Phosphatase Subfamily UBLCP1
From PhosphataseWiki
Contents
Phosphatase Classification: FCP:UBLCP1
Introduction
UBLCP1 is named after Ubiquitin-like domain containing CTD phosphatase 1. It has an accessary N-terminal domain, similar to ubiquitin. Its function is not well characterized, though in vitro assay showed its phosphatase activity toward RNA polymerase II C-terminal domain [1].
Related Kinases
See Phosphorylation of RNA polymerase II C-terminal domain.
Evolutionary History
It is conserved from Nematostella to human but lost in nematode. However, UBLCP1-like proteins can be found in plant.
Domain Combination
Catalytic activity
It has a different catalytic motif from other subfamilies of FCP.
Curation notes
References
Error fetching PMID 15883030:
- Error fetching PMID 15883030:
Links
Human UBLCP1 from NCBI Gene
