Gene PPP6C-2 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP6C
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP162_AA protein Get Run
SpurP162_AA_3-293 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPP6C_pd Subfamily PPP6C 6-294 5.2e-181 593.1 In-house 1-289 (290) alignment
Range on Protein: 6-294
Range on HMM: 1-289/290.0
NLDRWIEIAKXCKYLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFP
.||.|||.|| |||||||||||||||| ||.|||.||||||.||||||||||||||||||||||||.|||||. .|| ||||||| ||||||||||||.|
eldkwielakkckylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakyp

DRIVLXRGNHESXQITQVYGFYDECQTKYGNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDNVET
|||.| |||||| ||||||||||||..||||||||.||||||||||||||||||||||||||||||||. || .|||||||||||||||||||||..|||
dritllrgnhesrqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdpedvet

WAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDATTREAKLFRNVPDSER
||.||||||.||| |||. ||| ||||||| |||||.||.|||||.|||||||||||||||||.|||||..||..||||||..|||.||
wavsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereaklfkavpdeer

subfamily_PPP4C_pd Subfamily PPP4C 6-290 7.3e-139 454.9 In-house 2-286 (288) alignment
Range on Protein: 6-290
Range on HMM: 2-286/288.0
NLDRWIEIAKXCKYLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFP
.||| ||  . |. . |...|.||  . .. .||.||| | .||||||||||||||| |||. ||..|.|.|. .|| ||||.|| |||  ||.||...|
dldrqieklrrcelikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvryp

DRIVLXRGNHESXQITQVYGFYDECQTKYGNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDNVET
|||.| |||||| ||||||||||||  |||.|| |||||.|||.|..|||||....||||||||...|. .| .|.| ||.||.|..|||.||||...|.
dritlirgnhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaeg

WAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDATTREAKLFRNVP
||.||||||.||| .|.. |.. |...||| |||||.||||..|..|..||||||||||||||.|.|| ..... .. |.| ...
wavsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaaa

subfamily_PPP2C_pd Subfamily PPP2C 5-288 4e-129 422.9 In-house 2-285 (290) alignment
Range on Protein: 5-288
Range on HMM: 2-285/290.0
SNLDRWIEIAKXCKYLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKF
..||..||  | || | |...|.||. . ..  .| |||.|..|||||||.||||.|| |||. ||. ||| |. .|| ||||||| || | | .|| ..
kdldklieklkeckqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvry

PDRIVLXRGNHESXQITQVYGFYDECQTKYGNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDNVE
..||.. |||||| ||||||||||||  |||||| |.| |..|| |...|..|||..|.|||||| ..|. .|  ..| ||.||.|..|||.|||||. .
keritilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpddrg

TWAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDATTREAKLFRN
 |.|||||||. || .... | . |.|.||  ||||| |||....| ..||..||||||||||| |.|| ..|. ...   |  
gwgisprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdp

subfamily_PPG1_pd Subfamily PPG1 7-292 8.4e-114 372.9 In-house 1-299 (300) alignment
Range on Protein: 7-292
Range on HMM: 1-299/300.0
LDRWIEIAKXCKYLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPD
||. .|  . .. |||  .|.|.| . .| ..| ||. . .|||| ||.||||||. |.|. |||.||| |. .|| ||||.|| || . |..|| ..| 
ldecleklqkaellpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklryps

RIVLXRGNHESXQITQVYGFYDECQTKY-GNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPD----
|| | |||||| ||||||||| ||  || ||.. |.| |..|| |..||||||.. ||||||||.|..| || ...| .|.|..||..||.||||.    
ritllrgnhesrqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennn

------NVE--TWAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDATTREAKLFRNVPDS
      . |   . .|.||||. .| .|.. |.. |... |  ||||..|||. .||.|| |||||||||||||| ||||  ..   |  . . . |.|
ptldhpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnvyeeapes

PPP_3 20-286 3.1e-107 350.6 In-house 2-269 (271) alignment
Range on Protein: 20-286
Range on HMM: 2-269/271.0
LPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQ
|.||.||.|.. . ..  .| |.. .|.|||||||||||..|| |||..||..|.|.|. .|| ||||..| |... ||.|| |.|....| |||||| |
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq

ITQVYGFYDECQTKYGNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDL-VWSDPDNVETWAISPRGAGWLFG
|..||||..|...|.|... ......||.||..||.|||.||.|||||||..|.. ||  .|| .|.|..|...|| ..|||.. |... |.||||.|||
inkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFg

XKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDATTREAKLF
 .||. |.. |.||||. ||.|..|||....| |.|||.||||||.|..| ..|| ...|.|.| |..
pdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkql

0045823 Metallo-dependent phosphatases 4-293 6e-106 347.8 In-house 27-328 (473) alignment
Range on Protein: 4-293
Range on HMM: 27-328/473.0
XSNLDRWIEIAKXCKYLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAK
 ..||..||. | ...|||.||.||.| . ..  .| |....| ...|.||||||..||..|..  | .|.. .. .|| ||||..| |.. .|| || |
lldldlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkik

FPDRIVLXRGNHESXQITQVYGFYDECQTKYgNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDNV
.|....| |||||. .....|||.||.  || ... .... .... | .||.|....|.||||||||.... || .||| .|||. |...||.||||...
ypgnvfllrGNHElrllnglygfgdetleky.gedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdPwed

ET--------WAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDK------LVTVWSAPNYCYRCGNIASILAFNDATtREAKLFRNV
.         .  ||||||.||| .... | . |.|.||. .|. |.|||...||.|      ..||.||||||.|.|| |..| ... . .. ..|. .
dgdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdps

PDSE
|.  
phpl

0049330 Metallo-dependent phosphatases 5-293 1.6e-101 332.4 In-house 15-303 (309) alignment
Range on Protein: 5-293
Range on HMM: 15-303/309.0
SNLDRWIEIAKXCKYLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKF
|.||..||. . .|.|.|..|..|.. . .. ..| |....| ...|.||||||..||..|..  | .|.. .. .|| ||||..| |....|| || ..
slldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalklly

PDRIVLXRGNHESXQITQVYGFYDECQTKYGnANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPD-NV
||...| |||||. .....|||.||.. ||| |. |........ | .||.|....||||||||||.... || ..|| .|||. | .|||.||||.  .
pdnvfllrGNHElrllnglygfgdetlrkyg.aelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpir

ETWAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDATTREAKLFRNVPDSE
|..| .|||.|..||  ... |.. |.|.||. .|..|..||...||.||.||.||||||.|.|| ...| ... .... .||. ||   
egfapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvplll

PPP_1 22-273 7.5e-101 329.8 In-house 3-262 (264) alignment
Range on Protein: 22-273
Range on HMM: 3-262/264.0
ENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQIT
|. |..|.. . .|  .| |.. ||...||||||||||.|| .||..||. |.|.|. .|| ||||..| |... ||.|| |.|... | |||||| |.|
eeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqvt

QVYGFYDECQTKYGNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDL--------VWSDPDNVETWAISPRGA
.||||..|...|..... ....|.|||.|..||.|||..|.|||||||..... ||  ..| .|.|..|..|||        ...|... |..| |.|||
kvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRGa

GWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASIL
|.||| .||. |.. ||||||. ||....|||......|.||..||.||.....| ....
gylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayv

0053225 Metallo-dependent phosphatases 5-290 3e-98 321.7 In-house 7-292 (293) alignment
Range on Protein: 5-290
Range on HMM: 7-292/293.0
SNLDRWIEIAKXCKYLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKF
..||..||. . .|.|.|..|..|.... .. ..| |....| ...|.|||||...||..|..  | .|.. .. .|| ||||..| |....|| ||...
llldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalklly

PDRIVLXRGNHESXQITQVYGFYDECQTKYGNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDNVE
||..|| |||||. .....|||.||.  |||.|. |........ | .||.|....|.||||||||. .. || .|.| ..||. |...||.||||| ..
pdnvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpdlws

TWAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDATTREAKLFRNVP
.|..|.||.|..||  ..  |.. |.|.||. .||.|..||...||.|||||.|||||..|.|| ...||... .... |||. |.
gwlpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfapvl

PP2Ac_SM00156 21-288 7.8e-94 306.7 In-house 2-269 (271) alignment
Range on Protein: 21-288
Range on HMM: 2-269/271.0
PENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQI
 ......|.. | ..  .| |.  ||.||||.||||||..|| .|....|. |.. |. .|| ||||..| |. . |..|| ..|...|| |||||| ..
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssv

TQVYGFYDECQTKYgNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDP-DNVETWAISPRGAGWLFGX
...|||..|.. || .....  ....|.||..||..|...||.||||||..... .|  ..|..|.|..| ..||.|||| ........| ||.. .|| 
nkiygfeeevkrky.gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFge

KVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDATTREAKLFRN
.... |.. ||||||. ||..|.|||....| ||||..||||||....| |..| ...... .......
davkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlke

subfamily_PPP1C_pd Subfamily PPP1C 20-287 1.4e-91 299.6 In-house 10-277 (282) alignment
Range on Protein: 20-287
Range on HMM: 10-277/282.0
LPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQ
| |.....|..   .. |..  .  .. ||...||||||..||  || |.|  |...|. .|| ||||  | || . ||..| |.|... | |||||| .
lkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhesas

ITQVYGFYDECQTKYGNAnAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDN-VETWAISPRGAGWLFG
|...|||||||...|..   |.  |.||. | .||..||..|||||||||..| . ||  |.|  |.|.||  |||.|||||. |..|. . ||  . ||
inriyGfydeckrrysik.lWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendrGvsftfg

XKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDATTREAKLFR
 .| . |.. |.|.||. |||.|..||... . .||||.|||||| . .| ...|. ..  . . ....
kdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilk

subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 14-279 5e-79 258.4 In-house 18-284 (298) alignment
Range on Protein: 14-279
Range on HMM: 18-284/298.0
AKXCKYLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRG
.| .| . |.|..||..|. ..  .   .  | .|..||||||||. ||  ||  .|  ||. |. .|| |||| .. |. . ||. |.|.|....| ||
kkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnffllrG

NHESXQITQVYGFYDECQTKYGNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDN-VETWAISPRG
|||  .| .|||||.||. .| . . .    .||. | ..|.| ...||.|||||. .|.. |.  ..|... ...    ||.|.||.| |. || . ||
nheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadpenavkgwaensrG

AGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDAT
..  || .| . ...  .. |.. |||.||.||... . ||||..|||.|| .  | |...  ..  
vsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdekl

PPP_2 49-240 8.8e-74 240.5 In-house 1-197 (198) alignment
Range on Protein: 49-240
Range on HMM: 1-197/198.0
VTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQTKYGNANAWRYCTKVFD
||||||.|||..|| .||..|...|...|. .|| ||||..| |... ||.|| ..|....| |||||| ....||||..|...|.|..........||.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe

LLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDL-----VWSDPDNVETWAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQL
||..||.|||.||.||||||...|.. ||  .|| .|.|..|...||     ....... |..| | ||||.||| .||. ... |.||||. ||..
lLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev

subfamily_PPP3C_pd Subfamily PPP3C 22-278 3.7e-73 239.8 In-house 43-312 (452) alignment
Range on Protein: 22-278
Range on HMM: 43-312/452.0
ENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQIT
|..  |. . . .|  .| ..  |..|.||.|||||||||| .||  ||.  .|.|. .|| |||||.| |.   |..|| ..|... | |||||.  .|
eeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecrhlt

QVYGFYDECQTKYGNaNAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDN----V---ET-WAISPRGA
. . | .||..||.. . .  |.. || | .||....| |||||||||..|.. .|  ..| .|.|..|..|||.|||| .        |.    |.|| 
eyftfkeeckikyse.evydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfvpnsvrGc

GWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFD------DKLVTVWSAPNYCYRCGNIASILAFNDA
 .... | .  |.. |.|  |  ||.  ..||.   .        |.|..|||||.    | |..| ... 
syfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyenn

subfamily_PPP5C_pd Subfamily PPP5C 45-290 8.1e-72 234.9 In-house 63-310 (322) alignment
Range on Protein: 45-290
Range on HMM: 63-310/322.0
VSTPVTVCGDIHGQFYDLEELFRTGGQI-PDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQTKYGNaNAWRYC
 .. .||||||||||||| ..|.  |.  .. .|.  || |||| .| |.   ||..|  .|... | |||||| .. ..||| .|...|| . .     
etkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrGnhesdnmnklyGfegevkakyte.kvadlf

TKVFDLLTIAAIIDEQVLCVHGGL-SPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDNVETWAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQ
|.||. | .| .|.|.|| ||||| | |  |. ..  |.| .. |..|....|.||||.. .  . | || |  ||  ||. |.. |||.||  .|.. .
tevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqeanGrspskrGvgvqfGpdvtkkflkennleliirshevke

EGYKYMFDDKLVTVWSAPNYCYRCGNIASILAF-NDATTREAKLFRNVP
|||. . | ||.||.|||||| . || .... . .| .. . | |  |.
eGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfeave

subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 18-290 1.2e-70 231.1 In-house 22-295 (299) alignment
Range on Protein: 18-290
Range on HMM: 22-295/299.0
KYLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHES
| . |..|..||..  .  .... .  | .|. ||||||||. ||  .|   |  ||. .. .|| ||||    |. | ||  | |.|.|. . ||||| 
ksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhec

XQITQVYGFYDECQTKYGNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDN-VETWAISPRGAGWL
  | .|||||.||. .|  .  |    . |. . .. .|  ..||.|||||| ..|. |.  . | |. |      ||.|.|||. |  |    ||  ..
painrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqsvkdwlanvrgvsyv

FGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDATTREAKLFRNVP
|| .| .  ..  .. |.. |||.||.||... . ||||..||| || .  | |.|.  ..      ....  |
fgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptp

PPP_4 49-240 5.9e-70 228.3 In-house 1-196 (197) alignment
Range on Protein: 49-240
Range on HMM: 1-196/197.0
VTVCGDIHGQFYDL-EELFRTGGQIP-DTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQTKyGNANAWRYCTKV
|||.||||||..||  .|...||. . ..||. .|| ||||..| |... || || ..|...|| |||||| .....|||..|...|  ..........|
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek.hgkeilkklqdv

FDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIP-HKGAFCDLV-WSDPD-NVETWAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQL
||||..||.|||.||.||||||...... .|  |||..|.| ......||  ||||  . |..| | ||||.||| .||. |.. ||||||. .|.|
fdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel

subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 19-281 8.9e-70 228.3 In-house 7-275 (284) alignment
Range on Protein: 19-281
Range on HMM: 7-275/284.0
YLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQI------PDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXR
 | |..| .||    .|  .|   . . .||...||||||| ||  |.   |         .. |. .|| |||| .| |  | |...| ..||...| |
llkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllr

GNHESXQITQVYGFYDECQTKYGNAnAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPD-NVETWAISPR
|||||  . . |||| ||. .| .|  .      |  . ..|.......|.|||.| |.  . |.  .||  .||  |  .||.|.||. .||... |||
gnhesrpvnmqygfyleckkrysea.lyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegykespr

GAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDATTR
||| .|| |  . |..  .|.|.  |||.|..||... | ||||..||| || .  |||..|  ..    
gagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelva

subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 23-292 4.1e-69 225.9 In-house 11-278 (281) alignment
Range on Protein: 23-292
Range on HMM: 11-278/281.0
NDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQ
......   |  .  || ..  . .|..| ||.|.|| ||..||   |..|.. .. .|| ||||  | |..  |.||| ...||||| |||||  .. .
eeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasvnk

VYGFYDECQTKYGNaNAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDN-VETWAISPRGAGWLFGXKV
.|||| ||.||||  . |    . |. | |.| |...|||.||||||.. .. ..  . .  . ...|   ||.|.|||| || |  | ||....|| .|
iygfyvecvtkyGe.elwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssftfGknv

TNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDATtrEAKLFRNVPDS
 .      .. ||  |||.||.||. .   ||.||.|.||||    | |..|  ...   . .| . ||.|
vddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetl..gislvalvpas

PPP_5_Dcr2 49-240 5.9e-69 225.0 In-house 1-198 (199) alignment
Range on Protein: 49-240
Range on HMM: 1-198/199.0
VTVCGDIHGQFYDL-EELFRTGGQIP-DTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQTKYGNANAWRYCTKV
||||||.|||..||  .||..||. . ...|. .|| ||||..| |... || || ..|....| |||||. |....|||..|...||...........|
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv

FDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIP-HKGAFCDLV-WSDPD-NVET-WAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQL
|| |..||.|||.||.|||||||..|.| ..  |||..||| .||  .||. ||||  ..|. .. | ||||.||| .||. |.. ||||||. .|.|
fdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshel

subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 21-276 6.2e-67 218.7 In-house 7-262 (280) alignment
Range on Protein: 21-276
Range on HMM: 7-262/280.0
PENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQI
 | |.... . . .. . .  .  | .||.||||.|||. ||  ||   .  ||. |. .|| |||| .  |    ||. |...|..... |||||  .|
keadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevisi

TQVYGFYDECQTKYGNAnAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPD-NVETWAISPRGAGWLFGX
 . |||.||.. .| .|  .    ...| | ..|..  ..||.|||||...... ..  . |  . ...    ||.|.||. .|  || ..||.  .|| 
nrkygfkdevkrrysla.lynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvsvifga

KVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFN
.| . ...  .. ||.  ||.||.||... | |||||.|||.|.    | |..|  .
nvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivd

subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 16-277 2.4e-64 210.5 In-house 19-283 (297) alignment
Range on Protein: 16-277
Range on HMM: 19-283/297.0
XCKYLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNH
 .| . |. . || ||  |.   . ..  | .|. ||||||||| ||  ||. ||  | . |. .|| |||| .| ||   ||. | |||  ..| ||||
lskviteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnh

ESXQITQVYGFYDECQTKYGNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSP---DVKTIXQIXMIERAQEIpHKGAFCDLVWSDPD-NVETWAISPR
|   . .|||||.||| .|     .     ||. | .. .| ...||.||||||   .  |.  .  |||..|  ...  .||.|.||   .  .    |
ecefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisglsgfmenqr

GAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFND
|||  ||       .   .| |.| |||.||.||...   ||||..||| || .  | |.... ..
gagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscde

subfamily_PPZ_pd Subfamily PPZ 20-277 9.1e-63 205.5 In-house 25-282 (300) alignment
Range on Protein: 20-277
Range on HMM: 25-282/300.0
LPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQ
| .... ..|    .| | . ..  .| .| . ||.|||. ||  ||   |  | . |. .|| ||||  | ||   ||  | |.|. ..| |||||  .
lknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffllrgnhecan

ITQVYGFYDECQTKyGNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDP-DNVETWAISPRGAGWLFG
.|.||||||||. .  | . |.     |. | .|||.  ...|||||||| .... .|  . |  ..|  |   ||.|||| |. . |    ||  . . 
vtrvygfydeckrr.cnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptdssnewednergvsycyn

XKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFND
    | |.    . |.| || .|..||... |  ||||.||||||    |  .... ..
kvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvse

subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 18-277 2.5e-62 203.8 In-house 4-263 (280) alignment
Range on Protein: 18-277
Range on HMM: 4-263/280.0
KYLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHES
. .   ..  .  .|  . .||.|.    .|. | |||| |. |.. ||   |..|.   . .|| ||||    | .  |. || .. ||| | |||||.
nvmtgheiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhet

XQITQVYGFYDECQTKYGNANAWRYCTkVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDN-VETWAISPRGAGWL
  . ..|||| ||| ||| .  | . . .|. . ....| ..|||.||||||..  .  |  | |  |   .| . ||.|||| |  | |  | ||  ..
psvnkiygfyvecqykygvglwwdfqs.cfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisym

FGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFND
||  | .  ..  .. ||  |||.||.||. |   .|.||.| |||| .  | |.....| 
fgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclna

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 75-287 2.8e-62 203.7 In-house 101-313 (317) alignment
Range on Protein: 75-287
Range on HMM: 101-313/317.0
TSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQTKYGNaNAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTI
  |. .|| |||| .| |  . |..|| ..||...| ||||||  . . |||| |.. .| . . .    ..|  | ..|......||.|||.| ..  .
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysa.alyeafqlafnvlplcavvnkkilcmhGGiseelldl

XQIXMIERAQEIPHKGAFCDLVWSDPDN-VETWAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASIL
 |.  ..|  .||  |  .||.|.|||. |.... |.|||| .|| |  . |..  .|.|.  |||.|..||... | ||||..|||.|| .  |||..|
kqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavl

AFNDATTREAKLFR
  ..  .   ...|
svdkklkisinvlr

subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 44-278 1.2e-61 201.1 In-house 34-271 (287) alignment
Range on Protein: 44-278
Range on HMM: 34-271/287.0
PVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQTKYGnANAWRYC
 | .|.|..||||||. ||  .|   |. |.. |. .|| ||||  | |    |..|| ..| .. | |||||  .| ..|||..| . |..  . ..  
eveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhevkkinklyGfkeelkrkrq.erlykqf

TKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEI--PHKGAFCDLVWSDPDN-VETWAIS-PRGAGWLFGXKVTNXFVHXNNLKLICXAHQ
 .||. |.. |......||.|||.||..|.. ..  ... .     ..|   ||.|.||..  .| ..   |.   .|| |. . ...  ...||  ||.
ndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkkevddllkkldidlivrahe

LVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDA
...|||...|| .||||.||| |. .  |.....  ...
vseeGyaflfdkrlvtvfsapyysgedtnlgavvvvsks

subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 41-277 1.7e-57 188.1 In-house 24-262 (284) alignment
Range on Protein: 41-277
Range on HMM: 24-262/284.0
NVQPVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQTKYGNANAW
 .  | .|. .|||||||| ||  ||   |    . |. .|| |||| .  ||   |.. |  ||..... |||||   | ..||||.||| .| .   .
mlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinkiygfyeecqrrynkpsvy

RYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAF-CDLVWSDPDNVE-TWAISPRGAGWLFGXKVTNXFVHXNNLKLICXAH
     ||  . ..|.. ...||.|||.|  .. . |.  |.|  . |   ..  |..|||| |..  |    ||  ..||      ..   .. |.  ||
vsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvfgsdalrklldrlqidlvvrah

QLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFND
|.||.||... . .|||..||| || .  | |...  | 
qvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnk

subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 44-278 4e-56 183.2 In-house 40-278 (290) alignment
Range on Protein: 44-278
Range on HMM: 40-278/290.0
PVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQTKYgNANAWRYC
 | .|... ||||||. .| . |   |. |.  .. .|| ||||  | |    |. .| ... .. | |||||  .. ..|||..|   |  ... |.  
eveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhevrkvnrlygfkeelarkr.gsrlwkqy

TKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERA--QEIPHKGAFCDLVWSDPDN--VETWAIS-PRGAGWLFGXKVTNXFVHXNNLKLICXAH
 .||. |.. | .....||.|||.|.....   .  ...   .   ..|   ||.|.||..   .| |.   |.   .|| |. . ...   |.||  ||
qdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialnkqraisvvfgkkglddllkklalslivrah

QLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDA
.. .||....||.|||||.||| |. .  |. .|.   ..
evkeegfnflfdkklvtvfsapyysgndtnlgaiatvses

subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 44-294 2.1e-53 174.5 In-house 44-295 (307) alignment
Range on Protein: 44-294
Range on HMM: 44-295/307.0
PVSTPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQTKYGN--ANAWR
 .  |. | ||.|||| || ..|   |. |.| |.  || ||||  | |.   |.| |  .|. ||| |||||  .. . ||||.|| |   .   . | 
didppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnkkygfyeecvtsipkcgeeiwa

YCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHKGAFCDLVWSDPDN-VETWAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQL
   ..|. | |.|.|  ..||.|||||| .  . ..    .    | .|   |..|.|||  |  |  | ||.|. || .| .  ..   ..||  |||.
lfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrgsgftfgtnviddvckrlgveliirahqm

VQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDatTREAKLFRNVPDSER
. .||  .   ||.|..||| ||    |   .|  ..  |   .|   ||.|| 
cfdgywvlsgrklitifsapmycnfyknagcvlkvde..tlgiqlvafvpesen

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 76-287 4.5e-49 160.4 In-house 121-332 (339) alignment
Range on Protein: 76-287
Range on HMM: 121-332/339.0
SYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQTKYgNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIX
 |. .|| |||| .| |    | .||  .|||| | ||||||  .   |||| | . .| .|. .    ..|... ..|.|.. ..|.|||.|  . .. 
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyry.daqlyecfqnmfnvfpfcavinntimcmhggisehltsfn

QIXMIERAQEIPHKGAFCDLVWSDPDNVET-WAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILA
|. ...|  |||  | . || |.|||  |  .  | ||| ..||      |..  .|...   ||.|..||...   .|||..|||||| .  | |....
qfsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfs

FNDATTREAKLFR
 .       ..||
idkklkisinvfr

subfamily_PPPLV_pd Subfamily PPPLV 26-274 2.9e-46 151.1 In-house 3-275 (290) alignment
Range on Protein: 26-274
Range on HMM: 3-275/290.0
KKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLE----ELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQIT
  |||   |  ..| .. .. .|. | ||.||.. ||      |.||| ..  .|.. .|| |||| .| |  . ||.||  .| ...| |||||   ..
lslcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvq

QVYGFYDECQTKYGNA--NAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQE-I--PHKGA--FCDLVWSDPDNVETWA-------
. . .. |.. |.|.   ..|   ..||| | .||.||..|.|||.|.   ..|  .|  |.   | .  . .||    |..||||.. .  .       
esieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvl

------ISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILA
       . || | .|. .  . |.. |||. .  ||.  ..|...  . .|.||.|. .||    . | || 
neGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssneaalilv

subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 21-275 1.3e-45 148.9 In-house 7-286 (302) alignment
Range on Protein: 21-275
Range on HMM: 7-286/302.0
PENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQ-----------IPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIV
 ...| .|.. | .|  .| ..  .|.|||. ||||||| ||  .. .  .                .. .|| ||||. | |  . ...||  .| . .
sksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyi

LXRGNHESXQITQVYGFYDECQTKYGNAN---AWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERA-QEIPHKGAFCDLVWSDPDNVET
| |||||.  |   ||| .| ....|...    |.   .||  . .||.. |..||||||.|| .... .|  |.|  .|. .     ||...|| .|..
llrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvql

WAISP----------RGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAF
 |. .          ||   .|     . . .  |||||  ||| . ||.|.. | ||.|..|||.|     |  ..|  
laavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkv

subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 21-275 1.6e-45 148.6 In-house 8-287 (302) alignment
Range on Protein: 21-275
Range on HMM: 8-287/302.0
PENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRTGGQ-----------IPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIV
 ...| .|.. | .|  .| ..  .|.|||. ||||||| ||  .. .  .                .. .|| ||||. | |  . ...||  .| . .
sksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyi

LXRGNHESXQITQVYGFYDECQTKYGNAN---AWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERA-QEIPHKGAFCDLVWSDPDNVET
| |||||.  |   ||| .| ....|...    |.   .||  . .||.. |..||||||.|| .... .|  |.|  .|. .     ||...|| .|..
llrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvql

WAISP----------RGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAF
 |. .          ||   .|     . . .  |||||  ||| . ||.|.. | ||.|..|||.|     |  ..|  
laavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkv

subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 46-277 1.3e-44 145.9 In-house 6-244 (263) alignment
Range on Protein: 46-277
Range on HMM: 6-244/263.0
STPVTVCGDIHGQFYDLEELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQTKYGNANA----WR
 .|. .||| |||. ||  .| . |    | |. .|| |||| .| |    |..||  .| .. | |||||   | . |||. | . ..   .     . 
qapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevyesvyn

YCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIXMIERAQEIPHK-GAFCDLVWSDPDNvETWAISP---RGAGWLFGXKVTNXFVHXNNLKLICXA
.  .||  . ..||. ...||.|||.|| .|.. .|  |    |  .     |||.|.||.. ..  . |   |    .|| |  . ...  .. ||  |
hfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpek.dakgfepnkiraisnvfgkkevddlckrldidlivra

HQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFND
||.|. || .. | .|.||.||  |     | |...  | 
hqvveygyaffadrrlitvfsasryqielcnyaavvvvnk

Metallophos Calcineurin-like phosphoesterase 48-240 8.4e-41 133.4 Pfam-A 2-198 (200) alignment
Range on Protein: 48-240
Range on HMM: 2-198/200.0
PVTVCGDIHGQFYDL----EELFRTGGQIPDTSYIXMGDXVDRGYYSXETFTRL--LTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQ----------
...|.||.||...||    ..|.. ... . . .. .|| |||| .| ||. .|  | || ..|....| |||||| .....|||..|.           
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange

-----------------------TKYGNANAWRYCTKVFDLLTIAAIIDEQVLCVHGGLSPDVKTIXQIxmieraqeiphkgafcdlvwsdpdnvetwai
                       ..... .|.... ..|..| ..|..| ..|..||.||.. ..  .|                               
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................

sprgAGWLFGXKVTNXFVHXNNLKLICXAHQL
    ...||| .... .   ....|.. .|. 
....gselfgpdalekllekygvdlvlrGHtH

subfamily_PPP7C_pd Subfamily PPP7C 45-183 2.3e-30 98.6 In-house 62-202 (383) alignment
Range on Protein: 45-183
Range on HMM: 62-202/383.0
VSTPVTVCGDIHGQFYDLEELF-RTGGQIPDTSYIXMGDXVDRGYYSXETFTRLLTLKAKFPDRIVLXRGNHESXQITQVYGFYDECQTKY--GNANAWR
.|  ||||||.||.. ||  .. . |   .. .|.  || ||||  | |    ||.|   .|  . | |||||   .   |||  | ..||   ...  |
iskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedhilnlryGfikeveskykvhgkkilr

YCTKVFDLLTIAAIIDEQVLCVHGGLSpDVKTIXQIXMIERA
   .||  | .|..|||..| ||||.| |   .  .  ||| 
lledvfawlplatlidekilivhGGis.dktdlelldkiers

subfamily_PPP7C_pd Subfamily PPP7C 193-279 2.6e-16 52.3 In-house 238-325 (383) alignment
Range on Protein: 193-279
Range on HMM: 238-325/383.0
CDLVWSDPDNVE-TWAISPRGAGWLFGXKVTNXFVHXNNLKLICXAHQLVQEGYKYMFDDKLVTVWSAPNYCYRCGNIASILAFNDAT
 |..|||| . |  .. . ||.|  ||  ||. ...  ||||.  .|.  .|||... |.|..|..|| ||     |  . . .....
ldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdl

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 18-68 7.4e-08 24.9 In-house 7-57 (317) alignment
Range on Protein: 18-68
Range on HMM: 7-57/317.0
KYLPENDLKKLCDLVXDLQLEECNVQPVSTPVTVCGDIHGQFYDLEELFRT
. . |..| .||    .|  .|     . .|||..||||||| ||  |.  
dlfkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldl