Phosphatase Glossary
Cell signaling
Fructose-2,6-bisphosphatase
A signal molecule that controls glycolysis and overall intracellular reactive oxygen species (ROS) levels. Also see wikipedia page.
Taxonomic Terms
Holozoa
- Metazoan
- + unicellular Choanoflagellates (sequenced genomes include Monosiga brevicollis and Salpingoeca rosetta)
- + the more basal clades Filasteria (e.g. Capsaspora owczarzaki and Ministeria vibrans)
- + Ichthyosporea (fish parasites including Amoebidium parasiticum)
These unicellular holozoa (sometimes called Choanozoa, though this is most likely to be paraphyletic) have a large number of kinases and other genes that were previously thought to be animal-specific and so are of strong interest to understand the origins of animals. The closest major out-group of the holozoa are the fungi.
Metazoa
Eumetazoa
Opisthokont
Ecdysozoa
Bioinformatics
SCOP
Structural Classification of Proteins is a database of protein structural relationships. There are two versions: SCOPe at Berkeley and SCOP2 at MRC, Cambridge, UK.
Pfam
The Pfam database is a large collection of protein domain families. Each family is represented by multiple sequence alignments and hidden Markov models (HMMs). Link.
