnraiyee.....keekgmfaTlllalydfssgklsy
ANVGDSRCVLGRclGGSRYQPIPLsrdhkpsdpgerqriqraggyveptrvrgwgfqgparvwrrrqqegglalsrsvgdfhlfeagvvaepelqihagr
||.||||..| | | . ...
anaGdsrpyllr..dgklveilkd............................................................................
qylgrgpglwtrssiarhiayqhplTSDVPLGLDRKLE----KTLDSQDHFIVLGSDGVFDHL-----SNAQVILFLAKY
.. |||| ... .. ... ...| .||... .......|...
.........................vegaplGlepevsvdirelelekgdllllytDGltearsekgfaeerleeiledl
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PP2C_2 | Protein phosphatase 2C | 445-557 | 8.3e-08 | 24.8 | Pfam-A | 6-124 (212) | alignment | ||
Range on Protein: 445-557
Range on HMM: 6-124/212.0
AGNPKENQDGFLvYEGSSALPFLaAVMDGHGVN--GRKVSGFAESTLgVEILESYRQNQA-L-SEALVNGIVSTAAKL-------RKSTIDARESGTTAV
. . | .|| .. . .|. .| || ||.| ..| . .| ... .| ||.. .... .|||.. |.. . .. .. .... .|| .
rrkgkpcqDala.ireasdgwll.aVADGaGsakrSdkGarlaveaa.gealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTll
VCARTPDGrqLIVANVGDSRCVLG
....||.. ......||...|.
lavitpge..ivffqiGDgaivvr
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PP2C_2 | Protein phosphatase 2C | 445-557 | 8.3e-08 | 24.8 | In-house | 6-124 (212) | alignment | ||
Range on Protein: 445-557
Range on HMM: 6-124/212.0
AGNPKENQDGFLvYEGSSALPFLaAVMDGHGVN--GRKVSGFAESTLgVEILESYRQNQA-L-SEALVNGIVSTAAKL-------RKSTIDARESGTTAV
. . | .|| .. . .|. .| || ||.| ..| . .| ... .| ||.. .... .|||.. |.. . .. .. .... .|| .
rrkgkpcqDala.ireasdgwll.aVADGaGsakrSdkGarlaveaa.gealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTll
VCARTPDGrqLIVANVGDSRCVLG
....||.. ......||...|.
lavitpge..ivffqiGDgaivvr
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subfamily_Dicty-PPM-1_pd | Subfamily Dicty-PPM-1 | 528-596 | 3.1e-07 | 22.5 | In-house | 104-175 (276) | alignment | ||
Range on Protein: 528-596
Range on HMM: 104-175/276.0
SGTTAVVCARTPDG--------RQLIVANVGDSRCVLGRclGgsrYQPIPLSRDHKPSDPGERQRIQRAGGYVEPTR
|.|| .. || | | ||||||| | | | . . || ||| .|| |.|||. | . ..
eGatatlalvwsdGeeqqqqqqrylqvanvGdssaflsr..G...neslelskdhkatdpeekqrikddGitlsdnq
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subfamily_PPM1H_pd | Subfamily PPM1H | 495-588 | 8.9e-07 | 21.0 | In-house | 123-213 (404) | alignment | ||
Range on Protein: 495-588
Range on HMM: 123-213/404.0
ESYRQNQALSEALVNGIVSTAAK-----LRKSTIDARESGTTAVVCARTPDGrQLIVANVGDSRCVLGRCLGGsryqpIPLSRDHKPSdpGERQRIQRA
| |.... .| || | . .| . ... . | .| ... | . .| .| ||| |||| .| |. ||||.|. | ||||.|.
eiyeekeiskeeLviGalesaflemDeqiarereayrikGGCtalvalvllg.klYvanaGDsRailvrkdei.....iplsadftPe..teRqRlqel
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subfamily_PP2D1_pd | Subfamily PP2D1 | 543-594 | 4e-06 | 18.8 | In-house | 189-235 (492) | alignment | ||
Range on Protein: 543-594
Range on HMM: 189-235/492.0
QLIVANVGDSRCVLGRClgGSRYQpipLSRDHKPSDPGERQRIQRAGGYVEP
| .||.|. . || | |. .. | |.| | .. ||.|...||. |
vlyianaGnvqAvLcre..Gkaii...LtreHtprnkkERtRvekagsvvvk
|
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PP2C | Protein phosphatase 2C | 686-714 | 9.7e-06 | 18.3 | Pfam-A | 197-225 (255) | alignment | ||
Range on Protein: 686-714
Range on HMM: 197-225/255.0
TLDSQDHFIVLGSDGVFDHLSNAQVILFL
.|...|.|..|.|||..|.||. ... .
klteedefliLasdGlwdvlsdqeavdlv
|
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PP2C | Protein phosphatase 2C | 686-714 | 9.7e-06 | 18.3 | In-house | 197-225 (255) | alignment | ||
Range on Protein: 686-714
Range on HMM: 197-225/255.0
TLDSQDHFIVLGSDGVFDHLSNAQVILFL
.|...|.|..|.|||..|.||. ... .
klteedefliLasdGlwdvlsdqeavdlv
|