Gene SHB17 in Saccharomyces cerevisiae

Synonym: YKR043C, SHB17

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily HP1-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP043_AA protein Get Run
ScerP043_AA_3-193 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_TIGAR_pd Subfamily TIGAR 7-196 3.3e-64 208.6 In-house 2-185 (222) alignment 
Range on Protein: 7-196
Range on HMM: 2-185/222.0
RCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFrNnqflnpDNITYIFTSPRLRARQTVDLVLKPLSDEQRAKirVVVDDDLREWEYGDYE
..|.||||.||..|.....| ||.||...|. |..|...... |      ..|.|||.|..|||.||....||.|....|..  |..|..|||.|||.||
ilivVrhGetefnkekilqgqtdtpLsekGveQakrvakrLs.n......ekinyifsSdllRAkqTaeiilkalkekkrea..verdkrLrEreyGvye

GMLTREIIELRKSRGldkerpwNIWRDGCENGETTQQIGLRLSRAIARI--QNLHRK-----HQSEGRASDIMVFAHGHALRYFAAIWFGL---GVQKKC
|. ..|. ||.|..|       |.... .|.||...|. |||..|....  ..||..     ...||......|..||.|||....... .   | ... 
Gvaldelrellkaag.......nvpsfvpegGesieqlelrlvaaleelcakilhleadkkkdgaegelthvlvvshglalrellnvlhvelsvgklrla
0043909 Phosphoglycerate mutase-like 6-193 4.1e-41 133.4 In-house 3-204 (249) alignment 
Range on Protein: 6-193
Range on HMM: 3-204/249.0
PRCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNnqflnPDNITYIFTSPRLRARQTVDLVLKPLSDEQrakIRVVVDDDLREWEYGDY
.| ..||||.|||.. |...| .| |||. |. |. ..|| . ..       .......|| .||.||  ..|. |  ..   . |.||..|||. .|..
krlyLvRHGetewnaegrfqgwlDspLtelGreqaralgealkel.....gipfdavysSplkRAiqTaeiileelgldk...lpvevdprLrErdfGal

EGMLTREIIELRKSR---------------------------GLDKERPWNIWRDGCENGETTQQIGLRLSRAIARIQNLHRkhqseGRASDIMVFAHGH
||. . || |                                   . ...... | . .||. ...  |. .|. .. . .       . ......|||.
egltkaeiaekypeelvawlrrsydvlpplleeldelllellldyaladldplldrppggEsladvvaRvlpaleellarll.....kdggnvliVaHgg

ALRYFAAIWFGLGVQ
.||...| ..||...
vlrallayllglsle
0036777 Phosphoglycerate mutase-like 6-193 4.8e-41 133.3 In-house 3-200 (247) alignment 
Range on Protein: 6-193
Range on HMM: 3-200/247.0
PRCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNnqflnPDNITYIFTSPRLRARQTVDLVLKPLSDEqraKIRVVVDDDLREWEYGDY
 | ..||||.|||...|...| .| |||. |. |. ..|| . ..       .......|| |||.|| ...|. |  .   ...||||..|||. ||..
krlyLvRHGetewnaegrfqgwlDvpLtelGreqakalgellkel.....glpfdavysSpllRAiqTaeiilealgls...llpvvvdprLrErdyGal

EGMLTREIIEL------RKSRGLDKERP-----------------WNIWRDGCENGETTQQIGLRLSRAIARIQNLHRkhqseGRASDIMVFAHGHALRY
||.   || |       .  |.    ||                 .....|.. .||. ...  |. .|. .. . .       . ....|..||..||.
egltkaeiaekypeelvawwrdpydyrppllelllelllldllryallpldllpggEsladvvaRvlpaleellarll.....kdgenvlvVsHggvlra

FAAIWFGLGVQ
..| ..||...
llayllglsle
0049178 Phosphoglycerate mutase-like 6-193 5.2e-40 129.9 In-house 4-199 (243) alignment 
Range on Protein: 6-193
Range on HMM: 4-199/243.0
PRCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNnqflnPDNITYIFTSPRLRARQTVDLVLKPLsdeQRAKIRVVVDDDLREWEYGDY
 | ..||||.|||.. | ..| || |||. |. |. ..||   ..       .......|| .||.|| ...|. |   .. ...||||..|||. .|..
trlyLvRHGetewnaegrlqgwtDspLtelGreqAralgellael.....glkfdavysSplkRaiqTaeiileal...glpllpvvvdprLrErdfGal

EGMLTREIIEL---------------------RKSRGLDKERPWNIWRDGCENGETTQQIGLRLSRAIARIQNLHRkhqseGRASDIMVFAHGHALRYFA
||.   || .                      . . .|.. ... ...|.. .||. ...  |. .|. .. . .       . ....|.|||...|...
egltkaeiaakypeelvawwrdpydarppalllldlllplldrlladldllpggEsladvaaRvlpaleellaell.....hdgktvlvVaHggvirall

AIWFGLGVQ
| ..||...
alllglple
0050036 Phosphoglycerate mutase-like 7-193 8.1e-39 124.9 In-house 2-150 (171) alignment 
Range on Protein: 7-193
Range on HMM: 2-150/171.0
RCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVfrnnqflnpdNITYIFTSPRLRARQTVDLVLkplsdeqrakIRVVVDDDLREWEYGDYE
| ..||||.|||.. | ..| ||.|||. |. |. ..||            .......|| |||||| .|.|          ..|.||..|||. .|..|
rlyLvRHGetewnlegrfqgwtdvpLtelgraqaralgell..........pfdavysSpllRArqTaelil..........lpvivdprLrErdfGawe

GMLTREIIELRKSrgldkeRPWNIWRDGCENGETTQQIGLRLSRAIARIQnlhrkhqsegraSDIMVFAHGHALRYFAAIWFGLGVQ
|. . || .          . ...... . .||. ..   |. .|....             ....|.|||...|...|...||...
gltldeiaakype......wlldlldlappggEsladvlaRvlpaleell............gnvlvvaHggvirallalllglsle
0048955 Phosphoglycerate mutase-like 6-193 1.1e-38 125.8 In-house 1-198 (240) alignment 
Range on Protein: 6-193
Range on HMM: 1-198/240.0
PRCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNnqflnPDNITYIFTSPRLRARQTVDLVLKPLSDEQrakIRVVVDDDLREWEYGDY
|| ..||||..||.. | ..| || |||. |. |. ..||   ..       .......|| |||.|| ..... |. ..   ..||||..|||. .|..
prlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerLadl.....gikfdlvysSpllRaiqTaeiiaealglpl...lpvvvdprlrErdfgal

EGMLTREIIELRKSR-GLDKERPWNIWRDGC----------------------ENGETTQQIGLRLSRAIARIQNLHRKhqsegRASDIMVFAHGHALRY
||..  || |. .    |  ..|....  ..                       .||. ...  |. .|. .. . . |     . ....|..||...|.
egltldeiaekfpeelvlwlrdpldvrppllelldellllldlryalldedllpggEsladvaaRvlaaleellaralk.....pgknvlvVsHggvira

FAAIWFGLGVQ
. | ..||...
llayllglple
0037864 Phosphoglycerate mutase-like 4-193 1.5e-38 124.6 In-house 6-180 (211) alignment 
Range on Protein: 4-193
Range on HMM: 6-180/211.0
LTPRCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNnqflnPDNITYIFTSPRLRARQTVDLVLKPLSDEqraKIRVVVDDDLREWEYG
|. | ..||||.|||.. | ..| .| |||. |. |. ..|| . ..       .......|| |||.|| ...|. |. .   ...|.||..|||. .|
lmtrlyLvRHGetewnaegrlqgwldvpLtelGreqaralgealadl.....glpfdavysSpllRaiqTaeiilealglp...llpvevdprlrErdfg

DYEGMLTREIIElrKSRGLDKERPWNIWRDGCENGETTQQIGLRLSRAIARIQNLHRKhqsegRASDIMVFAHGHALRYFAAIWFGLGVQ
..||. . || |  |   .   . .. . . ...||. ...  |. .|.... . . |     . ....|..||..||...| ..||...
alegltleeiae..kypeelvawlrdpydfrppggEsladvvaRvlpaleellarllk.....dgenvlvVsHggvlrallayllglsle
0036887 Phosphoglycerate mutase-like 6-193 8.9e-38 122.2 In-house 2-167 (202) alignment 
Range on Protein: 6-193
Range on HMM: 2-167/202.0
PRCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFrnnqflnPDNITYIFTSPRLRARQTVDLVLKPLSdeqrakIRVVVDDDLREWEYGDY
 | ..||||.|||.. | ..| .| |||. |. |. ..|| .          .......|| |||.||...... |.      . |.||..|||. .|..
trlyLvRHGetewnvegrlqgdldvpLtelGreqaralgerla.......glpfdavysSpllRaiqTaeiiaealg......lpvivdprlrEidfgal

EGMLTREIIElrKSRGLDKERPWNIWRDGCENGETTQQIGLRLSRAIARIQNLHrkhqsegRASDIMVFAHGHALRYFAAIWFGLGVQ
||. . || |  |   . . . .. .   . .||. ...  |. .|.... . .       . ....|..||..||...| ..||...
egltleeiae..kypeelaawlrdpydfrppggEsladvvaRvlaaleellarl.......dggnvlvVsHggvlrallayllglsle
0035570 Phosphoglycerate mutase-like 8-193 3.3e-37 120.4 In-house 2-158 (219) alignment 
Range on Protein: 8-193
Range on HMM: 2-158/219.0
CIIVRHGQTEWSKSGQYTGltDLPLTPYGEGQMLRTGESVFRNnqflnPDNITYIFTSPRLRARQTVDLVlkplsdeqraKIRVVVDDDLREWEYGDYEG
 ..||||.||| ..|...|  | |||. |. |. ..||   ..       .......|| |||.|| ...          .. |..|..|||. .||.||
lyLvRHGetewnlegrlqg..dvpLterGreqaralgealadl.....gipfdavysSpllRaiqTaeii..........glpveidprLrEidfgdleg

MLTREIIELRKsrGLDKERPWNIWRDGCENGETTQQIGLRLSRAIARIqnlhrkhqseGRASDIMVFAHGHALRYFAAIWFGLGVQ
. . || |.    .. . . .. ..  . .||. ...  |. .|....           . ....|..||. .|...| ..||...
ltldeiaekyp..eelaawlrdpydyrppggEsladvvaRvlpaleel..........edgenvlvVsHggvirallayllglple
0051064 Phosphoglycerate mutase-like 6-193 3.4e-37 121.0 In-house 4-201 (241) alignment 
Range on Protein: 6-193
Range on HMM: 4-201/241.0
PRCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNnqflnPDNITYIFTSPRLRARQTVDLVLKPLSDEqraKIRVVVDDDLREWEYGDY
.| ..||||..||.. | ..| || |||. |. |. ..||   ..       .......|| |||.|| ..... |. .   ...||||..|||. .|..
krlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerladl.....gikfdavysSpllRaiqTaeiiaealglp...llpvvvdprlrEidfgal

EGMLTREIIEL-RKSRGLDKERPWNIWRDGC----------------------ENGETTQQIGLRLSRAIARIQNLHRkhqS-EgraSDIMVFAHGHALR
||..  || |. ..   .  ..|.... ...                       .||. ...  |. .|. .. . .      .   ....|..||...|
egltleeiaekfpeelvawlrdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleellarll...ldg...knvlvVsHggvir

YFAAIWFGLGVQ
.. | ..||...
allayllglple
0039931 Phosphoglycerate mutase-like 9-193 2.4e-35 114.3 In-house 3-158 (219) alignment 
Range on Protein: 9-193
Range on HMM: 3-158/219.0
IIVRHGQTEWSKSGQYTGltDLPLTPYGEGQMLRTGESVFRNnqflnPDNITYIFTSPRLRARQTVDLVlkplsdeqraKIRVVVDDDLREWEYGDYEGM
..||||.|||.. | ..|  | |||. |. |. ..||   ..       .......|| |||.|| ...          .. |..|..|||. .||.||.
yLvRHGetewnvegrlqg..dspLterGreqaralgerlkdl.....glpfdavysSpllRaiqTaeii..........glpveidprLrEidfgdlegl

LTREIIELRKsrGLDKERPWNIWRDGCENGETTQQIGLRLSRAIARIQNlhrkhqsegrASDIMVFAHGHALRYFAAIWFGLGVQ
   || |.     .   . .. ..  . .||. ...  |. .|.... .           ....|..||. .|...| ..||...
tleeiaekyp..eelaawlrdpydyrppggEsladvvaRvlpaleella..........genvlvVsHggvirallayllglsle
0053607 Phosphoglycerate mutase-like 9-193 1.2e-33 108.6 In-house 5-160 (191) alignment 
Range on Protein: 9-193
Range on HMM: 5-160/191.0
IIVRHGQTEWSKSGQYTGltDLPLTPYGEGQMLRTGESVFRNnqflnPDNITYIFTSPRLRARQTVDLVlkplsdeqraKIRVVVDDDLREWEYGDYEGM
..||||.|||.. | ..|  | |||. |. |. ...|   .        .......|| |||||| ...          .. |.||..|||. .||.||.
yLvRHGetewnaegrlqg..dvpLtelGreqaralaellael.....glkfdavysSpllRarqTaeii..........glpvevdprlrEidfgdwegl

LTREIIELRKSrgLDKERPWNIWRDGCENGETTQQIGLRLSRAIARIQNlhrkhqsegrASDIMVFAHGHALRYFAAIWFGLGVQ
   |. |      .   . .. .   . .||. ...  |. .|.... .           ....|.|||...|...| ..||...
tleelaekype..elaawlrdpldyrppggEsladvaaRvlpaleella..........ggnvlvVaHggvirallayllglple
His_Phos_1 Histidine phosphatase superfamily (branch 1) 8-183 1.2e-30 99.6 Pfam-A 2-158 (158) alignment 
Range on Protein: 8-183
Range on HMM: 2-158/158.0
CIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESvFRNnqflNPDNITYIFTSPRLRARQTVDLVLKPLSdeqrakIRVVVDDDLREWEYGDYEG
 ..||||..||.|.|...| .| |||..|. |. ..|.. ...    . ..|. ..||| .||.||....|. |.      |..  ...|||. .|..||
lylvRHGesewnkegrlqgwsdvpLtekGreqarelgkk.Lkr....adlpidavytSplkRaiqTaeilleeld......ipiikeprLrerdfgeweg

MLTREIIELRKsrglDKERPWNI--WRDGCENGETTQQIGLRLSRAIARIQNlhrkhqSEGRASDIMVFAHGHALRYF
. ..|. |  .    .... |.   ..   ..||. ...  |..... .. .       . .. ......||. || .
lpkeevkeefp....eeyekwkrdkkefrppegesladvyeRvapfleelie......akdkgenvlivsHggvlral
His_Phos_1 Histidine phosphatase superfamily (branch 1) 8-183 1.2e-30 99.6 In-house 2-158 (158) alignment 
Range on Protein: 8-183
Range on HMM: 2-158/158.0
CIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESvFRNnqflNPDNITYIFTSPRLRARQTVDLVLKPLSdeqrakIRVVVDDDLREWEYGDYEG
 ..||||..||.|.|...| .| |||..|. |. ..|.. ...    . ..|. ..||| .||.||....|. |.      |..  ...|||. .|..||
lylvRHGesewnkegrlqgwsdvpLtekGreqarelgkk.Lkr....adlpidavytSplkRaiqTaeilleeld......ipiikeprLrerdfgeweg

MLTREIIELRKsrglDKERPWNI--WRDGCENGETTQQIGLRLSRAIARIQNlhrkhqSEGRASDIMVFAHGHALRYF
. ..|. |  .    .... |.   ..   ..||. ...  |..... .. .       . .. ......||. || .
lpkeevkeefp....eeyekwkrdkkefrppegesladvyeRvapfleelie......akdkgenvlivsHggvlral
subfamily_PGAM_pd Subfamily PGAM 7-114 6.4e-17 53.7 In-house 2-101 (248) alignment 
Range on Protein: 7-114
Range on HMM: 2-101/248.0
RCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNNqFlnpdNITYIFTSPRLRARQTVDLVLKPLsdeQRAKIRVVVDDDLREWEYGDYE
. ...|||..|..|  ...| .|  |.. |. .  ..|. . ..| .    ..  ..|| . ||.||....|. |   ...|| |. .  |.|  ||. .
klvllRhGeselnkenkfcgwvDakLsekGkeeAkkagkalkqan.l....efdivytSvlkRaqqTlevileel...dqekiPvektwrLnErhyGalt

GMLTREII
|.  .|..
glnkaeva
0047369 Phosphoglycerate mutase-like 9-95 2.9e-10 33.0 In-house 49-171 (438) alignment 
Range on Protein: 9-95
Range on HMM: 49-171/438.0
IIVRHGQ--------------------TEWSKSGQYTGLTDLP-------LTPYGEGQMLRTGESVFRNNQFLNPDNITYIFTSPRLRARQTVDLVLKPL
...|||                     . ...||..  |.|..       |||.|  |.   |.   .  ..|||....|...|.  |..|.   .|. |
vlfRHGaRtPtksklkkleplwellenattypsgplsflndwlgpcgagqLTplGreqayelGkrlrkrYglLnpedvlyvrssdvdRtlqSAqaflaGl

SDEQRA---------KIRVVVDD
 ...            | .... 
fppegtgelapilwqpipihtip
subfamily_PFKFB_pd Subfamily PFKFB 5-185 7.3e-10 30.6 In-house 5-158 (198) alignment 
Range on Protein: 5-185
Range on HMM: 5-158/198.0
TPRCI-IVRHGQTEWSKSGQYTGLTDlpLTPYGEGQMLRTGESVFrnNQFLNpdNItYIFTSPRLRARQTVDLVlkPLSDEQRAKirvvvdddLREWEYG
.||.| .||||..|. |.|. .| ..  ||. |. .  . .. .   .. |.  ..  ..|| . |. ||..|.   |..||. .        |.| . |
kpreiylvRhGeseknkkgriggdse..LterGveyakklakfik..eenlk..el.rvwtselkrtiqTaell..glpkeqwka........LdeldaG

DYEGMLTREIIELRKSRGLDKERPWNIWRdgCENGETTQQIGLRLSRAIAriqNLHRKHQSegrasdIMVFAHGHALRYFAA
...|.   || |   .    ...    .|    .||. ...  ||   |    .| |...       ... ||   ||   |
kcdgltyeeikekfpeefkerkkdkyryr..yprgEsyedlvqRlepvil...eLereqen......vliiaHqavlrvlla
subfamily_STS_pd Subfamily STS 29-204 1.3e-08 26.5 In-house 52-214 (245) alignment 
Range on Protein: 29-204
Range on HMM: 52-214/245.0
DLPLTPYGEGQMLRTGESVFRNNQflnpdNITYIFTSPRLRARQTVDLVLKPLSdeqrAKIRVVVDDDLREWEYGDYEG---MLTREIIELRKSRgLDKE
| |||  |  |   .|.  . ..      .| .|| || ||  ||.  .|| |      ||.. |.  | || . | .    .|. | ..  . .  |..
DpPlterGviqAkllgraLleagi.....kiehifcSPslrciqTaaailkglg....kkikikvepgllewlkldrkpipellspeelkkffpq.ided

R-PWNIWRDgCENGETTQQIGLRLSRAIARIQNLHrkhqseGRASDIMVFAHGHALRYFAAIWFGLGVQKKCETIEEIQN
  |     .  ...|.....  |  ...  | .         .  .|.. ||.  |        ||  ... .  . ...
Ykpvlslse.lkskeseeelyeRikkvvkeiiekv......pedgniliVahaatldalsrqllglspresedlkklvik
0053031 Phosphoglycerate mutase-like 8-92 2.5e-08 26.8 In-house 7-102 (342) alignment 
Range on Protein: 8-92
Range on HMM: 7-102/342.0
CIIVRHG----QTEWSKSGQYTGLTDLP---LTPYGEGQMLRTGESVFRN-NQFL----NPDNItYIFTSPRLRARQTVDLVLKPLSDEQRAKIRVV
 ..||||    .  . ..  ..  ....   |||.|  |.. .|.   .   ..|    ||| . |...|.  |..|.  ..|. | ...  .| ..
ivlvRHGaRtPlskgpldplnewfypcgageLTplGreqayelGrrlrkrYlgllpstynpdev.yvrssdvdRtlqSAqaflaGlfppegtpilnp
0048439 Phosphoglycerate mutase-like 9-131 3.3e-08 26.4 In-house 14-153 (391) alignment 
Range on Protein: 9-131
Range on HMM: 14-153/391.0
IIVRHG------------QTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFR---NNQFLN-----PDNITYIFTSPRLRARQTVDLVLKPLSDEQraK
...|||            .  . |   . .. . .|||.|  |.  .|.  ..   . ..|.       .. |...|.  |..|.   .|. | ...  .
vlfRHGaRtPtssypnkldpllnkllpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevyvrssdvdRtlqSAqaflaGlfppl..g

IRVVVDDDLREWEYGDYEGmLTREIIELRKSRGLDKERPWNIW
. |..  ...... . ..  ... .  |. .  || .. .. .
ltvilvivvesedpllnpl.pintcplledlllldalsalprf
0046349 Phosphoglycerate mutase-like 9-91 5.5e-08 25.5 In-house 12-113 (409) alignment 
Range on Protein: 9-91
Range on HMM: 12-113/409.0
IIVRHGQ------TEWSKSGQYTG----LTD-LPLTPYGEGQMLRTGESVFRN---NQFLNPD-----NITYIFTSPRLRARQTVDLVLKPLSDEQRAKI
...|||.      ... .. ...      ..  .|||.|  |. ..|.   .     ..|..      .. |...|.  |..|.   .|. | ...  .|
vlfRHGaRtPtkklsflpnwpginwtngpcgagqLTplGreqayelGkrlrkrYvdlgLlpsnslynpdeiyvrssdvdRtlqSAqaflaGlfpplggei

RV
  
vp
0049059 Phosphoglycerate mutase-like 9-92 2.7e-07 23.0 In-house 48-152 (435) alignment 
Range on Protein: 9-92
Range on HMM: 48-152/435.0
IIVRHGQ----------------------TEWSKSGQYTGLTDLP-----LTPYGEGQMLRTGESVFRNNQFLNPDNITYIFTSPRLRARQTVDLVLKPL
...|||                       | .. . ..   ...|     |||.|  |. ..|.   .  .||  ..  |...|.  |..|.   .|. |
vlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrYgfLynpdevyvrssdvdRtlqSaqaflaGl

SDEQrakirvV
 ...      .
fppe......i