Gene PPM1K-1 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PPM1K
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP190_AA protein Get Run
SpurP190_AA_94-289 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPM1K_pd Subfamily PPM1K 97-290 1.1e-112 368.5 In-house 5-197 (263) alignment 
Range on Protein: 97-290
Range on HMM: 5-197/263.0
RIGKDSLIGRRAENEDRICIKELHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHDLQIVLKNAFEDLNNKLTRYLYFHYPETEYENSGSTATV
 .|||||||.||||||||..|||.|.||||..|||||||.|.|.||..||..||..||.|.||.||||||||.|..||.|||.|...|.|...||.||||
svGkdsliGkraenedriklkeldpellyvavfdGhaGsaaadfvhdklekilkrllekekdleivlknafeeldkklkrylefsvaeaellssGttatv

SLLRNGNELVLANLGDSRAILCRNGKAKRLTNDHDPEYNTtEKERIKAAGGSFTWNSLGKPLVNSVLTMTRSFGDVTLKRYGVIATPETRSLEV
||||.|.|||||.|||||||||||||||.||.|||||... |||||||||||..||||||||||..|.||||.||..||||||||||||.||.|
sllrdGtelvlaslGdsrailcrnGkakkltrdhdPelee.ekerikaagGsvewnslgkplvngrlamtrslGdldlkryGviatPetkslkv
0034914 PP2C-like 95-289 4.3e-44 143.6 In-house 20-224 (295) alignment 
Range on Protein: 95-289
Range on HMM: 20-224/295.0
VGRIGKDSLIGRRAENEDRICIKE----LHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLER--------EHDLQIVLKNAFEDLNNKLTRYLYFhy
. |.|  | .||| .|||....      |...||..|.|||| |. | ......|  .|. .||.        ..|.. .|..||  ....| ....   
llrvgvasdqGrrksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelall..

pETEYENSGSTATVSLLrNGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWnslgkPLVNSVLTMTRSFGDVTLK-------
 . |. .||.||.| |.  || |..||.|||||.|.|||....||.||.|  | .|.|||..|||  ..     . || || .||..||. ||       
.rpelagsGtTavvali.rgnklyvanvGDSravllrngelvqltvdhkpv.nelererilsaggavsh.....grvngvlavtRalGdfdlklllslll

-RYGVIATPETRSLE
 ...|.|.|....||
leplvsaePdvtvle
PP2Cc_SM00332 99-287 6.4e-40 130.2 In-house 13-206 (274) alignment 
Range on Protein: 99-287
Range on HMM: 13-206/274.0
GKDSLIGRRAENEDRICIKEL---HPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD-----LQIVLKNAFEDLNNKLTRYLYFHYPETeyENS
||.|  |.| ..||.....     . . |..|.||||.|| ....|  .|  .||  |. . |      . .||.||........     . .|   ..|
gkssmqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen..als

GSTATVSLLRNGNeLVLANLGDSRAILCRNGKAKRLTNDHDPeYNTTEKERIKAAGGSFTWNslgkpLVNSVLTMTRSFGDVTLKR------YGVIATPE
||||.|.||.... |..||.|||||.|||||||..|..|| |  . .|..|||.|||.  ..      || .| ..|.|||. ||.       ...|.|.
Gstavvallkked.lyvanvGDSravlcrngkavqlsvdhkp.edederkRikkaggvvekg.....rvngglavsrafGdhflkknkklkepyitaepd

TRS
.  
vkv
PP2C Protein phosphatase 2C 102-288 3.9e-38 124.5 Pfam-A 7-196 (255) alignment 
Range on Protein: 102-288
Range on HMM: 7-196/255.0
SLIGRRAENEDRICIKE------LHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD--LQIVLKNAFED-LNNKLTRylyfHYPETEYENSGS
.| |.| ..||.... .         .  ....||||.|..| .| . .|| .||   . . .  .. .|...|.  ....|..    .   || ..|||
elqgarksmedahialknlekssgkssvaffavfdghggreaakyarehleeilkeqksflelekvekalrksfladtdeelks....skantepsksGs

TATVSLLRNGNeLVLANLGDSRAILCRNGKAK-RLTNDHDPEyNTTEKERIKAAGGSFTWnslgKPLVNSVLTMTRSFGDVTLKR---YGVIATPETRSL
||.|.|.|. . | .||.|||||.|||...|| .||.||.|. .. |.|||..||||. .    .  || .| ..|..||. ||.   . |.| |...| 
tavvalirgkk.lyvAnvGDSravLcrkdnakkeltedHkps.dedEreRIeeaggsvsn....ngrvngsLavsRalGdfelkpkeeqlvsaePdvtsv
PP2C Protein phosphatase 2C 102-288 3.9e-38 124.5 In-house 7-196 (255) alignment 
Range on Protein: 102-288
Range on HMM: 7-196/255.0
SLIGRRAENEDRICIKE------LHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD--LQIVLKNAFED-LNNKLTRylyfHYPETEYENSGS
.| |.| ..||.... .         .  ....||||.|..| .| . .|| .||   . . .  .. .|...|.  ....|..    .   || ..|||
elqgarksmedahialknlekssgkssvaffavfdghggreaakyarehleeilkeqksflelekvekalrksfladtdeelks....skantepsksGs

TATVSLLRNGNeLVLANLGDSRAILCRNGKAK-RLTNDHDPEyNTTEKERIKAAGGSFTWnslgKPLVNSVLTMTRSFGDVTLKR---YGVIATPETRSL
||.|.|.|. . | .||.|||||.|||...|| .||.||.|. .. |.|||..||||. .    .  || .| ..|..||. ||.   . |.| |...| 
tavvalirgkk.lyvAnvGDSravLcrkdnakkeltedHkps.dedEreRIeeaggsvsn....ngrvngsLavsRalGdfelkpkeeqlvsaePdvtsv
PPM_PTC7 105-287 9.2e-38 123.1 In-house 10-200 (259) alignment 
Range on Protein: 105-287
Range on HMM: 10-200/259.0
GRRAENEDRICIKE------LHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD--LQIVLKNAFED--LNNKLTRylyfHYPETEYENSGSTA
|.| ..||. ...          .  ....||||.|..| .|.. .|| .||   . | .  |. .|...|.   ....|..    .   || ..|||||
gfrksmedahialanlesssgkdsvaffavfdghggreaakyarehleeilkerksfeeleklekalrksflaldtdeelks....seantepstsGstA

TVSLLRNGNeLVLANLGDSRAILCRNGKAK-RLTNDHDPEyNTTEKERIKAAGGSFTWNslGKPLVNSVLTMTRSFGDVTLKR-----YGVIATPETRS
.| |... . |  ||.|||||.|||.|.|. .||.||.|. |. |.|||..||||. .   |.  || || ..|.|||. ||.       |.|.|.. |
vvalitgsk.lyvAnvGDSravLcrsgnavkqltedHkps.nedEreRiegaggsvsnv..gngrvngvlavsRafGdfelkpketeeqlvsaePdiss
subfamily_PPM1A_pd Subfamily PPM1A 97-277 1.2e-33 109.7 In-house 13-195 (282) alignment 
Range on Protein: 97-277
Range on HMM: 13-195/282.0
RIGKDSLIGRRAENEDRICIKELHPNL---LYVGIFDGHAGSMAVDYVHHNLEFHLKF---------WLEREHDLQIVLKNAFEDLNNKLTRYlyFHYPE
|.| .|  |.|.|.||. ..    ..|    .  .||||||| ...||...|  ..             . ..... .|...| .|.... .   ..  .
rygvssmqgwrvemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenileeeelkeaaleasekdevkealrqgfLaldeairel..stdlk

TEyENSGSTATVSLLRnGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTwnslgKPLVNSVLTMTRSFGDVTLKRY
|. ..|||||.. |..  ..|..||||||||.|||||||..||.|| |. ...||.||..|||| .     .  ||  | ..|..|| ..|. 
ta.dksGsTavtvlvs.ekhliianlGDsRavlcrngkaaflteDHkps.rpkEkkRieqAGGsvv.....vsRvnGaLAvsRalGDyeykee
0049733 PP2C-like 99-285 2.6e-31 101.9 In-house 6-170 (235) alignment 
Range on Protein: 99-285
Range on HMM: 6-170/235.0
GKDSLIGR-RAENEDRICIkelhpNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLERE--HDLQIVLKNAFEDLNNKLTRYLYFHYpetEYENSGSTAT
|  | ||| | .|||....     .||.....||| |. | ... ..|  .|. .|..   .||. .|..||. .|. | .. . ..   |.  .|.||.
gaasdigrvrkvneDavlv.....glllfavaDGhgghaagevasellvetllelllelllldleealrkaflaaneallelalasp...elagmgtTav

VSLLRnGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFtwnslgkpLVNSVLTMTRSFGDVTLKrygviatPET
| ||. |. |..||.|||||.|.|.||. .|| || |  | .|..||..||| .         |. .| .||..|| .||       |..
valld.ggklyvanvGDsrayllrdgklvqltedhspv.nelerqriitaggav........rvpgrlaltralGdlllk.......pdv
subfamily_PPM1G2_pd Subfamily PPM1G2 99-278 3.8e-29 94.5 In-house 22-196 (287) alignment 
Range on Protein: 99-278
Range on HMM: 22-196/287.0
GKDSLIGRRAENEDRICI------KELHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLE-REHDLQIVLKNAFEDLNNKLTRYlyfhyPETEYENSG
|  .. | | . ||   .      |. ...| ....|||| |. .  |. ..|   ..   . .|  |. .||.|| .....|..       ... |..|
gssamqGyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkd.....eklkdesaG

STATVSLLRNGNeLVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNSlgkplVNSVLTMTRSFGDVTLKRYG
|||.| |... . |. || |||||.|. .|..| |. || |. ...||.||.||||    |      || .| . |..|| . |.  
stavvvlikeek.lyvanaGDsravlsskgnvkalsfDhkPq.eesekkriiaagGfvelnr.....vngnLalsralgDfefkknv
subfamily_PPM1E_pd Subfamily PPM1E 121-288 4.1e-29 94.6 In-house 38-195 (265) alignment 
Range on Protein: 121-288
Range on HMM: 38-195/265.0
PNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHDLQIVLKNAFEDLNNKLTRYlyfhyPETEYENSGSTATVSLLRNgNELVLANLGDSRAILCRN
..  . ..||||.|. | .|  ..|  .|    . ..| .  ||.||. .......       | |  .||||| | |... ..| .| ||||.|.|.|.
keraffavfDGHgGveaakyaaahlhellvrqeklkedpaealkeafkltDerflqk.....aereklksGstavvvliek.dqlyvaWlGDsqallvrk

GKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNslGKPLVNSVLTMTRSFGDVTLKRYgVIATPETRSL
|.| .|.. | || .  ||.||..|||   .   |.  || ||...|. |||.||.| |.. ... ..
geavqlmkpHkPe.redEkkRieeagGlvvvi..gawRvnGvLsvsRaiGDvklkpy.vsgeadvaev
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 97-284 1.9e-28 92.4 In-house 7-186 (255) alignment 
Range on Protein: 97-284
Range on HMM: 7-186/255.0
RIGKDSLIGRRAENEDRICIKEL---HPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD-LQIVLKNAFEDLNNKLtrylyfhypeTEY-ENSG
..|.  .||||.  ||.. |      ...  |. .||||.|. | ..  ..|.  |.  |. ..   . .||.|..... ..          .|.    |
kvgfsdmiGrrptmedelviyGsfrdksdedyyalfdGhgGraaakfaseelykilaelldlnnanPvkslkkaykeistqi..........serpkfiG

STATvSLLRNGNELVLANLGDSRAILC-RNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNsLGKPLVNSVLTMTRSFGDVTLKRYgVIATPE
.||. |.|  ..  ..||.||||..|| ..| ||||. || |  .  |..||...||    .      ||  |...|..||. |. . |.. |.
ttaa.svliiedkvyianvGdsrvvlcqkdgtakrlsldhkPs.eeseekriselGGtvvst.vvtsrvnGtlavsralGdsflePf.vvpdPd
subfamily_PPM1L_pd Subfamily PPM1L 102-288 3.9e-25 81.6 In-house 11-202 (269) alignment 
Range on Protein: 102-288
Range on HMM: 11-202/269.0
SLIGRRAENEDRICIKELHPN---LLYVGIFDGHAGSMAVDYVHHNLEFHLKFWL-----EREHDLQIVLKNAFEDLNNKLTrYLYFHYPETEYENSGST
|. ||| . |||. |.|   |     ....|||| | .| ..... |   .|  |     ..|. . |  .. ..|    .  .   .  ..... .|.|
svlGrrprmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentepinfsklltdeilsvd.ekllekakraediaGtt

ATVSLLRnGNELVLANLGDSRAILC-RNGKAKRLTNDHDPeYNTTEKERIKAAGGSFTWNslGKPLVNSVLTMTRSFGDVTLKRYG-VIATPETRSL
| ..|.. ...|..||.|||| .|. ..|||  |. || | ..  |. ||| |||  ...  |   |. ||...|..||  ||    |||.|.  ..
alialvq.esdlivanvGdsrGvlydkrGkaiplsfdhkp.qqvkerkrikkaGGfiafr..GvwrvaGvlatsralGdyplkdknlviadpdiltf
subfamily_ILKAP_pd Subfamily ILKAP 123-288 1.1e-23 76.8 In-house 43-210 (293) alignment 
Range on Protein: 123-288
Range on HMM: 43-210/293.0
LLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEReHDLQI---VLKNAFED-LNNKLTRYLYFHYPETEYENSGSTATVSLLRNgNELVLANLGDSRAILC
. | ..||||||| | ... ..|. ...  | . .|..     .|... |  ...   .|     ..     |||||| |  . | |  ||||||.|.|.
vsyyavfdGhaGsrasefaaeklhkkileklpk.sdvsakekeikkclvdsfkktdeefLklaskakPvWkdGstatvvlvld.nvlyvanlGdskavlv

RNGKAKR------LTNDHDPEyNTTEKERIKAAGGSFTWNSlgkplVNSVLTMTRSFGDVTLKRYGVIATPETRSL
|. .. .      || ||.|  .  |..||. |||. . .      |. || ..|| ||   || |||.||... .
rkkeegdkiasvvLtkdhtpv.kyeerkriqkaGgvvrdgr.....vlGvlevsrsiGdgrfkrlGvistPdvkkc
subfamily_PPM1G_pd Subfamily PPM1G 184-276 1.2e-22 73.6 In-house 290-376 (473) alignment 
Range on Protein: 184-276
Range on HMM: 290-376/473.0
ETEYENSGSTATVSLLRnGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNSlgKplVNSVLTMTRSFGDVTLKR
|.. |.||.||.| ||. ...|. || ||||..|.|||||  |  || || . .|.|||..|||  . .   .  ||  | . | .|| . |.
eepGedsGttAvvaLlk.ekklivAnaGDsRcvlsrnGkAldlslDHkPe.DevEleRiekAGGkvdedg..R..vnGGLnlsRAlGDhaYkk
subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 106-285 1.3e-22 73.7 In-house 3-196 (292) alignment 
Range on Protein: 106-285
Range on HMM: 3-196/292.0
RRAENEDRICIKELHPNLLY-VGIFDGHA--GSMAVDYVHHNLEFHLKFWLEREHDLQIVLKNAFEDLNNKLTRYlYFhypeTEYENSGSTATVSLLRNG
 . ||.|| .. |    | .   ..|||   |    ..   .|| .|     .  .|   | .   |.  || .  .      . |....... .  |..
nkkenqdrfllvegsealtflaavldGhGvnGdkvaqlaedtlevelleltrqlqelsealllrildiaakldkl.ti....daresattavvcarvrdd

NELVLANLGDSRAILCR-----NGKAKRLTNDHDPEyNTTEKERIKAAGGSFT------WNSLGKPLV------NSVLTMTRSFGDVTLKRYGVIATPET
 .|.|||.|||||.| |     . . . |..|| || .  |..||..|||  .      |   | . |      .  |...|. ||. |.  ||.| || 
ralilanvGdsrallgrclggsdyeliPlsrdhkPe.dPderarilraGGrveptrvrgwgfrGtarvwrrrqqeGdlalsralGdfhlfeaGvvaePel
PPM_PTC7_SpoIIE 105-276 5.3e-20 65.2 In-house 10-162 (230) alignment 
Range on Protein: 105-276
Range on HMM: 10-162/230.0
GRRAENEDRICIKE------LHPNLLYVGIFDGHAGSMavDYVHHNLEFHLKFWLEREHD-LQIVLKNAFEDLNNKLTRYlyfhypeteYENSGSTATVS
|.| ..||. ...        .   |.||..||| |..   ...  |   |.    .... .  .|..... |. .|. .          ..||.||.| 
garksmedahispansekssggrlalvvgdvdGhGgra..alamgllrtalrelafaglekpeeilrrlnlalaadlede.........psssgaTavva

LLRNGN-ELVLANLGDSRAILCRN-GKakrltndhdpeynttEKERIkAAGGSFTwNSLGKPLVNSVLTMTRSFGDVTLKR
|... . .| .||.|||...|.|. |.               |.||| .|||     ...   |. ||......||. |. 
lidpstgklyvanaGdsppllvrddgg...............ereri.vagglps.lGilpgrvfgvlavslapGdlllly
subfamily_PPM1D_pd Subfamily PPM1D 105-250 1.9e-19 62.9 In-house 11-172 (309) alignment 
Range on Protein: 105-250
Range on HMM: 11-172/309.0
GRRAENEDRICIKELH------PNLLYVGIFDGHAGSMAVDYVHHNLEFHL----KFWLEREHDLQIVLKNAFEDLNNKLTRYlYFHYPETE---YENSG
| |   ||...|.  .       .  .|..|||| |  |  .....|   .    ||. . ..|..  ...|| ...... .  . ..|.|.   .  .|
GgrkymeDvvaivleeeesaeelevafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkk.leeWpktksgllstaG

STATVSLLRNgNELVLANLGDSRAILCRNGK------AKRLTNDHDPEYnTTEKERIKAAGGSFT
.||.| ..|. ..| .|. |||...|  . .      || ||.|| ||   .|||||. .||. .
ttasvviirr.eklyvahvGDsaivlgvkepkekklrakeltkdHkPes.peekerieelGGeva
subfamily_PP2D1_pd Subfamily PP2D1 202-289 2.1e-17 56.0 In-house 187-274 (492) alignment 
Range on Protein: 202-289
Range on HMM: 187-274/492.0
GNELVLANLGDSRAILCRNGKAKRLTNDHDPeYNTTEKERIKAAGGSFTWNSlGKPLVNSVLTMTRS---FGDVTLKRyGVIATPETRSLE
   | .|| |. .|.|||.|||..|| .|.| .|. |..|.. ||.. . .   . ||| .|. ||    .||  ||.  ||  |.|.| .
lgvlyianaGnvqAvLcreGkaiiLtreHtp.rnkkERtRvekagsvvvkse.knglvnGildttRGLGnyGdpkLkk.svipePkttsvk
subfamily_KAPP-like_pd Subfamily KAPP-like 124-283 3.5e-15 48.7 In-house 35-193 (266) alignment 
Range on Protein: 124-283
Range on HMM: 35-193/266.0
LYVGIFDGHAGSMAVDYVHHNLEFHLKFWLER---------EHDLQIVLKNAFEDLNNKLTRYlyfhypetEYEnsGSTATVSLL-RNGNELVL--ANLG
   ..||||||  | |  .. ..  |.  |..          .| . .|.|||.....||  .        |||  |.|||..|. ..|.   |  ||.|
alfavfdGhaGkGaadaakklfpkelekllkstkqddGGdniydqskllenafkevdaklkdf........eye..GatatlalvwsdGqqrylqvanvG

DSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNslgKPLVNSVlTMTRSFGDVTLKRY--GVIATP
|| |.|.|  ..  |. ||  . .  || |||  | . . |   .  .| . ...|..||  .|.   |.|..|
dssaflsrGneslelskdhkak.dpeekqrikddGitlsdn...qtrinGl.avsralGdhfikelniGlisep
subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 127-283 3e-11 35.7 In-house 37-203 (276) alignment 
Range on Protein: 127-283
Range on HMM: 37-203/276.0
GIFDGHAGSMAVDYVHHNLEFHLKFWLE--------------REHDLQIVLKNAFEDLNNKLTRYlyfhypetEYEnsGSTATVSLL-RNGN--------
..||||||  | |  .. .   |. .|.                .| . .|...|.....||  .        |||  |.|||..|. ..|.        
avfdGhaGkGaadaakklfpkelekllksgnysltkqddGGdniydqskllldlfkevdaklkdf........eye..GatatlalvwsdGeeqqqqqqr

ELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNslgKPLVNSVlTMTRSFGDVTLKRY--GVIATP
 |  ||.||| |.|.|  ..  |. ||  . .  ||.|||  | . . |   .  .| . ...|..||  .|.   |.|..|
ylqvanvGdssaflsrGneslelskdhkat.dpeekqrikddGitlsdn...qtrinGl.avsralGdhfikelniGlisep
subfamily_PDP_pd Subfamily PDP 159-275 2.3e-10 33.1 In-house 115-241 (398) alignment 
Range on Protein: 159-275
Range on HMM: 115-241/398.0
LQIVLKNAFEDLNNKLTRYLYFHYPETEYEN------SGSTATVSLLrNGNELVLANLGDSRAILCRN---G--KAKRLTNDHDPEyNTTEKERIKAAGG
.. .||.||..| . ..     . .|.. ..      ||..|...|. .|.|| .|| ||.||.|...   |  .|..|..|.  . |. | ||||..  
vkealkkaFlklDkdistealkklkekslreallvalsGacallali.egtelhvAntGDcravlgvqeeegsweavkLskdqtad.neeEveRikkeHP

SFTW-NSLGKPLVNSVLTMTRSFGDVTLK
.      . .  . . |. .| |||| .|
geesktvirngRlLgeLqPlRAFGdvryK
subfamily_PPM1H_pd Subfamily PPM1H 164-243 1e-09 30.7 In-house 141-211 (404) alignment 
Range on Protein: 164-243
Range on HMM: 141-211/404.0
KNAFEDLNNKLTRYlyfhypETEYENS-GSTATVSLLrNGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyntTEKERIK
 .|| .......|       ...|. . | || |.|.   . | .|| |||||||.|... . | .|. ||   ||..|..
esaflemDeqiare......reayrikGGCtalvalv.llgklYvanaGDsRailvrkdeiiplsadftPe...teRqRlq
subfamily_TAB1_pd Subfamily TAB1 190-275 1.7e-09 29.9 In-house 129-213 (333) alignment 
Range on Protein: 190-275
Range on HMM: 129-213/333.0
SGSTATVSLLRNgNELVLANLGDSRAILCR---NGKAKRLTNDHDPEyNTTEKERIKAAGgsFTWNSLGKPLVNSVLTMTRSFGDVTLK
 |.|| | |. | |.|  || |||||.|..   . | | |  ||. . |  | .|.|  |  .  . . .  . .    ||| || ..|
gGttAvvalifn.nkLyVaNvGdsrAllvkrkesekvkqLsvdHttd.NedEllRlkdLG..ldieqikrnkrlgskentRsiGdykvk
PP2C_SIG_SM00331 111-229 1e-07 24.8 In-house 18-126 (217) alignment 
Range on Protein: 111-229
Range on HMM: 18-126/217.0
EDRICIKELHPNLLYVGIFDGHA-GSMAVDYVHHNLEFHLKFWLERehdlqivlkNAFEDLNNKLTR----YlyfhypeTEYENSGSTATVSLL-RNGNE
.|  .. .|.   | . ..||.  |  |  .    ..   ... |.         ...... ..| |            .| .... |... |.  ....
GDyydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellseg.........eelsqalkrlnraiyee.......keekgmfaTlllalydfssgk

LVLANLGDSRAILCRNGKAKRLTND
| .||.|||| .| |.|| .  . |
lsyanaGdsrpyllrdgklveilkd
Subfamily Dicty-PPM1L-like 205-253 4.8e-07 21.9 In-house 229-276 (305) alignment 
Range on Protein: 205-253
Range on HMM: 229-276/305.0
LVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNS
||.|. .|.. .|...|... | ... .| .  |. |.|  ..   |. 
lvvakanDqflvlatdGlwevlsyqdvve.evkellrdkssqkkiewdf
PP2C_2 Protein phosphatase 2C 104-266 9.5e-07 21.3 Pfam-A 6-174 (212) alignment 
Range on Protein: 104-266
Range on HMM: 6-174/212.0
IGRRAENEDRICIKELHPNLLYVgIFDGHAGS----MAVDYVHHNLEFHLKFWLEREHDLQivLKNAFEDLNNKLTRYL----YFHYPETEYENSGSTAT
. ... ..|.. |.| .   | . . ||.        .  .. ...  .|. .||.|   .   . ......|.. . .      .  . | .. ..| .
rrkgkpcqDalaireasdgwlla.VADGaGsakrSdkGarlaveaagealeklleeeseqe..eeallrqieneilasvklkqeaeaqqeelkdyatTll

VSLlRNGNELVLANLGDSRA-ILCRNGKAKRLTNDHDPEY-NTTEKERIKAAGGSFTWNSLGKPLVNSVLTMT
. . ....|.|....||... .  |.|....|. ..  || |.|   . ..|.... ...| .. .. .| ||
lav.itpgeivffqiGDgaivvrdrdgevqllgepdsgeyanettfltsedaeeelrirrlklepgdalllmT
PP2C_2 Protein phosphatase 2C 104-266 9.5e-07 21.3 In-house 6-174 (212) alignment 
Range on Protein: 104-266
Range on HMM: 6-174/212.0
IGRRAENEDRICIKELHPNLLYVgIFDGHAGS----MAVDYVHHNLEFHLKFWLEREHDLQivLKNAFEDLNNKLTRYL----YFHYPETEYENSGSTAT
. ... ..|.. |.| .   | . . ||.        .  .. ...  .|. .||.|   .   . ......|.. . .      .  . | .. ..| .
rrkgkpcqDalaireasdgwlla.VADGaGsakrSdkGarlaveaagealeklleeeseqe..eeallrqieneilasvklkqeaeaqqeelkdyatTll

VSLlRNGNELVLANLGDSRA-ILCRNGKAKRLTNDHDPEY-NTTEKERIKAAGGSFTWNSLGKPLVNSVLTMT
. . ....|.|....||... .  |.|....|. ..  || |.|   . ..|.... ...| .. .. .| ||
lav.itpgeivffqiGDgaivvrdrdgevqllgepdsgeyanettfltsedaeeelrirrlklepgdalllmT
subfamily_PHLPP_pd Subfamily PHLPP 112-286 1.4e-06 20.4 In-house 17-181 (246) alignment 
Range on Protein: 112-286
Range on HMM: 17-181/246.0
DRICIKELHPNLLYvGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHDLQIVLKNAFEDLNNKLTrylyfhypeTEYENSGSTATVSLLRNGN-------E
.. |...|. . || |.|||.. .     . . ..  ||  ...... .  .|| .   ..||          .. |  ||.| . |.|. .        
nklcvaalsvealy.GlfdGdrneelssllqrlmkdvlkeevqkdkneeeymkntllvaqrklG.........eaGeklgsaallilirhdkvdPaksfs

LVLANLGDSRAILCRNGKAKRLTNDHDPEYNttEKERIKAAGGSFTWNSlgKplVNSVLTMTRSFGDVTLKRYgVIATPETR
| .|. |   |.|.||||  ||.. .  | .  | .||| | .  | ..  |  .|.|.. || .| . |  . |. .|. |
LevAsvGtlqavliRngkklrlsksyviekd..elkrikeakaiitedn..k..ingviestrllGytflfPv.vlPkphvr
subfamily_PPM1G_pd Subfamily PPM1G 101-175 4.2e-06 19.0 In-house 24-100 (473) alignment 
Range on Protein: 101-175
Range on HMM: 24-100/473.0
DSLIGRRAENEDR-ICIKELHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWL-EREHDLQIVLKNAFEDLNNKLT
 .  | |...||   || .|. .    ...||| |.    || ..|   ||     .| |..  |..|| .|..||.
samqGwrvsqEDahncitdldedtslfavyDGHGGkevakyvakklpdllkaqkgykegdvekaleeaflalDeklk