Phosphatase Subfamily PXYLP1
PXYLP1 is found in bilateria.
PXYLP1 has a N-terminal transmembrane region and C-terminal phosphatase domain.
Human PXYLP1 dephosphorylates xylose, a sugar, in the glycosaminoglycan-protein linkage region of proteoglycans . In collaboration with kinase FAM20B, it regulates the transient phosphorylation of the Xyl residue in the glycosaminoglycan-protein linkage region, which controls the formation of glycosaminoglycan chains of proteoglycans .