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From PhosphataseWiki
Welcome to Phosphatase Wiki, a resource for of phosphatases and phosphatase signaling. This is a pilot project for sharing and publication of discoveries that do not fit into traditional publications or haven't yet been polished for publication. Initial content is mostly from the Manning lab at Salk (moved to Genentech in 2012), but we welcome anyone who would like to contribute. Like other wiki's, just go to the login page to request an account.
Introduction to Phosphatases
- Phosphatases and diseases
- Phosphatases as drug targets
- Miscellaneous biological and clinic significance of phosphorylation
- (De)phosphorylation on unusual amino acids: unusual evidence for phosphorylation on histidine, aspartate, cysteine, lysine, and arginine.
- Regulatory subunits: some phosphatases, particularly PPPs, consist of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.
