Difference between revisions of "Phosphatase Subfamily DCR2"

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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_MTDP|Fold MTDP]]:[[Phosphatase_Superfamily_MTDP|Superfamily MTDP]]: [[Phosphatase_Family_PAP|Family PAP]]: [[Phosphatase_Subfamily_DCR2|DCR2]]
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_PPPL|Fold PPPL]]: [[Phosphatase_Superfamily_PPPL|Superfamily PPPL]]: [[Phosphatase_Family_PAP|Family PAP]]: [[Phosphatase_Subfamily_DCR2|DCR2]]
  
 
=== Evolution ===
 
=== Evolution ===

Latest revision as of 17:25, 13 March 2017

Phosphatase Classification: Fold PPPL: Superfamily PPPL: Family PAP: DCR2

Evolution

The DCR2 subfamily is found in most fungi, most plants and a few chromalveolates.

Domain Structure

DCR2 has a single phosphatase domain.

Function

DCR2 dephosphorylates Ire1, a conserved endoplasmic reticulum transmembrane UPR sensor in Saccharomyces cerevisiae [1].

References

  1. Guo J and Polymenis M. Dcr2 targets Ire1 and downregulates the unfolded protein response in Saccharomyces cerevisiae. EMBO Rep. 2006 Nov;7(11):1124-7. DOI:10.1038/sj.embor.7400813 | PubMed ID:16990850 | HubMed [Guo06]