Difference between revisions of "Phosphatase Family ArsC"
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| − | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_Cys-based_III|Superfamily Cys-based | + | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_Cys-based_III|Superfamily Cys-based II]]: [[Phosphatase_Family_ArsC|Family ArsC]] |
Arsenate reductase (ArsC) <cite>Bennett</cite>, is only found in prokaryotes. While known to reduce arsenate to arsenite (a similar reaction to the phosphatase reaction), the B. subtilis gene also has in vitro phosphatase activity. | Arsenate reductase (ArsC) <cite>Bennett</cite>, is only found in prokaryotes. While known to reduce arsenate to arsenite (a similar reaction to the phosphatase reaction), the B. subtilis gene also has in vitro phosphatase activity. | ||
Revision as of 01:11, 16 June 2014
Phosphatase Classification: Superfamily Cys-based II: Family ArsC
Arsenate reductase (ArsC) [1], is only found in prokaryotes. While known to reduce arsenate to arsenite (a similar reaction to the phosphatase reaction), the B. subtilis gene also has in vitro phosphatase activity.
Eukaryotes (particularly fungi, plants and protists) have different arsenate reductase, Acr2 of Cys-based II superfamily [2].
Reference
- Bennett MS, Guan Z, Laurberg M, and Su XD. Bacillus subtilis arsenate reductase is structurally and functionally similar to low molecular weight protein tyrosine phosphatases. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13577-82. DOI:10.1073/pnas.241397198 |
- Yeo HK and Lee JY. Crystal structure of Saccharomyces cerevisiae Ygr203w, a homolog of single-domain rhodanese and Cdc25 phosphatase catalytic domain. Proteins. 2009 Aug 1;76(2):520-4. DOI:10.1002/prot.22420 |
