Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PP2D1_pd | Subfamily PP2D1 | 159-776 | 8.1e-261 | 858.8 | In-house | 1-492 (492) | alignment | ||
Range on Protein: 159-776
Range on HMM: 1-492/492.0
RAVGICSDDNSRWKSKMEDTRVFQDYYGNDVNKCFFGIYDGYNGRFAADIAANDLHHVFLSELQKVDERVSCTCAVNLADNNDLTDYELERGSpivRSDS
.|||||.|.||||||||||.|..|||.|||||.|||||||||||..||.|||..||.|.|.||.|||||||.|.||||.||||||||||||.| ||||
kavGiCedknsrWKskmeDkrtlqdyfgndvnscFfgiyDGynGataAeiaakelhevlleelekvdervslttavnlidnndltdyeleras...rsds
IRHILHEESINiiqqimhtcesnlmkmsdivsqesvgdwptrkkknrdPEFEKVSQAYHMSYLYLDRYLSYGINETSLVRWSGCSALSLLINskeqleae
||.||.|||.. ||||||..|...|||.|||.|||||.|.|.|||||||||.||..
irailkeesvk.....................................pefekvkkAfrksylrldrlLsygieeesrvrWsGCsAltllle........
npGNKdentqtddgakdekkdRETEATEKEEKGDSEEGQEKESNGSEVHLEELGVLHIANAGNTQAVLCRAGKAYHLTRDHTPGNPQERTRVEKAGSSVH
||| |||||||||||.|||||.|||||||||||||||||.||||||.||||||.|||..|||.|||.|..||||||||||.|.
..Gnk................reteatekeekkdseeGlekesngsevhleelgvlyianaGnvqAvLcreGkaiiLtreHtprnkkERtRvekagsvvv
AGGPNGRVNGILDTTRGLGNYGDPHLKKAVIPEPYTTSVKIDQHAQFIVMASCGLWDVLTDDDVLSLVKQTLAIHQSRTQAENVPDeyegysrSDVTTYG
....||.|||||||||||||||||.|||.|||||.|||||.|..|||.|.||.|||.||....|||||||||||..||..|||||| |||||.|
kseknglvnGildttRGLGnyGdpkLkksvipePkttsvkldeaaqflvlAsnGlWevlseeevlsLvkqtlaiyksrvraenvpd.......sdvttvg
EDYLGESFATGLSASYEQTGFDNTVTSVIDIDAAEGDEANLQKKHFLNPLPSLKEDADDEDDGDDEANSKSEITWNEPLTDKGAEDHQEAPSNEGKSQNN
||||||..|..|||.||.||||..|||.||.|||||||.||||....|.|...|||||||..|..|||||.|||.||..|||.||...||.|.|.||.|.
edylgEleakklsaryentgfdkfvtseidldaaegdesnlqklfsynelsevkedaddereglseanskkeityneedtdksaeeskeaksseekstnr
GIRVEGVAEDVKAEIEEETVPDmknykeefndnastktdfesmlsalcddgneadietltelhtfyaksrlseglGIVDKKEEYRLAAEMISERLVQSAL
.||||.|||.||||.||||..| |||||||.|.||||..|||||||||
sirveevaenvkaekeeetksd.....................................................givdkkekyelaAealserlvqsAL
MAGSRDNITAMVILLHGC
.||||||||.|||||.||
lAGsrDnitvmvilLkGc
|
|||||||||
0034914 | PP2C-like | 158-775 | 5.3e-46 | 149.8 | In-house | 20-292 (295) | alignment | ||
Range on Protein: 158-775
Range on HMM: 20-292/295.0
VRAVGICSDDNSrwKSKMEDTRVFQDYYGN-DVNKCFFGIYDGYNGRFAADIAANDLHHVFLSELQKVDERVSCTcavnladnndltdyelergspivrs
. ||..|| . ....|| .. . . . . ..||..||..| ||..|.. |.. .|..|.|.. . .
llrvgvasdqGr..rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltls.........................
dsirhilheesiniiqqimhtcesnlmkmsdivsqesvgdwptrkkknrdpeFEKVSQAYHMSYLYLDRYLSYGINETSLVRWSGCSALSLLINSKeqle
.| . .|.. ..| .|..| . . . ...||..|. .|| ..
....................................................ledieealrkaflaadeellelallrpelagsGtTavvalirgn....
aenpgnkdentqtddgakdekkdreteatekeekgdseegqekesngsevhleelgVLHIANAGNTQAVLCRAGKAYHLTRDHTPGNPQERTRVEKAGSS
|..||.|...|||.| |....||.||.| |. || |...||
........................................................klyvanvGDSravllrngelvqltvdhkpvnelererilsagga
VHAggpnGRVNGILDTTRGLGNYGDP------HLKKAVIPEPYTTSVKID-QHAQFIVMASCGLWDVLTDDDVLSLVKQTLAIHQSrtqaenvpdeyegy
|. |||||.| || || . .|. .|..||..|..... .. .|...|| ||||||........|...|| ...
vsh....grvngvlavtRalGdfdlklllslllleplvsaePdvtvleltledddfllLasDGlwdvlsneeivdivrsllakgld..............
srsdvttygedylgesfatglsasyeqtgfdntvtsvididaaegdeanlqkkhflnplpslkedaddeddgddeanskseitwnepltdkgaedhqeap
....................................................................................................
snegksqnngirvegvaedvkaeieeetvpdmknykeefndnastktdfesmlsalcddgneadietltelhtfyaksrlseglgivdkkeeyrlaAEMI
.|..
................................................................................................leea
SERLVQSALMAGSRDNITAMVILLHG
.|.||. || .|||||||..|. |.|
aeeLvdlAlargsrDNiTvvvvrlng
|
|||||||||
PP2Cc_SM00332 | 166-533 | 4.9e-45 | 147.0 | In-house | 15-243 (274) | alignment | |||
Range on Protein: 166-533
Range on HMM: 15-243/274.0
DDNSRWKSKMEDTRVFQDYYGNDVNKCFFGIYDGYNGRFAADIAANDLHHVFLSELQKVDERVsctcavnladnndltdyelergspivrsdsirhilHE
... |...||| | . . . . |||..|| .| .|..... |.. . .||.|... ..
ssmqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel...................................ed
ESINIIQQIMHTCESNLMKMSDIVSQESvgdwptrkkknrdpefekvsqayhmsylyldrylsyginetslvRWSGCSALSLLINSKEqleaenpgnkde
. ..... . ........ . .| ||..|.. |.. .
dveealkkaflstdeeileeeqskelen............................................alsGstavvallkked............
ntqtddgakdekkdreteatekeekgdseegqekesngsevhleelgvLHIANAGNTQAVLCRAGKAYHLTRDHTPGNPQERTRVEKAGSSVHAGgpngR
|..||.| .|||||.||| |..||.| ...|| |..||| .|. | |
................................................lyvanvGDSravlcrngkavqlsvdhkpedederkRikkaggvvekg....r
VNGILDTTRGLGNYG----DPHLKKAVIPEPYTTSVKIDQHAQFIVMASCGLWDVLTDDDVLSLVKQTLAIH
||| | .| .| . ... .. ...|| .. |..... .|...|| ||||||....| ..|...||
vngglavsrafGdhflkknkklkepyitaepdvkvvtltsedeflilaSDGlwdvlsnqevvdivrkllakg
|
|||||||||
subfamily_PPM1A_pd | Subfamily PPM1A | 166-537 | 2.6e-41 | 134.8 | In-house | 17-254 (282) | alignment | ||
Range on Protein: 166-537
Range on HMM: 17-254/282.0
DDNSRWKSKMEDTRVFQDYYGNDVNKCFFGIYDGYNGRFAADIAANDLHHVFLSelqkvdervsctcavnladnndltdyelergspivrsdsirhilhe
. .. |...|||. . . |. .. || ..|| |. .|..... |.. |.
ssmqgwrvemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenile..............................................
esiniiqqimhtcesnlmkmsdivsQ----EsvgdwptrkKKNRDPEFEKVSQAYHMSYLYLDRYLSYGINETSLVRWSGCSALSLLINskeqleaenpg
. | .. .. | ..|..| . ..| || .. .... ||. |...|..
.........................eeelke.........aaleasekdevkealrqgfLaldeairelstdlktadksGsTavtvlvs...........
nkdentqtddgakdekkdreteatekeekgdseegqekesngsevhleeLGVLHIANAGNTQAVLCRAGKAYHLTRDHTPGNPQERTRVEKAGSSVHagg
| |||.| . ||||| ||| ||.|| | .|.|..|.|.|| ||
.................................................ekhliianlGDsRavlcrngkaaflteDHkpsrpkEkkRieqAGGsvv...
pNGRVNGILDTTRGLGNYGDPH------LKKAVIPEPYTTSVKIDQHAQFIVMASCGLWDVLTDDDVLSLVKQTLAIHQSRT
..|||| | .| || | . .. |..||..||...... .|.|.|. |.||||.|..|..||...| ... .
.vsRvnGaLAvsRalGDyeykeeeekkaeeqlvsaepevtsierseeddflvlacDGiwDvlsdeevvelvrkrlevadele
|
|||||||||
PP2C | Protein phosphatase 2C | 412-538 | 3.8e-38 | 124.5 | Pfam-A | 113-237 (255) | alignment | ||
Range on Protein: 412-538
Range on HMM: 113-237/255.0
GvLHIANAGNTQAVLCRAGKAY-HLTRDHTPGNPQERTRVEKAGSSVHAggpNGRVNGILDTTRGLGNYgdpHLKK----AVIPEPYTTSVKIDQHAQFI
|..||.| ..|||||...|. ||.||.| ...|| |.|.|| ||. |||||| |. .| || . .||. .|..||..||||.... .|.
k.lyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIeeaggsvsn...ngrvngsLavsRalGdf...elkpkeeqlvsaePdvtsvklteedefl
VMASCGLWDVLTDDDVLSLVKQTLAIHQSRTQ
..|| ||||||.|... .||...| ..| ..
iLasdGlwdvlsdqeavdlvrselskkkspme
|
|||||||||
PP2C | Protein phosphatase 2C | 412-538 | 3.8e-38 | 124.5 | In-house | 113-237 (255) | alignment | ||
Range on Protein: 412-538
Range on HMM: 113-237/255.0
GvLHIANAGNTQAVLCRAGKAY-HLTRDHTPGNPQERTRVEKAGSSVHAggpNGRVNGILDTTRGLGNYgdpHLKK----AVIPEPYTTSVKIDQHAQFI
|..||.| ..|||||...|. ||.||.| ...|| |.|.|| ||. |||||| |. .| || . .||. .|..||..||||.... .|.
k.lyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIeeaggsvsn...ngrvngsLavsRalGdf...elkpkeeqlvsaePdvtsvklteedefl
VMASCGLWDVLTDDDVLSLVKQTLAIHQSRTQ
..|| ||||||.|... .||...| ..| ..
iLasdGlwdvlsdqeavdlvrselskkkspme
|
|||||||||
PPM_PTC7 | 414-533 | 2.3e-35 | 115.3 | In-house | 115-237 (259) | alignment | |||
Range on Protein: 414-533
Range on HMM: 115-237/259.0
LHIANAGNTQAVLCRAGKAY-HLTRDHTPGNPQERTRVEKAGSSVHAGgPNGRVNGILDTTRGLGNYgdpHLK------KAVIPEPYTTSVKIDQHAQFI
|..||.|...||||| |.|. ||.||.| |..|| |.|.|| ||. |||||| |. .| .| . .|| ..|..||...|.||| . .|.
lyvAnvGDSravLcrsgnavkqltedHkpsnedEreRiegaggsvsnv.gngrvngvlavsRafGdf...elkpketeeqlvsaePdisstkideedefl
VMASCGLWDVLTDDDVLSLVKQTLAIH
..|| |||||..|... .||...|. .
iLasdGlwdvvsdqeavdlvrselskk
|
|||||||||
0049733 | PP2C-like | 170-538 | 2.2e-28 | 92.3 | In-house | 13-209 (235) | alignment | ||
Range on Protein: 170-538
Range on HMM: 13-209/235.0
RWKSKMEDTRVFqdyygndvNKCFFGIYDGYNGRFAADIAANDLHHVFLSELQKvdeR---Vsctcavnladnndltdyelergspivrsdsirhilhee
|... .||. .. . .|...|| .| |...|.. |....|..|..
rvrkvneDavlv........glllfavaDGhgghaagevasellvetllellle...lllld......................................
siniiqqimhtcesnlmkmsdivsqesvgdwptrkkknrdpefekVSQAYHMSYLYLDRYLSYGINETSLVRWSGCSALSLLINSKEqleaenpgnkden
. .| . ..|.....| . ....|..|. .|. ..
.............................................leealrkaflaaneallelalaspelagmgtTavvalldggk.............
tqtddgakdekkdreteatekeekgdseegqekesngsevhleelgvLHIANAGNTQAVLCRAGKAYHLTRDHTPGNPQERTRVEKAGSSVhaggpngRV
|..||.|.. |.|.| ||...||.||.| |..|| |...|| | ||
...............................................lyvanvGDsrayllrdgklvqltedhspvnelerqriitaggav.......rv
NGILDTTRGLGnygDPHLKkavipePYTTSVKIDQHAqFIVMASCGLWDVLTDDDVLSLVKQtlaiHQSRTQ
.|.| || || |..|| |..|....... |...|| ||||||.|.....|... . .
pgrlaltralG...dlllk......pdvtvlelepgd.flllasDGlwdvlsdeeivdllrs....ldleea
|
|||||||||
subfamily_PPM1E_pd | Subfamily PPM1E | 413-534 | 2.5e-26 | 85.5 | In-house | 115-232 (265) | alignment | ||
Range on Protein: 413-534
Range on HMM: 115-232/265.0
VLHIANAGNTQAVLCRAGKAYHLTRDHTPGNPQERTRVEKAGSSVHAGGpNGRVNGILDTTRGLgnyGDPHLKKAVIPEPYTTSVKIDQHAQFIVMASCG
|..| |. ||.|.| |.| .|.. | | ...|. |.|.|| | | . ||||.| .| . ||..||. |. |. ...|..|.. .....|. |
qlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvig.awRvnGvLsvsRai...GDvklkpyvsgeadvaeveldgseeylilacDG
LWDVLTDDDVLSLVKQTLAIHQ
||||.....|..||.. || ..
lwDvvneeevvklveefladga
|
|||||||||
subfamily_PPM1G_pd | Subfamily PPM1G | 357-534 | 1.2e-24 | 80.2 | In-house | 249-433 (473) | alignment | ||
Range on Protein: 357-534
Range on HMM: 249-433/473.0
AENPGNKDENTQTDDGAKDEKKDRETEATEKEEKGDSEEGQEKESN----GSEVHLEELGVLHIANAGNTQAVLCRAGKAYHLTRDHTPGNPQERTRVEK
|. ...|. . | ...|......| .|..|. |..|..|.. . | | . | .||||.. .||.|.||| | || | ...|..|.||
eedeeeaeeeeeeedeedeeeeeedgegeeakeeldgseekeepGedsGttAvvaLlkekklivAnaGDsRcvlsrnGkAldlslDHkPeDevEleRiek
AGSSVHAggpNGRVNGILDTTRGLGNYGD------PHLKKAVIPEPYTTSVKIDQHAQFIVMASCGLWDVLTDDDVLSLVKQTLAIHQ
|| |. .||||| |. | ||.. |. . . | .. .. .|.|.|. |.|.|.. ..|. |.. |. ..
AGGkvde...dgRvnGGLnlsRAlGDhaYkkneeLplkeqmisAlPDikvltlteedeFlvlAcDGiWnvmesqevvdfvraklkkge
|
|||||||||
subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 415-528 | 1.2e-23 | 76.7 | In-house | 110-222 (255) | alignment | ||
Range on Protein: 415-528
Range on HMM: 110-222/255.0
HIANAGNTQAVLC-RAGKAYHLTRDHTPGNPQERTRVEKAGSSVHAGGPNGRVNGILDTTRGLGnygDPHLKKAVIPEPYTT-SVKIDQHAQFIVMASCG
||| |....||| . | | |. || | ...|. |....| | .. |||| | .| || | .|. |.|.|. . |..| .. .|...| |
yianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralG...dsflePfvvpdPdlsqsleiskkdkflilacdG
LWDVLTDDDVLSLVKQ
.||...|.. ..| .
iwdlisdeeaveivag
|
|||||||||
subfamily_ILKAP_pd | Subfamily ILKAP | 413-542 | 4e-22 | 71.7 | In-house | 126-255 (293) | alignment | ||
Range on Protein: 413-542
Range on HMM: 126-255/293.0
VLHIANAGNTQAVLCRAGKAYH------LTRDHTPGNPQERTRVEKAGSSVHaggpNGRVNGILDTTRGLGnygDPHL-KKAVIPEPYTTSVKIDQHAQF
||..|| |...|||.| .. . ||.|||| . .|| |..|||..|. .|||.|.|. .| .| | . . || | .. ..... .|
vlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaGgvvr....dgrvlGvlevsrsiG...dgrfkrlGvistPdvkkceLtendlf
IVMASCGLWDVLTDDDVLSLVKQTLAIHQSRTQAENV
.|.| |||.|.. |.|.. . ..| ... .. ..
vvlaCdGLwkvfsadevvkfilkvledeeddrkikee
|
|||||||||
subfamily_PPM1K_pd | Subfamily PPM1K | 412-530 | 7.6e-22 | 70.7 | In-house | 111-229 (263) | alignment | ||
Range on Protein: 412-530
Range on HMM: 111-229/263.0
GVLHIANAGNTQAVLCRAGKAYHLTRDHTPGNPQERTRVEKAGSSVHAGG-PNGRVNGILDTTRGLGnygDPHLKK-AVIPEPYTTSVKIDQ-HAQFIVM
| .|. |...|.||| ||| .|||||.| .|. |. .|| ||. . .||| | || || | ||. || .| | |.|.| . |.|.
telvlaslGdsrailcrnGkakkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtrslG...dldlkryGviatPetkslkvdhaadsflvl
ASCGLWDVLTDDDVLSLVKQTL
. |. .|... .. ||..
itdgisfvvnsqelcdlvrlch
|
|||||||||
subfamily_PPM1G2_pd | Subfamily PPM1G2 | 408-533 | 1e-20 | 66.8 | In-house | 124-250 (287) | alignment | ||
Range on Protein: 408-533
Range on HMM: 124-250/287.0
LEELGvLHIANAGNTQAVLCRAGKAYHLTRDHTPGNPQERTRVEKAGSSVHAggpnGRVNGILDTTRGLGNYGDPH------LKKAVIPEPYTTSVKIDQ
..| | .||||. .|||. .|.. |..|| | . .|..|...|| |. .|||| | | ||.. . . | .| . |.|.
ikeek.lyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfvel....nrvngnLalsralgDfefkknvkkkpeeqivtavPDvlvkklde
HAQFIVMASCGLWDVLTDDDVLSLVKQTLAIH
. |.|.| |.|||||...|. ||.. |. .
ddeflvLaCDGiWDvltnkevvdlvrerlvsg
|
|||||||||
subfamily_PPM1L_pd | Subfamily PPM1L | 414-530 | 3.2e-20 | 65.5 | In-house | 120-236 (269) | alignment | ||
Range on Protein: 414-530
Range on HMM: 120-236/269.0
LHIANAGNTQAVLC-RAGKAYHLTRDHTPGNPQERTRVEKAGSSVHAGGpNGRVNGILDTTRGLGNYGDPHlKKAVIPEPYTTSVKIDQH-AQFIVMASC
| .|| |... ||. . ||| |. || | ...|| |..||| . | ||.|.| |.| ||.| . |. ||..| . ..|.| .|...||
livanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrG.vwrvaGvlatsralGdyplkd.knlviadpdiltfdlddhkpeflilasd
GLWDVLTDDDVLSLVKQTL
|||| ..... . .|. |
Glwdtfsneeavrfikerl
|
|||||||||
subfamily_Dicty-PPM-1_pd | Subfamily Dicty-PPM-1 | 402-531 | 2e-17 | 56.0 | In-house | 116-243 (276) | alignment | ||
Range on Protein: 402-531
Range on HMM: 116-243/276.0
NGSEVHLEELGVLHIANAGNTQAVLCRAGKAYHLTRDHTPGNPQERTRVEKAGSSVHAGgpNGRVNGILdTTRGLGNYGDPHLKKAVIPEPYTT-SVKID
.| | . .. | .|| |.. | |.| .. .|. || .|.|. |. . | .. . . |.||.. .| ||.. .| .| ||| . . .
dGeeqqqqqqrylqvanvGdssaflsrGneslelskdhkatdpeekqrikddGitlsdn..qtrinGla.vsralGdhfikelniGlisepyvsnrillt
QHAQFIVMASCGLWDVLTDDDVLSLVKQTLA
. .|...|| |||||.. .| . ||
pfdkflivasdGlwdvisGkdaiekvkslyd
|
|||||||||
subfamily_KAPP-like_pd | Subfamily KAPP-like | 414-531 | 1.4e-16 | 53.3 | In-house | 118-233 (266) | alignment | ||
Range on Protein: 414-531
Range on HMM: 118-233/266.0
LHIANAGNTQAVLCRAGKAYHLTRDHTPGNPQERTRVEKAGSSVHAGgpNGRVNGILdTTRGLGNYGDPHLKKAVIPEPYTT-SVKIDQHAQFIVMASCG
| .|| |.. | |.| .. .|. || .|.|. |. . | .. . . |.||.. .| ||.. .| .| ||| . . . . .|...|| |
lqvanvGdssaflsrGneslelskdhkakdpeekqrikddGitlsdn..qtrinGla.vsralGdhfikelniGlisepyvsnrilltpfdkflivasdG
LWDVLTDDDVLSLVKQTLA
||||.. .| . ||
lwdvisGkdaiekvkslyd
|
|||||||||
subfamily_PHLPP_pd | Subfamily PHLPP | 413-528 | 1.3e-13 | 43.4 | In-house | 106-214 (246) | alignment | ||
Range on Protein: 413-528
Range on HMM: 106-214/246.0
VLHIANAGNTQAVLCRAGKAYHLTRDHTPGNPqERTRVEKAGSSVHAggpNGRVNGILDTTRGLGNYgdpHLKKAVIPEPYTTSVKIDQHAQFIVMASCG
.|..|. |. ||||.| || |.. .. . | |. .| . . ....||.. .|| || . .| |.|.| .|.. . .... .
sLevAsvGtlqavliRngkklrlsksyviekd.elkrikeakaiite...dnkingviestrllGyt...flfPvvlPkphvrevlLteqdellivGnka
LWDVLTDDDVLSLVKQ
||.|| |.. . |..
lWevlsideaveavrk
|
|||||||||
PPM_PTC7_SpoIIE | 412-533 | 3.1e-13 | 43.1 | In-house | 105-212 (230) | alignment | |||
Range on Protein: 412-533
Range on HMM: 105-212/230.0
GVLHIANAGNTQAVLCRA-GKayhltrdhtpgnpqERTRVeKAGSSVHAGGPNGRVNGILDTTRGLGNYGDPHLKKAVIPEPYtTSVKID-QHAQFIVMA
| |..||||. ..|.|. |. ||.|. .|| .. | .|||.| | .. | . . . | .||. || ... .. .|...|
gklyvanaGdsppllvrddgg..............ereri.vagglpslGilpgrvfgvlavslapGdllllytDGvveaepd.tsdgelfgkdeflila
SCGLWDVLTDDDVLSLVKQTLAIH
| ||||||.......||...| .
sdglwdvlspqelvdlvrdelekp
|
|||||||||
subfamily_PDP_pd | Subfamily PDP | 408-539 | 3.1e-11 | 36.0 | In-house | 161-321 (398) | alignment | ||
Range on Protein: 408-539
Range on HMM: 161-321/398.0
LEELGvLHIANAGNTQAVLCRAG-----KAYHLTRDHTPGNPQERTRVEKAGSSVHA--GGPNGRVNGILDTTRGLGNYG---DP-----HLKK----AV
.|. ||.||.| ..|||.. .| .|..|.| |..| .|..|. . . |||. | | .| |.. . .|.| ..
iegte.lhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwseelqkkvlekaylkvl
IP-----------EPYTTSVKIDQHAQFIVMASCGLWDVLTDDDVLSLVKQTLAIHQSRTQA
| || || |. .. .|.|.|. ||||.|....| |||.. || ......
epkdyktPPYltaePevtshklrendkFLvlatDGLwdllsneevvslVgehlakkkekepv
|
|||||||||
subfamily_PPM1D_pd | Subfamily PPM1D | 487-537 | 7.4e-09 | 28.1 | In-house | 221-272 (309) | alignment | ||
Range on Protein: 487-537
Range on HMM: 221-272/309.0
AVIPEPYTTSVKIDQHAQ-FIVMASCGLWDVLTDDDVLSLVKQTLAIHQSRT
| |||... ...|.. . ||..|| |||.||| .|. |.|... ....
vvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelke
|
|||||||||
subfamily_Dicty-PPM1L-like_pd | Subfamily Dicty-PPM1L-like | 445-545 | 2e-08 | 26.4 | In-house | 181-278 (305) | alignment | ||
Range on Protein: 445-545
Range on HMM: 181-278/305.0
QERTRVEKAGSSVHAGGpNGRVNGILDTTRglgNYGDPHLKKAVIPEPYTTSVKIDQH-AQFIVMASCGLWDVLTDDDVLSLVKQTLAIHQSRTQAENVP
..| |.| ..... | . .||..| | . || ||. |||.. . . ||.|.| |||.|| .|| ||. | ...| . | .
eiririeslqaalynyg.ellvnrllkksr...skGdknlkelviPnndspllvvakanDqflvlatdGlwevlsyqdvveevkellrdkssqkkiewdf
DE
.|
ne
|
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subfamily_Choan-PPM1K-like_pd | Subfamily Choan-PPM1K-like | 413-492 | 4.6e-08 | 25.9 | In-house | 99-194 (292) | alignment | ||
Range on Protein: 413-492
Range on HMM: 99-194/292.0
VLHIANAGNTQAVLCR--AGKAY---HLTRDHTPGNPQERTRVEKAGSSVHA-----GGP--NGRV------NGILDTTRGLGNYgdpHLKKA-VIPEP
| .|| |...|.| | .| | |.||| | .|.|| |. .|| |. | || .| | .| ||.. ||..| |. ||
alilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraGGrveptrvrgwgfrGtarvwrrrqqeGdlalsralGdf...hlfeaGvvaeP
|
|||||||||
subfamily_PPM1H_pd | Subfamily PPM1H | 158-293 | 4.9e-08 | 25.1 | In-house | 33-155 (404) | alignment | ||
Range on Protein: 158-293
Range on HMM: 33-155/404.0
VRAVGICSDDNSRWKSKMEdtrvFQDYYGNDVNKCFFGIYDGYNGRFAADIAANDLHHVFLSELQKVDERVSCTCAvnladnndL---TDY--Elergsp
.. . .............. .. . .. .||..||. | || .|.. ||.. ..|..| | . .. | . .
akvlllkkekkeksvtskp....kekseeeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellleksa........eeeenteess......
IVRSDSIRHILHEESINIIQQIMHTCESNLMKMSDIVSQES
. | ..| .|..|. . .. || ..| . ...|
kespssvseiyeekeiskeeLviGalesaflemDeqiarer
|
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subfamily_PPM1L_pd | Subfamily PPM1L | 172-235 | 2.6e-07 | 23.2 | In-house | 16-79 (269) | alignment | ||
Range on Protein: 172-235
Range on HMM: 16-79/269.0
KSKMEDTRVFQDYYGNDVNKCFFGIYDGYNGRFAADIAANDLHHVFLSELQKVDERVSCTCAVN
. .||| ... |.... ||...||. | |||. | . | . ...|...|. | .|
rprmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentepin
|
|||||||||
subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 172-222 | 6e-07 | 22.0 | In-house | 17-67 (255) | alignment | ||
Range on Protein: 172-222
Range on HMM: 17-67/255.0
KSKMEDTRVFQDYYGNDVNKCFFGIYDGYNGRFAADIAANDLHHVFLSELQ
.. ||| | . .. .. .. ..||. || ||..|...|.... . |.
rptmedelviyGsfrdksdedyyalfdGhgGraaakfaseelykilaelld
|
|||||||||
subfamily_TAB1_pd | Subfamily TAB1 | 414-517 | 8.1e-07 | 21.1 | In-house | 143-260 (333) | alignment | ||
Range on Protein: 414-517
Range on HMM: 143-260/333.0
LHIANAGNTQAVLCR---AGKAYHLTRDHTPGNPQERTRVEKAGSSVHAGGPNGRVnGILDTTRGLGNYGDPHL-------KK----AVIPEPYTTSV-K
|..||.|. .|.|.. | | ||| |..| .|... | .. |.|. | ..|| .|.| .. .. || || . .
LyVaNvGdsrAllvkrkesekvkqLsvdHttdNedEllRlkdLGldieqikrnkrl.gskentRsiGdykvkkgykdvdilssakgePviaePdiqgayp
IDQHAQFIVMASCGLWDVL
||. .|.|. | |. |
iddityflvlmSdGvyktL
|
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subfamily_PPM1H_pd | Subfamily PPM1H | 462-536 | 9.1e-07 | 20.9 | In-house | 273-357 (404) | alignment | ||
Range on Protein: 462-536
Range on HMM: 273-357/404.0
PNGRVNGILDTTRGLGNYG------DPHLKKAVIPEPYTTSVKIDQH----AQFIVMASCGLWDVLTDDDVLSLVKQTLAIHQSR
|. . . .|||||.. . ..| . |.| . . ..| . ...|. ||||||....|. .|...|. ...
kkaRllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvepe
|
|||||||||
PPM_PTC7_motif | 507-531 | 1.7e-06 | 21.5 | In-house | 1-25 (51) | alignment | |||
Range on Protein: 507-531
Range on HMM: 1-25/51.0
VMASCGLWDVLTDDDVLSLVKQTLA
..|| ||||||.|... .||...|.
iLAsDGLWDvlsdqeavdlvrdqls
|
|||||||||
subfamily_PPM1H_pd | Subfamily PPM1H | 411-451 | 3.1e-06 | 19.2 | In-house | 173-211 (404) | alignment | ||
Range on Protein: 411-451
Range on HMM: 173-211/404.0
LGVLHIANAGNTQAVLCRAGKAYHLTRDHTPGNpqERTRVE
|| |..||||...|.|.| .. | .|.|| || |.
lgklYvanaGDsRailvrkdeiiplsadftPet..eRqRlq
|
|||||||||
subfamily_PPM1E_pd | Subfamily PPM1E | 173-228 | 6.9e-06 | 18.4 | In-house | 16-77 (265) | alignment | ||
Range on Protein: 173-228
Range on HMM: 16-77/265.0
SKMEDTRV----FQDYYG--NDVNKCFFGIYDGYNGRFAADIAANDLHHVFLSELQKVDERV
|||| | . ... .. .. ||...||. | ||. ||. ||.. .. . .. .
rkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa
|