Difference between revisions of "Phosphatase Family MDP1"
From PhosphataseWiki
(Created page with "MDP1 has been reported as a putative tyrosine phosphatase <cite>Peisach04</cite>. However, a later study reported that it is a protein-fructosamine-6-phosphatase potentially i...") |
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− | MDP1 has been reported as a putative tyrosine phosphatase <cite>Peisach04</cite>. However, a later study reported that it is a protein-fructosamine-6-phosphatase potentially involved in glycation repair <cite>Fortpied06</cite>. | + | MDP1 gene is the only member in this family. The gene has been reported as a putative tyrosine phosphatase <cite>Peisach04</cite>. However, a later study reported that it is a protein-fructosamine-6-phosphatase potentially involved in glycation repair <cite>Fortpied06</cite>. |
Revision as of 05:54, 30 April 2014
MDP1 gene is the only member in this family. The gene has been reported as a putative tyrosine phosphatase [1]. However, a later study reported that it is a protein-fructosamine-6-phosphatase potentially involved in glycation repair [2].
References
- Peisach E, Selengut JD, Dunaway-Mariano D, and Allen KN. X-ray crystal structure of the hypothetical phosphotyrosine phosphatase MDP-1 of the haloacid dehalogenase superfamily. Biochemistry. 2004 Oct 12;43(40):12770-9. DOI:10.1021/bi0490688 |
- Fortpied J, Maliekal P, Vertommen D, and Van Schaftingen E. Magnesium-dependent phosphatase-1 is a protein-fructosamine-6-phosphatase potentially involved in glycation repair. J Biol Chem. 2006 Jul 7;281(27):18378-85. DOI:10.1074/jbc.M513208200 |