Phosphatase Subfamily PPM1G

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Phosphatase Classification: Fold PPM (PP2C): Superfamily PPM (PP2C): Family PPM (PP2C): Subfamily PPM1G

Evolution

PPM1G emerged in holozoa, usually single copy per genome.

Domain

PPM1G has a single structural domain, the phosphatase domain of PPM fold.

Functions

PPM1G inactivates monomeric WWP2 and promotes the assembly of WWP2-WWP1 heterodimeric complex [1].

PPM1G is associated with alcohol use disorder [2].

References

Error fetching PMID 25982659:
  1. Error fetching PMID 25982659: [Ruggeri15]
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