Difference between revisions of "Phosphatase Subfamily UBLCP1"

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Revision as of 05:33, 29 December 2014

Phosphatase Classification: FCP:UBLCP1

Introduction

UBLCP1 is named after Ubiquitin-like domain containing CTD phosphatase 1. It has an accessary N-terminal domain, similar to ubiquitin. Its function is not well characterized, though in vitro assay showed its phosphatase activity toward RNA polymerase II C-terminal domain [1].

Related Kinases

See Phosphorylation of RNA polymerase II C-terminal domain.

Evolutionary History

It is conserved from Nematostella to human but lost in nematode. However, UBLCP1-like proteins can be found in plant.

Domain Combination

Catalytic activity

It has a different catalytic motif from other subfamilies of FCP.

Curation notes

References

Error fetching PMID 15883030:
  1. Error fetching PMID 15883030: [clone]


Links

Human UBLCP1 from NCBI Gene