Gene TAB1 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily TAB1
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP152_AA protein Get Run
NvecP152_AA_33-364 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_TAB1_pd Subfamily TAB1 34-365 4.3e-159 521.7 In-house 3-333 (333) alignment 
Range on Protein: 34-365
Range on HMM: 3-333/333.0
TNQRYRedggrREEHEFEDRSFHFNVDNTC-LYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMTDEEVQLVLRQAFFAVEKGFFQSIDDALAERTELQ
.|.||.     .|.||.||..|.|...|.. ||.||||.||...|.|..|||.|||||.||||.....||. ||..||..||..|..||||||||...||
snrrys.....kedhevedkvflfktendpilyavFdGydGnkaakfveqrLvaellleqltdelaeaevkevlkrafeeverkflesiddalaekddlq

LQIPEGLSSYEAYKQYPRQVERIQELQEHISGGTTAVVALIFNNKLYVANAGDSRALLCKQLEdsSLQVQQLSKDHDTQNEEELLRLARLGLDIVQIQRN
.|.|||.||||...|||...||.|||.|.|||||||||||||||||||||.|||||||.|. |  | .|.|||.||.|.||.|||||..||||| ||.||
sqlPegvssyeleeqypekierlqeleeeisgGttAvvalifnnkLyVaNvGdsrAllvkrke..sekvkqLsvdHttdNedEllRlkdLGldieqikrn

RRIGSQENTRSIGDYCVKGGYKDFDILSHSAEEPVIADPHIVGGFPIDGAFYALVLMSDGVYKCLEEATGTETSNLD-IMCMVATEMQQQTTLNGVAQAV
.|.||.|||||||||.||.||||.||||....|||||.|.|.|..|||...|.||||||||||.|||.||.||||.. |...|.||...|.||..|||||
krlgskentRsiGdykvkkgykdvdilssakgePviaePdiqgaypiddityflvlmSdGvyktLeevtgpetsnvenillevitelekqatlqdvAqav

VDKVGRYHHDKYM----EQFNTCQKRDDMTLLVRVFSE
|||| |.|.|.|.    |....|.|||||||||. |.|
vdkvkrkHkdaylssaseravicrkrddmtllvlkfee
0034914 PP2C-like 34-364 1.8e-46 151.3 In-house 21-291 (295) alignment 
Range on Protein: 34-364
Range on HMM: 21-291/295.0
TNQRYREDGGRreEHEFEDRSFHFN-----VDNTCLYGVFDGHDGASVADFAAQRLPAELLLQ----QLTDDMTDEEVQLVLRQAFFAVEKGFFQSIDDA
..  .  | ||   .. ||. ...       ....|.|||||| | ..|..|...|. .|| .    .|......| .. .||.|| |... ... . . 
lrvgvasdqGr..rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallr

laertelqlqipeglssyeaykqyprqveriqelQEHISGGTTAVVALIFNNKLYVANAGDSRALLCkqlEDSslQVQQLSKDHDTQNEEELLRLARLGL
                                   |.. .|||||||||..|||||||.|||||.|.    .   ...||..||.  ||.|  |. ..| 
..................................pelagsGtTavvalirgnklyvanvGDSravll...rng..elvqltvdhkpvnelererilsagg

DIVQiqrNRRIGSQENTRSIGDYCVKGGYKDfdilsHSAEEPVIADPHIVgGFPID-GAFYALVLMSDGVYKCLEeatgtetsNLDIMCMVATEMQQQTT
 ..    .|. |.   ||..||.. |  ...     .  | .|.| |..   .... .    |.|.|||....|.        | .|. .|.. ......
avsh...grvngvlavtRalGdfdlklllsl.....llleplvsaePdvt.vleltledddfllLasDGlwdvls........neeivdivrsllakgld

LNGVAQAVVDKVGRyhhdkymeqfntCQKRDDMTLLVRVFS
|. .|...|| . .            . .||..| .|  ..
leeaaeeLvdlAla............rgsrDNiTvvvvrln
PP2Cc_SM00332 51-360 1.1e-41 136.1 In-house 25-273 (274) alignment 
Range on Protein: 51-360
Range on HMM: 25-273/274.0
EDRSFHFN----VDNTCLYGVFDGHDGASVADFAAQRLPaELLLQQLTDDMTD--EEVQLVLRQAFFAVEKGFFQSIDDALAERtelqlqipeglssyea
||. .  .     ... ..|||||| |..||.|....|| | | ..|  . ..  ..|. .|..|| .... . .. .  . |.                
eDahvvvvdlveeedwlffgvfDGhgGsevakfvskklp.ealkeelkkkkdeleddveealkkaflstdeeileeeqskelen................

ykqyprqveriqelqehISGGTTAVVALIFNNKLYVANAGDSRALLCKQLEdsslqVQQLSKDHDTQNEEELLRLARLGLdivQIQRNRRIGSQENTRSI
                  . |.||||||. ...|||||.||||| ||.. .     . |||.|| ...|.|. |. . |    .....|  |... .|..
.................alsGstavvallkkedlyvanvGDSravlcrngk.....avqlsvdhkpedederkRikkagg...vvekgrvngglavsraf

GDYCVKGGYkdfdilsHSAEEPVIADPHIVGgFPIDGAFYALVLMSDGVYKCLEEATGTETSNLDIMCMvatemqQQTTLNGVAQAVVDKVGRYhhdkym
||...|           . |  ..|.|..     .. .   |.|.|||.. .|.. .  .. .  .. .      ..     .|. ..... |.      
Gdhflkknk.......klkepyitaepdvkv.vtltsedeflilaSDGlwdvlsnqevvdivrkllakg......ktndpqeaaelldeeairr......

eqfntCQKRDDMTLLV
      ...|..| .|
.....ggseDniTvvv
PPM_PTC7 51-333 5.2e-39 127.2 In-house 16-257 (259) alignment 
Range on Protein: 51-333
Range on HMM: 16-257/259.0
EDRSFHFN-------VDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMTdeevqlvlrqaffAVEKGFFQSIDD-ALAERTELqlqipeglssy
||. ....        |.  ...||||| |  .|..|...|.  | ...  ....              .||..  |.   ...|....           
edahialanlesssgkdsvaffavfdghggreaakyarehleeilkerksfeele.............klekalrksflaldtdeelks...........

eaykqyprqveRIQELqEHISGGTTAVVALIFNNKLYVANAGDSRALLCKQLEDSslqvQQLSKDHDTQNEEELLRLARLGLDIVQIQRNRRIGSQENTR
            ..   |....|.|||||||...||||||.|||||.||.. ..     .||..||...||.|  |. ..|  . .....|  |. ...|
...........seant.epstsGstAvvalitgsklyvAnvGDSravLcrsgnav....kqltedHkpsnedEreRiegaggsvsnvgngrvngvlavsR

SIGDYCVKGGYKdfdilshsAEEPVIADPHIVgGFPIDGAFYALVLMSDGVYKCLEEATGTETSNLDIMCMVATEMQQQTTLNGVAQAVVD
..||.. | ...         |..|.|.|.|    .||     |.|.|||.. .... .  .  .  .  . ..|  ...   ..|....|
afGdfelkpket........eeqlvsaePdis.stkideedefliLasdGlwdvvsdqeavdlvrselskkdpmeaaeklvdeaiargsed
PP2C Protein phosphatase 2C 59-330 1.1e-38 126.2 Pfam-A 31-250 (255) alignment 
Range on Protein: 59-330
Range on HMM: 31-250/255.0
VDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMTdeevqlvlrqaffAVEKGFFQSIDDALAERTELqlqipeglssyeaykqyprqveRIQEL
 ..  ...||||| |  .|..|...|.  | .|. .....              |||.. .|.  ...|....                      ...  
kssvaffavfdghggreaakyarehleeilkeqksflele.............kvekalrksfladtdeelks......................skant

qEHISGGTTAVVALIFNNKLYVANAGDSRALLCKQLEDSslqvQQLSKDHDTQNEEELLRLARLGLDIVQiqrNRRIGSQ-ENTRSIGDYCVKGGYkdfd
 |... |.|||||||...||||||.|||||.||.. ..     ..|..||....|.|  |. ..|  . .   | |.  . ...|..||...| ..    
.epsksGstavvalirgkklyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpke....

ilshsaEEPVIADPHIVgGFPIDGAFYALVLMSDGVYKCLEEATGTETSNLDIMCM-VATEMQQQTTLNGVAQA
      |..|.|.|..   ....     |.|.|||.. .|.. .  .  . ..  .  ..|. ...  ...|..
......eqlvsaePdvt.svklteedefliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaiarg
PP2C Protein phosphatase 2C 59-330 1.1e-38 126.2 In-house 31-250 (255) alignment 
Range on Protein: 59-330
Range on HMM: 31-250/255.0
VDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMTdeevqlvlrqaffAVEKGFFQSIDDALAERTELqlqipeglssyeaykqyprqveRIQEL
 ..  ...||||| |  .|..|...|.  | .|. .....              |||.. .|.  ...|....                      ...  
kssvaffavfdghggreaakyarehleeilkeqksflele.............kvekalrksfladtdeelks......................skant

qEHISGGTTAVVALIFNNKLYVANAGDSRALLCKQLEDSslqvQQLSKDHDTQNEEELLRLARLGLDIVQiqrNRRIGSQ-ENTRSIGDYCVKGGYkdfd
 |... |.|||||||...||||||.|||||.||.. ..     ..|..||....|.|  |. ..|  . .   | |.  . ...|..||...| ..    
.epsksGstavvalirgkklyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpke....

ilshsaEEPVIADPHIVgGFPIDGAFYALVLMSDGVYKCLEEATGTETSNLDIMCM-VATEMQQQTTLNGVAQA
      |..|.|.|..   ....     |.|.|||.. .|.. .  .  . ..  .  ..|. ...  ...|..
......eqlvsaePdvt.svklteedefliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaiarg
0049733 PP2C-like 49-360 5.8e-30 97.5 In-house 17-230 (235) alignment 
Range on Protein: 49-360
Range on HMM: 17-230/235.0
EFEDRSFHfnvdNTCLYGVFDGHDGASVADFAAQRLPAELLlqQLTDDMTDEEVQLVLRQAFFAVEKGFFQSiddalaertelqlqipeglssyeaykqy
. ||. .     .. |..|.||| |. ....|...|.  ||  .|  ... .... .||.|| |... ...                             
vneDavlv....glllfavaDGhgghaagevasellvetll..elllelllldleealrkaflaaneallel............................

prqverIQELQEHISGGTTAVVALIFNNKLYVANAGDSRALLCKqleDSslQVQQLSKDHDTQNEEELLRLARLGLDIvqiqrnRRIGSQENTRSIGDYC
       .. .|.  .||||||||....||||||.|||||.|..   |   ...||..||   ||.|  |. ..|  .      | .|.   ||..||..
......alaspelagmgtTavvalldggklyvanvGDsrayllr...dg..klvqltedhspvnelerqriitaggav......rvpgrlaltralGdll

VKggykdfdilshsaeepviadPHIVGGFPIDGAfyALVLMSDGVYKCLEEATGTETSNLdimcmvatemqqqTTLNGVAQAVVDKVGRyhhdkymeqfn
.|                    |...     .|    |.|.|||....|.. .  .. .              ..|. .|...|. . .           
lk....................pdvtvlelepgd..flllasDGlwdvlsdeeivdllrs.............ldleeaaerlvelala...........

tCQKRDDMTLLV
   .||..|..|
.rggrDNiTvvv
subfamily_PPM1A_pd Subfamily PPM1A 53-335 1.2e-29 96.5 In-house 34-264 (282) alignment 
Range on Protein: 53-335
Range on HMM: 34-264/282.0
RSFHfNVDNTCLYGVFDGHDGASVADFAAQRLPAELLLQ-QL----TDDMTDEEVQLVLRQAFFAVEKGFFQSIDDALA-ERTelqlqipeglssyeayk
 |.  .. .  .. ||||| |..||..... |....| . .|    ... ...||. .|||.|.|...   .. .|. . ...                 
aslg.alkdwsfFavfDGHaGsevakyvkkhllenileeeelkeaaleasekdevkealrqgfLaldeairelstdlktadks.................

qyprqveriqelqehisgGTTAVVALIFNNKLYVANAGDSRALLCKQLedsslQVQQLSKDHDTQNEEELLRLARLGLDIVqiqRNRRIGSQENTRSIGD
                  |.|||..|. ...|..||.|||||.||..      ... |..||  ....|  |.   |  .|    .|  |.   .|..||
..................GsTavtvlvsekhliianlGDsRavlcrng.....kaaflteDHkpsrpkEkkRieqAGGsvv...vsRvnGaLAvsRalGD

YCVKggykDFDIlSHSAEEPVIADPHIVGGFPIDGAFyALVLMSDGVYKCLeeatgtetSNLDIMCMVATEMQQQTTLNGVAQAVVDKV
| .|    . .   .. |  |.|.|..     ..     ||| .||..  |        |. ... .|........ |. ||.|.||| 
yeyk....eeee.kkaeeqlvsaepevtsierseedd.flvlacDGiwDvl........sdeevvelvrkrlevadeleevakalvdka
subfamily_PPM1G2_pd Subfamily PPM1G2 60-334 7.7e-28 90.2 In-house 50-263 (287) alignment 
Range on Protein: 60-334
Range on HMM: 50-263/287.0
DNTCLYGVFDGHDGASVADFAAQRlpaelllqqltddmtdeevqlvlrqaffavekgffqsIDDALAERTELQ-LQIPEGLSsyEAYKQYPRQVERIQEL
... |..||||| ||.|| .|...                                     .   .|......  .. . |   .|...  ... . ..|
kslalfavfDGhGGakvakyagkk.....................................likkiakkksfkegaleqilk..dafletDeellkdekl

QEHISgGTTAVVALIFNNKLYVANAGDSRALLCKQLEdsslqVQQLSKDHDTQNEEELLRLARLGlDIVqiQRNRRIGSQENTRSIGDYCVKGGYKdfdi
... . |.||||.|| ..||||||||||||.|... .     |..|| ||  |.|.|  |.   |  .|  . ||  |.    |..||.. | . |    
kdesa.GstavvvlikeeklyvanaGDsravlsskgn.....vkalsfDhkPqeesekkriiaag.Gfv..elnrvngnLalsralgDfefkknvk....

lSHSAEEPVIADPHIVGgFPIDGAFYALVLMSDGVYKCLeeatgtetSNLDIMCMVATEMQQQTTLNGVAQAVVDK
  .. |. | | | ..    .|     |||  ||.. .|        .| ... .| ........|. ... ..||
.kkpeeqivtavPDvlv.kkldeddeflvLaCDGiWDvl........tnkevvdlvrerlvsgakldeiieelldk
PPM_PTC7_SpoIIE 62-360 4.1e-21 68.8 In-house 34-226 (230) alignment 
Range on Protein: 62-360
Range on HMM: 34-226/230.0
TCLYGVFDGHDGASvaDFAAQRLPAELLLQQlTDDMTdeevqlvlrqaffaVEKGFFQ------------Siddalaertelqlqipeglssyeaykqyp
  ..|..||| | .   .|. .|   |  .  . ...                .  ..            .                             
alvvgdvdGhGgra..alamgllrtalrela.fagle..............kpeeilrrlnlalaadlede.............................

rqveriqelqeHISGGTTAVVALIFNNK--LYVANAGDSRALLCKQlEDSslqvqqlskdhdtqneeELLRLaRLGLDI-VQIQRNRRIGSQENTRSIGD
           ..|.|.|||||||....  |||||||||..||... ..                  |  |.  .|  . . |  .|  |... ....||
...........psssgaTavvalidpstgklyvanaGdsppllvrd.dgg.................ereri.vagglpslGilpgrvfgvlavslapGd

YCVKGgykdfdilshsaeepviadphivggfpidgafyalvlmSDGVYKCLEEaT-GTETSNL-DIMCMVATEMQQQTTLNGVAQAVVDKVGRYhhdkym
. ..                                       .|||  .  . |  .|. .  . . ...    .  ..  ....|.| ....      
lllly......................................tDGvveaepd.tsdgelfgkdeflilasdglwdvlspqelvdlvrdelekp......

eqFNTCQKRDDMTLLV
  ..  ...||.||||
..aaeglleDDitllv
subfamily_PPM1H_pd Subfamily PPM1H 55-219 7.2e-20 64.1 In-house 56-213 (404) alignment 
Range on Protein: 55-219
Range on HMM: 56-213/404.0
FHFNVDnTCLYGVFDGHDGASVADFAAQRLPAELL--LQQLTDDMTDEEVqlVLRQAFFAVEKGFFQSIDDALAERTELQLQIPEGlSSYEAYKQYPRQV
.. ... . ..|.|||| | ..|  |.. |   |   |..... .....     .. . ...|   .| ..   |..  . ..  | .  .|...   |.
eeeklp.layfglfDGhaGsgaalvaskllhkhlkekledvlellleksa..eeeenteesskespssvseiyeekeiskeeLviG.alesaflemDeqi

ERIQElQEHISGGTTAVVALIFNNKLYVANAGDSRALLCKQLEDsslqvQQLSKDHDTQNEEE-LLRL
.| .| . .|.|| ||.|||....||||||||||||.|... |      ..||.|.  . | . |..|
arere.ayrikGGCtalvalvllgklYvanaGDsRailvrkdei.....iplsadftPeteRqRlqel
subfamily_PPM1L_pd Subfamily PPM1L 50-296 3.1e-18 59.0 In-house 23-222 (269) alignment 
Range on Protein: 50-296
Range on HMM: 23-222/269.0
FEDRSFHFNVDNTCLYGVFDGHDGASVADFAAQRLPAElLLQQLTDDMTDEEVQLVlrqaffavekgffqsiddalaertelqLQIPEgLSSYEAYKQYP
||      |  .. ...||||| |   |.|| ..|. . ....| .  .| | ..                            ..  . |   |      
feieediknktgesffavfdGhGGefaaefakdvlvka.iknklieldadkentep...........................infsk.lltdeilsvde

RQVERIQELQEhIsGGTTAVVALIFNNKLYVANAGDSRALLCkqleDSSLQVQQLSKDHDTQNEEELLRLARLGLDIVQIQRNRRIGSQENTRSIGDYCV
. .|...  .. |  ||||..||. ...| ||| |||| .|.    | . .   || ||  |. .|  |. . |  |      |  |    .|..||| .
kllekakraed.i.aGttalialvqesdlivanvGdsrGvly....dkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdypl

KggykDFDIlshsaeepVIADPHIVGgFPIDGA-FYALVLMSDGVYKC
|    | ..        ||||| |.  | .|      |.| |||.. .
k....dknl........viadpdilt.fdlddhkpeflilasdGlwdt
subfamily_PDP_pd Subfamily PDP 143-251 4.9e-18 58.4 In-house 133-242 (398) alignment 
Range on Protein: 143-251
Range on HMM: 133-242/398.0
EAYKQYprQVERI-QELQEHISGgTTAVVALIFNNKLYVANAGDSRALLCKQLEDSSLQVQQLSKDHDTQNEEELLRLARLGLDIVQ---IQRNRRIGSQ
|| |.   . . . ..|.  .|| ..|..||| ...|.|||.||.||.|..| |..| .. .||||. ..||||. |. .   .  .   |...| .|. 
ealkkl..kekslreallvalsG.acallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeL

ENTRSIGDYCVKG
  .|  ||.  | 
qPlRAFGdvryKw
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 58-296 5.9e-18 58.1 In-house 32-210 (255) alignment 
Range on Protein: 58-296
Range on HMM: 32-210/255.0
NVDNTCLYGVFDGHDGASVADFAAQRLPAeLLLQQLTDDMTdeEVQLVLRQAFFAVEKGFfqsiddalaertelqlqipeglssyeaykqyprqveriQE
. ..  .| .|||| | . |.||...|.  .| . |    .  . . .|..|. ...  .                                      .|
dksdedyyalfdGhgGraaakfaseelyk.ilaelldlnna..nPvkslkkaykeistqi......................................se

LQehISGGTTAVVALIFNNKLYVANAGDSRALLCKQledsSLQVQQLSKDHDTQNEEELLRLARLGLDIVQIQRNRRI-GSQENTRSIGDYCVKGgYkdf
    .  ||||...|| ..| |.|| ||||..||..        ..|| ||  ..|.| .|...||  .|. .   |. |    .|..||  ..  .   
rp..kfiGttaasvliiedkvyianvGdsrvvlcqk....dgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsfleP.f...

dilshsaeepVIADPHIVGGFPIDGAFYALVLMSDGVYKC
          |..||.. . . |      |.|  ||..  
..........vvpdPdlsqsleiskkdkflilacdGiwdl
subfamily_ILKAP_pd Subfamily ILKAP 163-250 1.1e-17 57.2 In-house 112-197 (293) alignment 
Range on Protein: 163-250
Range on HMM: 112-197/293.0
SGGTTAVVALIFNNKLYVANAGDSRALLCKQLEDSS-LQVQQLSKDHDTQNEEELLRLARLGldiVQIQRNRRIGSQENTRSIGDYCVK
  |.||.| |. .| ||||| |||.|.|... |... ... .|.|||.. ..||  |. . |    ... .|  |  | .|||||   |
kdGstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaG...gvvrdgrvlGvlevsrsiGdgrfk
subfamily_PPM1E_pd Subfamily PPM1E 158-304 2.2e-17 56.1 In-house 96-222 (265) alignment 
Range on Protein: 158-304
Range on HMM: 96-222/265.0
LQEHISGGTTAVVALIFNNKLYVANAGDSRALLCKQLEdsslqVQQLSKDHDTQNEEELLRLARLGLDIVQIQRNRRIGSQENTRSIGDYcvkggykdfd
 .|.. .|.||||.|| ...||||  |||.|||... |     . || | |  ..|.|  |.. .|  .|.|   |  |.   .|.|||.          
ereklksGstavvvliekdqlyvaWlGDsqallvrkge.....avqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDv..........

ilshSAEEPVIADPHIVgGFPIDGAFYALVLMSDGVYKCLEEATGTE
    . .. |.... ..  ...||. . |.| .||..  ..| . ..
....klkpyvsgeadva.eveldgseeylilacDGlwDvvneeevvk
subfamily_PPM1G_pd Subfamily PPM1G 163-297 9.2e-17 54.2 In-house 295-416 (473) alignment 
Range on Protein: 163-297
Range on HMM: 295-416/473.0
SGGTTAVVALIFNNKLYVANAGDSRALLCKQledssLQVQQLSKDHDTQNEEELLRLARLGldiVQIQRNRRI-GSQENTRSIGDYCvkggYKDFDILSH
. ||||||||. ..||.||||||||. |...      .  .|| ||  ..|.|| |. . |    ... . |. |     | .||..    ||    | .
dsGttAvvaLlkekklivAnaGDsRcvlsrn.....GkAldlslDHkPeDevEleRiekAG...GkvdedgRvnGGLnlsRAlGDha....YkkneeLpl

SaEEPVIADPHIVGGfPIDGAFYALVLMSDGVYKCL
  |  . | | |     .  .   ||| .||.. ..
k.eqmisAlPDikvl.tlteedeFlvlAcDGiWnvm
subfamily_PPM1D_pd Subfamily PPM1D 163-305 1.5e-13 43.5 In-house 107-260 (309) alignment 
Range on Protein: 163-305
Range on HMM: 107-260/309.0
SGGTTAVVALIFNNKLYVANAGDSRALLCKQLE-DSSLQVQQLSKDHDTQNEEELLRLARLGLDIVQIQ---R---NR-RIGSQEN--TRSIGDYCVKGG
  |||| | .| ..|||||. |||...| .. . ...|. ..| |||  .. ||  |...|| .. . .   |   .| |. ....  . .|    |   
taGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGevaaksGvkRvvWkRprlehngptvideiPFLavaRs

YKDFDILSHSAEEPVIADPHIVGGFPIDGAFY-ALVLMSDGVYKCLEEATGTET
  |.   ..  .| |.     |  . .|..    ..| |||....|. ..  ..
lGDlWsynaksgefvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsv
subfamily_PP2D1_pd Subfamily PP2D1 168-349 4.1e-12 38.6 In-house 180-337 (492) alignment 
Range on Protein: 168-349
Range on HMM: 180-337/492.0
AVVALIFNNKLYVANAGDSRALLCKQleDsslQVQQLSKDHDTQNEEELLRLARLGLDIVQIQRNRRI-GSQENTRSIGDYcvkGgykDFDiLshsaEEP
  | |.    ||.||||. .|.||..      .  .| ..|...|..|  |. . |  .|. ..| .. |  ..|| .| |   |   | . |    .. 
sevhleelgvlyianaGnvqAvLcre..G...kaiiLtreHtprnkkERtRvekagsvvvkseknglvnGildttRGLGny...G...dpk.L....kks

VIADPHIVgGFPIDGAFYALVLMSDGVYKCLEEATGTETsNLDIMCMVATEMQQQTTLNgvaqavvDKVGRYHHDKYMEQFNT
|| .|..    ..| |   ||| | |... |.|   ..    ... .   .....   .        .|  . .| ..| . .
vipePktt.svkldeaaqflvlAsnGlWevlseeevlsL.vkqtlaiyksrvraenvpd.......sdvttvgedylgEleak
subfamily_PPM1K_pd Subfamily PPM1K 154-250 5.4e-12 38.4 In-house 88-182 (263) alignment 
Range on Protein: 154-250
Range on HMM: 88-182/263.0
RIQELQEHISGGTTAVVALIFN-NKLYVANAGDSRALLCKQLEdsslqVQQLSKDHDTQNEEELLRLARLGLDIV--QIQRNRRIGSQENTRSIGDYCVK
     .|. | |||| |.|. . ..| .|. |||||.||.. .      ..|..||| . |||  |. . |  .    ... .  |    |||.||  .|
fsvaeaellssGttatvsllrdGtelvlaslGdsrailcrnGk.....akkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtrslGdldlk
subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 158-243 6.2e-12 38.6 In-house 79-164 (292) alignment 
Range on Protein: 158-243
Range on HMM: 79-164/292.0
LQEHISGGTTAVVALIFNN-KLYVANAGDSRALLCKQLEDSSLQVQQLSKDHDTQNEEELLRLARLGLDIvQIQRNRRIGSQENTRS
...  |..|..| | . .. .|..|| ||||||| . |  |  ... ||.||  .. .|  |. | |  . .  | |  | .  .| 
idaresattavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraGGrv.eptrvrgwgfrGtarv
subfamily_KAPP-like_pd Subfamily KAPP-like 154-303 1.1e-10 34.1 In-house 89-225 (266) alignment 
Range on Protein: 154-303
Range on HMM: 89-225/266.0
RI-QELQEHISGGTTAVVALIFNN----KLYVANAGDSRALLCKQLEdsSLqvqQLSKDHDTQNEEELLRLARLGLDIVQIQrnRRIGSQENTRSIGDYC
 . ..|...   |.|| .||....     | ||| ||| |.|..  |  ||   .||||| ....||  |.   |. . . |   ||     .|..||. 
evdaklkdfeyeGatatlalvwsdGqqrylqvanvGdssaflsrGne..sl...elskdhkakdpeekqrikddGitlsdnq..trinGlavsralGdhf

VKggykDFDIlshsaeePVIADPHIVGGFPIDGAFYALVLMSDGVYKCLEEATGT
.|    . .|        .|..|..   . .      |.. |||..  ..     
ik....elni.......GlisepyvsnrilltpfdkflivasdGlwdvisGkdai
subfamily_PPM1G_pd Subfamily PPM1G 43-118 2.9e-09 29.4 In-house 28-100 (473) alignment 
Range on Protein: 43-118
Range on HMM: 28-100/473.0
GRREEHEFEDRSFHFNVDNTCLYGVFDGHDGASVADFAAQRLPAELlLQQltDDMTDEEVQLVLRQAFFAVEKGFF
| |...|  . .     ..| |..|.||| |. || . |..||  |  .|      ...|.  |..||.|...   
GwrvsqEDahncitdldedtslfavyDGHGGkevakyvakklpdll.kaq..kgykegdvekaleeaflalDeklk
subfamily_PPM1K_pd Subfamily PPM1K 43-131 6.6e-09 28.3 In-house 13-96 (263) alignment 
Range on Protein: 43-131
Range on HMM: 13-96/263.0
GRREEHefEDRSFHFNVDNTCLY-GVFDGHDGASVADFAAQRLpaELLLQQLTDdmTDEEVQLVLRQAFFAVEKGFFQSIDDALAERTEL
|.|.|   |||    ..|.  || .||||| |.. |||. ..|  |  |..| .   ..... ||..||  ..| . . .   .||...|
Gkraen..edriklkeldpellyvavfdGhaGsaaadfvhdkl..ekilkrlle..kekdleivlknafeeldkklkrylefsvaeaell
subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 157-304 1.4e-08 26.9 In-house 97-236 (276) alignment 
Range on Protein: 157-304
Range on HMM: 97-236/276.0
ELQEHISGGTTAVVALIFNNK----------LYVANAGDSRALLCKQLEdsSLqvqQLSKDHDTQNEEELLRLARLGLDIVQIQrnRRIGSQENTRSIGD
.|...   |.|| .||....           | ||| ||| |.|..  |  ||   .||||| ... ||  |.   |. . . |   ||     .|..||
klkdfeyeGatatlalvwsdGeeqqqqqqrylqvanvGdssaflsrGne..sl...elskdhkatdpeekqrikddGitlsdnq..trinGlavsralGd

YCVKggykDFDIlshsaeePVIADPHIVGGFPIDGAFYALVLMSDGVYKCLEEATGTE
. .|    . .|        .|..|..   . .      |.. |||..  ..     |
hfik....elni.......GlisepyvsnrilltpfdkflivasdGlwdvisGkdaie
subfamily_PP2D1_pd Subfamily PP2D1 55-104 4.2e-08 25.3 In-house 26-72 (492) alignment 
Range on Protein: 55-104
Range on HMM: 26-72/492.0
FHFNVDNTCLYGVFDGHDGASVADFAAQRLPaELLLQQLTDdmTDEEVQL
 . |  |.| .|..||. ||. |. ||. |. |.||..|     ||.|.|
yfgndvnscFfgiyDGynGataAeiaakelh.evlleelek..vdervsl
PP2C_SIG_SM00331 54-202 1.3e-07 24.4 In-house 20-122 (217) alignment 
Range on Protein: 54-202
Range on HMM: 20-122/217.0
SFHFNVDNT--CLYGVFDGHD-GASVADFAAQRLpaELLLQQLTDDmtdEEVQLVLRQAFFAVEKGffqsiddalaertelqlqipeglssyeaykqypr
....  .|    |. |.||.. |.  | ...| .  ..| ..|...   ||.. .|...  |...                                   
yydvvklnegrlllvvaDgmGkGlaAaaassqlr..talrellseg...eelsqalkrlnraiyee..................................

qveriqelQEHISGGTTAVVALI--FNNKLYVANAGDSRALLCKqledSSLQVQ
        .|  ....|...||.   ..||..||||||| .|      .. .|.
........keekgmfaTlllalydfssgklsyanaGdsrpyllr....dgklve
subfamily_ILKAP_pd Subfamily ILKAP 58-120 2.4e-07 23.2 In-house 39-103 (293) alignment 
Range on Protein: 58-120
Range on HMM: 39-103/293.0
NVDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMTD--EEVQLVLRQAFFAVEKGFFQS
.| . . |.||||| |   ..|||..|  ..| .   .|..   .|..  | ..| .... |.. 
lvsrvsyyavfdGhaGsrasefaaeklhkkileklpksdvsakekeikkclvdsfkktdeefLkl
subfamily_PPM1E_pd Subfamily PPM1E 60-120 2.9e-07 22.9 In-house 38-94 (265) alignment 
Range on Protein: 60-120
Range on HMM: 38-94/265.0
DNTCLYGVFDGHDGASVADFAAQRLPAeLLLQQLTdDMTDEEvqLVLRQAFFAVEKGFFQS
...  ..||||| |   |..||..|.  || .| . . .| .    |..|| .... | | 
keraffavfDGHgGveaakyaaahlhe.llvrqek.lkedpa..ealkeafkltDerflqk
subfamily_Choan-PPM-1_pd Subfamily Choan-PPM-1 54-298 4.2e-07 21.4 In-house 18-270 (317) alignment 
Range on Protein: 54-298
Range on HMM: 18-270/317.0
SFHFNVDNTCLYGVFDGHD--GASVADFAAQRLPAelLLQQLTDDMTDEEVQLVLRQAFFAVEKGFFQSIDDALAERTEL----QLQI---PEGLSSYEA
||. . .  .|  |||||   |   |  |.  | |  || .|. |   .| .  |.. |  ..    .. |   || . .    .|..      ..  . 
sfklaGhrialaavfdGhsllGeiaaamardtlta..llPelvwdslltePeqllkeifarldaaivaaydapPaeyeyigqsGsldfrleahaiaeldp

YKQYpRQVERIQELQEHISGGTTAVVALIFNNK-LYVANAGDSRAL--LC--KQ-LEDSSLQVQQLSKDHDTQNEEELLRLARLGLDIVQIQRNRRIGSQ
 | |   . | .   . .  |||||||.. ..  . ||||||. ||  |    . ..   |.|. ||. |. . ..|  |.|    .   .  .  .  .
Pkgy.vcisrddvptrPldfGttavvavvvdethvvvanaGdaaalvllrdqaghedrdGlsvealsvrhtlrskaerarvaevlpgaahvtedgylail

ENTrsIGDYCVKGGYK-DFDILShsaEEPVIADPHIVG-GFPIDgAFYALVLMSDGVYKCLE
...  . .| ..         |.      |||||..    ...|   .|.| .|||.   |.
dea..laayelqltkslGhkllk...raGviadPevrsrvldvd.evfavvvvsdGitdelk
PP2C_2 Protein phosphatase 2C 51-301 4.9e-07 22.2 Pfam-A 13-185 (212) alignment 
Range on Protein: 51-301
Range on HMM: 13-185/212.0
EDRSFHFNVDN-TCLyGVFDGHDGASVADFAAQRLpAELLLQQLTDDMTDEEVQLvlrqaffavEKGFFQSIDDALAERTElqlqipeglssyeaykqyp
.|...... ..  .|  | ||.  |. .| .|. . .| ....|.. ...|. |          |. ....|  .. . ..                   
qDalaireasdgwll.aVADGaGsakrSdkGarla.veaagealeklleeeseqe.........eeallrqieneilasvk...................

R---QVERiqeLQEHISGGTTAVVALIFNNKLYVANAGDSRALLCKqlEDSSLQVQQLSKDHDTQNEeellrL-----ARLGLDIvqiqrnrrigsqent
    . ..    .|  . .|| ..|.| ........ ||..... .  .|...|.   .. .. .||     .     .  . .                
lkqeaeaq...qeelkdyatTlllavitpgeivffqiGDgaivvrd..rdgevqllgepdsgeyane.....ttfltsedaeeel...............

rsigdycvkggykdfdilshsaeepviadphIVGGFPiDGAFYALVLMSDGVYKCLEEAT
                                .  ..   .. ||.||.||| . |.. .
...............................rirrlk.lepgdalllmTDGvsdslrkee
PP2C_2 Protein phosphatase 2C 51-301 4.9e-07 22.2 In-house 13-185 (212) alignment 
Range on Protein: 51-301
Range on HMM: 13-185/212.0
EDRSFHFNVDN-TCLyGVFDGHDGASVADFAAQRLpAELLLQQLTDDMTDEEVQLvlrqaffavEKGFFQSIDDALAERTElqlqipeglssyeaykqyp
.|...... ..  .|  | ||.  |. .| .|. . .| ....|.. ...|. |          |. ....|  .. . ..                   
qDalaireasdgwll.aVADGaGsakrSdkGarla.veaagealeklleeeseqe.........eeallrqieneilasvk...................

R---QVERiqeLQEHISGGTTAVVALIFNNKLYVANAGDSRALLCKqlEDSSLQVQQLSKDHDTQNEeellrL-----ARLGLDIvqiqrnrrigsqent
    . ..    .|  . .|| ..|.| ........ ||..... .  .|...|.   .. .. .||     .     .  . .                
lkqeaeaq...qeelkdyatTlllavitpgeivffqiGDgaivvrd..rdgevqllgepdsgeyane.....ttfltsedaeeel...............

rsigdycvkggykdfdilshsaeepviadphIVGGFPiDGAFYALVLMSDGVYKCLEEAT
                                .  ..   .. ||.||.||| . |.. .
...............................rirrlk.lepgdalllmTDGvsdslrkee
subfamily_PPM1D_pd Subfamily PPM1D 61-121 8e-07 21.4 In-house 34-94 (309) alignment 
Range on Protein: 61-121
Range on HMM: 34-94/309.0
NTCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMTDEEVQLVLRQAFFAVEKGFFQSI
.    .||||| |   | || ..|  ..  |.      .|.|.  .|.||.|...   .. 
evafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkkl
PPM_PTC7_SpoIIE_motif 286-360 9.9e-07 22.4 In-house 15-77 (81) alignment 
Range on Protein: 286-360
Range on HMM: 15-77/81.0
LVLMSDGVYkcleEATgTETSNL----DIMCMVATEmQQQTtLNGVAQAVVDKVGRyhhdkymeqfnTC--QKRDDMTLLV
|.|..||..    ||  .....|    . . ..... .... |  .|...||.|..           ..  ...||.||||
llLyTDGlt....Ear.dsdgelfgkeellrladra.egks.lqeladklvdevle...........ngsgereDDitllv
SpoIIE Stage II sporulation protein E (SpoIIE) 286-360 5.8e-06 18.3 Pfam-A 127-189 (193) alignment 
Range on Protein: 286-360
Range on HMM: 127-189/193.0
LVLMSDGVYKCLeeATGTETSNLDIMCMVATEMQQQTtLNGVAQAVVDKVGRyhhdkymeqFNTCQKRDDMTLLV
|.|..|||.     . ..|. ...  . ...| .... |  ...|.|... .         ..  ...||.||||
lllyTDGvtEar..dpdgelfgkerllallaeaeges.leelldalveelle.........lgsgeleDDitllv
SpoIIE Stage II sporulation protein E (SpoIIE) 286-360 5.8e-06 18.3 In-house 127-189 (193) alignment 
Range on Protein: 286-360
Range on HMM: 127-189/193.0
LVLMSDGVYKCLeeATGTETSNLDIMCMVATEMQQQTtLNGVAQAVVDKVGRyhhdkymeqFNTCQKRDDMTLLV
|.|..|||.     . ..|. ...  . ...| .... |  ...|.|... .         ..  ...||.||||
lllyTDGvtEar..dpdgelfgkerllallaeaeges.leelldalveelle.........lgsgeleDDitllv