Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PDP_pd | Subfamily PDP | 121-499 | 1.8e-146 | 481.3 | In-house | 1-398 (398) | alignment | ||
Range on Protein: 121-499
Range on HMM: 1-398/398.0
DSNILPSNEPTEDRNAECEMLSSNGTLFSVIDGHGGYHCAEAVKKRLPLYVALALLKETDLTQFEKEIVEDLLISRFSDKSGPKTSVANDSSSDNDLSKK
|||.|.||||.|||..|...|.|||.||.|.|||||..|||||.|||. |||..|||...|...||.. .. ......|| |..|..|......||..
dsnqLasNePiEDrrseakllesngvlfgvfDGHggaacaeavskrLlkyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslsel
QdvfhtgpKYMVQALQARLEngcrlSMDEALSFAFTHLDDDIVTEAI---PVKVLDDSFLAGASGACTIAAYIEGDQLLVANAGDCRAVLGSVNGDGSWV
. ||. ..|.|..| ...|||. ||..||.||.|||. . |.|....|...||||...|.|||..| |||.||||||||.....|||
s.......kylqelleaeve.....kvkealkkaFlklDkdistealkklkekslreallvalsGacallaliegtelhvAntGDcravlgvqeeegswe
ATPLSADQTANSREEFQRVWSQHPGEEA-TVIKNGRLLGQLQPLRAFGDIQYKWDRVTHNHILTQVYgGPIVPPHVYKSPPYLTAEPVVTKRQLRSKDRF
|..||.||||...||..|....|||||. |||.||||||.|||||||||..|||.. .....|...| ....|. ||.||||||||.||...||..|.|
avkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwseelqkkvlekay.lkvlepkdyktPPYltaePevtshklrendkF
LILATDGLWDSMSSDKAVELVGQFVNGAGRKSDV-------------------------LEHNAASHLIRHAIGGN---DHHFVAQMLLVPDQYRRMWRD
|.||||||||..|....|.|||...... .|..| ...|||.||||||.||| |.. |...| .|....||.||
LvlatDGLwdllsneevvslVgehlakkkekepvkveeakltlkqvveelkerkrklkredknaAthLirhalggneagdkekvsallsiPeelaRmyRD
DITVTVVFFNS
|||||||||||
DitvtVvffns
|
|||||||||
PP2Cc_SM00332 | 123-495 | 6.9e-55 | 179.4 | In-house | 16-274 (274) | alignment | |||
Range on Protein: 123-495
Range on HMM: 16-274/274.0
NILPSNEPTEDRNAECEML--SSNGTLFSVIDGHGGYHCAEAVKKRLPLYVALALLKETDLTqfekeivedllisrfsdksgpktsvandsssdndlskk
. ..... ||. . | ......|.| ||||| .|. |.|.|| ... | |..|
smqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel......................................
qdvfhtgpkymvqalqarlengcRLSMDEALSFAFTHLDDDIVTEAIPVKVLDdsflaGASGACTIAAYIEGDQLLVANAGDCRAVLGSVNGdgswvATP
.. |||. || .|..|..|. . . ||.. . |.. ...| |||.||.||||.. . |..
.......................eddveealkkaflstdeeileeeqskelen.....alsGstavvallkkedlyvanvGDSravlcrngk.....avq
LSADQTANSREEFQRVWSQHPgeeatVIKNGRLLGQLQPLRAFGDIQYKWDRvthnhiltqvyggpivpphvYKSPPYLTAEPVVTKRQLRSKDRFLILA
|| |.... .| .|. .... |...||. |.|. ||||| ..|. . .. .||.|||| |. .|.|.|.|||||
lsvdhkpedederkRikkagg.....vvekgrvngglavsrafGdhflkknk....................klkepyitaepdvkvvtltsedeflila
TDGLWDSMSSDKAVELVGQFVNGAgrkSDVLEHNAASHLIRHAIGGndhhfvaqmllvpdqyrRMWRDDITVTVV
.|||||..|....|..| .. . .. ..|| .|...|| .. .|.||| ||
SDGlwdvlsnqevvdivrkllakg...ktndpqeaaelldeeairr.................ggseDniTvvvv
|
|||||||||
0034914 | PP2C-like | 121-498 | 1.1e-50 | 165.2 | In-house | 25-291 (295) | alignment | ||
Range on Protein: 121-498
Range on HMM: 25-291/295.0
DSNILPSNEPTEDRNAECEM---LSSNGTLFSVIDGHGGYHCAEAVKKRLPLYVALALLKETDLTQFEkeivedllisrfsdksgpktsvandsssdndl
. . ... ||. . | ....|| | |||||...|| ....|. ... .| | . |....
vasdqGrrksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltls................................
skkqdvfhtgpkymvqalqarlengcRLSMDEALSFAFTHLDDDIVTEAIPvkvlddSFLAGASGACTIAAYIEGDQLLVANAGDCRAVLGsvN-Gdgsw
.. ||| || ..| .....|. . ||.. ..|.| |..| |||.||.|||| . |
..........................ledieealrkaflaadeellelall......rpelagsGtTavvalirgnklyvanvGDSravll..rng....
VATPLSADQTANSREEFQRVWSQHPgeeatVIKNGRLLGQLQPLRAFGDIQYKWDrvthnhiltqvyggpivpPHVYKSPPYLTAEPVVTKRQLR-SKDR
....|. |.. ....|..|..| .. .. .||..|.|. ||.|| ..|. .... ..|...||| || ..| ..|
elvqltvdhkpvnelererilsagg.....avshgrvngvlavtRalGdfdlkll..................lslllleplvsaePdvtvleltleddd
FLILATDGLWDSMSSDKAVELVGQFVNGAGRksdvlEHNAASHLIRHAIGgndhhfvaqmllvpdqyrRMWRDDITVTVVFFN
||.||.||||| .|.. .|..| ..... ..|| .|...|. |. ||.||| ||..|
fllLasDGlwdvlsneeivdivrsllakgld.....leeaaeeLvdlAla..................rgsrDNiTvvvvrln
|
|||||||||
PP2C | Protein phosphatase 2C | 275-463 | 1.2e-36 | 119.6 | Pfam-A | 95-246 (255) | alignment | ||
Range on Protein: 275-463
Range on HMM: 95-246/255.0
SfLAGASGACTIAAYIEGDQLLVANAGDCRAVLGSVNGDGswvaTPLSADQTANSREEFQRVWSQHPGEEAtvikNGRLLGQLQPLRAFGDIQYKWDRvt
. . ||.. . |.| |..| |||.||.||||.. ... . |. |.......| .|. ... . |||. |.|. ||.|| ..| .
t.epsksGstavvalirgkklyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn....ngrvngsLavsRalGdfelkpke..
hnhiltqvyggpivpphvyksPPYLTAEPVVTKRQLRSKDRFLILATDGLWDSMSSDKAVELVGQFVNGAGrksdvLEHNAASHLIRHA
... .||| ||...| ..| |||||.||||| .|...||.|| .... . .|| |...|
.....................eqlvsaePdvtsvklteedefliLasdGlwdvlsdqeavdlvrselskkk.....spmeaaeelvdea
|
|||||||||
PP2C | Protein phosphatase 2C | 275-463 | 1.2e-36 | 119.6 | In-house | 95-246 (255) | alignment | ||
Range on Protein: 275-463
Range on HMM: 95-246/255.0
SfLAGASGACTIAAYIEGDQLLVANAGDCRAVLGSVNGDGswvaTPLSADQTANSREEFQRVWSQHPGEEAtvikNGRLLGQLQPLRAFGDIQYKWDRvt
. . ||.. . |.| |..| |||.||.||||.. ... . |. |.......| .|. ... . |||. |.|. ||.|| ..| .
t.epsksGstavvalirgkklyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn....ngrvngsLavsRalGdfelkpke..
hnhiltqvyggpivpphvyksPPYLTAEPVVTKRQLRSKDRFLILATDGLWDSMSSDKAVELVGQFVNGAGrksdvLEHNAASHLIRHA
... .||| ||...| ..| |||||.||||| .|...||.|| .... . .|| |...|
.....................eqlvsaePdvtsvklteedefliLasdGlwdvlsdqeavdlvrselskkk.....spmeaaeelvdea
|
|||||||||
PPM_PTC7 | 277-451 | 2.5e-35 | 115.1 | In-house | 97-238 (259) | alignment | |||
Range on Protein: 277-451
Range on HMM: 97-238/259.0
LAGASGACTIAAYIEGDQLLVANAGDCRAVLGSVNGDGswvaTPLSADQTANSREEFQRVWSQHPGEEATviKNGRLLGQLQPLRAFGDIQYKWDRVthn
. ||.. . |.| |..| |||.||.||||.. ... ..|. |.......| .|. . . . .|||. |.|. ||||| ..| . .
epstsGstAvvalitgsklyvAnvGDSravLcrsgnav....kqltedHkpsnedEreRiegaggsvsnv..gngrvngvlavsRafGdfelkpket...
hiltqvyggpivpphvykSPPYLTAEPVVTKRQLRSKDRFLILATDGLWDSMSSDKAVELVGQFVNGAgrksdvL
......||| ...... ..| |||||.||||| .|...||.|| ....
..................eeqlvsaePdisstkideedefliLasdGlwdvvsdqeavdlvrselskk......d
|
|||||||||
0049733 | PP2C-like | 130-498 | 4.1e-33 | 107.7 | In-house | 17-234 (235) | alignment | ||
Range on Protein: 130-498
Range on HMM: 17-234/235.0
PTEDRNAEcemlssNGTLFSVIDGHGGYHCAEAVKKRLPLYVALALLKETDLTqfekeivedllisrfsdksgpktsvandsssdndlskkqdvfhtgpk
||. . ...|| | |||||....| . ..|. ... .||. . |.
vneDavlv......glllfavaDGhgghaagevasellvetllelllelllld...............................................
ymvqalqarlengcrlsMDEALSFAFTHLDDDIVTEAIPVKvlddsfLAGASGACTIAAYIEGDQLLVANAGDCRAVLGSvngDGswVATPLSADQTANS
. ||| ||..... .. .|. . .|.. ..|.. |..| |||.||.||.| . || ...|. |.. .
.................leealrkaflaaneallelalasp......elagmgtTavvalldggklyvanvGDsrayllr...dg..klvqltedhspvn
REEFQRVWSQHPGEeatvikngRLLGQLQPLRAFGDIQYKwdrvthnhiltqvyggpivpphvyksppyltaePVVTKRQLRSKDrFLILATDGLWDSMS
..|.||... .. | .|.|. .||.|| ..| | || .|.. | ||.||.||||| .|
elerqriitaggav........rvpgrlaltralGdlllk.................................pdvtvlelepgd.flllasDGlwdvls
SDKAVELVGQfvNGAgrksdvleHNAASHLIRHAIGgndhhfvaqmllvpdqyrRMWRDDITVTVVFFN
.. .|.|. . . . ..||..|...|. | ||.||| ||...
deeivdllrs..ldl........eeaaerlvelala..................rggrDNiTvvvvrld
|
|||||||||
subfamily_PPM1G2_pd | Subfamily PPM1G2 | 144-443 | 7.5e-26 | 83.7 | In-house | 51-249 (287) | alignment | ||
Range on Protein: 144-443
Range on HMM: 51-249/287.0
NGTLFSVIDGHGGYHCAEAVKKRLPLYVALallketdltqfekeivedllisrfsdksgpktsvandsssdndlskkqdvfhtgpkymvqalQARLEngc
. .||.| ||||| ..|. . |.| ..| . ..
slalfavfDGhGGakvakyagkklikkiak..............................................................kksfk...
RLSMDEALSFAFTHLDDDIVTEaipvKVLDDSflagASGACTIAAYIEGDQLLVANAGDCRAVLGSvNGDgswvATPLSADQTANSREEFQRVWSQhpge
. .....| || ..| ... . . |.|. .|. .... |. ..|.|||||| |||| | .|. . || | .. .| .|. .
egaleqilkdafletDeellkd....eklkde....saGstavvvlikeeklyvanaGDsravlss.kgn....vkalsfDhkPqeesekkriiaa....
eATVIKNGRLLGQLQPLRAFGDIQYKWDRVthnhiltqvyggpivpphVYKSPPYLTAEPVVTKRQLRSKDRFLILATDGLWDSMSSDKAVELVGQFVNG
... .| |.| ||.|| ..| . ||.| |. ..|...| ||.|| ||.|| ..... |.|| . .
.gGfvelnrvngnLalsralgDfefkknvk..................kkpeeqivtavPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvs
|
|||||||||
subfamily_PPM1G_pd | Subfamily PPM1G | 280-440 | 9.3e-21 | 67.3 | In-house | 295-428 (473) | alignment | ||
Range on Protein: 280-440
Range on HMM: 295-428/473.0
ASGACTIAAYIEGDQLLVANAGDCRAVLGSVngdgsWVATPLSADQTANSREEFQRVwsQHPGEeaTVIKNGRLLGQLQPLRAFGDIQYKWDRVTHNHil
||. . | .....|.||||||.|.|| . .| || | . .| .|. .. | .| ..||. | | ||.|| || .. ..
dsGttAvvaLlkekklivAnaGDsRcvlsrn.....GkAldlslDHkPeDevEleRi..ekAGG..kvdedgRvnGGLnlsRAlGDhaYkkneeLplk..
TQVyggpivpphvyksppyLTAEPVVTKRQLRSKDRFLILATDGLWDSMSSDKAVELVGQF
|. ..| | . ...| ..| ||.||.||.|..|.|.. |. | .
eqm................isAlPDikvltlteedeFlvlAcDGiWnvmesqevvdfvrak
|
|||||||||
PPM_PTC7_SpoIIE | 246-443 | 8.8e-18 | 57.9 | In-house | 68-211 (230) | alignment | |||
Range on Protein: 246-443
Range on HMM: 68-211/230.0
SMDEALSFAFTHLDDDIVTEaipvkvlddsflAGASGACTIAAYIEGDQ--LLVANAGDCRAVLGSVNGDgswvatplsadqtansreefqrVWSQHpGE
.|.|. .. |..|. .| . |||. . |.|.... | ||||||....| . .| .. . ..
kpeeilrrlnlalaadlede............psssgaTavvalidpstgklyvanaGdsppllvrddgg......................ereri.va
EATV---IKNGRLLGQLQPLRAFGDIQYKWdrvthnhiltqvyggpivpphvykSPPYLTAEPVVTKRQLRSKDRFLILATDGLWDSMSSDKAVELVGQF
. | .|| |.|. .|.||. .. . . .||| | .||.|||||.||||| .|.. .|.|| .
gglpslGilpgrvfgvlavslapGdlllly........................tDGvveaepdtsdgelfgkdeflilasdglwdvlspqelvdlvrde
VNG
..
lek
|
|||||||||
subfamily_PPM1A_pd | Subfamily PPM1A | 132-372 | 1.5e-17 | 56.8 | In-house | 27-196 (282) | alignment | ||
Range on Protein: 132-372
Range on HMM: 27-196/282.0
EDRNAECEMLS--SNGTLFSVIDGHGGYHCAEAVKKRLPLYVAL-ALLKETDLTQFEKEIVEDLLISRFSDKSGPKTSVANDSSSDnDLSkkqdvfhtgp
||. . |. .....|.|.|||.| ..|. ||| |. . |||. |.. ||. |.. | . | . . . .|... | |
EDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenileeeelkeaaleasekdevkealrqgfLaldeairelstdlkta.dks..........
kymvqalqarlengcrlsmdealsfafthldddivteaipvkvlddsflagasGACTIAAYIEGDQLLVANAGDCRAVLGSvNGdgswVATPLSADQTAN
|. .... .. ..|..||.||.|||| . || |. |. | ..
.....................................................GsTavtvlvsekhliianlGDsRavlcr.ng....kaaflteDHkps
SREEFQRVwsQHPGEeaTVIkNGRLLGQLQPLRAFGDIQYKWDR
. .| .|. .. | .|. ..|. |.| ||.|| .|| .
rpkEkkRi..eqAGG..svv.vsRvnGaLAvsRalGDyeykeee
|
|||||||||
subfamily_PPM1L_pd | Subfamily PPM1L | 144-369 | 1.9e-11 | 36.7 | In-house | 34-188 (269) | alignment | ||
Range on Protein: 144-369
Range on HMM: 34-188/269.0
NGTLFSVIDGHGGYHCAEAVKKRLPLYVALALLKEtdltqfekE-------Ivedllisrfsdksgpktsvandsssdndlskkqdvfhtgpkymvqalq
. ..|.| ||||| || .|..|. . |.. .
gesffavfdGhGGefaaefakdvlvkaiknkliel........dadkentep................................................
arlengcrlsmdeaLSFAfTHLDDDIVteAIPVKVLDDSFLA-GASGACTIAAYIEGDQLLVANAGDCRAVLGSVNGdgswVATPLSADQTANSREEFQR
..|. . | |.|. .. |.|. | .|. .. | .....|.||| || | || .| | ||| | . .| .|
..............infs.klltdeil..svdekllekakraediaGttalialvqesdlivanvGdsrGvlydkrG....kaiplsfdhkpqqvkerkr
VwsQHPGEEATVIKNGRLLGQLQPLRAFGDIQYK
. .. | . |. | | ||.|| |
i..kkaGGfiafrGvwrvaGvlatsralGdyplk
|
|||||||||
subfamily_PPM1H_pd | Subfamily PPM1H | 397-495 | 1.9e-10 | 33.1 | In-house | 303-400 (404) | alignment | ||
Range on Protein: 397-495
Range on HMM: 303-400/404.0
PYLTAEPVVTKRQLR----SKDRFLILATDGLWDSMSSDKAVELVGQFVNGAGRKSDVLEHNAASHLIRHAIGGNDHHFvaqmlLVPDQYRRMWRDDITV
|.|...| |. ..|. ..| |||||||||| .| ... |.| .... .. . ..| .|. .| | ... . .. . |||.|
PfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvepedkkrytavaqeLvaaarGklkdkg.....WrlkeekaasvDDisv
TVV
|.
fvi
|
|||||||||
subfamily_PPM1A_pd | Subfamily PPM1A | 399-498 | 2.6e-10 | 33.1 | In-house | 205-281 (282) | alignment | ||
Range on Protein: 399-498
Range on HMM: 205-281/282.0
LTAEPVVTKRQLRSKDRFLILATDGLWDSMSSDKAVELVGQFVNGAGRKSDVlehnaashlirhaiggndhhfvaQMLLVPDQYRRMWRDDITVTVVFFN
..||| || . ..| ||.|| ||.|| .|....|||| . .. | . | || ... || ..| ||.|.
vsaepevtsierseeddflvlacDGiwDvlsdeevvelvrkrlevadeleev.......................akalvdkalekgsrDNlsvlvvlfa
|
|||||||||
subfamily_TAB1_pd | Subfamily TAB1 | 281-392 | 3e-10 | 32.4 | In-house | 129-236 (333) | alignment | ||
Range on Protein: 281-392
Range on HMM: 129-236/333.0
SGACTIAAYIEGDQLLVANAGDCRAVLGSVNGdgSWVATPLSADQTANSREEFQRVwsQHPGEEATVIKNGRLLGQLQPLRAFGDIQYKWdRVTHNHILT
|. . | | ..| |||.|| ||.| . | . || | | . .|..|. .. | .. ||. ..||. .. |. || . | . . ||.
gGttAvvalifnnkLyVaNvGdsrAllvkrke..sekvkqLsvdHttdNedEllRl..kdLGldieqikrnkrlgskentRsiGdykvkk.gykdvdils
QVYGGPIVP-PHV
. | |.. |..
sakgePviaePdi
|
|||||||||
subfamily_PPM1E_pd | Subfamily PPM1E | 395-464 | 3.6e-10 | 32.5 | In-house | 182-247 (265) | alignment | ||
Range on Protein: 395-464
Range on HMM: 182-247/265.0
SPPYLTAEPVVTKRQLRSKDRFLILATDGLWDSMSSDKAVELVGQFVNGAGRKSDvlehNAASHLIRHAI
. ||...|. |.. .| ... .||||.||||| . ...|.|| .|.. ... ..| .|. .|.
lkpyvsgeadvaeveldgseeylilacDGlwDvvneeevvklveefladgaedls....evakllveaak
|
|||||||||
subfamily_ILKAP_pd | Subfamily ILKAP | 251-370 | 6.9e-10 | 31.5 | In-house | 89-198 (293) | alignment | ||
Range on Protein: 251-370
Range on HMM: 89-198/293.0
LSFAFTHLDDDIVTEAIPVKvldDSFLAGASGACTIAAyieGDQLLVANAGDCRAVLGSVNGDGS-WVATPLSADQTANSREEFQRVwsQHPGeeaTVIK
| .|.. |.. ...| | .. |. .. .. . | ||| || .||| . .|. .. .|. | |. . || .|. | | .|..
lvdsfkktdeefLklaskak...PvWkdGstatvvlvl...dnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkri..qkaG...gvvr
NGRLLGQLQPLRAFGDIQYKW
.||.|| |. |. || ..|
dgrvlGvlevsrsiGdgrfkr
|
|||||||||
subfamily_ILKAP_pd | Subfamily ILKAP | 399-458 | 7.1e-10 | 31.5 | In-house | 201-260 (293) | alignment | ||
Range on Protein: 399-458
Range on HMM: 201-260/293.0
LTAEPVVTKRQLRSKDRFLILATDGLWDSMSSDKAVELVGQFVNGAGRKSDVLEHNAASH
... | |.| .| |.|..|| ||||...| |..|. . . .. . ..... |.. |.
vistPdvkkceLtendlfvvlaCdGLwkvfsadevvkfilkvledeeddrkikeeekksk
|
|||||||||
subfamily_PPM1D_pd | Subfamily PPM1D | 142-336 | 1.2e-09 | 30.7 | In-house | 32-164 (309) | alignment | ||
Range on Protein: 142-336
Range on HMM: 32-164/309.0
SSNGTLFSVIDGHGGYHCAEAVKKRLPLYVAlallKETDLTQFEKEIVedllisrfsdksgpktsvandsssdndlskkqdvfhtgpkymvqalqarlen
. . . ..|.||||| . |. ....| .. |...... |.| |
elevafvavfDGHGGkeAakfarehlwsvik....kqkkflssepedv....................................................
gcrlsmDEALSFAFTHLDDDIVTEAIPVKVLDDSFLAgASGACTIAAYIEGDQLLVANAGDCRAVLGSVNG-DGSWVATPLSADQTANSREEFQRV
||.. || .. . . . |. .|. . | ...| ||. || ..|||. . . ...|..| | .| || .|.
......leAireaflatheamkkkleeWpktksglls.taGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekeri
|
|||||||||
PP2C_SIG_SM00331 | 279-496 | 1.8e-09 | 30.5 | In-house | 85-216 (217) | alignment | |||
Range on Protein: 279-496
Range on HMM: 85-216/217.0
GASGACTIAAY-IEGDQLLVANAGDCRAVLGSvnG--DGSWVATplsadqtansreefqrvwsqhpgeeatviKNGRLLGQLQPLRafgdiqykwdrvth
| ....| | .....| .|||||.| .| .. ..|..|| . ..
gmfaTlllalydfssgklsyanaGdsrpyllr..dgklveilkd.............................vegaplGlepevs..............
nhiltqvyggpivpphvyksppyltaePVVTKRQLRSKDrFLILATDGLWDSMSS-----DKAVELVGQFVngaGRKSDVLEHNAASHLIRHAIGGNDhh
. .....| .| .|.|.||||.. .|. .. |.. ..| . .. | .. |...| | |
...........................vdirelelekgd.llllytDGltearsekgfaeerleeiledlv...dseaqelaqkiveellelakgsng..
fvaqmllvpdqyrrmwRDDITVTVVF
.||||| ||.
................eDdiTvvvvk
|
|||||||||
subfamily_PPM1H_pd | Subfamily PPM1H | 140-341 | 2.2e-09 | 29.6 | In-house | 57-218 (404) | alignment | ||
Range on Protein: 140-341
Range on HMM: 57-218/404.0
MLSSNGTLFSVIDGHGGYHCAEAVKKRLPLYVALALLKETDLTQFEKEivedllisrfsdksgpktsvanD--------SssdndlskKQDVFHTGPKYm
. . ..|.. |||.|. | . | | . | . ..| . ... . | |.. .. ..|
eeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellleksa......................eeeenteess........kespssvseiy.
vqaLQARLENGCrLsMDEALSFAFTHLDDDIVTEAIPVKVlddsflAGasGACTIAAYIEGDQLLVANAGDCRAVLGSVNGDgswvaTPLSADQTANS-R
. .... . | . || ||...|. | | .. .| | ... | . ..| ||||||.||.| . .||||| | .. |
...eekeiskee.L.viGalesaflemDeqiarereayri......kG..GCtalvalvllgklYvanaGDsRailvrkdei.....iplsadftPeteR
EEFQRVWSQHP
. .|.. ...|
qRlqelaflkP
|
|||||||||
subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 397-439 | 6.7e-09 | 28.4 | In-house | 179-222 (255) | alignment | ||
Range on Protein: 397-439
Range on HMM: 179-222/255.0
PYLTAEPVVT-KRQLRSKDRFLILATDGLWDSMSSDKAVELVGQ
|.....| .. . . ||.||||| ||.|| .| ..|||.| .
PfvvpdPdlsqsleiskkdkflilacdGiwdlisdeeaveivag
|
|||||||||
subfamily_PPM1K_pd | Subfamily PPM1K | 246-370 | 1.6e-08 | 27.0 | In-house | 66-183 (263) | alignment | ||
Range on Protein: 246-370
Range on HMM: 66-183/263.0
SMDEALSFAFTHLDDDIvTEAIPVKVLDDSFLAGASGAcTIAAYIEGDQLLVANAGDCRAVLGSvNGDgswvATPLSADQTANSREEFQRVWSQHPGEEA
... | || .||... . . .| . . |. . | |.. .| .| .|. || ||.| ||. |. |. | . . .|| .|. . |
dleivlknafeeldkkl.krylefsvaeaellssGtta.tvsllrdGtelvlaslGdsrailcr.nGk....akkltrdhdPeleeekerikaagGsvew
TVIKNGRLLGQLQPLRAFGDIQYKW
. . . .. |.| |..||.. |
nslgkplvngrlamtrslGdldlkr
|
|||||||||
subfamily_PPM1D_pd | Subfamily PPM1D | 402-469 | 1.7e-08 | 27.0 | In-house | 225-292 (309) | alignment | ||
Range on Protein: 402-469
Range on HMM: 225-292/309.0
EPVVTKRQLRS-KDRFLILATDGLWDSMSSDKAVELVGQFVNGAGRKSDvLEHNAASHLIRHAIGGNDH
|| |..|.| ...|.|||.||||. .....||..| . . |.. ... |. |...|.. .
ePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkee.qsrsvakalvkealqrwrs
|
|||||||||
PPM_PTC7_motif | 418-442 | 1.6e-07 | 24.7 | In-house | 1-25 (51) | alignment | |||
Range on Protein: 418-442
Range on HMM: 1-25/51.0
ILATDGLWDSMSSDKAVELVGQFVN
|||.||||| .|...||.|| ....
iLAsDGLWDvlsdqeavdlvrdqls
|
|||||||||
subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 281-367 | 2e-07 | 23.6 | In-house | 95-176 (255) | alignment | ||
Range on Protein: 281-367
Range on HMM: 95-176/255.0
SGACTIAAYIEGDQLLVANAGDCRAVLGSVNGdgswVATPLSADQTANSREEFQRVwSQHPGEEATVIKNGRLLGQLQPLRAFGDIQ
|. .....| .|. .|| || |.||. .| .|. || | . .| .|. |. | . . |. |.| ||.||.
iGttaasvliiedkvyianvGdsrvvlcqkdg....takrlsldhkPseeseekri.selGGtvvstvvtsrvnGtlavsralGdsf
|
|||||||||
subfamily_Dicty-PPM-1_pd | Subfamily Dicty-PPM-1 | 399-443 | 4.1e-07 | 22.1 | In-house | 199-244 (276) | alignment | ||
Range on Protein: 399-443
Range on HMM: 199-244/276.0
LTAEPVVTKR-QLRSKDRFLILATDGLWDSMSSDKAVELVGQFVNG
|..|| |..| | .|.|||.|.||||| .| ..|.| | . .
lisepyvsnrilltpfdkflivasdGlwdvisGkdaiekvkslydq
|
|||||||||
subfamily_KAPP-like_pd | Subfamily KAPP-like | 399-443 | 4.2e-07 | 22.3 | In-house | 189-234 (266) | alignment | ||
Range on Protein: 399-443
Range on HMM: 189-234/266.0
LTAEPVVTKR-QLRSKDRFLILATDGLWDSMSSDKAVELVGQFVNG
|..|| |..| | .|.|||.|.||||| .| ..|.| | . .
lisepyvsnrilltpfdkflivasdGlwdvisGkdaiekvkslydq
|
|||||||||
subfamily_Choan-PPM1K-like_pd | Subfamily Choan-PPM1K-like | 281-337 | 2.1e-06 | 20.5 | In-house | 86-142 (292) | alignment | ||
Range on Protein: 281-337
Range on HMM: 86-142/292.0
SGACTIAAYIEGDQLLVANAGDCRAVLGSVNGDGSWVATPLSADQTANSREEFQRVW
. | . | .. .|..|| || ||.|| . | ||| | . .| .|.
ttavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderaril
|
|||||||||
PPM_PTC7_SpoIIE_motif | 409-495 | 2.5e-06 | 21.1 | In-house | 8-78 (81) | alignment | |||
Range on Protein: 409-495
Range on HMM: 8-78/81.0
QLRSKDRfLILATDGLWDSMSSDKAV----ELVgQFVNGAgRKSDvlEHNAASHLIRHAIGgndhhfvaqmllvpdQYRRMWRDDITVTVV
|| .|. |.|.||||.. ..|| . ||. .... | .. . .| .|..... .... .||||. |.
qLkpgdv.llLyTDGltEardsdgelfgkeell.rladra.egks..lqeladklvdevle...............ngsgereDDitllvl
|
|||||||||
subfamily_PP2D1_pd | Subfamily PP2D1 | 401-442 | 3.2e-06 | 19.1 | In-house | 266-307 (492) | alignment | ||
Range on Protein: 401-442
Range on HMM: 266-307/492.0
AEPVVTKRQLRSKDRFLILATDGLWDSMSSDKAVELVGQFVN
|| .| .| .. ||.||. |||. .| . ..|| |...
pePkttsvkldeaaqflvlAsnGlWevlseeevlsLvkqtla
|
|||||||||
subfamily_PPM1L_pd | Subfamily PPM1L | 412-439 | 3.9e-06 | 19.3 | In-house | 207-234 (269) | alignment | ||
Range on Protein: 412-439
Range on HMM: 207-234/269.0
SKDRFLILATDGLWDSMSSDKAVELVGQ
| .|||||.|||||..| ..||. . .
hkpeflilasdGlwdtfsneeavrfike
|