Difference between revisions of "Phosphatase Family PAP"
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_MTDP|Fold MTDP]]: [[Phosphatase_Superfamily_MTDP|Superfamily MTDP]]: [[Phosphatase_Family_PAP|Family PAP]] (purple acid phosphatase) | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_MTDP|Fold MTDP]]: [[Phosphatase_Superfamily_MTDP|Superfamily MTDP]]: [[Phosphatase_Family_PAP|Family PAP]] (purple acid phosphatase) | ||
| − | PAP is short for purple acid phosphatase. It has two subfamilies present in human: | + | PAP is short for purple acid phosphatase. The family is found in most eukaryotes, even in some prokaryotes. It has two subfamilies present in human: |
* [[Phosphatase_Subfamily_ACP5|ACP5]]. ACP5 subfamily is found in most eukaryotes. Human ACP5 hydrolyzes a variety of phosphomonoesters at acid pH in vitro. It also shows phosphatase activity towards the protein osteopontin, and the mannose 6-phosphate modification on lysosomal proteins. | * [[Phosphatase_Subfamily_ACP5|ACP5]]. ACP5 subfamily is found in most eukaryotes. Human ACP5 hydrolyzes a variety of phosphomonoesters at acid pH in vitro. It also shows phosphatase activity towards the protein osteopontin, and the mannose 6-phosphate modification on lysosomal proteins. | ||
* [[Phosphatase_Subfamily_PAPL|PAPL]]. PAPL is found in holozoa, but is lost in most arthropods. Its function is unclear. | * [[Phosphatase_Subfamily_PAPL|PAPL]]. PAPL is found in holozoa, but is lost in most arthropods. Its function is unclear. | ||
Revision as of 22:43, 26 May 2015
Phosphatase Classification: Fold MTDP: Superfamily MTDP: Family PAP (purple acid phosphatase)
PAP is short for purple acid phosphatase. The family is found in most eukaryotes, even in some prokaryotes. It has two subfamilies present in human:
- ACP5. ACP5 subfamily is found in most eukaryotes. Human ACP5 hydrolyzes a variety of phosphomonoesters at acid pH in vitro. It also shows phosphatase activity towards the protein osteopontin, and the mannose 6-phosphate modification on lysosomal proteins.
- PAPL. PAPL is found in holozoa, but is lost in most arthropods. Its function is unclear.
