Gene SpurPPP-Un-1 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP150_AA protein Get Run
SpurP150_AA_579-771 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPPLV_pd Subfamily PPPLV 582-770 1.2e-78 257.4 In-house 1-188 (290) alignment
Range on Protein: 582-770
Range on HMM: 1-188/290.0
CLLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCFEKALWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRP
.||.||  | ..||.| ||..|..|||.|||||||..||..||| |||.|. |||.|.||||||||||...||.||||...|.| | |....||||||. 
lllslcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnheles

VQKMFHFEAECTQKFGATIgQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSEGGVCSLAEINKIPVPLKDPENESQLAWELMWNDP
||. ... .|.. ||| .. ..||||.| .|||.|.|||.|.|.||.|.|.|..  . . .. |..|.  |||. . . ||....|.||
vqesieykgegsfkfgdsl.eevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdp

PP2Ac_SM00156 581-770 6.9e-53 172.4 In-house 4-180 (271) alignment
Range on Protein: 581-770
Range on HMM: 4-180/271.0
KCLLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCFEkalWRMGpLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELR
...|.|..|....| .|. |....|| .. ||.||...||. .     . |   .   ..|||||||||....||| .||. ||| |.|... ||||| .
eevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrll...elag.eppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEss

PVQKMFHFEAECTQKFgatiGQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNsegGVCSLAEINKIPVplKDPENESQLAWELMWNDP
.|.|.. || |. .|     |....| .. .|...|.||.||.||.| |||...    . || .|.|.     . . |..|...|.|.||
svnkiygfeeevkrky....gkeiyekfeeafsllPlaalvdskilcmhGGlsp...eleslddirklkr..vkekpeegllidllwsdp

0045823 Metallo-dependent phosphatases 580-770 8.2e-51 166.2 In-house 45-222 (473) alignment
Range on Protein: 580-770
Range on HMM: 45-222/473.0
AKCLLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCfekaLWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHEL
...|| |..||. .|..|| |..|.......||.||...||      | ..  .  .  ..||||.|||| ...||. .|.. ||..|...|..||||||
eedllklldeakeilkkepnllelsmrivviGDiHGqlddLlr....llekigfppedrlvflGDlvDrGpdslevlelllalkikypgnvfllrGNHEl

RPVQKMFHFEAECTQKFGATigqqVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSEggvCSLAEINKIPVPLKDPEneSQLAWELMWNDP
| .  .. |  |. .|.|.     ..|... .....|.|||...||...|||.. .     .| .|..|. ||  |.  ..|...|.|.||
rllnglygfgdetlekyged....lyeeflewlrslPlaaviggkilfvHGGlspdl...plldqireierpleipd..dgllldllwsdP

subfamily_PPP1C_pd Subfamily PPP1C 583-770 3.4e-49 160.5 In-house 15-189 (282) alignment
Range on Protein: 583-770
Range on HMM: 15-189/282.0
LLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCFEKAlwrmGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPV
. ||...|...| ..| |..|.||  |.||.||...||. . ..    .   .  ..||||||||||....|.|. |.. ||  |...|..|||||   .
ieallkkareillsqpilleleaPvkivgdihGqyadllrlfet....sgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhesasi

QKMFHFEAECTQKFGATigqqVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLKDPENesQLAWELMWNDP
.... |  || ......    .|.... .|. .|.||.||.||.| |||. ..   . || .|.||  ||. ||.   |. .|.| ||
nriyGfydeckrrysik....lWktftdvfnclPlaalvdekilcvhGGlspe...lksleqirkiqrPlevpek..gllcdllWsdp

PPP_3 583-747 3.5e-49 160.2 In-house 7-164 (271) alignment
Range on Protein: 583-747
Range on HMM: 7-164/271.0
LLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCFEKalwrMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPV
|  |.......| .|. |....||  ..||.|| ..||. ..|    .|      ..||||||||||....||. .|.. ||. |......||||| | .
lkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfk....nggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrqi

QKMFHFEAECTQKFGatiGQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSEGGVCSLAEINK
 |.. |. |...| |   |..|..... .|...|.||..|.|....|||. .|   . .. ....
nkvYgFkkevlkkkg...gkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikkler

0049330 Metallo-dependent phosphatases 582-771 6.5e-49 159.9 In-house 34-210 (309) alignment
Range on Protein: 582-771
Range on HMM: 34-210/309.0
CLLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCfekaLWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRP
 || |. .|...| .|| |..|...... ||.||...||      | ..  .  .  ..||||.|||| ...||. .|.. |.|.||..|..||||||| 
ellllllkakeilksepnllelsmrivviGDiHGqlddLlr....llekigfppedrlvflGDlvdrGpdslevlllllalkllypdnvfllrGNHElrl

VQKMFHFEAECTQKFGatigQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSEggvCSLAEINKIPVPLKDPENesQLAWELMWNDPL
.. ...|  |. .|.|    ...||... .....|.|||...||.|.|||....     .| .|...  ||  |.   .| ..|.|.|||
lnglygfgdetlrkyg....aelweefldwlrslplaaviggkilcvHgGlspdl...llldqirelerpleipld..gllcdllwsdpl

0053225 Metallo-dependent phosphatases 581-770 1e-46 152.9 In-house 25-202 (293) alignment
Range on Protein: 581-770
Range on HMM: 25-202/293.0
KCLLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLvcfeKALWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELR
. || |. ||...| .|| |..|....|..||.|||..||    .||...  .  .  ..||||.|||| ...||. .|.. |.|.||.....||||||.
eelllllleakeilkkepnllelsmriyviGDiHGnlddL....lallekigfppedrlvflGDlvdrGpdslevlelllalkllypdnvvllrGNHElm

PVQKMFHFEAECTQKFGatiGQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSEGgvcSLAEINKIPVPLKDPENesQLAWELMWNDP
 .. ...| .|. .|.|   ....|.... .....|.||....||...|||.. .     .| .|..|  ||  |..  .| ..|.|.||
llnglygfgdetlrkyg...aaelwdelldwlrslplaaliggkilfvHgGlspdls...lldqireinrplriple..gllldllwsdp

subfamily_PPP3C_pd Subfamily PPP3C 584-771 2.4e-45 148.2 In-house 47-221 (452) alignment
Range on Protein: 584-771
Range on HMM: 47-221/452.0
LALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVcfekALWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQ
| . .|| ..| .|. |....||  ..||.|| |.||.     |. .|   .  ..|||||||||| . .|.. ||.. ||  |...|..||||| | . 
lkiieeaakllkkektlleveaPitviGdihGqfydll....klfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecrhlt

KMFHFEAECTQKFGatigQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVpLKDPENESQLAwELMWNDPL
. | |. ||..|..    ..|..|.  .||..|.||..... .| |||.      . || .|.|.   .|.|..   |  .|.| |||
eyftfkeeckikys....eevydacmesfdslPlaallnqqflcvhGGlspe...ikslddikkldr.fkeppasGplc.dllWsdPl

PPP_1 583-736 5.2e-45 146.8 In-house 6-152 (264) alignment
Range on Protein: 583-736
Range on HMM: 6-152/264.0
LLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCfekaLWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPV
| .|.......| .|. |......  . ||.||.|.||.     | ..|      ..||||||||||.. ||.. .|.. |.  |...|..||||| | |
laelkkklkellnkeenllevseeitvcGDiHGqfdDLlk....lfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqv

QKMFHFEAECTqkfGATIGQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSE
 |.. |. |.      . ........  .|| .|.||..|.||.. |||. .. 
tkvygFkkEvl...kkkyskeiyktltdvFdvLplaalidekilivHGGlspel

subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 583-770 3e-43 141.0 In-house 29-204 (298) alignment
Range on Protein: 583-770
Range on HMM: 29-204/298.0
LLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVC-FEKALWrmgplLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRP
.  |...|. .... . |....||  . ||.||.. ||.  |.|| .          .||||||||||.. .|||  |.. |.  |..||..|||||   
veklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagf.....ppdanylflGdyvdrGrqnlevivlllaykvkypnnffllrGnhecea

VQKMFHFEAECTQKFGATIgqqVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLKDPENesQLAWELMWNDP
. ... |  ||....  .    .... .  |.|.|..|.. ..|.| |||. .    . || .....  | ...|.  .|| .|.| ||
inrvyGfyeeckrrykslr...lyaefqdvfnalpltaliggrilcmhGGlskk...lksldqlrelkrpfdskee..slaidllwadp

subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 571-770 3.3e-43 140.7 In-house 4-191 (287) alignment
Range on Protein: 571-770
Range on HMM: 4-191/287.0
WGTVEMLSLaKCLLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCFEKALWRMgpllTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKF
.|... .|  | .| . .... .|   | |....||  |.||.||...||. . .|  .     .   .|||||||||| . .||. .||| ||. | | 
ygvldafsd.kdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaa....pkvqylflGdyvdrGakslevslllfslkiaypkkv

FMIRGNHELRPVQKMFHFEAECTQKFGatigQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLKDPENESQLAWELMWNDP
 ..|||||.. . |.. |..| ..|..    .....  |  |. .|. | |...|.| |||. .    . || ... .. | .. . .  |  .|.| ||
hllrGnhevkkinklyGfkeelkrkrq....erlykqfndvfselplcarvskrilcmhGGispk...lksldslkalkkpttplacdeglqvdllwadp





PPP_2 609-744 2.7e-42 137.7 In-house 3-131 (198) alignment
Range on Protein: 609-744
Range on HMM: 3-131/198.0
ILGDLHGNFHDLVCFEKALwrmgPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQKMFHFEAECTQKFGatiGQQVWEAI
..|||||...||. . |         .  ..||||||||||....||. .|.. |.  |......||||| . |.|.. |. |...| |   |..|....
vcGDlHGqldDLlilfkng....lpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkg...gkkvykkl

NCCFDAMPIAAVVDNKIFCTHGGVPNSEGGVCSLAE
. .|...|.||..|.|....|||. ..   . .  .
qevfelLplaalidekvlvvHGGlseeiklldqikk

PPP_4 608-770 1.7e-41 135.5 In-house 2-155 (197) alignment
Range on Protein: 608-770
Range on HMM: 2-155/197.0
YILGDLHGNFHDLVC-FEKalwrMG-PLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQKMFHFEAECTQKfgatIGQQVW
.. ||.|| ..||.  . |    .|    .  |..|||||||||....||. .|.. |.  |......||||| . ..... |. |...|     |....
tvvGDiHGqlddlllkllk....ngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek....hgkeil

EAINCCFDAMPIAAVVDNKIFCTHGGVPNSEGGvcsLAEINKIPVPLKDPENESQLAWELMWNDP
.... .|| .|.||..|.|....|||....      |..|..|  . . | .|... . |.|.||
kklqdvfdllplaalidekvlvvhgglsdeles...ldkierierkiespleeekrkdlllwsdp

PPP_5_Dcr2 609-770 2.4e-41 134.9 In-house 3-156 (199) alignment
Range on Protein: 609-770
Range on HMM: 3-156/199.0
ILGDLHGNFHDL-VCFEKALwrmGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQKMFHFEAECTQKFgatIGQQVWEA
..||||| ..|| . ..|     |   .  ...|||||||||....||. .|.. |.. |......||||| . ..... |. |. .|.    |......
vcGDlHGqlddlllilfkeg...gdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlsky...hgkkiyki

INCCFDAMPIAAVVDNKIFCTHGGVPNSEGGVCSLAEINKipvPLKDPENESQLAWELMWNDP
.. .|| .|.||..|.|....|||....   . .|..|..   . . ||.. . |. |.|.||
lsdvfdwlPlaalidekvlvvhgglspeiksiellekier...kieipeekgekadlllwsdp

subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 583-771 3.5e-41 134.3 In-house 11-202 (302) alignment
Range on Protein: 583-771
Range on HMM: 11-202/302.0
LLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCF-------EKALWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRG
||.|...    | .|  |... .|  |.||.||.|.|||         |.|  ..    .   |.|||||||||.. .| |. .|. |.| | .. ..||
llllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyillrg

NHELRPVQKMFHFEAECTQKFGATIGQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLKDPENESqLAWELMWNDPL
||| . ..  . |. |  ...| . |...||  | .|  ||.||.| .||.| |||. .    . || .|.||  |||.  ..| || .|.. |||
nhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispk...lesledikkikrplkevteds.laqdllfadpl

subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 583-771 5.1e-41 133.8 In-house 12-203 (302) alignment
Range on Protein: 583-771
Range on HMM: 12-203/302.0
LLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCF-------EKALWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRG
||.|...    | .|  |... .|  |.||.||.|.|||         |.|  ..    .   |.|||||||||.. .| |. .|. |.| | .. ..||
llllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyillrg

NHELRPVQKMFHFEAECTQKFGATIGQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLKDPENESqLAWELMWNDPL
||| . ..  . |. |  ...| . |...||  | .|  ||.||.| .||.| |||. .    . || .|.||  |||.  ..| || .|.. |||
nhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispk...lesledikkikrplkevteds.laqdllfadpl

subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 581-770 1.4e-40 132.5 In-house 11-193 (284) alignment
Range on Protein: 581-770
Range on HMM: 11-193/284.0
KCLLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVC-FEKALWR-MGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHE
| |. ||  |. .. .|.  ....||  | ||.||.| ||.  ..   |  .        .|||||||||| . .|||. ||. |.| ||| |..|||||
kelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllrgnhe

LRPVQKMFHFEAECTQKFGATigqqVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNsegGVCSLAEINKIPVPLKDPEneSQLAWELMWNDP
 |||.. . | .|| ...  .    ..||.. .| |||..|||..||.| |||...   .. .| ...|.  |.  |.    .  .| | ||
srpvnmqygfyleckkrysea....lyeafqlafnamplcavvskkiicmhggise...dlldlkqldklerpidipd..igviadltwadp

subfamily_PPP4C_pd Subfamily PPP4C 584-770 7.6e-39 126.6 In-house 22-196 (288) alignment
Range on Protein: 584-770
Range on HMM: 22-196/288.0
LALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLvcfeKALWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQ
 |||..|. .| .|  . ....|  . ||.||.|.||    . |...|      ..|||||.|||| . || .  | . |.  ||.  .|||||| | . 
kalcakareilveesnvqrvdspvtvcgdihgqfydl....lelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqit

KMFHFEAECTQKFGATigqQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLKDPENeSQLAwELMWNDP
... |  || .|.|..   .||.     || ...||..|.|||| |||.  |   . .| ||  |    . |..  .|. .|.| ||
qvygfydeclrkygsa...nvwryctevfdylslaaiidgkifcvhgglsps...istldeirsidrkqevphe.gplc.dllwsdp

subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 583-770 4.2e-38 124.2 In-house 13-187 (281) alignment
Range on Protein: 583-770
Range on HMM: 13-187/281.0
LLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCFEKALWRmgplLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPV
. .. ||.. ....|  |.....|. ..||||..|.||    . | |    ..   ..||||||||| ...||.  ||. ||  .|. ...|||||.  |
ienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgr....vpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasv

QKMFHFEAECTQkfgaTIGQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLKDPENesQLAWELMWNDP
.|.. |  ||       .|...|  .. ||. .||.| ..... | |||.      . .| |. ..| |.....    |  .|.| ||
nkiygfyvecvt....kyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPe...ltaldelrnrpkpirnldr..GlviDllwadp

subfamily_PPP2C_pd Subfamily PPP2C 584-770 1.1e-37 122.8 In-house 23-197 (290) alignment
Range on Protein: 584-770
Range on HMM: 23-197/290.0
LALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVcfekALWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQ
 .|| .|. .|..|  . ....|  . ||.||.||||.     |...|       .|||||||||| . || ...| . |.  ...  ..||||| | . 
kelcekakeilskesnvqevkcpvtvcgdvhgqfhdll....elfkiggkspdtnylflgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqit

KMFHFEAECTQKFGATigqQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSEGGVCSLAEINKIpvplKDPENESQLAwELMWNDP
... |  || .|.|..   .||. .   || .|..|.||..||| |||.  |   .  . .....    ..  .|  |. .|.| ||
qvygfydeclrkygna...nvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrl....qevphegplc.dllwsdp

subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 589-770 3.1e-37 121.5 In-house 14-184 (284) alignment
Range on Protein: 589-770
Range on HMM: 14-184/284.0
EAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVC-FEKAlwrmgPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQKMFH
.|  .. ..| ||. |.|  | ||.||.| ||.  |.|       .   . .||||||||||.| .| |  ||. |.. |..|||.|||||   ..|.. 
hafsifnkqpmlievnspinicgdihgqfsdllrlfdkn.....gfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinkiyg

FEAECTQKFGAtigQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSEGGVCSLAEINKipvPLKDPENEsQLAWELMWNDP
|  || ...       |. ...  |  ||..|.| ..|.| |||| .    |  |  |..   |. .|| .  || ...| ||
fyeecqrrynk...psvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikr...pfdnpepn.tlaidilwsdp

subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 570-770 2.1e-36 118.5 In-house 9-197 (290) alignment
Range on Protein: 570-770
Range on HMM: 9-197/290.0
SWGTVEMLSLaKCLLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCFEKALWRMgPlltPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDK
 .|... .|  | .| . .... .|   | |....||  |.||.||.. .|. . .|. .  |      ||||||||||| . .||  .||  ||. . |
kygvldafsd.kdileilekieeileplpalleveapivivgdihgqldallryfdavgyp.p...kvkflflgdyvdrgakslevslllfcykiryskk

FFMIRGNHELRPVQKMFHFEAECTQKFGAtigqQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSEGGVCSLAEINKIPVPLkdpENESQLAWELMWND
  ..||||| | |.... |  | ..| |.    ..|   .  |. ... | |..||.| |||. .      ||  ..|  |||   . .  |  .|.| |
vhllrgnhevrkvnrlygfkeelarkrgs....rlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpl...tcdeglqvdllwad

P
|
p

subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 582-770 2.1e-36 118.7 In-house 28-204 (299) alignment
Range on Protein: 582-770
Range on HMM: 28-204/299.0
CLLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVC-FEKAlwRMGPlltPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELR
 |  ||. |..|.|... |....||  . ||.||.. ||.  |.||  .. |      |||||||||||   .|.|. |.  ||  |..|||.|||||  
elqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdka..gfpp...dvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhecp

PVQKMFHFEAECTQKFGATigqQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPlKDPENESqLAWELMWNDP
 ..... |  || ... .|   ..| ... .|.|||.. .. ..|.| |||.      . .|  . ... | .|| | | |  .|.| ||
ainrvygfyeecnkrykst...rlwsifqdafaampltgligsrilcmhgglspk...lqtldqlrdltrp.qdppnps.lgidllwadp

subfamily_PPP5C_pd Subfamily PPP5C 581-770 1.7e-35 115.6 In-house 37-219 (322) alignment
Range on Protein: 581-770
Range on HMM: 37-219/322.0
KCLLALCREAQRVLANEPRLIKLNAPT----YILGDLHGNFHDLVC-FEKalwrMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRG
|. |..  ||...| ..| |.... ..     . ||.||.|.||.  ||.     |   .  ..|| ||.|||| . ||||  |.. |.| |..||. ||
kyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifel....nGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrG

NHELRPVQKMFHFEAECTQKFGatigQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSEGgvCSLAEINKIPVPLKDPENESqlAWELMWNDP
|||   . |.. || |...|.     ..| .  .  |. .|.| |...|..  |||.....|   .| .. ||    ..||..     ||.| ||
nhesdnmnklyGfegevkakyt....ekvadlftevfnwlPlahvinekvlvvhGGlfsedg..vtlddlrkidrnaqppeegl..lvellwsdp

subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 600-770 2.5e-35 115.4 In-house 2-165 (263) alignment
Range on Protein: 600-770
Range on HMM: 2-165/263.0
LIKLNAPTYILGDLHGNFHDLVCFEKALwrmgPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQKMFHFEAECTQKFGA-
|..|.||  | || ||.. ||.   .|        |   .|||||||||| | .|||  ||| |.  | |....||||||. ..| . | ||  ..|   
llelqapinicgdthgqyndllrifnac....gaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqre

TIGQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLKDPEnESQLAWELMWNDP
 . . |.. .|  |  ||..|.| ..|.| |||.      . || .|  ||.||.  .    || .|.| ||
evyesvynhfnqvfsymplcaivskrilcmhggisph...lkslddiraiplpletak.thplacdllwadp

subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 586-770 3e-35 114.7 In-house 14-185 (280) alignment
Range on Protein: 586-770
Range on HMM: 14-185/280.0
LCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCF-EKAlwrmgPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQK
. .. ...|. .  .....||  . |||||.. ||. . ...      .     .||||||||||.. .|||  |.. |.  |..|...|||||   ...
viekckkiltaqatmvevdapvavcgdlhgqytdllrlfarv.....sfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevisinr

MFHFEAECTQKfgatIGQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLkDPENESqLAWELMWNDP
 . |  |. ..      ..... ..  .| .|..|.|  .|.| |||. .    . || .....  |. |.|.|. || .|.| ||
kygfkdevkrr....yslalynefqelldslplvalvsgrilcmhgglsqk...lvslddlaelrrpf.dsedec.lamdllwadp

subfamily_PPG1_pd Subfamily PPG1 583-770 2.6e-34 111.8 In-house 19-195 (300) alignment
Range on Protein: 583-770
Range on HMM: 19-195/300.0
LLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVcfekALWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPV
. .|.   . .| .|  .|....|  ..||.||.|.|..     ....|  .    .|||||||||| . || |. |   |.  | .  ..||||| | .
vkeltdklkellvkesnvieirspvtvvgdvhgqfydvl....eifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgnhesrqi

QKMFHFEAECTQKFGATigQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEInKIPVPLKDPENESQLAwELMWNDP
 ... | .|| .|.|    ..||. .   || . .||..|..|.| |||.  |   | |. .| |.   ...  ||  || .|.| ||
tqvygfyteclrkyggn..srvwkylteifdylvlaaiideeiycvhgglsps...vlsidqi.kvldrfrevpnegala.dllwsdp

subfamily_PPZ_pd Subfamily PPZ 583-770 1.4e-33 109.7 In-house 30-204 (300) alignment
Range on Protein: 583-770
Range on HMM: 30-204/300.0
LLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVC-FEKAlwrmGpLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRP
.| .| .|. .. ..| |..|. .  |.||.||.. ||.  | |.    | .   . .||||||||||.. .| |  |.  ||  |..||..|||||   
ilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkc....g.fppsanylflgdyvdrgkqsletillllcykikypenffllrgnhecan

VQKMFHFEAECTQKFGAtigqQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLKDPEneSQLAWELMWNDP
| ... |  || ..       ..|...   |...|.||.|  |||| |||.      . |. || ..  |   |.    |  .|.|.||
vtrvygfydeckrrcni....kiwktfvdtfntlplaaivagkifcvhgglspv...lnsmdeirhvvrptdvpd..fglindllwsdp

subfamily_PPP6C_pd Subfamily PPP6C 583-770 2.4e-33 108.5 In-house 20-195 (290) alignment
Range on Protein: 583-770
Range on HMM: 20-195/290.0
LLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLvcfeKALWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPV
| .||   . .| .|  .  ...|  . ||.||.|.||    . |.| |  .   |..||||.|||| . .| ...|.. |.  ||.  ..||||| | .
lkklcdlvldllleesnvqpvsspvtvcgdihgqfydl....eelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqi

QKMFHFEAECTQKFGATigqQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLKDPEnESQLAwELMWNDP
 ... |  ||..|.| .   ..|  .   || ..|||..|....| |||.      |  | .|. |    . |. .  .. .|.| ||
tqvygfydeclnkygna...nawkyctkvfdlltiaaiideqvlcvhGglspd...vktldqirvieraqeiph.kgafc.dlvwsdp

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 638-770 3e-32 105.1 In-house 102-225 (317) alignment
Range on Protein: 638-770
Range on HMM: 102-225/317.0
SFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQKMFHFEAECTQKFGAtigqQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeg
 .|||||||||| . .||.  ||. |.| ||| |..||||| ||| . . |  |..... |    ...|| .  | ..|..|||..||.| |||....  
kylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysa....alyeafqlafnvlplcavvnkkilcmhGGisee..

gVCSLAEINKIPVPLKDPEneSQLAWELMWNDP
 . .| ...|.  ||. |.    .  .| | ||
.lldlkqldklkrpldipd..vGvladltwadp

subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 587-770 3.5e-31 101.5 In-house 29-202 (307) alignment
Range on Protein: 587-770
Range on HMM: 29-202/307.0
CREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCFEKALWRmgPllTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQKMF
  ||| ... |  |. .. |  ..|||||.| ||. .   | |  |      ..| |||||||   .|.|  ||. ||  |..  ..|||||.  |.| .
iyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgr..p..petvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnkky

HFEAECTQKFgATIGQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLKDPENesQLAWELMWNDP
 |  ||        |...|  .. ||. .||.|..  ||.| |||.  .   .  | |. . | |...|     .  ...| ||
gfyeecvtsi.pkcgeeiwalfqrcfnnlpisaliatkilcmhgglspa...ltcldelrnhpkpirnpfr..givndmlwadp

subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 583-770 3.7e-31 101.6 In-house 11-185 (280) alignment
Range on Protein: 583-770
Range on HMM: 11-185/280.0
LLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVCFEKALWRMgpllTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPV
..|. |  . .. .|  |.. .||  ..||.| ...|.  .   . |.        ..||||||||| .|.||.  ||  ||   |. ...|||||   |
iiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrv....peeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsv

QKMFHFEAECTQKFGatIGqqVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSeggVCSLAEINKIPVPLKdPENeSQLAWELMWNDP
.|.. |  ||  |.|  .|  .|  ...||. ||..... ....| |||.      .  |  | .|| | . | .   |  .|.|.||
nkiygfyvecqykyg..vg..lwwdfqscfnrmpmsgliskrvlcmhgglspe...linldtirniprpce.pld.rgllidllwsdp

subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 584-771 2.5e-30 98.8 In-house 29-206 (297) alignment
Range on Protein: 584-771
Range on HMM: 29-206/297.0
LALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVcfekALWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQ
| |   |  |. ..  ....|||  . ||.||.| ||.     |.. |     . .||||||||||   .| |  |.. |.  | ..|..|||||   |.
lklldlaldvfkaqksmvevnapikvcgdihgqfpdll....rlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhecefvn

KMFHFEAECTQKFGATigqQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSEGGVCSLAEINKIPVPLkdpENESQLAWELMWNDPL
|.. |  || ... .    ... |..  |. .|.. .. .||.| |||.        .|  ..||  .    | . .|  .|.| ||.
kvygfyeecqkryqsv...rmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkierst...egkerlvadllwadpi

subfamily_PPP7C_pd Subfamily PPP7C 580-735 1.3e-26 86.2 In-house 35-190 (383) alignment
Range on Protein: 580-735
Range on HMM: 35-190/383.0
AKCLLALCREAQRVLANEPRLIKLNAP----TYILGDLHGNFHDLVCFekaLWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRG
|| .| . |||..|| . | . ....       . |||||.. ||.     |.. |   .  ...| ||.||||...||..  |..  .. | .... ||
akyvllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddllli...lyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrG

NHELRPVQKMFHFEAECTQKFGAtIGQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNS
|||   .   . |  | ..|.    |... . ..  |  .|.|...|.||.  |||. ..
nhedhilnlryGfikeveskykv.hgkkilrlledvfawlplatlidekilivhGGisdk

Metallophos Calcineurin-like phosphoesterase 607-740 7.5e-25 81.4 Pfam-A 3-168 (200) alignment
Range on Protein: 607-740
Range on HMM: 3-168/200.0
TYILGDLHGNFHDL-VcFEKALWRMGPLLTPCSFLFLGDYVDRGEHGVEVIAYL--FSQKILAPDKFFMIRGNHELRPVQKMFHFEAECTQ---------
  ..|||||...||   .. .| ...    |  .|||||.|||| .. |..|.|  ...|.|.|...|..||||| .|. . . |  |.           
ilvigDlHgglddled.lllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange

---------------------KFGATIGQQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSEGGVC
                      ..   |  ..|... .|.|.|..| ||.||..|||..  |.| ..
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgd

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 639-770 2.2e-21 69.4 In-house 122-244 (339) alignment
Range on Protein: 639-770
Range on HMM: 122-244/339.0
FLFLGDYVDRGEHGVEVIAYLFSQKILAPDKFFMIRGNHELRPVQKMFHFEAECTQKFGAtigqQVWEAINCCFDAMPIAAVVDNKIFCTHGGVPNSegg
.||||||||||   .||.  | . |.  ||. ...||||| | |.  . |  |   .. |    |..|...  |. .|..||..| |.| |||. .    
ylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyryda....qlyecfqnmfnvfpfcavinntimcmhggiseh...

VCSLAEINKIPVPLKDPENesQLAWELMWNDP
. |. ..  .  ||. |.    .  .| | ||
ltsfnqfsvfkrpleipdv..gvltdltwadp

EF-hand_7 EF-hand domain pair 243-326 2.6e-09 27.0 Pfam-A 6-65 (66) alignment
Range on Protein: 243-326
Range on HMM: 6-65/66.0
FRSFDSKRQGYLDPEDFINCPMTLAFDSKrqgyldpedfinglaamqpsapHGGLPAelRCRYIFRYYDQNRHGKMEFTGFKQM
|...|. . ||||.|.. .    |  . .                      .....    ..|||...| |. |.. |. | |.
FkllDkdgdgyldkeeLlrllkhlgspli......................deevre..vldyifkeiDkngdGvlsfeEflqa

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 578-622 2.4e-07 23.1 In-house 11-55 (339) alignment
Range on Protein: 578-622
Range on HMM: 11-55/339.0
SLAKCLLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVC
  |  |  ||. |. ..  || ..||.||  ..||.||.| ||..
fcaaelaelchrareliwsepiflkleapicvmgdihgqfddlla

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 577-622 6.3e-07 21.8 In-house 8-53 (317) alignment
Range on Protein: 577-622
Range on HMM: 8-53/317.0
LSLAKCLLALCREAQRVLANEPRLIKLNAPTYILGDLHGNFHDLVC
|  .| |. ||  |. .. .||  ..|.||  |.||.||.|.||. 
lfkekelielcyrarelfwkeplkleleapvtivGdihGqfedlla

PDZ_1 PDZ-like domain 48-99 2.7e-06 13.8 Pfam-A 4-57 (78) alignment
Range on Protein: 48-99
Range on HMM: 4-57/78.0
SASFVKTAGALLQDLPVQATLESVLKVTFSVVNKPDFQRELRK--KRIFVISLL
  .||. ||| ..||. |. .   ..|   .|...  . .| .  |. ..|. .
pdrfvevaGatfhdLsyqqaRsyaipvkgvyvseasgsfslaskekkgviitsi