Difference between revisions of "Phosphatase Family PAP"
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PAP ('''P'''urple '''A'''cid '''P'''hosphatase is found in most eukaryotes, even in some prokaryotes. It has three eukaryotic subfamilies, the first two present in human: | PAP ('''P'''urple '''A'''cid '''P'''hosphatase is found in most eukaryotes, even in some prokaryotes. It has three eukaryotic subfamilies, the first two present in human: | ||
| − | * [[Phosphatase_Subfamily_ACP5|ACP5]] is found in most eukaryotes. Human ACP5 hydrolyzes a variety of phosphomonoesters at | + | * [[Phosphatase_Subfamily_ACP5|ACP5]] is found in most eukaryotes. Human ACP5 hydrolyzes a variety of phosphomonoesters at acidic pH in vitro. It also shows phosphatase activity towards the protein osteopontin, and the mannose 6-phosphate modification on lysosomal proteins. |
* [[Phosphatase_Subfamily_PAPL|PAPL]] is found in holozoa, but is lost in most arthropods. Its function is unclear. | * [[Phosphatase_Subfamily_PAPL|PAPL]] is found in holozoa, but is lost in most arthropods. Its function is unclear. | ||
| − | * [[Phosphatase_Subfamily_DCR2|DCR2]] is present in most fungi, most plants and some | + | * [[Phosphatase_Subfamily_DCR2|DCR2]] is present in most fungi, most plants and some chromalveolates. |
Latest revision as of 00:56, 9 May 2016
Phosphatase Classification: Fold PPPL: Superfamily PPPL: Family PAP (purple acid phosphatase)
PAP (Purple Acid Phosphatase is found in most eukaryotes, even in some prokaryotes. It has three eukaryotic subfamilies, the first two present in human:
- ACP5 is found in most eukaryotes. Human ACP5 hydrolyzes a variety of phosphomonoesters at acidic pH in vitro. It also shows phosphatase activity towards the protein osteopontin, and the mannose 6-phosphate modification on lysosomal proteins.
- PAPL is found in holozoa, but is lost in most arthropods. Its function is unclear.
- DCR2 is present in most fungi, most plants and some chromalveolates.
