Gene PTC7 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PTC7
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP136_AA protein Get Run
MbreP136_AA_208-422 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPTC7_pd Subfamily PPTC7 207-447 3.3e-72 235.9 In-house 7-238 (252) alignment 
Range on Protein: 207-447
Range on HMM: 7-238/252.0
QGYAGEDAYAISHETGPLHGlFLADGVHAWHSEGIDAGAWARELTlglahqhdSAASAYAKAPLAERVRPgltlVEMVEHVYQQLLTDGVQ--GSSTLVS
.  ||||||..|.|... .  ..||||..|.|.|||.....|||.        .|.....|.. ||...|    ||..|..||.||...|.  ||||...
rqkageDayfvsseksadvl.gvADGVggWrsvGiDpsefsreLm........kaceklskeskaeelkP....velleaayqelleekvpvlGssTaci

ACFDGSTGALDVYNLGDSGLSVLRRRgtiggadvyGVLYRTPVLEHRFGCPYQLGHHAQG-------DTPEAGLVKTLALQPDDIVVMGSDGLWDNLLPS
...|.|...|...||||||..|.|..          |..|.....|.|..||||.....|       |.|||. .|..|....||.|...|||.||||..
vvldksdkklesanlGDSgflvvRkg.........kvvfrskeqqhkfntPyQLsiapegregkvildkpeaadsksfavkkgDiivlatDGlfDNlled

DMARI-----CSEPSSRRTLHHRLAAAAFNVSLDRNADSPFAREATEElNMFYSG
....|     .||.||...|...||..|...||| ...||||..| .. .. .||
eileilkelkeseksslqslakklaekarelsldpeyespfaqkakkn.gleasG
LIM LIM domain 502-557 7e-17 49.4 Pfam-A 1-57 (58) alignment 
Range on Protein: 502-557
Range on HMM: 1-57/58.0
CQVCSKPVYYMEKL-EADEKVYHKTCFKCSVCKKSLSAGTYAAMSGVLYCKPHFKQM
|. | |...  | . .| .||||. ||.||.|.|.|. ...  . | |||| .. ..
CagCnkkiadrelvlkalgkvyHeeCFtCseCqkplkeksffekdgklyCkkdylkk
0049733 PP2C-like 209-422 1.1e-15 50.9 In-house 16-219 (235) alignment 
Range on Protein: 209-422
Range on HMM: 16-219/235.0
YAGEDAYAIshetgPLHGLFLADGVHawhseGIDAGAWARELTLGLAHQHDSAasaYAKAPLAERVRPGLTLVEMVEHVYQQLLTDGVQGSSTLVSACFD
  .|||...      |. . .|||.      |  ||..|.||.. . ...  .   .    |.|..|  .. .. . . ...   .   . .|.| |..|
kvneDavlv.....glllfavaDGhg.....ghaagevasellvetllellle...lllldleealrkaflaaneallelalaspelagmgtTavvalld

gsTGALDVYNLGDSGLSVLRrRGTiggadvygVLYRTPVLEHRFGCPYQ--------------------L-----GhhaqgdtpeaGLVKTLALQPDDIV
  .| | | |.||| . .|| .|.        ....|    . . ...|                    |                  | .| |.|.|..
..ggklyvanvGDsrayllr.dgk........lvqltedhspvnelerqriitaggavrvpgrlaltralGdlllk..........pdvtvlelepgdfl

VMGSDGLWDNLLPSDMARICSEpSSRRTLHHRLAAAAFN
.. ||||||.| ..........  . . . .||. .|..
llasDGlwdvlsdeeivdllrs.ldleeaaerlvelala
PLAT PLAT/LH2 domain 45-149 5.3e-11 30.4 Pfam-A 3-104 (113) alignment 
Range on Protein: 45-149
Range on HMM: 3-104/113.0
FDILTSDARAAGCECNALVKVEGSRNSFEGRLHPKSGLFERGQREIFRERC-DDLGRIRALVIGPDRPGKDDGWLLNSVILRIldddNRLRRVFTFECNR
. | |.|.. || . |  ....||. . . . . . .|...|. . |.  . .|||.. |. .. .  | .|.|.|.... .        .. .|| ||.
vkivtgdetgagtdanvyislygskgksgeipllepelkndgstdeftfdtdedlGdlgaiklkneisghsdewflkrilVkd....getggtvtFpcns

WLGGRH
|... .
wvdnde
0034914 PP2C-like 209-421 6.3e-11 34.9 In-house 33-275 (295) alignment 
Range on Protein: 209-421
Range on HMM: 33-275/295.0
YAGEDAYAISHE----TGPLHGLFLADGVHAWHSEGIDAGAWARELTLGLAHQhdSAASAYAKAPLAERVRPGLTLVEMVEHVYQQLLTDGVQGSSTLVS
   |||. . ..    ...|. . ..||.  ..   . .    ..|   | ..     . .    ..| .| ..  ..   . . .|  .   ...|.| 
ksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekl..lllltlsledieealrkaflaadeellelallrpelagsGtTavv

ACFDGSTgaLDVYNLGDSGLSVL--------------------RRRGTIGGADVYGVLYRTPVLEHRFGCPYQLGHHAQG-------DTPEAGlVKTLAL
| . |..  | | |.|||   .|                    .|  . ||| ..| .. . ..   .|  ... ..           .|.   | .| |
alirgnk..lyvanvGDSravllrngelvqltvdhkpvnelererilsaggavshgrvngvlavtRalGdfdlklllslllleplvsaePdvt.vleltl

QPDDIVVMGSDGLWDNLLPSDMARICSE----PSSRRTLHHRLAAAAF
..||.....||||||.| ......|...      .   . ..|. .|.
edddfllLasDGlwdvlsneeivdivrsllakgldleeaaeeLvdlAl
PPM_PTC7_SpoIIE 270-393 4.2e-09 29.5 In-house 58-169 (230) alignment 
Range on Protein: 270-393
Range on HMM: 58-169/230.0
LAERVRPGL-TLVEMVEHVYQQLLTDGVQG----SSTLVSACFDGSTGALDVYNLGDSGLSVLRRRGTiggadvygvlyrTPVLEHRFGCPYqLGHHAQG
|.|. ..|| .. | ... ...| .|         .|.| |..|.||| | | |.|||   ..|  |.            .  .   .| |. ||   . 
lrelafaglekpeeilrrlnlalaadledepsssgaTavvalidpstgklyvanaGdsppllvrddgg............ererivagglps.lGilpgr

DTPEaglvKTLALQPDDIVVMGSDGLWDN
. ..     ...|.| |. .. .||. ..
vfgv....lavslapGdllllytDGvvea
PP2C_SIG_SM00331 211-413 6.8e-09 28.6 In-house 17-190 (217) alignment 
Range on Protein: 211-413
Range on HMM: 17-190/217.0
GEDAYAISHETGPLHGLFLADGVHawhsEGIDAGAWARELTLGLAHQHDSAasayakaplaerVRPGLTLVEMVEHVYQQllTDGVQGSSTLVSACFDGS
..| | .    .  . | .|||.      |..|.| ...|   | .. ..               .  .| .. . .|..  ..  ..  ||. |..| |
sGDyydvvklnegrlllvvaDgmG....kGlaAaaassqlrtalrellseg............eelsqalkrlnraiyee..keekgmfaTlllalydfs

TGALDVYNLGDSGLSVLRRRGTIGGADVygvlyrtpvlehrfGCPYQLGHHAQGDtpeaGLVKTLALQPDDIVVMGSDGLWDNLLPS------DMARICS
.| | ..|.|||   .|| ....   .                 ...||.. . .      ...| |...|.... .|||...  .       ..  ...
sgklsyanaGdsrpyllrdgklveilkd..............vegaplGlepevs....vdirelelekgdllllytDGltearsekgfaeerleeiled

EP-SSRRTLH
   |. . |.
lvdseaqela
SpoIIE Stage II sporulation protein E (SpoIIE) 270-397 2.1e-08 26.2 Pfam-A 30-139 (193) alignment 
Range on Protein: 270-397
Range on HMM: 30-139/193.0
LAERVRPGLTLVEMVEHVYQQLLTDGV--QGSSTLVSACFDGSTGALDVYNLGDSGLSVLRRRGtiggadvygvlyRTPVLEHRFGCPyqLGHHAQgdtp
| | .. ||.. |..|.... | ..    .   |.| | .| ||| | . |.|..   ..|. |            .| .|.. .| |  ||  ..    
lrelataglepaevlerlnealarnleeeerfatavlaeydpstgkleyanaGhpppllvrpdg............gtkfllvstglp..lGilpe....

EAGLVKTLALQPDDIVVMGSDGLWDNLlpS
.   ...| |.|.|.... .||. ..   .
adyeeaelqlepgdllllyTDGvtEar..d
SpoIIE Stage II sporulation protein E (SpoIIE) 270-397 2.1e-08 26.2 In-house 30-139 (193) alignment 
Range on Protein: 270-397
Range on HMM: 30-139/193.0
LAERVRPGLTLVEMVEHVYQQLLTDGV--QGSSTLVSACFDGSTGALDVYNLGDSGLSVLRRRGtiggadvygvlyRTPVLEHRFGCPyqLGHHAQgdtp
| | .. ||.. |..|.... | ..    .   |.| | .| ||| | . |.|..   ..|. |            .| .|.. .| |  ||  ..    
lrelataglepaevlerlnealarnleeeerfatavlaeydpstgkleyanaGhpppllvrpdg............gtkfllvstglp..lGilpe....

EAGLVKTLALQPDDIVVMGSDGLWDNLlpS
.   ...| |.|.|.... .||. ..   .
adyeeaelqlepgdllllyTDGvtEar..d