Difference between revisions of "Phosphatase Subfamily CTDSPL2"

Revision as of 05:29, 29 December 2014

Phosphatase Classification: FCP: HSPC129

HSPC129 is also known as HSPC058, and CTDSPL2 (CTD small phosphatase like 2). It has not been well characterized, though in vitro assay showed its phosphatase activity toward CTD. [1].

Evolution

HSPC129 is conserved from Monosiga to human but lost in fruit fly.

Domain Structure

Catalytic activity

Curation notes

Related Kinases

See Phosphorylation of RNA polymerase II C-terminal domain.

References

1. Qian H, Ji C, Zhao S, Chen J, Jiang M, Zhang Y, Yan M, Zheng D, Sun Y, Xie Y, and Mao Y. Expression and characterization of HSPC129, a RNA polymerase II C-terminal domain phosphatase. Mol Cell Biochem. 2007 Sep;303(1-2):183-8. DOI:10.1007/s11010-007-9472-z | PubMed ID:17487459 | HubMed [qian]

Links

Human HSPC129 from NCBI Gene