Gene STS in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily STS
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP170_AA protein Get Run
SpurP170_AA_386-628 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_STS_pd Subfamily STS 389-637 1.1e-94 308.4 In-house 1-244 (245) alignment 
Range on Protein: 389-637
Range on HMM: 1-244/245.0
RRLFIIRHGERVDVTFGEqWLIhCFDqQGKYQRKNLNMPKRVPQRPGGGQDFKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVLQ
|...|.|||||||..||. ||  .|| .|||.||.||.||..|.||.| .|.|.|.|.||.||.||...|.||  |||||.....|||||| |||.|.|.
rtiyivRhgeRvdevfgk.Wlk.sfd.egkyerkdlnlpkelprrpdglkdyksDpPlterGviqAkllgraLleagikiehifcSPslrciqTaaailk

GLEapDAVKICVDTALFEWLAWCKGGLPKWLSPAELATFGLNIDLSYKEKLTPSDLNQKENCQAYYKRSENFVREVLKECSDDGDILLVGHASTLDSSSR
||.  ...||.|...|.|||..... .|..||| ||..|...||..||. |..|.|..||.....|.|....|.|.......||.||.|.||.|||..||
glg..kkikikvepgllewlkldrkpipellspeelkkffpqidedYkpvlslselkskeseeelyeRikkvvkeiiekvpedgniliVahaatldalsr

CLQGLSARPAMEFSRIVQKVPYCGIIMLEEYAEFSIWDLVAPIIPTLTH
.|.|||.| .......|.|.|||.. .|||..| . |.|... |. |..
qllglspresedlkklvikspycslakleenkeerkwkltdsgilsllk
subfamily_Cele-STS-like_pd Subfamily Cele-STS-like 391-617 1.1e-41 133.7 In-house 2-210 (229) alignment 
Range on Protein: 391-617
Range on HMM: 2-210/229.0
LFIIRHGERVDVTFGEqWlIHCFDQQGKYQRKNLNMPKRVPQRPgggQDFKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVLQGL
...||..||||  ||. | |. .| ..||.  ..|.|| .|.|.   . .| |.|.|||| ......| ||. .||..|  . || ||. |||...|.||
vvvirsaervdevfgk.W.iksadletkyrpldinvPkelpkra...ksykldpPlteiGkiaskligRaLrdrgiepsvvFCSPdlrsvqtaalllkgl

EApDAVKICVDTALFEwlawCKGGLPKWLSPAELATFGLNIDLSYKEKltpSDLNQKENCQAYYKRSENFVREVLKECSdDGDILLVGHASTLDSSSRCl
     ..| |. .|.|     .   ...|.| ..  .|  .|  ||      .| ..|. . ...|........|...  .. ||.| .. .|. . |  
Gl.kraaisvePgLle....yrkarevllppkafkklgypvdekYkPl...kelsmaeslsdfvariqaafkkllskve.qklilvvadnvsleltrre.

qglSARPAMEFSRIVQKVPYCGIIMLE
     . . ... ...| |.. . ...
...dvesvddllvllkktpalsvvivn
0036777 Phosphoglycerate mutase-like 388-627 3.8e-32 104.2 In-house 2-226 (247) alignment 
Range on Protein: 388-627
Range on HMM: 2-226/247.0
PRRLFIIRHGERVDVTfgeqwlihcfdqqgkyqrknlnmpkrvpqrPGGGQDFkKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVL
..||...|||| .. .                               |  |.   |.|.|| |. ||. .||.|| .|... ..|.|| ||. |||...|
mkrlyLvRHGetewna..............................egrfqgw.lDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiil

QGLEAPdAVKICVDTALFEW---------------------LAWCKGGLPKWLSPAELATFGLNIDLSYKEKLTPSDLNQKENCQAYYKRSENFVREVLK
..|. .  ... || .| |.                      ||. . .. .  . || .  |..|| .   |.   | . |. .....| .....|.| 
ealgls.llpvvvdprLrErdyGalegltkaeiaekypeelvawwrdpydyrppllelllelllldllryallpldllpggEsladvvaRvlpaleella

EC-SDDGDILLVGHASTLDSSSRCLQGLSARPAMEFsrivqKVPYCGIIMLEEYAEFSIWDL
..  |....|.|.|. .| .  . | |||   ....     ..|...|. ||  ..  .| |
rllkdgenvlvVsHggvlrallayllglsledilrl.....nlpngsitvleldddgklwvl
0051064 Phosphoglycerate mutase-like 388-628 3.6e-31 101.3 In-house 3-228 (241) alignment 
Range on Protein: 388-628
Range on HMM: 3-228/241.0
PRRLFIIRHGERVDVTFGEQWLihcfdqqgkyqrknlnmpkrvpqrpgggqdfKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVL
..||...||||... . |  .                                  |.|.|| |. |||..||.|...|||....|.|| ||. |||....
mkrlyLvRHGesewnaegrlqg...............................wtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiia

QGLEAPdAVKICVDTALFEWLAWCKGGLPKWLS----PAELATFGLNIDLSYKEKLTPSDL-----------------NQKENCQAYYKRSENFVREVLK
..|  |  ... || .| |.   .  ||...      | ||. .  .    .   |...||                    |. .....| .....|.| 
ealglp.llpvvvdprlrEidfgalegltleeiaekfpeelvawlrdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleella

E-CSDDGDILLVGHASTLDSSSRCLQGLSARPAMEFsrivqKVPYCGIIMLEEYAEFSIWDLV
.   |....|.|.|. .. .  . | ||.   .. .     ..|..... ||  .... . ||
rllldgknvlvVsHggvirallayllglpleellrl.....nlpngsvtvleldddgkrvvlv
0048955 Phosphoglycerate mutase-like 390-628 1.2e-30 99.5 In-house 2-225 (240) alignment 
Range on Protein: 390-628
Range on HMM: 2-225/240.0
RLFIIRHGERVDVTFGEQWLihcfdqqgkyqrknlnmpkrvpqrpgggqdfKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVLQG
||...||||... ..|  .                                  |.|.|| |. |||..||.|...|||....|.|| ||. |||......
rlyLvRHGesewnaegrlqg...............................wtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaea

LEAPDaVKICVDTALFEWLAWCKGGLPKWLSPAELATFGLNIDLSYKE---------------------KLTPSDLNQKENCQAYYKRSENFVREVLKEC
|  |  ....|| .| |.  ..  ||..    ...  .   .  .                        .|... |   |. .....| .....|.|...
lglpl.lpvvvdprlrErdfgalegltldeiaekfpeelvlwlrdpldvrppllelldellllldlryalldedllpggEsladvaaRvlaaleellara

S-DDGDILLVGHASTLDSSSRCLQGLSARPAMEFsrivqKVPYCGIIMLEEYAEFSIWDLV
  .....|.|.|. .. .  . | ||. . ....     ..|..... || . ..  .. .
lkpgknvlvVsHggvirallayllglpleeilrl.....nipngsvtvlelddglvslndt
0043909 Phosphoglycerate mutase-like 388-621 2.3e-30 98.2 In-house 2-224 (249) alignment 
Range on Protein: 388-621
Range on HMM: 2-224/249.0
PRRLFIIRHGERVDVTFGEQwlihcfdqqgkyqrknlnmpkrvpqrpgggQDfKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVL
..||...|||| .. . |                                |.   |||.|| |. |||..|||||..||.....|.|| .|. |||...|
mkrlyLvRHGetewnaegrf..............................qg.wlDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiil

QGLEAPDaVKICVDTALFEW------------------------LAWCKGGLPKWLSPAELATFGLNIDLSYKE-KLTPSDLNQKENCQAYYKRSENFVR
..|. .  ... || .| |.                        |..  . || .|..  .  . |..|. ...  .    ... |. .....| .....
eelgldk.lpvevdprLrErdfGalegltkaeiaekypeelvawlrrsydvlpplleeldelllellldyaladldplldrppggEsladvvaRvlpale

EVLKEC-SDDGDILLVGHASTLDSSSRCLQGLSARPAMEFsrivqKVPYCGIIMLEEYAE
|.|...  |.|..|.|.|. .| .  . | ||| . ....     ..|...|. ||  ..
ellarllkdggnvliVaHggvlrallayllglsledilrl.....nlpngsitvlelddg
0037864 Phosphoglycerate mutase-like 387-620 2.8e-28 91.2 In-house 6-199 (211) alignment 
Range on Protein: 387-620
Range on HMM: 6-199/211.0
QPRRLFIIRHGERVDVTFGEQWlihcfdqqgkyqrknlnmpkrvpqrpggGqdfKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAV
...||...||||... . |  .                            |     |.|.|| |. |||..||||. .|......|.|| ||. |||...
lmtrlyLvRHGetewnaegrlq............................g...wldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeii

LQGLEAPdAVKICVDTALFEWLAWCKGGLPKWLSPAELATFGLNIDLSYKEKLTPsdlnQKENCQAYYKRSENFVREVLKEC-SDDGDILLVGHASTLDS
|..|  |  ... || .| |.  .   ||..    ..       .  ..     |    . |. .....| .....|.|... .|....|.|.|. .| .
lealglp.llpvevdprlrErdfgalegltleeiaekypeelvawlrdpydfrpp....ggEsladvvaRvlpaleellarllkdgenvlvVsHggvlra

SSRCLQGLSARPAMEFsrivqKVPYCGIIMLEEYA
  . | |||   ....     ..|..... ||   
llayllglsleellrl.....nlpngsvtvleldd
His_Phos_1 Histidine phosphatase superfamily (branch 1) 390-585 1.2e-27 89.8 Pfam-A 1-157 (158) alignment 
Range on Protein: 390-585
Range on HMM: 1-157/158.0
RLFIIRHGERVdvtfgeqwlihcfdqqgkyqrknlnmpK----RvpqrPGGGQDfkkdSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHA
||...||||..                                |      | .|    .|.|| |  ||| .|..||.|...|. .|.||..|. |||..
rlylvRHGese...........................wnkegr....lqgwsd....vpLtekGreqarelgkkLkradlpidavytSplkRaiqTaei

VLQGLEapdaVKICVDTALFEWLA-WCKgGLPKWLSPAELATFGLNIDLSYKEKLTPsdlnQKENCQAYYKRSENFVREVLKECSDDGDILLVGHASTLD
.|..|.    ..|. . .| |. .  .. ||||.  ..|.     ...  .||   |    ..|. ...|.| ..|..|.... ......|.|.|...|.
lleeld....ipiikeprLrerdfgewe.glpkeevkeefpeeyekwkrdkkefrpp....egesladvyeRvapfleelieakdkgenvlivsHggvlr

S
.
a
His_Phos_1 Histidine phosphatase superfamily (branch 1) 390-585 1.2e-27 89.8 In-house 1-157 (158) alignment 
Range on Protein: 390-585
Range on HMM: 1-157/158.0
RLFIIRHGERVdvtfgeqwlihcfdqqgkyqrknlnmpK----RvpqrPGGGQDfkkdSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHA
||...||||..                                |      | .|    .|.|| |  ||| .|..||.|...|. .|.||..|. |||..
rlylvRHGese...........................wnkegr....lqgwsd....vpLtekGreqarelgkkLkradlpidavytSplkRaiqTaei

VLQGLEapdaVKICVDTALFEWLA-WCKgGLPKWLSPAELATFGLNIDLSYKEKLTPsdlnQKENCQAYYKRSENFVREVLKECSDDGDILLVGHASTLD
.|..|.    ..|. . .| |. .  .. ||||.  ..|.     ...  .||   |    ..|. ...|.| ..|..|.... ......|.|.|...|.
lleeld....ipiikeprLrerdfgewe.glpkeevkeefpeeyekwkrdkkefrpp....egesladvyeRvapfleelieakdkgenvlivsHggvlr

S
.
a
0036887 Phosphoglycerate mutase-like 388-618 8.5e-27 86.5 In-house 1-185 (202) alignment 
Range on Protein: 388-618
Range on HMM: 1-185/202.0
PRRLFIIRHGERVDVTFGEQW--LihcfdqqgkyqrknlnmpkrvpqrpgggqdfkkDSPITEIGVYQARMTGEALKaaGIKISYCYASPSLRCSQTAHA
..||...||||... . |     |                                 |.|.|| |. |||..||.|.  |... ..|.|| ||. |||..
mtrlyLvRHGetewnvegrlqgdl.................................dvpLtelGreqaralgerla..glpfdavysSpllRaiqTaei

VLQGLEapdaVKICVDTALFEWLAWCKGGLPKWLSPAELATFGLNIDLSYKEKLTPsdlnQKENCQAYYKRSENFVREVLKECsDDGDILLVGHASTLDS
....|.    ....|| .| |.  ..  ||..    ..   .   .  ..     |    . |. .....| .....|.|... |.|..|.|.|. .|  
iaealg....lpvivdprlrEidfgalegltleeiaekypeelaawlrdpydfrpp....ggEsladvvaRvlaaleellarl.dggnvlvVsHggvlra

SSRCLQGLSARPAMEFSrivqKVPYCGIIMLEE
  . | |||   .. .     |.|..... || 
llayllglsledllrlr....klpngsvtvlel
0035570 Phosphoglycerate mutase-like 390-622 4e-26 84.3 In-house 1-179 (219) alignment 
Range on Protein: 390-622
Range on HMM: 1-179/219.0
RLFIIRHGERVDVTfgeqwlihcfdqqgkyqrknlnmpkrvpqrP---GGgqdfkkDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAV
||...||||... .                              .    |      |.|.|| |. |||..||||.. ||.. ..|.|| ||. |||...
rlyLvRHGetewnl..............................egrlqg......dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii

lqgleapdAVKICVDTALFEWLAWCKGGLPKWLSPAELATFGLNIDLSYKEKLTpsdlNQKENCQAYYKRSENFVREVlkecSDDGDILLVGHASTLDSS
         .....| .| |. .    ||..    ..       .  .          .. |. .....| .....|.     |....|.|.|. ..   
........glpveidprLrEidfgdlegltldeiaekypeelaawlrdpydyrp....pggEsladvvaRvlpaleel....edgenvlvVsHggviral

SRCLQGLSARPAMEFSrivqkVPYCGIIMLEEYAEF
 . | ||..  .. ..     .|..... ||  .. 
layllglpleeilrln.....lpngsvtvleldggg
0049178 Phosphoglycerate mutase-like 388-618 1.5e-25 82.7 In-house 3-216 (243) alignment 
Range on Protein: 388-618
Range on HMM: 3-216/243.0
PRRLFIIRHGERVD----VTFGeqwlihcfdqqgkyqrknlnmpkrvpqrpgggqdfKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTA
..||...|||| .     .  |                                     ||| || |. ||| .||.|...|.|. ..|.|| .|. |||
mtrlyLvRHGetewnaegrlqg...................................wtDspLtelGreqAralgellaelglkfdavysSplkRaiqTa

HAVLQGLEAPDaVKICVDTALFEW---------------------LAWCKGGLPKWLSPaeLATFGLNIDLSYKEKLTPSDLNQKENCQAYYKRSENFVR
...|..|  |  ... || .| |.                      ||  . .  .  .  | ...| ..| .   .    | . |. .....| .....
eiilealglpl.lpvvvdprLrErdfGalegltkaeiaakypeelvawwrdpydarppa..lllldlllplldrlladldllpggEsladvaaRvlpale

EVLKEC-SDDGDILLVGHASTLDSSSRCLQGLSARPAMEFSrivqkVPYCGIIMLEE
|.|.|.  |....|.|.|  .. .  . | ||.   .. .      .|..... || 
ellaellhdgktvlvVaHggvirallalllglpleellrln.....lpngsvtvlel
0039931 Phosphoglycerate mutase-like 390-620 1.9e-24 78.7 In-house 1-177 (219) alignment 
Range on Protein: 390-620
Range on HMM: 1-177/219.0
RLFIIRHGERVDVTfgeqwlihcfdqqgkyqrknlnmpkrvpqrP---GGgqdfkkDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAV
||...|||| .. .                              .    |      |||.|| |. ||| .||.||  |... ..|.|| ||. |||...
rlyLvRHGetewnv..............................egrlqg......dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii

lqgleapdAVKICVDTALFEWLAWCKGGLPKWLSPAELATFGLNIDLS-----YkekltpsdlNQKENCQAYYKRSENFVREVLKecsdDGDILLVGHAS
         .....| .| |. .    ||..    ..       .  .     .         .. |. .....| .....|.|.    ....|.|.|. 
........glpveidprLrEidfgdlegltleeiaekypeelaawlrdpydyrp.........pggEsladvvaRvlpaleella....genvlvVsHgg

TLDSSSRCLQGLSARPAMEFsrivqKVPYCGIIMLEEYA
..    . | |||   .. .     ..|..... || ..
virallayllglsleeilrl.....nlpngsvtvleldd
0053607 Phosphoglycerate mutase-like 439-618 1.6e-20 65.9 In-house 22-177 (191) alignment 
Range on Protein: 439-618
Range on HMM: 22-177/191.0
DfkkDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVlqgleapdAVKICVDTALFEWLAWCKGGlpkwLSPAELATFGLNIDLSYKEK
    |.|.|| |. ||| ..|.|.. |.|. ..|.|| ||. |||...         ... || .| |. .    |    |. .|||    ..   . . 
g...dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii........glpvevdprlrEidfgdweg....ltleelaekypeelaawlrd

LTPSDLNQKENCQAYYKRSENFVREVLKecsdDGDILLVGHASTLDSSSRCLQGLSARPAMEFSrivqkVPYCGIIMLEE
      .. |. .....| .....|.|.    .|..|.|.|. ..    . | ||.   .. ..     .|..... || 
pldyrppggEsladvaaRvlpaleella....ggnvlvVaHggvirallayllglpleellrln.....lpngsvtvlel
0050036 Phosphoglycerate mutase-like 442-600 6.7e-16 50.6 In-house 23-154 (171) alignment 
Range on Protein: 442-600
Range on HMM: 23-154/171.0
KDSPITEIGVYQARMTGEALkaagiKISYCYASPSLRCSQTAHAVLqgleapdaVKICVDTALFEWLAWCKGGLPKWLSPAELATfglnidlsYKEKLTP
 |.|.|| |. ||| .||.|     .. ..|.|| ||. |||...|        ... || .| |.      ||..   .|.           .   |  
tdvpLtelgraqaralgell.....pfdavysSpllRArqTaelil........lpvivdprLrErdfGawegltldeiaakype........wlldlld

SDLNQKENCQAYYKRSENFVREVLkecsddGDILLVGHASTLDSSSRCLQGLSARPAME
  . . |. .....|  ....|.|      |..|.|.|. .. .  . | |||.  ...
lappggEsladvlaRvlpaleell......gnvlvvaHggvirallalllglsleeilr
subfamily_TFC7_pd Subfamily TFC7 438-590 1.6e-15 48.4 In-house 25-177 (255) alignment 
Range on Protein: 438-590
Range on HMM: 25-177/255.0
QDFKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVLQGLEAPdavkICVDTALFEWLAWC-KGGLPKWLSPAELATFGLN-IDLSY
.  ..| |..| || ||.  .. ||  ..|    ..||  || .|.... . || |    . ||  . ||.    .  ... .|  .|  |  . |.| |
tgidsdvPlserGveqakelaiylkkldlkpeaifssPlyrcletskpiaeeleiP....vyvdrGvgewykpdrrPvilePasnevlskffPsvisldy

KEKLTPSdlNQKENCQAYYKRSE----NFVREVLKECSDDGDILLVGHASTLDSSSRCL
.  ||||  ...|  .  |.| .     |. .| |.  ... ||.| ||.|  .  . |
estltps..ekgeteeelyertkkfwpvfidrvekkfknvetilivthaatkialGmsl
SH3_9 Variant SH3 domain 247-301 1e-14 43.1 Pfam-A 1-49 (49) alignment 
Range on Protein: 247-301
Range on HMM: 1-49/49.0
VLYGHTPRVPDELELIPDDFVYMSaTEldkNSDGWFKGTShkTGCEGMFPGNYTE
.|| ..|. .|||.| ..|.....  |    .|||. |..  ||. | .| ||.|
AlydyepkdddELslskGdvitvl.ee...tedgWllGel..tGrtGlvPanyVe
subfamily_TIGAR_pd Subfamily TIGAR 440-507 1.2e-11 36.7 In-house 21-86 (222) alignment 
Range on Protein: 440-507
Range on HMM: 21-86/222.0
FKKDSPITEIGVYQARMTGEALKAagIKISYCYASPSLRCSQTAHAVLQGLEAPDAVKICVDTALFEW
.. |.|..| || ||  ... |..   || | ..|. ||  |||...|. |.. .  .. .|  | |.
gqtdtpLsekGveQakrvakrLsn..ekinyifsSdllRAkqTaeiilkalkekkreaverdkrLrEr
0047369 Phosphoglycerate mutase-like 392-521 2.2e-11 36.7 In-house 49-164 (438) alignment 
Range on Protein: 392-521
Range on HMM: 49-164/438.0
FIIRHGERVD----VTfGEQWLIHCFDQQGKYQRKNLNMPKRVPQRPGGGQdfkkdspITEIGVYQARMTGEALKAA----GIKIS-YCYASPSLRCSQT
 ..|||.|         ....|. .... . | . .|.. ....   | ||        |. |..||.. |. | .       .   | ..|.. |. |.
vlfRHGaRtPtksklk.kleplwellenattypsgplsflndwlgpcgagq.......LTplGreqayelGkrlrkrYglLnpedvlyvrssdvdRtlqS

AHAVLQGLEAPDAVKICVDTALFewlawckgglpkwlsP
| |.|.||  |.  ..  .  .                |
AqaflaGlfppegtgelapilwq...............p
0053031 Phosphoglycerate mutase-like 391-503 3.1e-11 36.3 In-house 7-116 (342) alignment 
Range on Protein: 391-503
Range on HMM: 7-116/342.0
LFIIRHGERV-----DVTFGEQWLIhcfdqqgkyqrknlnmpkrvpqrpgggqdfKKD-SPITEIGVYQARMTGEALKAA---------GIKISYCYASP
 ...|||.|      ....  .| .                              . . .. |. |..||...|..|.             .. | ..|.
ivlvRHGaRtPlskgpldplnewfy..............................pcgageLTplGreqayelGrrlrkrYlgllpstynpdevyvrssd

SLRCSQTAHAVLQGLEAPDAVKI------------CVDTA
. |. |.| |.|.||  |.  .|             .  .
vdRtlqSAqaflaGlfppegtpilnpllgwqpipihtepe
0049059 Phosphoglycerate mutase-like 392-507 4e-11 35.6 In-house 48-152 (435) alignment 
Range on Protein: 392-507
Range on HMM: 48-152/435.0
FIIRHGERV---DVTFGEQWLIHCFDQQGKYQRKNLNMPKRVPQRPGGGQdfkkdspITEIGVYQARMTGEALKA-----AGIKISYCYASPSLRCSQTA
 ..|||.|     .  . . |.... .   | . .|.. . ..   | |.        |. |..||...|. | .        .  | ..|.. |. |.|
vlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgage.......LTplGreqayelGkrlrkrYgfLynpdevyvrssdvdRtlqSa

HAVLQGLEAPDavkicvdtalfeW
 |.|.||  |.            .
qaflaGlfppe............i
0048946 Phosphoglycerate mutase-like 392-566 2.3e-10 33.0 In-house 46-200 (447) alignment 
Range on Protein: 392-566
Range on HMM: 46-200/447.0
FIIRHGERV---DVTFGEQWLIHCFDQQGK-YQRKNLNMPKRVPQRPGGGQDFK--KdSPITEIGVYQARMTGEALKAA------GIKISYCYASPSLRC
 ..|||.|    ....| ..|. ......  . ...|..... .  .. .  .     .  |. | .|... |..|.          .  | ..|.. |.
vlfRHGaRtPtkkylkgleplldllknanvlelggdlsflndwkyqlkneplwpcgl.gqLTplGreqlyelGkrlrkrYlgllpnpseiyvrssdvdRt

SQTAHAVLQGLEAPDavkicvdtalfewlawckgglpkwlspaelatfglnidL--SY--------KEKLTPSDLNqkeNCQAYYKRSENFVREVLK
 |.| |.|.||  |.                                      .  .|        ..   .. |.   .|.|...   ... | ||
lqSaqaflaGlfppe......................................pplgyqpipihtvpssndnlllp...sCpafkellkkelaeelk
0046349 Phosphoglycerate mutase-like 392-566 5.6e-10 32.1 In-house 12-170 (409) alignment 
Range on Protein: 392-566
Range on HMM: 12-170/409.0
FIIRHGERVDVTFgeqwlihcF-----------DqqgkyqrknlnmpkrvpqrpgggqDFKKD-SPITEIGVYQARMTGEALKA----AGI---------
...|||.|  .          .                                     .. . .. |. |..||...|..|..     |.         
vlfRHGaRtPtkk........lsflpnwpginwt........................ngpcgagqLTplGreqayelGkrlrkrYvdlgLlpsnslynp

KISYCYASPSLRCSQTAHAVLQGLEAPDAV----------------KICVDTALfewlawckgglpkwlspaelatfglnidLSYKEKLTPSDLNQKENC
.. | ..|.. |. |.| |.|.||  |. .                .| .||.                             .|. . |    |. . .|
deiyvrssdvdRtlqSAqaflaGlfpplggeivpllrqdlldppfqpipidtvp............................iseddalddtllppdslc

QAYYKRSENFV---REVLK
.|..|  ...    .|||.
paldkllkenlkslsevle
0049226 Phosphoglycerate mutase-like 392-502 6e-10 32.0 In-house 8-103 (342) alignment 
Range on Protein: 392-502
Range on HMM: 8-103/342.0
FIIRHGERVDVTFGE-----QWLihcfdqqgkyqrknlnmpkrvpqrpgggqdfkKD---SPITEIGVYQARMTGEALKA---------AGIKISYCYAS
..||||.|  . .|.     .|.                                 .   .. |. |..||.. |..|.             .. | ..|
vliRHGdRtPlakgpldflnewf................................wgcglgeLTplGreqayelGrrlrkrYlgllpstynpdevyvrss

PSLRCSQTAHAVLQGLEAPDAVKICVDT
.. |. |.| |.|.||  |.   |.|..
dvdRtlqSaqaflaGlfppeltpilvpl
0048439 Phosphoglycerate mutase-like 392-496 5.8e-08 25.6 In-house 14-112 (391) alignment 
Range on Protein: 392-496
Range on HMM: 14-112/391.0
FIIRHGERV---DVTFGEQWLIHCfdqqgkyqrknlnmpkrvpqrpgggqdF----KKD-SPITEIGVYQARMTGEALKAA-------------GIKISY
 ..|||.|    .... .. |...                           .    . . .. |. |..|.. .|..| .                .. |
vlfRHGaRtPtssypnkldpllnk...........................llpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevy

CYASPSLRCSQTAHAVLQGLEAPDAV
 ..|.. |. |.| |.|.||  |   
vrssdvdRtlqSAqaflaGlfpplgl
subfamily_PGAM_pd Subfamily PGAM 442-491 5.9e-08 24.3 In-house 23-72 (248) alignment 
Range on Protein: 442-491
Range on HMM: 23-72/248.0
KDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVLQGLE
.|  ..| |. .|. .|.||| |....  .|.|   |. ||....|. |.
vDakLsekGkeeAkkagkalkqanlefdivytSvlkRaqqTlevileeld
SH3_1 SH3 domain 246-296 3.6e-07 18.8 Pfam-A 1-47 (48) alignment 
Range on Protein: 246-296
Range on HMM: 1-47/48.0
RVLYGHTPRVPDELELIPDDFVYMSATELDknsdGWFKGTSHKTGCEGMFP
..||  ..| .||| . ..| ..  . . |    ||.|| ...|| ||..|
iAlYDYearesdELsfkkGDviivleksed....gWwkgrlkgtgkeGliP
UBA UBA/TS-N domain 29-59 5.6e-07 17.8 Pfam-A 8-37 (37) alignment 
Range on Protein: 29-59
Range on HMM: 8-37/37.0
LLMSMGFPKHRVEKAAAATGHqDIQLASDWL
 |. |||..... ||  ||.  ... | ..|
qLreMGfsreeakkALratnn.nverAveyL
2_5_RNA_ligase2 2'-5' RNA ligase superfamily 106-214 3.7e-06 15.4 Pfam-A 21-127 (153) alignment 
Range on Protein: 106-214
Range on HMM: 21-127/153.0
AHSLLPHVTLCSFITCPDSKctaltDAFQEVIDRWQ--TKAPEvLTLDFYSS---TNFiGLFLEDEHAEYLRKVMADFSVEAASRAGVKVEPHKKQLHLT
..   ||.||.   . |..      ....|.. |.   |.. | ..|| ...    .   ..||..  | |... |.   . .    .. . .. . |||
yprwppHiTLlypfvepedl.....qdlaellsrlaaetepfe.vrldgvgvFehkks.vvylevspseslsaLraallealpeaglkedstgeftPHlT

LAYQFNPTHQEPLV
.|.. ..| .. |.
iaqsedstsakell
LigT_PEase LigT like Phosphoesterase 166-212 8.2e-06 14.2 Pfam-A 6-52 (87) alignment 
Range on Protein: 166-212
Range on HMM: 6-52/87.0
EHAEYLRKVMADFSvEAASRAGVKVEpHKKQLHLTLAYQFNPThqE----P
| || |... |..  .|....|.|.. .. ..|.|||  .. .  |     
eiaeelarlaaele.ralaklglkpv.rpfnpHiTLaflgevd..eekvpe