Difference between revisions of "Phosphatase Family MDP1"
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Group_HAD|Superfamily HAD]]: [[Phosphatase_Family_MDP1|Family MDP1]] | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Group_HAD|Superfamily HAD]]: [[Phosphatase_Family_MDP1|Family MDP1]] | ||
| − | MDP1 | + | MDP1 is the only human member of this family. It has been reported as a putative tyrosine phosphatase <cite>Peisach04</cite>. However, a later study reported that it is a protein-fructosamine-6-phosphatase potentially involved in glycation repair <cite>Fortpied06</cite>. |
== References == | == References == | ||
Revision as of 23:36, 26 May 2014
Phosphatase Classification: Superfamily HAD: Family MDP1
MDP1 is the only human member of this family. It has been reported as a putative tyrosine phosphatase [1]. However, a later study reported that it is a protein-fructosamine-6-phosphatase potentially involved in glycation repair [2].
References
- Peisach E, Selengut JD, Dunaway-Mariano D, and Allen KN. X-ray crystal structure of the hypothetical phosphotyrosine phosphatase MDP-1 of the haloacid dehalogenase superfamily. Biochemistry. 2004 Oct 12;43(40):12770-9. DOI:10.1021/bi0490688 |
- Fortpied J, Maliekal P, Vertommen D, and Van Schaftingen E. Magnesium-dependent phosphatase-1 is a protein-fructosamine-6-phosphatase potentially involved in glycation repair. J Biol Chem. 2006 Jul 7;281(27):18378-85. DOI:10.1074/jbc.M513208200 |
