Gene PPM1K-1 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PPM1K
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP190_AA protein Get Run
SpurP190_AA_94-289 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPM1K_pd Subfamily PPM1K 97-290 1.1e-112 368.5 In-house 5-197 (263) alignment
Range on Protein: 97-290
Range on HMM: 5-197/263.0
RIGKDSLIGRRAENEDRICIKELHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHDLQIVLKNAFEDLNNKLTRYLYFHYPETEYENSGSTATV
 .|||||||.||||||||..|||.|.||||..|||||||.|.|.||..||..||..||.|.||.||||||||.|..||.|||.|...|.|...||.||||
svGkdsliGkraenedriklkeldpellyvavfdGhaGsaaadfvhdklekilkrllekekdleivlknafeeldkklkrylefsvaeaellssGttatv

SLLRNGNELVLANLGDSRAILCRNGKAKRLTNDHDPEYNTtEKERIKAAGGSFTWNSLGKPLVNSVLTMTRSFGDVTLKRYGVIATPETRSLEV
||||.|.|||||.|||||||||||||||.||.|||||... |||||||||||..||||||||||..|.||||.||..||||||||||||.||.|
sllrdGtelvlaslGdsrailcrnGkakkltrdhdPelee.ekerikaagGsvewnslgkplvngrlamtrslGdldlkryGviatPetkslkv

0034914 PP2C-like 95-289 4.3e-44 143.6 In-house 20-224 (295) alignment
Range on Protein: 95-289
Range on HMM: 20-224/295.0
VGRIGKDSLIGRRAENEDRICIKE----LHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLER--------EHDLQIVLKNAFEDLNNKLTRYLYFhy
. |.|  | .||| .|||....      |...||..|.|||| |. | ......|  .|. .||.        ..|.. .|..||  ....| ....   
llrvgvasdqGrrksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelall..

pETEYENSGSTATVSLLrNGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWnslgkPLVNSVLTMTRSFGDVTLK-------
 . |. .||.||.| |.  || |..||.|||||.|.|||....||.||.|  | .|.|||..|||  ..     . || || .||..||. ||       
.rpelagsGtTavvali.rgnklyvanvGDSravllrngelvqltvdhkpv.nelererilsaggavsh.....grvngvlavtRalGdfdlklllslll

-RYGVIATPETRSLE
 ...|.|.|....||
leplvsaePdvtvle

PP2Cc_SM00332 99-287 6.4e-40 130.2 In-house 13-206 (274) alignment
Range on Protein: 99-287
Range on HMM: 13-206/274.0
GKDSLIGRRAENEDRICIKEL---HPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD-----LQIVLKNAFEDLNNKLTRYLYFHYPETeyENS
||.|  |.| ..||.....     . . |..|.||||.|| ....|  .|  .||  |. . |      . .||.||........     . .|   ..|
gkssmqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen..als

GSTATVSLLRNGNeLVLANLGDSRAILCRNGKAKRLTNDHDPeYNTTEKERIKAAGGSFTWNslgkpLVNSVLTMTRSFGDVTLKR------YGVIATPE
||||.|.||.... |..||.|||||.|||||||..|..|| |  . .|..|||.|||.  ..      || .| ..|.|||. ||.       ...|.|.
Gstavvallkked.lyvanvGDSravlcrngkavqlsvdhkp.edederkRikkaggvvekg.....rvngglavsrafGdhflkknkklkepyitaepd

TRS
.  
vkv

PP2C Protein phosphatase 2C 102-288 3.9e-38 124.5 Pfam-A 7-196 (255) alignment
Range on Protein: 102-288
Range on HMM: 7-196/255.0
SLIGRRAENEDRICIKE------LHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD--LQIVLKNAFED-LNNKLTRylyfHYPETEYENSGS
.| |.| ..||.... .         .  ....||||.|..| .| . .|| .||   . . .  .. .|...|.  ....|..    .   || ..|||
elqgarksmedahialknlekssgkssvaffavfdghggreaakyarehleeilkeqksflelekvekalrksfladtdeelks....skantepsksGs

TATVSLLRNGNeLVLANLGDSRAILCRNGKAK-RLTNDHDPEyNTTEKERIKAAGGSFTWnslgKPLVNSVLTMTRSFGDVTLKR---YGVIATPETRSL
||.|.|.|. . | .||.|||||.|||...|| .||.||.|. .. |.|||..||||. .    .  || .| ..|..||. ||.   . |.| |...| 
tavvalirgkk.lyvAnvGDSravLcrkdnakkeltedHkps.dedEreRIeeaggsvsn....ngrvngsLavsRalGdfelkpkeeqlvsaePdvtsv





PP2C Protein phosphatase 2C 102-288 3.9e-38 124.5 In-house 7-196 (255) alignment
Range on Protein: 102-288
Range on HMM: 7-196/255.0
SLIGRRAENEDRICIKE------LHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD--LQIVLKNAFED-LNNKLTRylyfHYPETEYENSGS
.| |.| ..||.... .         .  ....||||.|..| .| . .|| .||   . . .  .. .|...|.  ....|..    .   || ..|||
elqgarksmedahialknlekssgkssvaffavfdghggreaakyarehleeilkeqksflelekvekalrksfladtdeelks....skantepsksGs

TATVSLLRNGNeLVLANLGDSRAILCRNGKAK-RLTNDHDPEyNTTEKERIKAAGGSFTWnslgKPLVNSVLTMTRSFGDVTLKR---YGVIATPETRSL
||.|.|.|. . | .||.|||||.|||...|| .||.||.|. .. |.|||..||||. .    .  || .| ..|..||. ||.   . |.| |...| 
tavvalirgkk.lyvAnvGDSravLcrkdnakkeltedHkps.dedEreRIeeaggsvsn....ngrvngsLavsRalGdfelkpkeeqlvsaePdvtsv





PPM_PTC7 105-287 9.2e-38 123.1 In-house 10-200 (259) alignment
Range on Protein: 105-287
Range on HMM: 10-200/259.0
GRRAENEDRICIKE------LHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD--LQIVLKNAFED--LNNKLTRylyfHYPETEYENSGSTA
|.| ..||. ...          .  ....||||.|..| .|.. .|| .||   . | .  |. .|...|.   ....|..    .   || ..|||||
gfrksmedahialanlesssgkdsvaffavfdghggreaakyarehleeilkerksfeeleklekalrksflaldtdeelks....seantepstsGstA

TVSLLRNGNeLVLANLGDSRAILCRNGKAK-RLTNDHDPEyNTTEKERIKAAGGSFTWNslGKPLVNSVLTMTRSFGDVTLKR-----YGVIATPETRS
.| |... . |  ||.|||||.|||.|.|. .||.||.|. |. |.|||..||||. .   |.  || || ..|.|||. ||.       |.|.|.. |
vvalitgsk.lyvAnvGDSravLcrsgnavkqltedHkps.nedEreRiegaggsvsnv..gngrvngvlavsRafGdfelkpketeeqlvsaePdiss

subfamily_PPM1A_pd Subfamily PPM1A 97-277 1.2e-33 109.7 In-house 13-195 (282) alignment
Range on Protein: 97-277
Range on HMM: 13-195/282.0
RIGKDSLIGRRAENEDRICIKELHPNL---LYVGIFDGHAGSMAVDYVHHNLEFHLKF---------WLEREHDLQIVLKNAFEDLNNKLTRYlyFHYPE
|.| .|  |.|.|.||. ..    ..|    .  .||||||| ...||...|  ..             . ..... .|...| .|.... .   ..  .
rygvssmqgwrvemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenileeeelkeaaleasekdevkealrqgfLaldeairel..stdlk

TEyENSGSTATVSLLRnGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTwnslgKPLVNSVLTMTRSFGDVTLKRY
|. ..|||||.. |..  ..|..||||||||.|||||||..||.|| |. ...||.||..|||| .     .  ||  | ..|..|| ..|. 
ta.dksGsTavtvlvs.ekhliianlGDsRavlcrngkaaflteDHkps.rpkEkkRieqAGGsvv.....vsRvnGaLAvsRalGDyeykee

0049733 PP2C-like 99-285 2.6e-31 101.9 In-house 6-170 (235) alignment
Range on Protein: 99-285
Range on HMM: 6-170/235.0
GKDSLIGR-RAENEDRICIkelhpNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLERE--HDLQIVLKNAFEDLNNKLTRYLYFHYpetEYENSGSTAT
|  | ||| | .|||....     .||.....||| |. | ... ..|  .|. .|..   .||. .|..||. .|. | .. . ..   |.  .|.||.
gaasdigrvrkvneDavlv.....glllfavaDGhgghaagevasellvetllelllelllldleealrkaflaaneallelalasp...elagmgtTav

VSLLRnGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFtwnslgkpLVNSVLTMTRSFGDVTLKrygviatPET
| ||. |. |..||.|||||.|.|.||. .|| || |  | .|..||..||| .         |. .| .||..|| .||       |..
valld.ggklyvanvGDsrayllrdgklvqltedhspv.nelerqriitaggav........rvpgrlaltralGdlllk.......pdv

subfamily_PPM1G2_pd Subfamily PPM1G2 99-278 3.8e-29 94.5 In-house 22-196 (287) alignment
Range on Protein: 99-278
Range on HMM: 22-196/287.0
GKDSLIGRRAENEDRICI------KELHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLE-REHDLQIVLKNAFEDLNNKLTRYlyfhyPETEYENSG
|  .. | | . ||   .      |. ...| ....|||| |. .  |. ..|   ..   . .|  |. .||.|| .....|..       ... |..|
gssamqGyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkd.....eklkdesaG

STATVSLLRNGNeLVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNSlgkplVNSVLTMTRSFGDVTLKRYG
|||.| |... . |. || |||||.|. .|..| |. || |. ...||.||.||||    |      || .| . |..|| . |.  
stavvvlikeek.lyvanaGDsravlsskgnvkalsfDhkPq.eesekkriiaagGfvelnr.....vngnLalsralgDfefkknv

subfamily_PPM1E_pd Subfamily PPM1E 121-288 4.1e-29 94.6 In-house 38-195 (265) alignment
Range on Protein: 121-288
Range on HMM: 38-195/265.0
PNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHDLQIVLKNAFEDLNNKLTRYlyfhyPETEYENSGSTATVSLLRNgNELVLANLGDSRAILCRN
..  . ..||||.|. | .|  ..|  .|    . ..| .  ||.||. .......       | |  .||||| | |... ..| .| ||||.|.|.|.
keraffavfDGHgGveaakyaaahlhellvrqeklkedpaealkeafkltDerflqk.....aereklksGstavvvliek.dqlyvaWlGDsqallvrk

GKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNslGKPLVNSVLTMTRSFGDVTLKRYgVIATPETRSL
|.| .|.. | || .  ||.||..|||   .   |.  || ||...|. |||.||.| |.. ... ..
geavqlmkpHkPe.redEkkRieeagGlvvvi..gawRvnGvLsvsRaiGDvklkpy.vsgeadvaev

subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 97-284 1.9e-28 92.4 In-house 7-186 (255) alignment
Range on Protein: 97-284
Range on HMM: 7-186/255.0
RIGKDSLIGRRAENEDRICIKEL---HPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD-LQIVLKNAFEDLNNKLtrylyfhypeTEY-ENSG
..|.  .||||.  ||.. |      ...  |. .||||.|. | ..  ..|.  |.  |. ..   . .||.|..... ..          .|.    |
kvgfsdmiGrrptmedelviyGsfrdksdedyyalfdGhgGraaakfaseelykilaelldlnnanPvkslkkaykeistqi..........serpkfiG

STATvSLLRNGNELVLANLGDSRAILC-RNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNsLGKPLVNSVLTMTRSFGDVTLKRYgVIATPE
.||. |.|  ..  ..||.||||..|| ..| ||||. || |  .  |..||...||    .      ||  |...|..||. |. . |.. |.
ttaa.svliiedkvyianvGdsrvvlcqkdgtakrlsldhkPs.eeseekriselGGtvvst.vvtsrvnGtlavsralGdsflePf.vvpdPd

subfamily_PPM1L_pd Subfamily PPM1L 102-288 3.9e-25 81.6 In-house 11-202 (269) alignment
Range on Protein: 102-288
Range on HMM: 11-202/269.0
SLIGRRAENEDRICIKELHPN---LLYVGIFDGHAGSMAVDYVHHNLEFHLKFWL-----EREHDLQIVLKNAFEDLNNKLTrYLYFHYPETEYENSGST
|. ||| . |||. |.|   |     ....|||| | .| ..... |   .|  |     ..|. . |  .. ..|    .  .   .  ..... .|.|
svlGrrprmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentepinfsklltdeilsvd.ekllekakraediaGtt

ATVSLLRnGNELVLANLGDSRAILC-RNGKAKRLTNDHDPeYNTTEKERIKAAGGSFTWNslGKPLVNSVLTMTRSFGDVTLKRYG-VIATPETRSL
| ..|.. ...|..||.|||| .|. ..|||  |. || | ..  |. ||| |||  ...  |   |. ||...|..||  ||    |||.|.  ..
alialvq.esdlivanvGdsrGvlydkrGkaiplsfdhkp.qqvkerkrikkaGGfiafr..GvwrvaGvlatsralGdyplkdknlviadpdiltf

subfamily_ILKAP_pd Subfamily ILKAP 123-288 1.1e-23 76.8 In-house 43-210 (293) alignment
Range on Protein: 123-288
Range on HMM: 43-210/293.0
LLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEReHDLQI---VLKNAFED-LNNKLTRYLYFHYPETEYENSGSTATVSLLRNgNELVLANLGDSRAILC
. | ..||||||| | ... ..|. ...  | . .|..     .|... |  ...   .|     ..     |||||| |  . | |  ||||||.|.|.
vsyyavfdGhaGsrasefaaeklhkkileklpk.sdvsakekeikkclvdsfkktdeefLklaskakPvWkdGstatvvlvld.nvlyvanlGdskavlv

RNGKAKR------LTNDHDPEyNTTEKERIKAAGGSFTWNSlgkplVNSVLTMTRSFGDVTLKRYGVIATPETRSL
|. .. .      || ||.|  .  |..||. |||. . .      |. || ..|| ||   || |||.||... .
rkkeegdkiasvvLtkdhtpv.kyeerkriqkaGgvvrdgr.....vlGvlevsrsiGdgrfkrlGvistPdvkkc

subfamily_PPM1G_pd Subfamily PPM1G 184-276 1.2e-22 73.6 In-house 290-376 (473) alignment
Range on Protein: 184-276
Range on HMM: 290-376/473.0
ETEYENSGSTATVSLLRnGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNSlgKplVNSVLTMTRSFGDVTLKR
|.. |.||.||.| ||. ...|. || ||||..|.|||||  |  || || . .|.|||..|||  . .   .  ||  | . | .|| . |.
eepGedsGttAvvaLlk.ekklivAnaGDsRcvlsrnGkAldlslDHkPe.DevEleRiekAGGkvdedg..R..vnGGLnlsRAlGDhaYkk

subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 106-285 1.3e-22 73.7 In-house 3-196 (292) alignment
Range on Protein: 106-285
Range on HMM: 3-196/292.0
RRAENEDRICIKELHPNLLY-VGIFDGHA--GSMAVDYVHHNLEFHLKFWLEREHDLQIVLKNAFEDLNNKLTRYlYFhypeTEYENSGSTATVSLLRNG
 . ||.|| .. |    | .   ..|||   |    ..   .|| .|     .  .|   | .   |.  || .  .      . |....... .  |..
nkkenqdrfllvegsealtflaavldGhGvnGdkvaqlaedtlevelleltrqlqelsealllrildiaakldkl.ti....daresattavvcarvrdd

NELVLANLGDSRAILCR-----NGKAKRLTNDHDPEyNTTEKERIKAAGGSFT------WNSLGKPLV------NSVLTMTRSFGDVTLKRYGVIATPET
 .|.|||.|||||.| |     . . . |..|| || .  |..||..|||  .      |   | . |      .  |...|. ||. |.  ||.| || 
ralilanvGdsrallgrclggsdyeliPlsrdhkPe.dPderarilraGGrveptrvrgwgfrGtarvwrrrqqeGdlalsralGdfhlfeaGvvaePel





PPM_PTC7_SpoIIE 105-276 5.3e-20 65.2 In-house 10-162 (230) alignment
Range on Protein: 105-276
Range on HMM: 10-162/230.0
GRRAENEDRICIKE------LHPNLLYVGIFDGHAGSMavDYVHHNLEFHLKFWLEREHD-LQIVLKNAFEDLNNKLTRYlyfhypeteYENSGSTATVS
|.| ..||. ...        .   |.||..||| |..   ...  |   |.    .... .  .|..... |. .|. .          ..||.||.| 
garksmedahispansekssggrlalvvgdvdGhGgra..alamgllrtalrelafaglekpeeilrrlnlalaadlede.........psssgaTavva

LLRNGN-ELVLANLGDSRAILCRN-GKakrltndhdpeynttEKERIkAAGGSFTwNSLGKPLVNSVLTMTRSFGDVTLKR
|... . .| .||.|||...|.|. |.               |.||| .|||     ...   |. ||......||. |. 
lidpstgklyvanaGdsppllvrddgg...............ereri.vagglps.lGilpgrvfgvlavslapGdlllly

subfamily_PPM1D_pd Subfamily PPM1D 105-250 1.9e-19 62.9 In-house 11-172 (309) alignment
Range on Protein: 105-250
Range on HMM: 11-172/309.0
GRRAENEDRICIKELH------PNLLYVGIFDGHAGSMAVDYVHHNLEFHL----KFWLEREHDLQIVLKNAFEDLNNKLTRYlYFHYPETE---YENSG
| |   ||...|.  .       .  .|..|||| |  |  .....|   .    ||. . ..|..  ...|| ...... .  . ..|.|.   .  .|
GgrkymeDvvaivleeeesaeelevafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkk.leeWpktksgllstaG

STATVSLLRNgNELVLANLGDSRAILCRNGK------AKRLTNDHDPEYnTTEKERIKAAGGSFT
.||.| ..|. ..| .|. |||...|  . .      || ||.|| ||   .|||||. .||. .
ttasvviirr.eklyvahvGDsaivlgvkepkekklrakeltkdHkPes.peekerieelGGeva

subfamily_PP2D1_pd Subfamily PP2D1 202-289 2.1e-17 56.0 In-house 187-274 (492) alignment
Range on Protein: 202-289
Range on HMM: 187-274/492.0
GNELVLANLGDSRAILCRNGKAKRLTNDHDPeYNTTEKERIKAAGGSFTWNSlGKPLVNSVLTMTRS---FGDVTLKRyGVIATPETRSLE
   | .|| |. .|.|||.|||..|| .|.| .|. |..|.. ||.. . .   . ||| .|. ||    .||  ||.  ||  |.|.| .
lgvlyianaGnvqAvLcreGkaiiLtreHtp.rnkkERtRvekagsvvvkse.knglvnGildttRGLGnyGdpkLkk.svipePkttsvk

subfamily_KAPP-like_pd Subfamily KAPP-like 124-283 3.5e-15 48.7 In-house 35-193 (266) alignment
Range on Protein: 124-283
Range on HMM: 35-193/266.0
LYVGIFDGHAGSMAVDYVHHNLEFHLKFWLER---------EHDLQIVLKNAFEDLNNKLTRYlyfhypetEYEnsGSTATVSLL-RNGNELVL--ANLG
   ..||||||  | |  .. ..  |.  |..          .| . .|.|||.....||  .        |||  |.|||..|. ..|.   |  ||.|
alfavfdGhaGkGaadaakklfpkelekllkstkqddGGdniydqskllenafkevdaklkdf........eye..GatatlalvwsdGqqrylqvanvG

DSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNslgKPLVNSVlTMTRSFGDVTLKRY--GVIATP
|| |.|.|  ..  |. ||  . .  || |||  | . . |   .  .| . ...|..||  .|.   |.|..|
dssaflsrGneslelskdhkak.dpeekqrikddGitlsdn...qtrinGl.avsralGdhfikelniGlisep

subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 127-283 3e-11 35.7 In-house 37-203 (276) alignment
Range on Protein: 127-283
Range on HMM: 37-203/276.0
GIFDGHAGSMAVDYVHHNLEFHLKFWLE--------------REHDLQIVLKNAFEDLNNKLTRYlyfhypetEYEnsGSTATVSLL-RNGN--------
..||||||  | |  .. .   |. .|.                .| . .|...|.....||  .        |||  |.|||..|. ..|.        
avfdGhaGkGaadaakklfpkelekllksgnysltkqddGGdniydqskllldlfkevdaklkdf........eye..GatatlalvwsdGeeqqqqqqr

ELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNslgKPLVNSVlTMTRSFGDVTLKRY--GVIATP
 |  ||.||| |.|.|  ..  |. ||  . .  ||.|||  | . . |   .  .| . ...|..||  .|.   |.|..|
ylqvanvGdssaflsrGneslelskdhkat.dpeekqrikddGitlsdn...qtrinGl.avsralGdhfikelniGlisep

subfamily_PDP_pd Subfamily PDP 159-275 2.3e-10 33.1 In-house 115-241 (398) alignment
Range on Protein: 159-275
Range on HMM: 115-241/398.0
LQIVLKNAFEDLNNKLTRYLYFHYPETEYEN------SGSTATVSLLrNGNELVLANLGDSRAILCRN---G--KAKRLTNDHDPEyNTTEKERIKAAGG
.. .||.||..| . ..     . .|.. ..      ||..|...|. .|.|| .|| ||.||.|...   |  .|..|..|.  . |. | ||||..  
vkealkkaFlklDkdistealkklkekslreallvalsGacallali.egtelhvAntGDcravlgvqeeegsweavkLskdqtad.neeEveRikkeHP

SFTW-NSLGKPLVNSVLTMTRSFGDVTLK
.      . .  . . |. .| |||| .|
geesktvirngRlLgeLqPlRAFGdvryK

subfamily_PPM1H_pd Subfamily PPM1H 164-243 1e-09 30.7 In-house 141-211 (404) alignment
Range on Protein: 164-243
Range on HMM: 141-211/404.0
KNAFEDLNNKLTRYlyfhypETEYENS-GSTATVSLLrNGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyntTEKERIK
 .|| .......|       ...|. . | || |.|.   . | .|| |||||||.|... . | .|. ||   ||..|..
esaflemDeqiare......reayrikGGCtalvalv.llgklYvanaGDsRailvrkdeiiplsadftPe...teRqRlq

subfamily_TAB1_pd Subfamily TAB1 190-275 1.7e-09 29.9 In-house 129-213 (333) alignment
Range on Protein: 190-275
Range on HMM: 129-213/333.0
SGSTATVSLLRNgNELVLANLGDSRAILCR---NGKAKRLTNDHDPEyNTTEKERIKAAGgsFTWNSLGKPLVNSVLTMTRSFGDVTLK
 |.|| | |. | |.|  || |||||.|..   . | | |  ||. . |  | .|.|  |  .  . . .  . .    ||| || ..|
gGttAvvalifn.nkLyVaNvGdsrAllvkrkesekvkqLsvdHttd.NedEllRlkdLG..ldieqikrnkrlgskentRsiGdykvk

PP2C_SIG_SM00331 111-229 1e-07 24.8 In-house 18-126 (217) alignment
Range on Protein: 111-229
Range on HMM: 18-126/217.0
EDRICIKELHPNLLYVGIFDGHA-GSMAVDYVHHNLEFHLKFWLERehdlqivlkNAFEDLNNKLTR----YlyfhypeTEYENSGSTATVSLL-RNGNE
.|  .. .|.   | . ..||.  |  |  .    ..   ... |.         ...... ..| |            .| .... |... |.  ....
GDyydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellseg.........eelsqalkrlnraiyee.......keekgmfaTlllalydfssgk

LVLANLGDSRAILCRNGKAKRLTND
| .||.|||| .| |.|| .  . |
lsyanaGdsrpyllrdgklveilkd

Subfamily Dicty-PPM1L-like 205-253 4.8e-07 21.9 In-house 229-276 (305) alignment
Range on Protein: 205-253
Range on HMM: 229-276/305.0
LVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNS
||.|. .|.. .|...|... | ... .| .  |. |.|  ..   |. 
lvvakanDqflvlatdGlwevlsyqdvve.evkellrdkssqkkiewdf

PP2C_2 Protein phosphatase 2C 104-266 9.5e-07 21.3 Pfam-A 6-174 (212) alignment
Range on Protein: 104-266
Range on HMM: 6-174/212.0
IGRRAENEDRICIKELHPNLLYVgIFDGHAGS----MAVDYVHHNLEFHLKFWLEREHDLQivLKNAFEDLNNKLTRYL----YFHYPETEYENSGSTAT
. ... ..|.. |.| .   | . . ||.        .  .. ...  .|. .||.|   .   . ......|.. . .      .  . | .. ..| .
rrkgkpcqDalaireasdgwlla.VADGaGsakrSdkGarlaveaagealeklleeeseqe..eeallrqieneilasvklkqeaeaqqeelkdyatTll

VSLlRNGNELVLANLGDSRA-ILCRNGKAKRLTNDHDPEY-NTTEKERIKAAGGSFTWNSLGKPLVNSVLTMT
. . ....|.|....||... .  |.|....|. ..  || |.|   . ..|.... ...| .. .. .| ||
lav.itpgeivffqiGDgaivvrdrdgevqllgepdsgeyanettfltsedaeeelrirrlklepgdalllmT

PP2C_2 Protein phosphatase 2C 104-266 9.5e-07 21.3 In-house 6-174 (212) alignment
Range on Protein: 104-266
Range on HMM: 6-174/212.0
IGRRAENEDRICIKELHPNLLYVgIFDGHAGS----MAVDYVHHNLEFHLKFWLEREHDLQivLKNAFEDLNNKLTRYL----YFHYPETEYENSGSTAT
. ... ..|.. |.| .   | . . ||.        .  .. ...  .|. .||.|   .   . ......|.. . .      .  . | .. ..| .
rrkgkpcqDalaireasdgwlla.VADGaGsakrSdkGarlaveaagealeklleeeseqe..eeallrqieneilasvklkqeaeaqqeelkdyatTll

VSLlRNGNELVLANLGDSRA-ILCRNGKAKRLTNDHDPEY-NTTEKERIKAAGGSFTWNSLGKPLVNSVLTMT
. . ....|.|....||... .  |.|....|. ..  || |.|   . ..|.... ...| .. .. .| ||
lav.itpgeivffqiGDgaivvrdrdgevqllgepdsgeyanettfltsedaeeelrirrlklepgdalllmT

subfamily_PHLPP_pd Subfamily PHLPP 112-286 1.4e-06 20.4 In-house 17-181 (246) alignment
Range on Protein: 112-286
Range on HMM: 17-181/246.0
DRICIKELHPNLLYvGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHDLQIVLKNAFEDLNNKLTrylyfhypeTEYENSGSTATVSLLRNGN-------E
.. |...|. . || |.|||.. .     . . ..  ||  ...... .  .|| .   ..||          .. |  ||.| . |.|. .        
nklcvaalsvealy.GlfdGdrneelssllqrlmkdvlkeevqkdkneeeymkntllvaqrklG.........eaGeklgsaallilirhdkvdPaksfs

LVLANLGDSRAILCRNGKAKRLTNDHDPEYNttEKERIKAAGGSFTWNSlgKplVNSVLTMTRSFGDVTLKRYgVIATPETR
| .|. |   |.|.||||  ||.. .  | .  | .||| | .  | ..  |  .|.|.. || .| . |  . |. .|. |
LevAsvGtlqavliRngkklrlsksyviekd..elkrikeakaiitedn..k..ingviestrllGytflfPv.vlPkphvr

subfamily_PPM1G_pd Subfamily PPM1G 101-175 4.2e-06 19.0 In-house 24-100 (473) alignment
Range on Protein: 101-175
Range on HMM: 24-100/473.0
DSLIGRRAENEDR-ICIKELHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWL-EREHDLQIVLKNAFEDLNNKLT
 .  | |...||   || .|. .    ...||| |.    || ..|   ||     .| |..  |..|| .|..||.
samqGwrvsqEDahncitdldedtslfavyDGHGGkevakyvakklpdllkaqkgykegdvekaleeaflalDeklk