Phosphatase Subfamily Acr2

Phosphatase Classification: Superfamily Cys-based II: Family CDC25: Subfamily Acr2

Arsenate Reductase

Prokaryotes and eukaryotes use arsenate reductases of distinct folds. E. coli uses ArsC, which belongs to Superfamily Cys-based III, the same as LMWPTP and SSU72. In eukaryotes, particularly fungi, plants and protists, ACR2 exhibit arsenate reductase activity [1]

Reference

1. Yeo HK and Lee JY. Crystal structure of Saccharomyces cerevisiae Ygr203w, a homolog of single-domain rhodanese and Cdc25 phosphatase catalytic domain. Proteins. 2009 Aug 1;76(2):520-4. DOI:10.1002/prot.22420 |