Phosphatase Family ArsC

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Phosphatase Classification: Superfamily Cys-based III: Family ArsC

Arsenate reductase (ArsC) [1], is only found in prokaryotes. While known to reduce arsenate to arsenite (a similar reaction to the phosphatase reaction), the B. subtilis gene also has in vitro phosphatase activity.

Reference

  1. Bennett MS, Guan Z, Laurberg M, and Su XD. Bacillus subtilis arsenate reductase is structurally and functionally similar to low molecular weight protein tyrosine phosphatases. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13577-82. DOI:10.1073/pnas.241397198 | PubMed ID:11698660 | HubMed [Bennett]