Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PFKFB_pd | Subfamily PFKFB | 273-468 | 7e-99 | 321.2 | In-house | 1-197 (198) | alignment | ||
Range on Protein: 273-468
Range on HMM: 1-197/198.0
NIHIIPRTIYLTRHGESMHNQNGRIGGDANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSIDVAIEQWKSLDELDAGVCDGLTYEEIQKG
|||. ||.|||.|||||..|..||||||..|.|||..|...|.......||..|.||||.||||.|||. ... |||| |||||||.|||||||||..
nihlkpreiylvRhGeseknkkgriggdseLterGveyakklakfikeenlkelrvwtselkrtiqTaellglpkeqwkaLdeldaGkcdgltyeeikek
HPEEFALRDQDKFHYRYPMGESYQDLVARLEPVIMELER-QKNVLVICHQGVMRCLLAYFLDKNSDELPYLKCPLHTVIKLTPVAYGCRVETVTLNI
.||||. |..||..||||.||||.|||.||||||.|||| |.|||.|.|| |.|.||||.|||. .||||||.|||||||||||||||.||...|..
fpeefkerkkdkyryryprgEsyedlvqRlepvileLereqenvliiaHqavlrvllaylldksaeelpylkvplhtvikltpvaYgckvellkldv
|
|||||||||
6PF2K | 6-phosphofructo-2-kinase | 50-277 | 1.6e-89 | 289.1 | Pfam-A | 6-222 (223) | alignment | ||
Range on Protein: 50-277
Range on HMM: 6-222/223.0
MPSLHKPHAVIVMVGLPARGKTYIAKKLARYLNWIGINTKVFNVGEYRRKAVSGEISHDFFRHDNAEAYKIRLQCAKEALEDMANWLD-EDGEVAVFDAT
...|.. . |||.|||||||||||.||| |||.|.|..|||||||.|||.||. . . .|||.||.|| |.| ..|..||.|....| |.|.||.||||
vknlknsklvivlvGLpargKtyiskkltrylkwlgvrtkvFnvgkyrreavkalsdaeffrpdneealklreklalaalkdllkylneeegqvaifDAt
NTTRDRRQTILEFLGERHiklikfllnvfiFLVFLCESVCDDPVTVQSIIREVKLNSPDYYDIDKERAIRDFLQRIEHYKETYQSLSDDHDRNLSYIKII
||||.||..||||. |.. . |.. ||||.|. ... |.||||.|||| | ..| ||.|||.|.|.|...|..|.|..|..|||||.|
NttrerRklilefveenn............lkvlflesvcsdeeiikeNikevklsspDYkdketeeaikdflkRlenyekqyeplddeedeelsyIkvi
NVGDRFLVNKVSGHIQSRVVYYLMNIHII
.|| ...||.|.|..|||.||||.|||
dvgkslvvnnvqgylqsrivyyllNihlk
|
|||||||||
0035570 | Phosphoglycerate mutase-like | 280-484 | 1.4e-59 | 193.4 | In-house | 1-205 (219) | alignment | ||
Range on Protein: 280-484
Range on HMM: 1-205/219.0
TIYLTRHGESMHNQNGRIGGDANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSIDVAIEQWKSLDELDAGVCDGLTYEEIQKGHPEEFAL
..||.||||...| .||. ||..|.|||. ..| |||... .... .|..| |.|..||| |.. .|... | |.|.|...|||..||.. .|||.|.
rlyLvRHGetewnlegrlqgdvpLterGreqaralgealadlgipfdavysSpllRaiqTaeiiglpveidprLrEidfgdlegltldeiaekypeelaa
RDQDKFHYRYPMGESYQDLVARLEPVIMELERQKNVLVICHQGVMRCLLAYFLDKNSDELPYLKCPLHTVIKLTPVAYGCRVETVTLNIPAVDTHRPRPD
. .|...||.| |||..|.|||..|...|||...||||..|.||.|.||||.|. . .|...|..| ..|..|.. ..|.... |.||. .. ... ..
wlrdpydyrppggEsladvvaRvlpaleeledgenvlvVsHggvirallayllglpleeilrlnlpngsvtvleldggggkwvlvllndtshlelllell
ECNTN
....
llsll
|
|||||||||
0039931 | Phosphoglycerate mutase-like | 280-483 | 1.7e-59 | 193.0 | In-house | 1-204 (219) | alignment | ||
Range on Protein: 280-483
Range on HMM: 1-204/219.0
TIYLTRHGESMHNQNGRIGGDANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSIDVAIEQWKSLDELDAGVCDGLTYEEIQKGHPEEFAL
..||.||||...| .||. ||..|.|||. ..| |||... ..|. |..| |.|..||| |.. .|... | |.|.|...|||.|||.. .|||.|.
rlyLvRHGetewnvegrlqgdspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeiiglpveidprLrEidfgdlegltleeiaekypeelaa
RDQDKFHYRYPMGESYQDLVARLEPVIMELERQKNVLVICHQGVMRCLLAYFLDKNSDELPYLKCPLHTVIKLTPVAYGCRVETVTLNIPAVDTHRPRPD
. .|...||.| |||..|.|||..|...||....||||..|.||.|.||||.|. . .|...|..| ..|..|.. ..|...... |. . |..|...
wlrdpydyrppggEsladvvaRvlpaleellagenvlvVsHggvirallayllglsleeilrlnlpngsvtvlelddggwvlvllnltshlddllrllll
ECNT
...
tlel
|
|||||||||
0053607 | Phosphoglycerate mutase-like | 278-462 | 1.9e-53 | 173.0 | In-house | 1-185 (191) | alignment | ||
Range on Protein: 278-462
Range on HMM: 1-185/191.0
PRTIYLTRHGESMHNQNGRIGGDANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSIDVAIEQWKSLDELDAGVCDGLTYEEIQKGHPEEF
....|| ||||...| .||. ||..|.|.|. . | |.|.. ..|. .|..| |.|..||| |.. .|... | |.|.|...|||.||... .|||.
mtrlyLvRHGetewnaegrlqgdvpLtelGreqaralaellaelglkfdavysSpllRarqTaeiiglpvevdprlrEidfgdwegltleelaekypeel
ALRDQDKFHYRYPMGESYQDLVARLEPVIMELERQKNVLVICHQGVMRCLLAYFLDKNSDELPYLKCPLHTVIKLTPVAYGCRVE
|.. .|...||.| |||..|..||..|...|| ...||||..|.||.|.||||.|. . .||..|..| ..|..|.. .|....
aawlrdpldyrppggEsladvaaRvlpaleellaggnvlvVaHggvirallayllglpleellrlnlpngsvtvlelddggwvlv
|
|||||||||
0036777 | Phosphoglycerate mutase-like | 278-469 | 4.1e-53 | 172.7 | In-house | 2-232 (247) | alignment | ||
Range on Protein: 278-469
Range on HMM: 2-232/247.0
PRTIYLTRHGESMHNQNGRIGG--DANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSI----D---VAIEQWKSLDELDAGVCDGLTYEE
....||.||||...|..||. | |..|.|.|. . . |||......|. .|..| |.|..||| | . . ..... | |.| |...|||..|
mkrlyLvRHGetewnaegrfqgwlDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiilealglsllpvvvdprLrErdyGalegltkae
IQKGHPEEFALRDQDKFHYRY-------------------------PMGESYQDLVARLEPVIMELERQ-----KNVLVICHQGVMRCLLAYFLDKNSDE
|.. .|||.... .|...||. | |||..|.|||..|...|| .. .||||..|.||.|.||||.|. . ..
iaekypeelvawwrdpydyrppllelllelllldllryallpldllpggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllglsled
LPYLKCPLHTVIKLTPVAYGCRVETVTLNIP
...|..| .....|. ..| .. ..|| .
ilrlnlpngsitvleldddgklwvleslndt
|
|||||||||
0037864 | Phosphoglycerate mutase-like | 272-463 | 1.5e-51 | 167.0 | In-house | 1-206 (211) | alignment | ||
Range on Protein: 272-463
Range on HMM: 1-206/211.0
MNIHIIPRTIYLTRHGESMHNQNGRIGG--DANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSI----D---VAIEQWKSLDELDAGVCD
|.........||.||||...|..||. | |..|.|.|. . | |||.. ..|. |..| |.|..||| | . . .|... | |.| |...
MslnllmtrlyLvRHGetewnaegrlqgwldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiilealglpllpvevdprlrErdfgale
GLTYEEIQKGHPEEFALRDQDKFHYRYPMGESYQDLVARLEPVIMELERQ-----KNVLVICHQGVMRCLLAYFLDKNSDELPYLKCPLHTVIKLTPVAY
|||.|||.. .|||.. . .|....|.| |||..|.|||..|...|| .. .||||..|.||.|.||||.|. . .||..|..| ..|..|. .
gltleeiaekypeelvawlrdpydfrppggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllglsleellrlnlpngsvtvlelddg
GCRVET
|.....
gwvlvs
|
|||||||||
0051064 | Phosphoglycerate mutase-like | 278-469 | 1.8e-51 | 167.7 | In-house | 3-233 (241) | alignment | ||
Range on Protein: 278-469
Range on HMM: 3-233/241.0
PRTIYLTRHGESMHNQNGRIGG--DANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTAS----SID---VAIEQWKSLDELDAGVCDGLTYEE
....|| |||||..| .||. | |..|.|.|. ..| |||... .... .|..| |.|..||| .. . ..... | |.| |...|||.||
mkrlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaealglpllpvvvdprlrEidfgalegltlee
IQKGHPEEFALRDQDKFHYRY-------------------------PMGESYQDLVARLEPVIMELERQ-----KNVLVICHQGVMRCLLAYFLDKNSDE
|.. .|||......|....|. | |||..|..||..|.. || .. |||||..|.||.|.||||.|. . .|
iaekfpeelvawlrdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleellarllldgknvlvVsHggvirallayllglplee
LPYLKCPLHTVIKLTPVAYGCRVETVTLNIP
|..|..| ..|..|. ..|.|| |.|| .
llrlnlpngsvtvleldddgkrvvlvllndt
|
|||||||||
0043909 | Phosphoglycerate mutase-like | 278-461 | 9.2e-51 | 164.9 | In-house | 2-228 (249) | alignment | ||
Range on Protein: 278-461
Range on HMM: 2-228/249.0
PRTIYLTRHGESMHNQNGRIGG--DANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSI----D---VAIEQWKSLDELDAGVCDGLTYEE
....|| ||||...|..||. | |..|.|.|. | |||........ .|..| |||..||| | . . .|... | |.| |...|||..|
mkrlyLvRHGetewnaegrfqgwlDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileelgldklpvevdprLrErdfGalegltkae
IQKGHPEEFALRDQ-----------------------------DKFHYRYPMGESYQDLVARLEPVIMELERQ-----KNVLVICHQGVMRCLLAYFLDK
| . .|||.... . |....|.| |||..|.|||..|...|| .. .|||...|.||.|.||||.|.
iaekypeelvawlrrsydvlpplleeldelllellldyaladldplldrppggEsladvvaRvlpaleellarllkdggnvliVaHggvlrallayllgl
NSDELPYLKCPLHTVIKLTPVAYGCRV
. .....|..| .....|.. ..|. |
sledilrlnlpngsitvlelddggkpv
|
|||||||||
0049178 | Phosphoglycerate mutase-like | 278-463 | 1.4e-50 | 164.5 | In-house | 3-225 (243) | alignment | ||
Range on Protein: 278-463
Range on HMM: 3-225/243.0
PRTIYLTRHGESMHNQNGRIGG--DANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSI----D---VAIEQWKSLDELDAGVCDGLTYEE
....|| ||||...|. ||. | |..|.|.|. | |||......|. |..| |||..||| | . . ..... | |.| |...|||..|
mtrlyLvRHGetewnaegrlqgwtDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiilealglpllpvvvdprLrErdfGalegltkae
IQKGHPEEFALRDQDKFHYRY-----------------------PMGESYQDLVARLEPVIMELERQ-----KNVLVICHQGVMRCLLAYFLDKNSDELP
|.. .|||.... .|....|. | |||..|..||..|...|| .. |.|||..|.||.|.|||..|. . .||.
iaakypeelvawwrdpydarppalllldlllplldrlladldllpggEsladvaaRvlpaleellaellhdgktvlvVaHggvirallalllglpleell
YLKCPLHTVIKLTPVAYGCRVET
.|..| ..|..|. .|.....
rlnlpngsvtvlelddggwvlvs
|
|||||||||
0036887 | Phosphoglycerate mutase-like | 278-463 | 2.6e-49 | 159.8 | In-house | 1-194 (202) | alignment | ||
Range on Protein: 278-463
Range on HMM: 1-194/202.0
PRTIYLTRHGESMHNQNGRIGG--DANLSERGWSYSRSLGEYMStqNLQDLKVWTSRLKRTVQTASSI----DVAIEQWKSLDELDAGVCDGLTYEEIQK
....||.||||...|..||. | |..|.|.|. . | |||... .|. |..| |.|..||| | .. ..... | |.| |...|||.|||..
mtrlyLvRHGetewnvegrlqgdldvpLtelGreqaralgerla..glpfdavysSpllRaiqTaeiiaealglpvivdprlrEidfgalegltleeiae
GHPEEFALRDQDKFHYRYPMGESYQDLVARLEPVIMELERQ---KNVLVICHQGVMRCLLAYFLDKNSDELPYLK-CPLHTVIKLTPVAYGCRVET
.|||.| . .|....|.| |||..|.|||......|| .. .||||..|.||.|.||||.|. . ..|..|. .| ..|..|. ..|.....
kypeelaawlrdpydfrppggEsladvvaRvlaaleellarldggnvlvVsHggvlrallayllglsledllrlrklpngsvtvlelddggwvlvl
|
|||||||||
0048955 | Phosphoglycerate mutase-like | 280-460 | 3.3e-49 | 160.2 | In-house | 2-221 (240) | alignment | ||
Range on Protein: 280-460
Range on HMM: 2-221/240.0
TIYLTRHGESMHNQNGRIGG--DANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTAS----SID---VAIEQWKSLDELDAGVCDGLTYEEIQ
..|| |||||..| .||. | |..|.|.|. ..| |||... .... .|..| |.|..||| .. . .... | |.| |...|||..||.
rlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaealglpllpvvvdprlrErdfgalegltldeia
KGHPEEFALRDQDKFHYRY-------------------------PMGESYQDLVARLEPVIMELE-----RQKNVLVICHQGVMRCLLAYFLDKNSDELP
. .|||..|. .|....|. | |||..|..||..... || ..|||||..|.||.|.||||.|. . .|..
ekfpeelvlwlrdpldvrppllelldellllldlryalldedllpggEsladvaaRvlaaleellaralkpgknvlvVsHggvirallayllglpleeil
YLKCPLHTVIKLTPVAYGCR
.|..| . |..|. .. .
rlnipngsvtvlelddglvs
|
|||||||||
0050036 | Phosphoglycerate mutase-like | 280-452 | 7.4e-42 | 134.8 | In-house | 2-165 (171) | alignment | ||
Range on Protein: 280-452
Range on HMM: 2-165/171.0
TIYLTRHGESMHNQNGRIGG--DANLSERGWSYSRSLGEYMstqnlQDLKVWTSRLKRTVQTASSIDVAIEQWKSLDELDAGVCDGLTYEEIQKGHPEef
..|| ||||...| .||. | | .|.|.|. . | |||.. . |..| |.|..||| | . ..... | |.| |...|||..||.. .||
rlyLvRHGetewnlegrfqgwtdvpLtelgraqaralgell.....pfdavysSpllRArqTaelillpvivdprLrErdfGawegltldeiaakype..
alRDQDKFHYRYPMGESYQDLVARLEPVIMELErqKNVLVICHQGVMRCLLAYFLDKNSDELPYLKCPLHTVIKL
...|......| |||..|..||. |.. || .||||..|.||.|.|||..|. . .|...|..| ..|. |
..wlldlldlappggEsladvlaRvlpaleell..gnvlvvaHggvirallalllglsleeilrlelpngsvlvl
|
|||||||||
His_Phos_1 | Histidine phosphatase superfamily (branch 1) | 280-427 | 8e-38 | 122.8 | Pfam-A | 1-158 (158) | alignment | ||
Range on Protein: 280-427
Range on HMM: 1-158/158.0
TIYLTRHGESMHNQNGRIGGDAN--LSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSIDV----AIEQWKSLDELDAGVCDGLTYEEIQKGH
..||.||||| .|..||. |. . |.|.|. |.||.... ..|. .|.||.|||..||| .. |.. . | |.|.|...||..||... .
rlylvRHGesewnkegrlqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeilleeldipiikeprLrerdfgeweglpkeevkeef
PEEFALRDQDKFHYRYPMGESYQDLVARLEPVIMELE----RQKNVLVICHQGVMRCL
|||.. ...||...|.| |||..|...|..|...|| ...|||...|.||.|.|
peeyekwkrdkkefrppegesladvyeRvapfleelieakdkgenvlivsHggvlral
|
|||||||||
His_Phos_1 | Histidine phosphatase superfamily (branch 1) | 280-427 | 8e-38 | 122.8 | In-house | 1-158 (158) | alignment | ||
Range on Protein: 280-427
Range on HMM: 1-158/158.0
TIYLTRHGESMHNQNGRIGGDAN--LSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSIDV----AIEQWKSLDELDAGVCDGLTYEEIQKGH
..||.||||| .|..||. |. . |.|.|. |.||.... ..|. .|.||.|||..||| .. |.. . | |.|.|...||..||... .
rlylvRHGesewnkegrlqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeilleeldipiikeprLrerdfgeweglpkeevkeef
PEEFALRDQDKFHYRYPMGESYQDLVARLEPVIMELE----RQKNVLVICHQGVMRCL
|||.. ...||...|.| |||..|...|..|...|| ...|||...|.||.|.|
peeyekwkrdkkefrppegesladvyeRvapfleelieakdkgenvlivsHggvlral
|
|||||||||
AAA_33 | AAA domain | 59-168 | 9.3e-12 | 35.5 | Pfam-A | 1-98 (143) | alignment | ||
Range on Protein: 59-168
Range on HMM: 1-98/143.0
VIVMVGLPARGKTYIAKKLARYLNWIGINTKVfnvgeyRRKAVSGeishdfFRHDNAEAYKIRLQCAKEALEDMANWLDEDGEVAVFDATNTTRDRRQTI
....||||. ||.. |..|.. | .. ... . |... | ... . | .|. . ..|...| . ..| ...||||..|..|. .
lvllvGlpGsGKstlaerllkklgyvrlsqdt......lrrrlfg......tdqqsltdytrvlkrlyqilnklarkalsagrsvivdatnlsreerarf
LEFLGERHIK
.... . . .
vklakrlgvp
|
|||||||||
subfamily_TIGAR_pd | Subfamily TIGAR | 281-432 | 1.1e-11 | 36.8 | In-house | 3-174 (222) | alignment | ||
Range on Protein: 281-432
Range on HMM: 3-174/222.0
IYLTRHGESMHNQNGRIGGD--ANLSERGWSYSRSLGEYMSTQNLQdlKVWTSRLKRTVQTASSI--------DVAIEQWKSLDELDAGVCDGLTYEEIQ
... ||||.. |... . | |||.| .... .| .... . .| |.|. |||. | . |.|. | | | . || | ...|..
livVrhGetefnkekilqgqtdtpLsekGveQakrvakrLsnekin..yifsSdllRAkqTaeiilkalkekkreaverdkrLrEreyGvyeGvaldelr
KGHPEEFalrdqdKFHYR-YPMGESYQDLVARLEPVIMEL-----ERQ------------KNVLVICHQGVMRCLLAYFL
. . ... . ||| . | .|| . . || ... .|||..|. ..| ||....
ellkaag......nvpsfvpegGesieqlelrlvaaleelcakilhleadkkkdgaegelthvlvvshglalrellnvlh
|
|||||||||
subfamily_PGAM_pd | Subfamily PGAM | 280-347 | 1.7e-11 | 35.9 | In-house | 2-71 (248) | alignment | ||
Range on Protein: 280-347
Range on HMM: 2-71/248.0
TIYLTRHGESMHNQNGRIGG--DANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSIDVAI
.. | ||||| .|.. .. | ||.|||.| . . .|... .||. .|.||.|||..||.. | ..
klvllRhGeselnkenkfcgwvDakLsekGkeeAkkagkalkqanlefdivytSvlkRaqqTlevileel
|
|||||||||
AAA_17 | AAA domain | 59-168 | 1.8e-10 | 32.3 | Pfam-A | 1-91 (121) | alignment | ||
Range on Protein: 59-168
Range on HMM: 1-91/121.0
VIVMVGLPARGKTYIAKKLARYLNWIgintkVFNVGE-YRRKAVSgEISHDFFrhdnaEAYKIRLQCAKEALEDMANwlDEDGEVAVFDAtnttrdrrqt
||. .| |. ||...||.||..|... |.. .. .|.... |. .... |.. . .. .. |...|. .|... |.|
viaitGppGsGKsTlakeLaerlglp.....vlslddllreeglk.elddger.....eskdadadllaaildglaa..kkdtlswvidg..........
ileflgE---------RHIK
...
......aleveldlrleead
|
|||||||||
subfamily_TFC7_pd | Subfamily TFC7 | 280-425 | 5.6e-08 | 23.6 | In-house | 2-171 (255) | alignment | ||
Range on Protein: 280-425
Range on HMM: 2-171/255.0
TIYLTRHGE-------SMHNQNGR-IGGDANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSI----------DVAIEQWKSLDELDaGVC
|||..||| ... . | |. ||||| .. |..|... .|. . .| |.| ..|. .| | . .| |. .
tiyiarhGyrsnwlpkgpypdpltgidsdvPlserGveqakelaiylkkldlkpeaifssPlyrcletskpiaeeleiPvyvdrGvgewykpdrrP.vil
DGLTYEEIQKGHPEEFAlRDQDKFHYRYPMGESYQDLVARLE---PVIM-----ELERQKNVLVICHQGVMR
. ...|...| .|. .| . . ||. ..| |.. || . . . .. .|.. | .
ePasnevlskffPsvis.ldyestltpsekgeteeelyertkkfwpvfidrvekkfknvetilivthaatki
|
|||||||||
subfamily_STS_pd | Subfamily STS | 298-427 | 1.4e-07 | 23.2 | In-house | 50-193 (245) | alignment | ||
Range on Protein: 298-427
Range on HMM: 50-193/245.0
GGDANLSERGWSYSRSLGEYMSTQNLQDLKVWTSRLKRTVQTASSIDVAIEqWKSLDELDAGVCDGLTYEEIQ-K--GHPE---EFALRDQDKF---HYR
| |.||| .. ||.... .... .. | |..|||. | ... | ... |... | ... . . .|| .| .. . .. .
ksDpPlterGviqAkllgraLleagikiehifcSPslrciqTaaailkglg.kkikikvepgllewlkldrkpipellspeelkkffpqidedYkpvlsl
YPM--GESYQDLVARLEPVIMEL----ERQKNVLVICHQGVMRCL
... .||...|..| . |. |. ....|.|.. | . |
selkskeseeelyeRikkvvkeiiekvpedgniliVahaatldal
|
|||||||||
0053031 | Phosphoglycerate mutase-like | 279-343 | 2.8e-07 | 23.3 | In-house | 5-87 (342) | alignment | ||
Range on Protein: 279-343
Range on HMM: 5-87/342.0
RTIYLTRHG----ESMHNQNGRI-----GGDANLSERGWSYSRSLGEYMSTQ---------NLQDLKVWTSRLKRTVQTASSI
..|.|.||| .|... . .. |. |...|. .. ||... . | ....|..| ||.|.| ..
qvivlvRHGaRtPlskgpldplnewfypcgageLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdRtlqSAqaf
|
|||||||||
0049059 | Phosphoglycerate mutase-like | 279-343 | 1.1e-06 | 21.0 | In-house | 45-143 (435) | alignment | ||
Range on Protein: 279-343
Range on HMM: 45-143/435.0
RTIYLTRHGE--------------------SMHNQNGR---------IGGDANLSERGWSYSRSLGEYMST-----QNLQDLKVWTSRLKRTVQTASSI
....|.|||. .... || . |. |...|. . ||... | ....|..| ||.|.| .
qvqvlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrYgfLynpdevyvrssdvdRtlqSaqaf
|
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KTI12 | Chromatin associated protein KTI12 | 59-114 | 5.4e-06 | 15.7 | Pfam-A | 3-51 (270) | alignment | ||
Range on Protein: 59-114
Range on HMM: 3-51/270.0
VIVMVGLPARGKTYIAKKLARYLNWIGINTKVFNVGEYRrkavsgeISHDFFRHDN
.|. |||. ||. .||.||..|. |.. | . ... |..| ... .
LvvltGlPssGKstvakeLakaleeegrsvvvisdeslg.......iekdsykdsk
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0047369 | Phosphoglycerate mutase-like | 280-342 | 7e-06 | 18.6 | In-house | 47-143 (438) | alignment | ||
Range on Protein: 280-342
Range on HMM: 47-143/438.0
TIYLTRHGE----------------SMHNQNGRIGGD-------------ANLSERGWSYSRSLGEYMSTQ----NLQDL-KVWTSRLKRTVQTASS
...|.|||. . | .....|. |...|. . ||... . | .|. .|..| ||.|.| .
vqvlfRHGaRtPtksklkkleplwellenattypsgplsflndwlgpcgagqLTplGreqayelGkrlrkrYglLnpedvlyvrssdvdRtlqSAqa
|
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AAA_28 | AAA domain | 60-146 | 9.1e-06 | 12.1 | Pfam-A | 2-79 (163) | alignment | ||
Range on Protein: 60-146
Range on HMM: 2-79/163.0
IVMVGLPARGKTYIAKKLARYlnwigiNTKVFnvGEYRRKAVSGEIshdFFRHDNAE----AYKIRLQCAKEALEDMANWldEDGEVAVFD
||..| | ||| ....||.. ...|. |. |. .. . . ...... . ...... ...||. |. ..... ..|
ivitGgpstGKTtlleaLaar......gypvv..pEvarevleekl...akgeealpweedllafaeavleaqleqeaaa..aaskllfcD
|
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subfamily_PGAM_pd | Subfamily PGAM | 383-438 | 9.8e-06 | 17.0 | In-house | 141-200 (248) | alignment | ||
Range on Protein: 383-438
Range on HMM: 141-200/248.0
DKFHYRYPMGESYQDLVARLEPVIME-----LERQKNVLVICHQGVMRCLLAYfLDKNSDE
.. . ..| || ...|.||.||. | ....|.||.. | ...|.|| . |.. |||
elkeeelPesEslkevveRllpvlneeilkeikegkrvlivahgnsvrallkv.legisde
|