Difference between revisions of "Phosphatase Superfamily PPPL"

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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_MTDP|Fold MTDP]]: [[Phosphatase_Superfamily_MTDP|Superfamily MTDP]]
 
[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_MTDP|Fold MTDP]]: [[Phosphatase_Superfamily_MTDP|Superfamily MTDP]]
  
MTDP is short for MeTallo-Dependent Phosphatases. It has two families:
+
MTDP is short for MeTallo-Dependent Phosphatases. It is named after the [http://scop.berkeley.edu/sunid=56299 fold] and superfamily [http://scop.berkeley.edu/sunid=56300 superfamily] in SCOP database. Members of the superfamily can be detected by corresponding HMMs of [http://pfam.xfam.org/family/PF00149 Pfam] and [http://supfam.cs.bris.ac.uk/SUPERFAMILY/cgi-bin/scop.cgi?sunid=56300 SUPERFAMILY]. The superfamilies consists of [http://scop.berkeley.edu/sunid=56300 multiple families as shown in SCOP database]. Not all of the families are protein phosphatases or even phosphatases. Here, we focus on two families that dephosphorylate proteins:
  
 
* [[Phosphatase_Family_PPP|PPP]] - Serine/threonine-specific phosphatase.
 
* [[Phosphatase_Family_PPP|PPP]] - Serine/threonine-specific phosphatase.
 
* [[Phosphatase_Family_PAP|PAP]] (purple acid phosphatase) - phosphatase of a wide variety of substrates, including protein.
 
* [[Phosphatase_Family_PAP|PAP]] (purple acid phosphatase) - phosphatase of a wide variety of substrates, including protein.

Revision as of 17:03, 5 January 2015

Phosphatase Classification: Fold MTDP: Superfamily MTDP

MTDP is short for MeTallo-Dependent Phosphatases. It is named after the fold and superfamily superfamily in SCOP database. Members of the superfamily can be detected by corresponding HMMs of Pfam and SUPERFAMILY. The superfamilies consists of multiple families as shown in SCOP database. Not all of the families are protein phosphatases or even phosphatases. Here, we focus on two families that dephosphorylate proteins:

  • PPP - Serine/threonine-specific phosphatase.
  • PAP (purple acid phosphatase) - phosphatase of a wide variety of substrates, including protein.