Phosphatase Superfamily Cys-based III

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Phosphatase Classification: Superfamily Cys-based III

The superfamily consists of two member families present in human low molecular weight PTP (LWMPTP) and SSU72. Although human LMWPTP and SSU72 exhibit low sequence identity (15%), the overall folds are very close to each other. The rmsd (root mean square deviation) of 1.7 Å when superimposing SSU72 (PDB ID: 3OMW) with LMWPTP (PDB ID: 1XWW) [1].

Reference

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  1. Error fetching PMID 21204787: [zhangy11]