Difference between revisions of "Phosphatase Glossary"

Revision as of 01:58, 4 January 2015

Cell signaling

Fructose-2,6-bisphosphatase

A signal molecule that controls glycolysis and overall intracellular reactive oxygen species (ROS) levels. Also see wikipedia page.

Taxonomic Terms

Holozoa

• Metazoan
• + unicellular Choanoflagellates (sequenced genomes include Monosiga brevicollis and Salpingoeca rosetta)
• + the more basal clades Filasteria (e.g. Capsaspora owczarzaki and Ministeria vibrans)
• + Ichthyosporea (fish parasites including Amoebidium parasiticum)

These unicellular holozoa (sometimes called Choanozoa, though this is most likely to be paraphyletic) have a large number of kinases and other genes that were previously thought to be animal-specific and so are of strong interest to understand the origins of animals. The closest major out-group of the holozoa are the fungi.

Metazoa

Metazoans are the same as animals, a group of multi-cellular eukaryotes. They are a subset of the holozoan, which includes a few unicellular groups such as choanoflagellates. Within the Metazoa, the earliest branching lineages are sponges (they may be monophyletic or polyphyletic), which have little tissue structure. Eumetazoan ("true metazoans") consist of all metazoans other than sponges.

Eumetazoa

Opisthokont

Ecdysozoa

Bioinformatics

SCOP

Structural Classification of Proteins is a database of protein structural relationships. There are two versions: SCOPe at Berkeley and SCOP2 at MRC, Cambridge, UK.

Pfam

The Pfam database is a large collection of protein domain families. Each family is represented by multiple sequence alignments and hidden Markov models (HMMs). Link.