Gene PHP in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PHP
Superfamily PHP
Family PHP
Subfamily PHP
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP135_AA protein Get Run
NvecP135_AA_10-125 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
PHP 11-125 1.2e-49 157.3 In-house 2-121 (121) alignment 
Range on Protein: 11-125
Range on HMM: 2-121/121.0
KLDAIPDVDIDESGIFKYILLKITD------GDKEKNIVRGYEWADFHADIYERVQPGIEELGLGTECVGGGRIRHNAAKKKILVYGFSMGFGRADHKIS
.|...||||||. |.|||.|...|.      ....|..||||..|..|||||.||.  .|. || .||.|||||.|.  .||| |||.|.|.|.|||...
elakvpdvdidpeGvfkyvlirvtskerkdgaaaskevvrGyaraeyhadiydrvsselekqgldaeclGGGriehdseekkikvyGysvgyGkadhavt

VAKLKAVYPNYtEITFSNDGY
. |||. ||.| |||.|..||
keklktkyPdy.eitlsdeGy
subfamily_PHP_pd Subfamily PHP 13-123 9.4e-48 150.8 In-house 2-114 (114) alignment 
Range on Protein: 13-123
Range on HMM: 2-114/114.0
DAIPDVDIDESGIFKYILLKI---TDGDKEKNIVRGYEWADFHADIYERVQPGIEELGLGTECVGGGRIRHNAAKKKILVYGFSMGFGRADHKISVAKLK
.|.|.||||..| |||.|...   ..|.|.|.|||||..|..||||||.|.. .|.||| ..|.|||||.|.. |||| |||.|.|||.|||.|.. .||
aavpevdidskGkfkYvlielttdsegkksktivrgyskaeyhadiyeevkeeleklglkakclGGGriehdkekkkikvyGyskgfGkadheiakeilk

AVYPNYtEITFSND
..||.| .||.||.
tkypdy.kitisne
Ocnus Janus/Ocnus family (Ocnus) 12-116 5.6e-43 135.1 Pfam-A 1-107 (108) alignment 
Range on Protein: 12-116
Range on HMM: 1-107/108.0
LDAIPDVDIDESGIFKYILLKITD--GDKEKNIVRGYEWADFHADIYERVQPGIEELGLGTECVGGGRIRHNAAKKKILVYGFSMGFGRADHKISVAKLK
|...|.|||||.|.|||.|.|...  .|..|..|||...|..||||||.|.  .|.||| |||.|||||.|...|||| ||| |.|||.|||.|....||
LakvpevdideeGkfkYvlikvkikekdeskevvrglkkaeyHadiyekvkkeleklgleteclGGGriehdeekkkikvyGyskgfGkadheiakeilk

AVYPNYT
. |..|.
kkykdye
Ocnus Janus/Ocnus family (Ocnus) 12-116 5.6e-43 135.1 In-house 1-107 (108) alignment 
Range on Protein: 12-116
Range on HMM: 1-107/108.0
LDAIPDVDIDESGIFKYILLKITD--GDKEKNIVRGYEWADFHADIYERVQPGIEELGLGTECVGGGRIRHNAAKKKILVYGFSMGFGRADHKISVAKLK
|...|.|||||.|.|||.|.|...  .|..|..|||...|..||||||.|.  .|.||| |||.|||||.|...|||| ||| |.|||.|||.|....||
LakvpevdideeGkfkYvlikvkikekdeskevvrglkkaeyHadiyekvkkeleklgleteclGGGriehdeekkkikvyGyskgfGkadheiakeilk

AVYPNYT
. |..|.
kkykdye
0053050 PHP14-like 12-116 2.1e-42 132.9 In-house 2-113 (118) alignment 
Range on Protein: 12-116
Range on HMM: 2-113/118.0
LDAIPDVDIDESGIFKYILLKIT-------DGDKEKNIVRGYEWADFHADIYERVQPGIEELGLGTECVGGGRIRHNAAKKKILVYGFSMGFGRADHKIS
| ..|.|||||.|.|||.|.|.|       .|...| ||||. .|..||||||.|.. .|.||| .||.|||||.|.  |||| |||.|.|||.|||.|.
lakvpevdideeGvfkYvlikvtlkgltdsggkesklivrglkkaeyHadiyeevskeleklgldleclGGGriehdsekkkikvyGyslgfGkadheia

VAKLKAVYPNYT
...|| .||.|.
leilktkypdye