Gene PPPLV in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPPLV
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP165_AA protein Get Run
SpurP165_AA_26-119 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPPLV_pd Subfamily PPPLV 28-120 4.9e-48 156.9 In-house 193-285 (290) alignment
Range on Protein: 28-120
Range on HMM: 193-285/290.0
DENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVDRHKLRTIRL
|.. ..|   |.|||.|.||||||.||.||||.||..||||.|.|||||...|...||||.||||||||.|||.|||||.||||..|||.|. 
dlslrgelvlneGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssneaalilvdkkklriitt

0045823 Metallo-dependent phosphatases 37-119 2.2e-24 79.1 In-house 231-320 (473) alignment
Range on Protein: 37-119
Range on HMM: 231-320/473.0
SNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGK------LLTVFSSSHYCG-GSNEAACILVDRHKLRTIR
..  |  || ||.|..|. ||.|.||. |.| ...|.|.... |.... .||      ..||||...||| | | ||....| ...  | 
lrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedlisfiq

PPP_3 27-111 8.5e-23 73.7 In-house 174-259 (271) alignment
Range on Protein: 27-111
Range on HMM: 174-259/271.0
LDENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV-D
| ....|. ....... || ||.| .|. |. |.||. |.|. .|||||....|......||..|||| ..||.  ..|..||  .
lldlllssdpekeeglenskrGagllFgpdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkle

PP2Ac_SM00156 36-112 9.3e-22 70.3 In-house 182-258 (271) alignment
Range on Protein: 36-112
Range on HMM: 182-258/271.0
KSNNGFVFNSrRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCG-GSNEAACILVDR
....|| ... ||....|. ||...||. |||...||||||.. |... ...||.|.||...||.  || || . |. 
qkekgfqpsk.rglsvvFgedavkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkvek

subfamily_PPP5C_pd Subfamily PPP5C 33-112 6.7e-21 67.6 In-house 217-296 (322) alignment
Range on Protein: 33-112
Range on HMM: 217-296/322.0
SEIKSNNGFvFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDR
|. ...||   .|.||.|. |  |  ..||. |||...||.|||.. |..|...|||.||||.  ||  . | .| | .  
sdpqeanGr.spskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrg

PPP_1 29-107 1.1e-20 67.0 In-house 182-260 (264) alignment
Range on Protein: 29-107
Range on HMM: 182-260/264.0
ENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAAC
....|. |.....| || ||.|..|. |. |.||| |||. .||||||...|... .|.|..|.||.| |.   .... 
dillsddkeqeeavansiRGagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrga

0049330 Metallo-dependent phosphatases 36-113 9.8e-20 64.2 In-house 211-287 (309) alignment
Range on Protein: 36-113
Range on HMM: 211-287/309.0
KSNNGFVFNSrRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVDRH
   .||. |  || |. | ..|.||||..|.|...||.|.... |...  .|||.||||...|||  . ....|.   
piregfapnp.rglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleide

subfamily_PPP1C_pd Subfamily PPP1C 38-114 1.9e-17 56.3 In-house 193-269 (282) alignment
Range on Protein: 38-114
Range on HMM: 193-269/282.0
NNGFVFNSrRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDRHK
..|.  |. ||  . |. |..|.||| |.|. ..|||.| ..|..  .| .|.||||...|||   |..| . ||...
vlgwsend.rGvsftfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeel

0053225 Metallo-dependent phosphatases 33-110 2.7e-17 56.4 In-house 200-276 (293) alignment
Range on Protein: 33-110
Range on HMM: 200-276/293.0
SEIKSNNGFVFNsRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV
|.    .|.. .  || |. | ..|..|||. |.| ..||.|.|.. |...  .|||.||||...|.|. . ....|.
sdpdlwsgwlps.yrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavla

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 43-112 9.7e-17 54.1 In-house 233-303 (317) alignment
Range on Protein: 43-112
Range on HMM: 233-303/317.0
FNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV-DR
 .| ||.|..|  .|...||.  .|  |.|||.| . |..  .  ||.|.||.  |||  ...|..|  |.
kesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavlsvdk

subfamily_PPP3C_pd Subfamily PPP3C 31-114 1.6e-16 53.2 In-house 223-313 (452) alignment
Range on Protein: 31-114
Range on HMM: 223-313/452.0
QMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQK------GKLLTVFSSSHYCGGSNEAACILV-DRHK
. .| |... || || ||  ...|  |  .||| |.|  .|||||.|.||.....|        |.|.||.. |..  |. | .|  .  .
dygeekteekfvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennv

subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 43-113 4.8e-16 52.0 In-house 201-272 (284) alignment
Range on Protein: 43-113
Range on HMM: 201-272/284.0
FNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACIL-VDRH
 .|.||.|..|  .|...||.  .|  |.|||.| . |..     ||.|.||.  |||  ...|..| ||..
kesprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdee

subfamily_PPG1_pd Subfamily PPG1 34-114 5.4e-16 51.7 In-house 204-285 (300) alignment
Range on Protein: 34-114
Range on HMM: 204-285/300.0
EIKSNNG-FVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVDRHK
.   ..| .  .|.||.|. .  |  |.||. |.. ..||||.. . |.|.   .|| ||.|.  ||    . | ||   .|
dhpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyek

subfamily_PPP7C_pd Subfamily PPP7C 32-110 6.7e-16 51.0 In-house 242-321 (383) alignment
Range on Protein: 32-110
Range on HMM: 242-321/383.0
MSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSH-YCGGSNEAACILV
 |. |...| . |. ||.|  |  |  ...||  ||. .||.|| .. |...  . |.||.||.|  |  |||  | . .
wsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvkl

subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 36-111 2.5e-15 49.1 In-house 193-269 (287) alignment
Range on Protein: 36-111
Range on HMM: 193-269/287.0
KSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACI-LVD
| ...| .|  |.   .|    .. .|.  ... ..|||||.. |..   . .|.||||...|.|   . ...  |.
kdaktfelnkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvs

subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 37-109 3.5e-15 48.8 In-house 201-273 (290) alignment
Range on Protein: 37-109
Range on HMM: 201-273/290.0
SNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACIL
 .. . .| .|.   .|  ..|. .|.   || ..|||||.. ||. . . ||.||||. .|.|   .  .|.
kddtialnkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaia

subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 37-112 7.6e-14 44.4 In-house 207-282 (298) alignment
Range on Protein: 37-112
Range on HMM: 207-282/298.0
SNNGFVFNsRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNE-AACILVDR
. .|.  |  || . .|  |... .|.  ..  |.||| | | |..   . ||.|.||. ||||  .. || . || 
avkgwaen.srGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvde

subfamily_PPP4C_pd Subfamily PPP4C 44-113 8.4e-14 44.4 In-house 204-274 (288) alignment
Range on Protein: 44-113
Range on HMM: 204-274/288.0
NSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACIL-VDRH
 | ||.|..|  |. |.| . |... ..|||.. . |.... . |.|||.|.  ||    . | || .| .
vsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldee

subfamily_PPP2C_pd Subfamily PPP2C 37-112 1.4e-13 43.7 In-house 199-274 (290) alignment
Range on Protein: 37-112
Range on HMM: 199-274/290.0
SNNGFVfNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDR
  .|..  |.||.|. |  |  |.| . |.|....|||..   |...  . .. |.||.  ||    |.|| . .| 
drggwg.isprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaaileldd

subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 42-111 3.3e-13 42.5 In-house 194-263 (281) alignment
Range on Protein: 42-111
Range on HMM: 194-263/281.0
VFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVD
 ..| ||....|  . ..   .  ..  .|||| | |.|..| .  ||.||||   ||   ..||..|  
wkassrGssftfGknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkv

subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 39-110 4e-13 42.4 In-house 189-259 (284) alignment
Range on Protein: 39-110
Range on HMM: 189-259/284.0
NGFVFNSrRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV
.|.  || ||  ..|  ||| ..|.  ..  |.|||.| | |...  . .|.|.||.  |||  ..||... 
kgwnpns.rgvsyvfgsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmy

subfamily_PPP6C_pd Subfamily PPP6C 44-110 4.3e-13 42.1 In-house 203-269 (290) alignment
Range on Protein: 44-110
Range on HMM: 203-269/290.0
NSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV
 | ||.|..|     . |...|||. ..|||.. . |.. . . || ||.|.  ||    . |.|| 
vsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasila

subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 25-113 5.2e-13 41.8 In-house 200-289 (302) alignment
Range on Protein: 25-113
Range on HMM: 200-289/302.0
EFLDENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDRH
. || ...  ....  ...|  ||  ..|   |.. . .  ||. ..||| .  .||.   . ||||.||.. |   | |. | . ||  
dpldvqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtn

subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 25-113 5.5e-13 41.8 In-house 201-290 (302) alignment
Range on Protein: 25-113
Range on HMM: 201-290/302.0
EFLDENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDRH
. || ...  ....  ...|  ||  ..|   |.. . .  ||. ..||| .  .||.   . ||||.||.. |   | |. | . ||  
dpldvqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtn

subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 35-115 9.4e-13 41.1 In-house 206-285 (297) alignment
Range on Protein: 35-115
Range on HMM: 206-285/297.0
IKSNNGFVfNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVDRHKL
|    ||. . .||.|  |  ||. .     .|  | |||.| | |...    ||.|.||. ||||  ...|...    ||
isglsgfm.enqrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdekl

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 44-115 4.4e-12 38.7 In-house 253-324 (339) alignment
Range on Protein: 44-115
Range on HMM: 253-324/339.0
NSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVDRHKL
 | ||.  .|   ||  ||.  .|  ||| |.| . |... .  .|.|.||.  |||  ...|...   .||
psargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfsidkkl

subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 45-113 7.8e-12 38.1 In-house 214-283 (299) alignment
Range on Protein: 45-113
Range on HMM: 214-283/299.0
SRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDRH
  ||  ..|  | ..  ..  ..  | |||.| | |..   . ||.|.||. ||||   | || . ||  
nvrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvden

subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 39-112 2.5e-11 36.2 In-house 190-263 (280) alignment
Range on Protein: 39-112
Range on HMM: 190-263/280.0
NGFVfNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSN-EAACILVDR
 |.  .. ||. ..|  . .  . .  ..  ..| |.| | |..   . ||.||||. .|.|  . .|| . || 
tgwa.ensrgvsvifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivde

subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 36-110 5.7e-11 35.4 In-house 186-260 (280) alignment
Range on Protein: 36-110
Range on HMM: 186-260/280.0
KSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV
  .    | | ||  .||    .|.  .  ..  .||||.| | |...    .|.||||   ||    .||....
tnkgegwfhsirgisymfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvc

PPP_2 28-77 2e-10 33.7 In-house 149-198 (198) alignment
Range on Protein: 28-77
Range on HMM: 149-198/198.0
DENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQ
 |...|. |...... || ||.| .|. |. |..|. |.|. .||||||.
eeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHevk

PPP_4 28-77 3.7e-09 29.9 In-house 147-197 (197) alignment
Range on Protein: 28-77
Range on HMM: 147-197/197.0
DENQ-MSEI-KSNNGfVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQ
 ...  |.  ....| . || || |..|. |. |.||. |||. .||.||..
kdlllwsdpreaqeg.lansvrGagllFgpdvtekfleknnlkliirshelk

subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 44-110 7.2e-09 28.2 In-house 211-277 (307) alignment
Range on Protein: 44-110
Range on HMM: 211-277/307.0
NSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV
 | ||.|  |  . ..   .   .  .||||..   |. |    ||.|.||.  ||   ..| |.| 
assrgsgftfgtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlk

subfamily_PPZ_pd Subfamily PPZ 37-107 2e-08 27.1 In-house 207-276 (300) alignment
Range on Protein: 37-107
Range on HMM: 207-276/300.0
SNNGFVFNsRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAAC
|.| .  |  ||  . .   |...||.   .  | ||| | . |... .   |.||||.  |||  ..  .
ssnewedn.ergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwga

PPP_5_Dcr2 33-76 3.5e-08 26.6 In-house 154-198 (199) alignment
Range on Protein: 33-76
Range on HMM: 154-198/199.0
SEI-KSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEV
|.  .. .|   || || |..|. |. |.||. |||. .||.||.
sdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshel

subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 36-112 1.4e-06 21.2 In-house 167-244 (263) alignment
Range on Protein: 36-112
Range on HMM: 167-244/263.0
KSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCG-GSNEAACILVDR
|  .||  |  |    .|    .. . .  ..  ..|||.| . |. .    .|.||||.|.|     | || ..|..
kdakgfepnkiraisnvfgkkevddlckrldidlivrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnk