Gene PPPLV in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPPLV
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP165_AA protein Get Run
SpurP165_AA_26-119 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPPLV_pd Subfamily PPPLV 28-120 4.9e-48 156.9 In-house 193-285 (290) alignment 
Range on Protein: 28-120
Range on HMM: 193-285/290.0
DENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVDRHKLRTIRL
|.. ..|   |.|||.|.||||||.||.||||.||..||||.|.|||||...|...||||.||||||||.|||.|||||.||||..|||.|. 
dlslrgelvlneGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssneaalilvdkkklriitt
0045823 Metallo-dependent phosphatases 37-119 2.2e-24 79.1 In-house 231-320 (473) alignment 
Range on Protein: 37-119
Range on HMM: 231-320/473.0
SNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGK------LLTVFSSSHYCG-GSNEAACILVDRHKLRTIR
..  |  || ||.|..|. ||.|.||. |.| ...|.|.... |.... .||      ..||||...||| | | ||....| ...  | 
lrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedlisfiq
PPP_3 27-111 8.5e-23 73.7 In-house 174-259 (271) alignment 
Range on Protein: 27-111
Range on HMM: 174-259/271.0
LDENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV-D
| ....|. ....... || ||.| .|. |. |.||. |.|. .|||||....|......||..|||| ..||.  ..|..||  .
lldlllssdpekeeglenskrGagllFgpdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkle
PP2Ac_SM00156 36-112 9.3e-22 70.3 In-house 182-258 (271) alignment 
Range on Protein: 36-112
Range on HMM: 182-258/271.0
KSNNGFVFNSrRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCG-GSNEAACILVDR
....|| ... ||....|. ||...||. |||...||||||.. |... ...||.|.||...||.  || || . |. 
qkekgfqpsk.rglsvvFgedavkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkvek
subfamily_PPP5C_pd Subfamily PPP5C 33-112 6.7e-21 67.6 In-house 217-296 (322) alignment 
Range on Protein: 33-112
Range on HMM: 217-296/322.0
SEIKSNNGFvFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDR
|. ...||   .|.||.|. |  |  ..||. |||...||.|||.. |..|...|||.||||.  ||  . | .| | .  
sdpqeanGr.spskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrg
PPP_1 29-107 1.1e-20 67.0 In-house 182-260 (264) alignment 
Range on Protein: 29-107
Range on HMM: 182-260/264.0
ENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAAC
....|. |.....| || ||.|..|. |. |.||| |||. .||||||...|... .|.|..|.||.| |.   .... 
dillsddkeqeeavansiRGagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrga
0049330 Metallo-dependent phosphatases 36-113 9.8e-20 64.2 In-house 211-287 (309) alignment 
Range on Protein: 36-113
Range on HMM: 211-287/309.0
KSNNGFVFNSrRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVDRH
   .||. |  || |. | ..|.||||..|.|...||.|.... |...  .|||.||||...|||  . ....|.   
piregfapnp.rglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleide
subfamily_PPP1C_pd Subfamily PPP1C 38-114 1.9e-17 56.3 In-house 193-269 (282) alignment 
Range on Protein: 38-114
Range on HMM: 193-269/282.0
NNGFVFNSrRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDRHK
..|.  |. ||  . |. |..|.||| |.|. ..|||.| ..|..  .| .|.||||...|||   |..| . ||...
vlgwsend.rGvsftfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeel
0053225 Metallo-dependent phosphatases 33-110 2.7e-17 56.4 In-house 200-276 (293) alignment 
Range on Protein: 33-110
Range on HMM: 200-276/293.0
SEIKSNNGFVFNsRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV
|.    .|.. .  || |. | ..|..|||. |.| ..||.|.|.. |...  .|||.||||...|.|. . ....|.
sdpdlwsgwlps.yrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavla
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 43-112 9.7e-17 54.1 In-house 233-303 (317) alignment 
Range on Protein: 43-112
Range on HMM: 233-303/317.0
FNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV-DR
 .| ||.|..|  .|...||.  .|  |.|||.| . |..  .  ||.|.||.  |||  ...|..|  |.
kesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavlsvdk
subfamily_PPP3C_pd Subfamily PPP3C 31-114 1.6e-16 53.2 In-house 223-313 (452) alignment 
Range on Protein: 31-114
Range on HMM: 223-313/452.0
QMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQK------GKLLTVFSSSHYCGGSNEAACILV-DRHK
. .| |... || || ||  ...|  |  .||| |.|  .|||||.|.||.....|        |.|.||.. |..  |. | .|  .  .
dygeekteekfvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennv
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 43-113 4.8e-16 52.0 In-house 201-272 (284) alignment 
Range on Protein: 43-113
Range on HMM: 201-272/284.0
FNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACIL-VDRH
 .|.||.|..|  .|...||.  .|  |.|||.| . |..     ||.|.||.  |||  ...|..| ||..
kesprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdee
subfamily_PPG1_pd Subfamily PPG1 34-114 5.4e-16 51.7 In-house 204-285 (300) alignment 
Range on Protein: 34-114
Range on HMM: 204-285/300.0
EIKSNNG-FVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVDRHK
.   ..| .  .|.||.|. .  |  |.||. |.. ..||||.. . |.|.   .|| ||.|.  ||    . | ||   .|
dhpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyek
subfamily_PPP7C_pd Subfamily PPP7C 32-110 6.7e-16 51.0 In-house 242-321 (383) alignment 
Range on Protein: 32-110
Range on HMM: 242-321/383.0
MSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSH-YCGGSNEAACILV
 |. |...| . |. ||.|  |  |  ...||  ||. .||.|| .. |...  . |.||.||.|  |  |||  | . .
wsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvkl
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 36-111 2.5e-15 49.1 In-house 193-269 (287) alignment 
Range on Protein: 36-111
Range on HMM: 193-269/287.0
KSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACI-LVD
| ...| .|  |.   .|    .. .|.  ... ..|||||.. |..   . .|.||||...|.|   . ...  |.
kdaktfelnkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvs
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 37-109 3.5e-15 48.8 In-house 201-273 (290) alignment 
Range on Protein: 37-109
Range on HMM: 201-273/290.0
SNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACIL
 .. . .| .|.   .|  ..|. .|.   || ..|||||.. ||. . . ||.||||. .|.|   .  .|.
kddtialnkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaia
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 37-112 7.6e-14 44.4 In-house 207-282 (298) alignment 
Range on Protein: 37-112
Range on HMM: 207-282/298.0
SNNGFVFNsRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNE-AACILVDR
. .|.  |  || . .|  |... .|.  ..  |.||| | | |..   . ||.|.||. ||||  .. || . || 
avkgwaen.srGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvde
subfamily_PPP4C_pd Subfamily PPP4C 44-113 8.4e-14 44.4 In-house 204-274 (288) alignment 
Range on Protein: 44-113
Range on HMM: 204-274/288.0
NSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACIL-VDRH
 | ||.|..|  |. |.| . |... ..|||.. . |.... . |.|||.|.  ||    . | || .| .
vsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldee
subfamily_PPP2C_pd Subfamily PPP2C 37-112 1.4e-13 43.7 In-house 199-274 (290) alignment 
Range on Protein: 37-112
Range on HMM: 199-274/290.0
SNNGFVfNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDR
  .|..  |.||.|. |  |  |.| . |.|....|||..   |...  . .. |.||.  ||    |.|| . .| 
drggwg.isprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaaileldd
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 42-111 3.3e-13 42.5 In-house 194-263 (281) alignment 
Range on Protein: 42-111
Range on HMM: 194-263/281.0
VFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVD
 ..| ||....|  . ..   .  ..  .|||| | |.|..| .  ||.||||   ||   ..||..|  
wkassrGssftfGknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkv
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 39-110 4e-13 42.4 In-house 189-259 (284) alignment 
Range on Protein: 39-110
Range on HMM: 189-259/284.0
NGFVFNSrRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV
.|.  || ||  ..|  ||| ..|.  ..  |.|||.| | |...  . .|.|.||.  |||  ..||... 
kgwnpns.rgvsyvfgsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmy
subfamily_PPP6C_pd Subfamily PPP6C 44-110 4.3e-13 42.1 In-house 203-269 (290) alignment 
Range on Protein: 44-110
Range on HMM: 203-269/290.0
NSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV
 | ||.|..|     . |...|||. ..|||.. . |.. . . || ||.|.  ||    . |.|| 
vsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasila
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 25-113 5.2e-13 41.8 In-house 200-289 (302) alignment 
Range on Protein: 25-113
Range on HMM: 200-289/302.0
EFLDENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDRH
. || ...  ....  ...|  ||  ..|   |.. . .  ||. ..||| .  .||.   . ||||.||.. |   | |. | . ||  
dpldvqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtn
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 25-113 5.5e-13 41.8 In-house 201-290 (302) alignment 
Range on Protein: 25-113
Range on HMM: 201-290/302.0
EFLDENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDRH
. || ...  ....  ...|  ||  ..|   |.. . .  ||. ..||| .  .||.   . ||||.||.. |   | |. | . ||  
dpldvqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtn
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 35-115 9.4e-13 41.1 In-house 206-285 (297) alignment 
Range on Protein: 35-115
Range on HMM: 206-285/297.0
IKSNNGFVfNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVDRHKL
|    ||. . .||.|  |  ||. .     .|  | |||.| | |...    ||.|.||. ||||  ...|...    ||
isglsgfm.enqrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdekl
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 44-115 4.4e-12 38.7 In-house 253-324 (339) alignment 
Range on Protein: 44-115
Range on HMM: 253-324/339.0
NSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVDRHKL
 | ||.  .|   ||  ||.  .|  ||| |.| . |... .  .|.|.||.  |||  ...|...   .||
psargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfsidkkl
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 45-113 7.8e-12 38.1 In-house 214-283 (299) alignment 
Range on Protein: 45-113
Range on HMM: 214-283/299.0
SRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDRH
  ||  ..|  | ..  ..  ..  | |||.| | |..   . ||.|.||. ||||   | || . ||  
nvrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvden
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 39-112 2.5e-11 36.2 In-house 190-263 (280) alignment 
Range on Protein: 39-112
Range on HMM: 190-263/280.0
NGFVfNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSN-EAACILVDR
 |.  .. ||. ..|  . .  . .  ..  ..| |.| | |..   . ||.||||. .|.|  . .|| . || 
tgwa.ensrgvsvifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivde
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 36-110 5.7e-11 35.4 In-house 186-260 (280) alignment 
Range on Protein: 36-110
Range on HMM: 186-260/280.0
KSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV
  .    | | ||  .||    .|.  .  ..  .||||.| | |...    .|.||||   ||    .||....
tnkgegwfhsirgisymfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvc
PPP_2 28-77 2e-10 33.7 In-house 149-198 (198) alignment 
Range on Protein: 28-77
Range on HMM: 149-198/198.0
DENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQ
 |...|. |...... || ||.| .|. |. |..|. |.|. .||||||.
eeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHevk
PPP_4 28-77 3.7e-09 29.9 In-house 147-197 (197) alignment 
Range on Protein: 28-77
Range on HMM: 147-197/197.0
DENQ-MSEI-KSNNGfVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQ
 ...  |.  ....| . || || |..|. |. |.||. |||. .||.||..
kdlllwsdpreaqeg.lansvrGagllFgpdvtekfleknnlkliirshelk
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 44-110 7.2e-09 28.2 In-house 211-277 (307) alignment 
Range on Protein: 44-110
Range on HMM: 211-277/307.0
NSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV
 | ||.|  |  . ..   .   .  .||||..   |. |    ||.|.||.  ||   ..| |.| 
assrgsgftfgtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlk
subfamily_PPZ_pd Subfamily PPZ 37-107 2e-08 27.1 In-house 207-276 (300) alignment 
Range on Protein: 37-107
Range on HMM: 207-276/300.0
SNNGFVFNsRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAAC
|.| .  |  ||  . .   |...||.   .  | ||| | . |... .   |.||||.  |||  ..  .
ssnewedn.ergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwga
PPP_5_Dcr2 33-76 3.5e-08 26.6 In-house 154-198 (199) alignment 
Range on Protein: 33-76
Range on HMM: 154-198/199.0
SEI-KSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEV
|.  .. .|   || || |..|. |. |.||. |||. .||.||.
sdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshel
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 36-112 1.4e-06 21.2 In-house 167-244 (263) alignment 
Range on Protein: 36-112
Range on HMM: 167-244/263.0
KSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCG-GSNEAACILVDR
|  .||  |  |    .|    .. . .  ..  ..|||.| . |. .    .|.||||.|.|     | || ..|..
kdakgfepnkiraisnvfgkkevddlckrldidlivrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnk