Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_PDP_pd | Subfamily PDP | 107-498 | 3.6e-160 | 526.4 | In-house | 1-398 (398) | alignment | ||
Range on Protein: 107-498
Range on HMM: 1-398/398.0
ETNQLASNQPMEDRKFVVRLLHQDgGYLFGVMDGHGGNACAHNVCKRLPDYIALSLLHRHVLLAHPDLMPKLTDYLTITKNEDHCYNYANDPACRNSLNK
..||||||.|.|||.....||... |.||||.|||||.|||..|.|||..|.|.|||...|| .. . ... ...|...|...|......| |...||..
dsnqLasNePiEDrrseakllesn.gvlfgvfDGHggaacaeavskrLlkyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslse
YFYELQDMVEAHVEMHVRSIREAYIRLDQDIRNEAVKESksklPEGSSCHAFDAANAGACALVAYIQGTELFLANAGDCRAVLGVQGEDGCWSAMQLSSD
. ..||...||.||.. .....|. .||.||..||.|.. .| |...|...| .|||||.|.|.||||..||.|||||||||| |.|.|.|..||.|
lskylqelleaevekvkealkkaFlklDkdistealkkl....kekslreallvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskd
HTAGNPEEVQRILNQHPPEESTTVIRFERLLGRLAPLRAFGDARFKWDKKTQNKVYSKSSlNPMSEVEHFYTPPYLTAEPEVMSYQLQRTDKFLVLATDG
.|| |.|||.|| ..|| |||.|||| .||||.|.|||||||.|.||....|.||..|.. ....|.....|||||||||||.|..|...||||||||||
qtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwseelqkkvlekay.lkvlepkdyktPPYltaePevtshklrendkFLvlatDG
LWDMLSNEEVVHYVQEHVCKKVEDTSKGVLPQDITFN-----EQELPCDL----NNAASCLVREALGGD---DHVAVSTTLSIPYPDVRMYRDDISVIVV
|||.|||||||..|.||..|| |... .| ....|.. ..| ..| .|||..|.|.||||. |. .||..||||.. .|||||||.|.||
LwdllsneevvslVgehlakkkekepvkveeakltlkqvveelkerkrklkredknaAthLirhalggneagdkekvsallsiPeelaRmyRDDitvtVv
FFNW
|||.
ffns
|
|||||||||
| PP2Cc_SM00332 | 106-494 | 4.5e-61 | 199.6 | In-house | 14-274 (274) | alignment | |||
Range on Protein: 106-494
Range on HMM: 14-274/274.0
YeTNQLASNQPMEDRKFVVRLL-HQDGGYLFGVMDGHGGNACAHNVCKRLPDYIALSLLHRHVLLahpdlmpkltdyltitknedhcynyandpacrnsl
. ... ....|||. .|| | ..... .||| |||||...| |.|.||.... .| |
k.ssmqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel...................................
nkyfyelqdmveahVEMHVRSIREAYIRLDQDIRNEAVKESKSKlpegsschafdaANAGACALVAYIQGTELFLANAGDCRAVLGVQGEdgcwsAMQLS
.. . ...|. ..|..|. |. .. . . |..|..|.||.... |..||.||.||||. .|. | |||
..............eddveealkkaflstdeeileeeqskelen............alsGstavvallkkedlyvanvGDSravlcrngk.....avqls
SDHTAGNPEEVQRILNQHPpeesttVIRFERLLGRLAPLRAFGDARFKWDKktqnkvysksslnpmsevehFYTPPYLTAEPEVMSYQLQRTDKFLVLAT
||.. ...|..|| .... |....|. | || ||||| .|. | ..||.||||.| .| |.||.||.
vdhkpedederkRikkagg......vvekgrvngglavsrafGdhflkknk....................klkepyitaepdvkvvtltsedeflilaS
DGLWDMLSNEEVVHYVQEHVCKKvedtskgvlpqditfneqeLPCDLNNAASCLVREALGGddhvavsttlsipypdvRMYRDDISVIVV
|||||.|||.||| .|... |. | .|| |..||. ....|.|.|.||
DGlwdvlsnqevvdivrkllakg...................ktndpqeaaelldeeairr.................ggseDniTvvvv
|
|||||||||
| 0034914 | PP2C-like | 114-497 | 2.4e-59 | 193.5 | In-house | 32-291 (295) | alignment | ||
Range on Protein: 114-497
Range on HMM: 32-291/295.0
NQPMEDRKFVVRLL--HQDGGYLFGVMDGHGGNACAHNVCKRLPDYIALSLLHRHVLLAHPdlmpkltdyltitknedhcynyandpacrnslnkyfyel
. ..||. .||. | ......|||| ||||| |.|. ....|..... | . ..|| ..
rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltls.......................................
qdmveahVEMHVRSIREAYIRLDQDIRNEAVKEsksklpegsschaFDAANAGACALVAYIQGTELFLANAGDCRAVLGVQGedgcwSAMQLSSDHTAGN
|. ....|.|....|......|... . |. |..|.||.|.|. |..||.||.|||| .| ..||. ||. |
.......ledieealrkaflaadeellelallr.............pelagsGtTavvalirgnklyvanvGDSravllrng.....elvqltvdhkpvn
PEEVQRILNQHPpeesttVIRFERLLGRLAPLRAFGDARFKWDKKTqnkvysksslnpmsevehFYTPPYLTAEPEVMSYQLQ-RTDKFLVLATDGLWDM
..|..|||. .. .....|..| || ||.|| ..|. .. ....|...|||.|....|. |.||.||.|||||.
elererilsagg......avshgrvngvlavtRalGdfdlklllsl..................llleplvsaePdvtvleltledddfllLasDGlwdv
LSNEEVVHYVQEHVCKKVEdtskgvlpqditfneqelpcdLNNAASCLVREALGgddhvavsttlsipypdvRMYRDDISVIVVFFN
|||||.|..|.... | . |..|| ||..|| |..||.|.|.||..|
lsneeivdivrsllakgld.....................leeaaeeLvdlAla..................rgsrDNiTvvvvrln
|
|||||||||
| PP2C | Protein phosphatase 2C | 210-427 | 6.7e-41 | 133.5 | Pfam-A | 47-232 (255) | alignment | ||
Range on Protein: 210-427
Range on HMM: 47-232/255.0
ELQDMVEAHVEMHVRSIREAYIR-LDQDIRNEAVKE-SKSKLPEgSSCHAfDAANAGACALVAYIQGTELFLANAGDCRAVLGVQGEDGcwsaMQLSSDH
|.... . |.| .. . .. . ..... .... . ...| |.... . |..|.||.|.|..|..||.||.||||. .... .|. ||
eaakyarehleeilkeqksflelekvekalrksfladtdeelks.skant.epsksGstavvalirgkklyvAnvGDSravLcrkdnak....keltedH
TAGNPEEVQRILNQHPPEESttvirFERLLGRLAPLRAFGDARFKWDKktqnkvysksslnpmsevehfytPPYLTAEPEVMSYQLQRTDKFLVLATDGL
.. ...|..|| ... . . |. | || ||.|| ..| .. ... .|||.| | .|.. |.||.||.|||
kpsdedEreRIeeaggsvsn.....ngrvngsLavsRalGdfelkpke.......................eqlvsaePdvtsvklteedefliLasdGl
WDMLSNEEVVHYVQEHVCKK
||.||..|.|. |.... ||
wdvlsdqeavdlvrselskk
|
|||||||||
| PP2C | Protein phosphatase 2C | 210-427 | 6.7e-41 | 133.5 | In-house | 47-232 (255) | alignment | ||
Range on Protein: 210-427
Range on HMM: 47-232/255.0
ELQDMVEAHVEMHVRSIREAYIR-LDQDIRNEAVKE-SKSKLPEgSSCHAfDAANAGACALVAYIQGTELFLANAGDCRAVLGVQGEDGcwsaMQLSSDH
|.... . |.| .. . .. . ..... .... . ...| |.... . |..|.||.|.|..|..||.||.||||. .... .|. ||
eaakyarehleeilkeqksflelekvekalrksfladtdeelks.skant.epsksGstavvalirgkklyvAnvGDSravLcrkdnak....keltedH
TAGNPEEVQRILNQHPPEESttvirFERLLGRLAPLRAFGDARFKWDKktqnkvysksslnpmsevehfytPPYLTAEPEVMSYQLQRTDKFLVLATDGL
.. ...|..|| ... . . |. | || ||.|| ..| .. ... .|||.| | .|.. |.||.||.|||
kpsdedEreRIeeaggsvsn.....ngrvngsLavsRalGdfelkpke.......................eqlvsaePdvtsvklteedefliLasdGl
WDMLSNEEVVHYVQEHVCKK
||.||..|.|. |.... ||
wdvlsdqeavdlvrselskk
|
|||||||||
| 0049733 | PP2C-like | 114-497 | 4.1e-40 | 130.6 | In-house | 15-234 (235) | alignment | ||
Range on Protein: 114-497
Range on HMM: 15-234/235.0
NQPMEDRKFVvrllhqdGGYLFGVMDGHGGNACAHNVCKRLPDYIALSLLHrhvlL---Ahpdlmpkltdyltitknedhcynyandpacrnslnkyfye
.. .||. .| |..||.| ||||| |... . ..|..... ||. |
rkvneDavlv.......glllfavaDGhgghaagevasellvetllellle....lllld........................................
lqdmveahvemHVRSIREAYIRLDQDIRNEAVKESksklpegsschafDAANAGACALVAYIQGTELFLANAGDCRAVLGVQGEdgcwsAMQLSSDHTAG
....|.|. .... ....|... . | |..|.||...| |..||.||.||.| .|. ..||. ||.
...........leealrkaflaaneallelalasp.............elagmgtTavvalldggklyvanvGDsrayllrdgk.....lvqltedhspv
NPEEVQRILNQHPPEesttvirfeRLLGRLAPLRAFGDARFKwdkktqnkvysksslnpmsevehfytppyltaePEVMSYQLQRTDkFLVLATDGLWDM
|..|.|||.. .. | .|||| .||.|| .| |.|....|. | ||.||.|||||.
nelerqriitaggav.........rvpgrlaltralGdlllk.................................pdvtvlelepgd.flllasDGlwdv
LSNEEVVHYVQEhvckkveD-TskgvlpqditfneqelpcdlNNAASCLVREALGgddhvavsttlsipypdvRMYRDDISVIVVFFN
||.||.|..... . ..||..||..|| | ||.|.|.||...
lsdeeivdllrs.......ldl....................eeaaerlvelala..................rggrDNiTvvvvrld
|
|||||||||
| PPM_PTC7 | 225-427 | 4.4e-39 | 127.5 | In-house | 75-237 (259) | alignment | |||
Range on Protein: 225-427
Range on HMM: 75-237/259.0
SIREAYIRLDQDIRNEAvkesksklpegSSCHAfDAANAGACALVAYIQGTELFLANAGDCRAVLGVQGEDGcwsaMQLSSDHTAGNPEEVQRILNQHPP
.|... .||.|.... |.... . |..|.||.|.|..|. ||.||.||||. .|.. ||. ||.. |..|..|| . .
alrksflaldtdeelks...........seant.epstsGstAvvalitgsklyvAnvGDSravLcrsgnav....kqltedHkpsnedEreRiegaggs
EESTtviRFERLLGRLAPLRAFGDARFKWDKKtqnkvysksslnpmsevehfyTPPYLTAEPEVMSYQLQRTDKFLVLATDGLWDMLSNEEVVHYVQEHV
.. .. |. | || ||||| ..| ... ......|||.. | ... |.||.||.|||||..|..|.|. |....
vsnv...gngrvngvlavsRafGdfelkpket.....................eeqlvsaePdisstkideedefliLasdGlwdvvsdqeavdlvrsel
CKK
||
skk
|
|||||||||
| subfamily_PPM1A_pd | Subfamily PPM1A | 115-497 | 1.4e-37 | 122.6 | In-house | 24-281 (282) | alignment | ||
Range on Protein: 115-497
Range on HMM: 24-281/282.0
QPMEDRKFVVRLLHQD-GGYLFGVMDGHGGNACAHNVCKRLPDYIALsllhrhvllahpdlmpkltdyltitknedhcynyandpacrnslNKYFYElQD
. |||. || | . .. .| |.|||.|. .|. | | |.. | .. . | .
vemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenile............................................eeelke.aa
MVEAHVEMHVRSIREAYIRLDQDIRNEAVKESKS-KLpegsschafdaanaGACALVAYIQGTELFLANAGDCRAVLGVQGedgcwSAMQLSSDHTAGNP
. . . . . .|.....||..||.. . ... | |. |... .. ..|..||.||.|||| .| .|. |..|| . .|
leasekdevkealrqgfLaldeairelstdlktadks..............GsTavtvlvsekhliianlGDsRavlcrng.....kaaflteDHkpsrp
EEVQRIlnqhppEESTTVIRFERLLGRLAPLRAFGDARFKWDKKTQNKvysKSslnpmsEvehfytppyLTAEPEVMSYQLQRTDKFLVLATDGLWDMLS
.| .|| |. . .|. | || ||.|| .| ... ... . ..|||||.| . . |.||||| ||.||.||
kEkkRi......eqAGGsvvvsRvnGaLAvsRalGDyeykeeeekkae...eq......l.........vsaepevtsierseeddflvlacDGiwDvls
NEEVVHYVQEHVCKKvEDTSKGvlpqditfneqelpcdlnnaasclvrealggddhvaVSTTLSIPYpdVRMYRDDISVIVVFFN
.||||..|.... .. .. .. ... . . . || .||.||.|.
deevvelvrkrleva.deleev....................................akalvdkal..ekgsrDNlsvlvvlfa
|
|||||||||
| subfamily_PPM1G2_pd | Subfamily PPM1G2 | 126-429 | 1.8e-34 | 112.0 | In-house | 46-252 (287) | alignment | ||
Range on Protein: 126-429
Range on HMM: 46-252/287.0
LLHQDGGYLFGVMDGHGGNACAHNVCKRLPDYIALsllhrhvllahpdlmpkltdyltitknedhcynyandpacrnslnkyfyelqdmveahvE-----
. .. ||.|.|||||...|. . |.| .||
ksddkslalfavfDGhGGakvakyagkklikkiak...........................................................kksfke
-MHVRSIREAYIRLDQDIRNEavkesksklpegsscHAFDAANAGACALVAYIQGTELFLANAGDCRAVLGVQGEdgcwsAMQLSSDHTAGNPEEVQRIL
. . ...|....|...... .... .||. |.|. |. ..|. ||||| |||| ..|. . .|| || . .| .||
galeqilkdafletDeellkd...............eklkdesaGstavvvlikeeklyvanaGDsravlsskgn.....vkalsfDhkPqeesekkrii
NqhppeeSTTVIRFERLLGRLAPLRAFGDARFKWDKKtqnkvysksslnpmsevehfyTP---PYLTAEPEVMSYQLQRTDKFLVLATDGLWDMLSNEEV
. . .. ..| | || ||.|| || .| .. ||.|.|. .|. | ||||| ||.||.|.|.||
a......agGfvelnrvngnLalsralgDfefkknvk.....................kkpeeqivtavPDvlvkkldeddeflvLaCDGiWDvltnkev
VHYVQEHVCKKVE
|..|.|.. .. .
vdlvrerlvsgak
|
|||||||||
| subfamily_PPM1G_pd | Subfamily PPM1G | 239-430 | 1.4e-25 | 83.2 | In-house | 271-435 (473) | alignment | ||
Range on Protein: 239-430
Range on HMM: 271-435/473.0
NEAVKESKS-KLPEGSSCHAFDAANAGACALVAYIQGTELFLANAGDCRAVLGVQGEdgcwsAMQLSSDHTAGNPEEVQRILNQhppeeSTTVIRFERLL
.| ..... . .|| . ..|. | || ... .|. |||||.|.|| .|. |..|| || ...| .|| . .| |.
eedgegeeakeeldgseekeepGedsGttAvvaLlkekklivAnaGDsRcvlsrnGk.....AldlslDHkPeDevEleRiekA.....GGkvdedgRvn
GRLAPLRAFGDARFKWDKKTQNKVYSksslnpmsevehfytppyLTAEPEVMSYQLQRTDKFLVLATDGLWDMLSNEEVVHYVQEHVCKKVED
| | ||.|| .| ... ..| ..| |.. .|. |.|||||.||.|.... .||| .|.... |. |.
GGLnlsRAlGDhaYkkneeLplkeqm..................isAlPDikvltlteedeFlvlAcDGiWnvmesqevvdfvraklkkgees
|
|||||||||
| PPM_PTC7_SpoIIE | 225-441 | 4.3e-20 | 65.5 | In-house | 72-223 (230) | alignment | |||
Range on Protein: 225-441
Range on HMM: 72-223/230.0
SIREAYIRLDQDIRNEavkesksklpegsschafdAANAGACALVAYIQGTE--LFLANAGDCRAVLGVQgEDGcwsamqlssdhtagnpeEVQRILNQH
.|... .|..|...| .. ||.|.||.|... | .|||||....| . ..| |. ||
ilrrlnlalaadlede...................psssgaTavvalidpstgklyvanaGdsppllvrd.dgg.................ererivagg
PPE----ESttvirfeRLLGRLAPLRAFGDARFKWdkktqnkvysksslnpmsevehfyTPPYLTAEPEVMSYQLQRTDKFLVLATDGLWDMLSNEEVVH
.|. . | | || .|.|| .. | . .|||. . | . |.||.||.|||||.||..|.|.
lpslGilpg.......rvfgvlavslapGdlllly........................tDGvveaepdtsdgelfgkdeflilasdglwdvlspqelvd
YVQEHVCKKvedTSKGVLPQDIT
|.... |. ..| | |||
lvrdelekp...aaeglleDDit
|
|||||||||
| subfamily_TAB1_pd | Subfamily TAB1 | 112-412 | 1.1e-17 | 56.8 | In-house | 9-261 (333) | alignment | ||
Range on Protein: 112-412
Range on HMM: 9-261/333.0
ASNQPMEDRKFVVrlLHQDGGYLFGVMDGHGGNACAHNVCKRLPDyialSLLHrhvllahPDLMPKLTDYLTITKnedhcYNYandpACRNSLNKYFYEL
....||. |.. ... .|..| ||. || |. | .||. || ..|...|... . .. | . .|.. ..
kedhevedkvflf..ktendpilyavFdGydGnkaakfveqrLva....elll.......eqltdelaeaevkev.....lkr....afeeverkflesi
QDMVEAHVEMHVRsireayirLDQDIRN-EAVKESKSKLPEGSSCHafDAANAGACALVAYIQGTELFLANAGDCRAVLGVQGEdgCWSAMQLSSDHTAG
.|... . ... . | ... . |. .....|. .. . . . |. |.|| | .|. ||.|| ||.| . | |||.|||
ddalaekddlqsq........lPegvssyeleeqypekierlqele..eeisgGttAvvalifnnkLyVaNvGdsrAllvkrke..sekvkqLsvdHttd
NPEEVQRILNQHPpeeSTTVIRFERLLGRLAPLRAFGDARFKWDKKtQNKVYSKSSLNPMsevehfytppylTAEPEVMS-YQLQRTDKFLVLATDGLWD
|..|..|. . . |. ..|| . |. || . | | .....|... .|. |||.. |... . .|||| ||.
NedEllRlkdLGl...dieqikrnkrlgskentRsiGdykvkkgyk.dvdilssakgePv............iaePdiqgaypiddityflvlmSdGvyk
MLS
|
tLe
|
|||||||||
| subfamily_PPM1D_pd | Subfamily PPM1D | 133-319 | 2.5e-13 | 42.8 | In-house | 36-165 (309) | alignment | ||
Range on Protein: 133-319
Range on HMM: 36-165/309.0
YLFGVMDGHGGNACAHNVCKRLPDYIALSllhRHVLLAHPDLMpkltdyltitknedhcynyandpacrnslnkyfyelqdmveahvemhVRSIREAYIR
..|.|||||. |. . ..| .| ...| .|. . .. ||||..
afvavfDGHGGkeAakfarehlwsvikkq...kkflssepedv...............................................leAireafla
LDQDIRneavkESKSKLPEGSSCHafdAANAGACALVAYIQGTELFLANAGDCRAVLGVQGE-DGCWSAMQLSSDHTAGNPEEVQRIL
. . .. ..... |. | . . ||. | | |....|..|. || ..||||. . . . | .| .|| .|||..||
theamk.....kkleeWpktksgl...lstaGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerie
|
|||||||||
| subfamily_PPM1E_pd | Subfamily PPM1E | 380-432 | 9.2e-13 | 41.0 | In-house | 184-236 (265) | alignment | ||
Range on Protein: 380-432
Range on HMM: 184-236/265.0
PYLTAEPEVMSYQLQRTDKFLVLATDGLWDMLSNEEVVHYVQEHVCKKVEDTS
||...|..|....|. ....|.||.|||||.. .||||. |.|.. ...||.|
pyvsgeadvaeveldgseeylilacDGlwDvvneeevvklveefladgaedls
|
|||||||||
| subfamily_PPM1L_pd | Subfamily PPM1L | 115-352 | 9.7e-13 | 41.0 | In-house | 17-188 (269) | alignment | ||
Range on Protein: 115-352
Range on HMM: 17-188/269.0
QPMEDRKFVVRLLHQD-GGYLFGVMDGHGGNACAHNVCKRLPDYIALSLLHRhvllahpdlmpkltdyltitknedhcY-------Nyandpacrnslnk
. |||| . .... | .|.|.|||||. |. . ..|.. | |..
prmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknkliel..........................dadkentep.............
yfyelqdmveahvemhvrsireayIRLDQDIRNEAVKeSKSKLPEGSScHAfdAANAGACALVAYIQGTELFLANAGDCRAVLgvqgEDGCWSAMQLSSD
| .. . .| . || | .| ||. ||.| .|...| .|| || | || | |. || |
........................infsklltdeils.vdekllekak.ra..ediaGttalialvqesdlivanvGdsrGvl....ydkrGkaiplsfd
HTAGNPEEVQRILNQHPPEESTTVirfERLLGRLAPLRAFGDARFK
| ...| .|| . | |. | || ||.|| .|
hkpqqvkerkrikkaGGfiafrGv...wrvaGvlatsralGdyplk
|
|||||||||
| subfamily_PPM1H_pd | Subfamily PPM1H | 376-428 | 9.6e-12 | 37.3 | In-house | 299-355 (404) | alignment | ||
Range on Protein: 376-428
Range on HMM: 299-355/404.0
FYTPPYLTAEPEVMSYQLQR----TDKFLVLATDGLWDMLSNEEVVHYVQEHVCKKV
. |.|...|||. ..|. .|. |.||||||||.|||||| . |.| . |
lsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskve
|
|||||||||
| subfamily_PPM1K_pd | Subfamily PPM1K | 213-352 | 3.2e-11 | 35.9 | In-house | 47-182 (263) | alignment | ||
Range on Protein: 213-352
Range on HMM: 47-182/263.0
DMVEAHVEMHVRSIREAYIRLdQDIRNEAVKESKSKLPEGSSCHAF--DAANAGACALVAYI-QGTELFLANAGDCRAVLGVQGEdgcwsAMQLSSDHTA
| | ..| ... . | | . . ..| .| . || . . ..|. | |. . .|||| ||. || ||.| .|. |..|..||.
dfvhdklekilkrllekekdl.eivlknafeeldkklkrylefsvaeaellssGttatvsllrdGtelvlaslGdsrailcrnGk.....akkltrdhdP
GNPEEVQRILNQHPPEESTTViRFERLLGRLAPLRAFGDARFK
|| .||.. |.... .. |||| |..|| .|
eleeekerikaagGsvewnsl.gkplvngrlamtrslGdldlk
|
|||||||||
| subfamily_PPM1L_pd | Subfamily PPM1L | 383-424 | 4.4e-11 | 35.6 | In-house | 194-236 (269) | alignment | ||
Range on Protein: 383-424
Range on HMM: 194-236/269.0
TAEPEVMSYQLQR-TDKFLVLATDGLWDMLSNEEVVHYVQEHV
|.|......|. .||.||.||||| .|||| |....|..
iadpdiltfdlddhkpeflilasdGlwdtfsneeavrfikerl
|
|||||||||
| subfamily_PPM1H_pd | Subfamily PPM1H | 131-311 | 6.8e-11 | 34.5 | In-house | 61-205 (404) | alignment | ||
Range on Protein: 131-311
Range on HMM: 61-205/404.0
GGYLFGVMDGHGGNACAHNVCKRLPDYIALSLLHRHVLLAHPDLmpkltdyltitknEDHCYNYANDPACRNSLNKYFyeLQDMVEaHVEMHVRSIREAY
..||. |||.|.. | | | . | . ||.. . |.. .... .| .. . . .. . |. . .. .|.
playfglfDGhaGsgaalvaskllhkhlkekledvlellleksa.............eeeenteesskespssvseiy..eekeis.keeLviGalesaf
IRLDQDIRNEAVKeskSKlpegsschafdaANAGACALVAYIQGTELFLANAGDCRAVLGVQGEDgcwsaMQLSSDHTAGN
...|. |..| . . . | .|||| . |..|||||.||.| ..| ..||.|.|
lemDeqiarerea...yr............ikGGCtalvalvllgklYvanaGDsRailvrkdei.....iplsadftPet
|
|||||||||
| subfamily_ILKAP_pd | Subfamily ILKAP | 382-431 | 2.4e-10 | 33.1 | In-house | 201-250 (293) | alignment | ||
Range on Protein: 382-431
Range on HMM: 201-250/293.0
LTAEPEVMSYQLQRTDKFLVLATDGLWDMLSNEEVVHYVQEHVCKKVEDT
... |.|. .|. |.|.||| ||||. .|..|||..... . .. .|.
vistPdvkkceLtendlfvvlaCdGLwkvfsadevvkfilkvledeeddr
|
|||||||||
| subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 376-422 | 3.4e-10 | 32.6 | In-house | 175-222 (255) | alignment | ||
Range on Protein: 376-422
Range on HMM: 175-222/255.0
FYTPPYLTAEPEVM-SYQLQRTDKFLVLATDGLWDMLSNEEVVHYVQE
. |.....|.. |.. ...||||.|| ||.||..|.|| |. | .
sflePfvvpdPdlsqsleiskkdkflilacdGiwdlisdeeaveivag
|
|||||||||
| PPM_PTC7_motif | 401-427 | 3.5e-10 | 33.2 | In-house | 1-27 (51) | alignment | |||
Range on Protein: 401-427
Range on HMM: 1-27/51.0
VLATDGLWDMLSNEEVVHYVQEHVCKK
.||.|||||.||..|.|. |.....||
iLAsDGLWDvlsdqeavdlvrdqlskk
|
|||||||||
| subfamily_PP2D1_pd | Subfamily PP2D1 | 384-438 | 9e-10 | 30.8 | In-house | 266-320 (492) | alignment | ||
Range on Protein: 384-438
Range on HMM: 266-320/492.0
AEPEVMSYQLQRTDKFLVLATDGLWDMLSNEEVVHYVQEHVCKKVEDTSKGVLPQ
||.. | .|. ...|||||. |||..||.|||. |.. . . . ....|.
pePkttsvkldeaaqflvlAsnGlWevlseeevlsLvkqtlaiyksrvraenvpd
|
|||||||||
| subfamily_PPM1D_pd | Subfamily PPM1D | 384-463 | 1.7e-09 | 30.2 | In-house | 224-287 (309) | alignment | ||
Range on Protein: 384-463
Range on HMM: 224-287/309.0
AEPEVMSYQLQRT-DKFLVLATDGLWDMLSNEEVVHYVQEHVCKKVEDTSKGvlpqditfneqelpcdlNNAASCLVREAL
||.|. ..|. .||..||.||||..|. |..|. |... .||. ... .. |..||.|||
PePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqs.................rsvakalvkeal
|
|||||||||
| subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 261-349 | 7.2e-09 | 28.3 | In-house | 93-175 (255) | alignment | ||
Range on Protein: 261-349
Range on HMM: 93-175/255.0
ANAGACALVAYIQGTELFLANAGDCRAVLGVQgeDGcwSAMQLSSDHTAGNPEEVQRILNQHPPEESTtvIRFERLLGRLAPLRAFGDA
|. | ...| . ..|| || |.||. . || | .|| || ...| .|| . || |. | || ||.||.
kfiGttaasvliiedkvyianvGdsrvvlcqk..dg..takrlsldhkPseeseekriselGGtvvst..vvtsrvnGtlavsralGds
|
|||||||||
| subfamily_ILKAP_pd | Subfamily ILKAP | 264-352 | 1.1e-08 | 27.6 | In-house | 114-197 (293) | alignment | ||
Range on Protein: 264-352
Range on HMM: 114-197/293.0
GACALVAYIQGTELFLANAGDCRAVLGVQGEDGC-WSAMQLSSDHTAGNPEEVQRIlnqhppEESTTVIRFERLLGRLAPLRAFGDARFK
|. | | . |. || || .||| . |.| ....|. |||. . || .|| . . .|.| |.|| | |. || |||
GstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkri......qkaGgvvrdgrvlGvlevsrsiGdgrfk
|
|||||||||
| PP2C_SIG_SM00331 | 211-495 | 1.5e-08 | 27.5 | In-house | 52-216 (217) | alignment | |||
Range on Protein: 211-495
Range on HMM: 52-216/217.0
LQDMVEAHVEMHvRSIREAYIRLDQDIRNEavkesksklpegsscHAFDAANAGACALVAYIQGTELFLANAGDCRAVLGVqgEDGCWSAMQLssdhtag
|..... ... . .. .| ||.. |..| . .. | ..... ... .| .|||||.| .| ... .
lrtalrellseg.eelsqalkrlnraiyee...............keekgmfaTlllalydfssgklsyanaGdsrpyllr..dgklveilkd.......
npeevqrilnqhppeesttvirferllgrlaplrafgdarfkwdkktqnkvysksslnpmseV-----------EhfytppyltaePEVMSYQLQRtDKF
| . ... . .|. . .
..............................................................vegaplGlepevs...........vdirelelek.gdl
LVLATDGLWDMLSNE-----EVVHYVQEHVCKKVEDTSKGVLPQDITFNEQELPcdlnnaasclvrealggddhvavsttlsipypdvrmyRDDISVIVV
|.|.||||... | . .. . ....|. ... .. . . ... ... .|||.|.||
lllytDGltearsekgfaeerleeiledlvdseaqelaqkiveellelakgsng.....................................eDdiTvvvv
F
.
k
|
|||||||||
| subfamily_Choan-PPM1K-like_pd | Subfamily Choan-PPM1K-like | 214-320 | 8.2e-08 | 25.1 | In-house | 40-143 (292) | alignment | ||
Range on Protein: 214-320
Range on HMM: 40-143/292.0
MVEAHVEMHVRSIREAYIRLDQDIRNEAVkESKSKLPEGSSCHAFDAANAGACALVAyiQGTELFLANAGDCRAVLGVQGEDGCWSAMQLSSDHTAGNPE
. | ..|... . | . . . . . .|| . . |. | || | . .|.||| || ||.|| . || || .|.
laedtlevelleltrqlqelsealllril.diaakldkltidaresattavvcarvr..ddralilanvGdsrallgrclggsdyeliPlsrdhkPedPd
EVQRILN
| .|||.
erarilr
|
|||||||||
| subfamily_PHLPP_pd | Subfamily PHLPP | 372-422 | 2.3e-07 | 23.0 | In-house | 164-214 (246) | alignment | ||
Range on Protein: 372-422
Range on HMM: 164-214/246.0
EVEHFYTPPYLTAEPEVMSYQLQRTDKFLVLATDGLWDMLSNEEVVHYVQE
. .... |.. .|.| . .|. | .|.. . ||..|| .|.|. |..
llGytflfPvvlPkphvrevlLteqdellivGnkalWevlsideaveavrk
|
|||||||||
| PP2C_2 | Protein phosphatase 2C | 228-431 | 3.2e-07 | 22.8 | Pfam-A | 82-201 (212) | alignment | ||
Range on Protein: 228-431
Range on HMM: 82-201/212.0
EayirldqdirneavkesksKLPEGSSCHAfDAANAGACALVAYIQGTELFLANAGDCRAVlgVQGEDGCWSAmqLSSDHTAGNPEEVQRILNQHPPEES
. . | .. .. .. . .. |.| |...|..... ||...| |...|| . . |..... . |.... . . ||
k...................lkqeaeaqqe.elkdyatTlllavitpgeivffqiGDgaiv..vrdrdgevql..lgepdsgeyanettfltsedaeeel
ttvirferllgrlaplrafgdarfkwdkktqnkvysksslnpmsevehfytppyltaepEVMSYQlQRTDKFLVLATDGLWDMLSNEEVVHYVQEHVCKK
.. . . . . |.| |||..|.|..|| .. . ......
...........................................................rirrlk.lepgdalllmTDGvsdslrkeepfrellaellet
VEDT
.|..
leee
|
|||||||||
| PP2C_2 | Protein phosphatase 2C | 228-431 | 3.2e-07 | 22.8 | In-house | 82-201 (212) | alignment | ||
Range on Protein: 228-431
Range on HMM: 82-201/212.0
EayirldqdirneavkesksKLPEGSSCHAfDAANAGACALVAYIQGTELFLANAGDCRAVlgVQGEDGCWSAmqLSSDHTAGNPEEVQRILNQHPPEES
. . | .. .. .. . .. |.| |...|..... ||...| |...|| . . |..... . |.... . . ||
k...................lkqeaeaqqe.elkdyatTlllavitpgeivffqiGDgaiv..vrdrdgevql..lgepdsgeyanettfltsedaeeel
ttvirferllgrlaplrafgdarfkwdkktqnkvysksslnpmsevehfytppyltaepEVMSYQlQRTDKFLVLATDGLWDMLSNEEVVHYVQEHVCKK
.. . . . . |.| |||..|.|..|| .. . ......
...........................................................rirrlk.lepgdalllmTDGvsdslrkeepfrellaellet
VEDT
.|..
leee
|
|||||||||
| subfamily_Choan-PPM1K-like_pd | Subfamily Choan-PPM1K-like | 387-422 | 4.3e-07 | 22.7 | In-house | 237-272 (292) | alignment | ||
Range on Protein: 387-422
Range on HMM: 237-272/292.0
EVMSYQLQRTDKFLVLATDGLWDMLSNEEVVHYVQE
.. .|.. |.|||||.||. |.|.|.||| ....
rklekeldsddaflvlasdGvldvllnaevvlllak
|
|||||||||
| subfamily_Dicty-PPM1L-like_pd | Subfamily Dicty-PPM1L-like | 395-427 | 2.6e-06 | 19.5 | In-house | 234-266 (305) | alignment | ||
Range on Protein: 395-427
Range on HMM: 234-266/305.0
RTDKFLVLATDGLWDMLSNEEVVHYVQEHVCKK
|.||||||||||..||...|| |.| . .|
anDqflvlatdGlwevlsyqdvveevkellrdk
|
|||||||||
| subfamily_PPM1K_pd | Subfamily PPM1K | 383-443 | 2.7e-06 | 19.7 | In-house | 187-246 (263) | alignment | ||
Range on Protein: 383-443
Range on HMM: 187-246/263.0
TAEPEVMSYQL-QRTDKFLVLATDGLWDMLSNEEVVHYVQehVCKKVEDTSKGVLPQDITFN
|.|| | .. .| |||| |||. ......|. ..|. .|.. |.... . | . .
iatPetkslkvdhaadsflvlitdgisfvvnsqelcdlvr..lchdpeeaahalteqalqyg
|
|||||||||
| subfamily_PPTC7_pd | Subfamily PPTC7 | 387-432 | 4.2e-06 | 19.3 | In-house | 158-202 (252) | alignment | ||
Range on Protein: 387-432
Range on HMM: 158-202/252.0
EVMSYQLQRTDkFLVLATDGLWDMLSNEEVVHYVQEHVCKKVEDTS
...|..... | .|||||||.| |...|... ..| ... ..
dsksfavkkgD.iivlatDGlfDNlledeileilkelkeseksslq
|
|||||||||
| subfamily_PP2D1_pd | Subfamily PP2D1 | 271-320 | 9.6e-06 | 17.5 | In-house | 184-228 (492) | alignment | ||
Range on Protein: 271-320
Range on HMM: 184-228/492.0
YIQGTELFLANAGDCRAVLGVQGedgcwSAMQLSSDHTAGNPEEVQRILN
.. . |..||||. .||| .| .|..| .|| .|..| .|. .
leelgvlyianaGnvqAvLcreG.....kaiiLtreHtprnkkERtRvek
|
|||||||||