Gene TIM50 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily TIM50
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP164_AA protein Get Run
AqueP164_AA_150-256 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_TIM50_pd Subfamily TIM50 134-259 1.7e-58 188.2 In-house 1-126 (126) alignment 
Range on Protein: 134-259
Range on HMM: 1-126/126.0
TLLIEVKDIFIHSDYERNMGWRHQKRPGLDAFLNALFDYYEIVVFTSENALSTHPIIDKMDPNQYIMYRLYRDSTKYISGEHVKDLTHINRSLNRVIMVD
||..|.||...|.......|||..||||.||||..|....||||||||..|...|.|||.||.|.|||||.||.|||..|||||||...||.|..||.||
tlvlelkdvlvhpewtyktGwrfkkrPgvdafleqlaelfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvd

TNPLSVKLQPENSIILDKWTGDIYDT
... ||||||||...|.||.|. .|.
ldkksvklqpenalalkkweGnaddk
NIF NLI interacting factor-like phosphatase 137-280 1.1e-34 111.6 Pfam-A 5-159 (159) alignment 
Range on Protein: 137-280
Range on HMM: 5-159/159.0
IEVKDIFIHSDY-----------ERNMGWRHQKRPGLDAFLNALFDYYEIVVFTSENALSTHPIIDKMDP-NQYIMYRLYRDSTKYISGEHVKDLTHINR
... .. .||             |... .. .|||||| ||. |  .||.|.||...    .|..||.|| .... .||||.|...  |..||||. ..|
LDLDetLvhskekkdlkedgkkveektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklfkkrlyresctlrngkyvKdLsllgr

SLNRVIMVDTNPLSVKLQPENSIILDKWTGD-IYDTSLKDLGAFLLTIAmSNtDDVR
.|.||..|| .| |..|||.| | .... ||   ||.|..|  ||  ..  . ||||
dlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpfleale.ks.ddvr
subfamily_FCP1_pd Subfamily FCP1 140-232 1.3e-06 20.5 In-house 29-123 (146) alignment 
Range on Protein: 140-232
Range on HMM: 29-123/146.0
KDIFIHSDYERNMGWRHQKRPGLDAFLNALFDYYEIVVFTSENALSTHPIIDKMDPNQYIMY-RL-YRDsTKYISGEHVKDLTHI-NRSLNRVIMV
|||   .  |... .  ..||.| .||. | ..||. ..| ..   .. |   .||.. .   |.  ||     . ...|.|... ..  . |...
kdikkftlpeekevyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrd.elldassktkklkklfptddsmvvii
CPDc_SM00577 151-256 4.9e-28 89.9 In-house 36-143 (146) alignment 
Range on Protein: 151-256
Range on HMM: 36-143/146.0
NMGWRHQKRPGLDAFLNALFDYYEIVVFTSENALSTHPIIDKMDPNQYIMYR-LYRDSTKYISGEHVKD-LTHINRSLNRVIMVDTNPLSVKLQPENSII
.. ..  |||..| ||. . ...|.|.|||...   ..|.| .||.....|| |||..... .|...|| |. ....|..|...|... |....||| . 
etlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkrllkyrvlyRqdcrlvkgkllkddlsllkvdlskvviiDnseestlvnpenalk

LDKWTGDI
  ..  . 
ikpyisal
subfamily_DULLARD_pd Subfamily DULLARD 154-259 1.5e-22 72.0 In-house 46-152 (153) alignment 
Range on Protein: 154-259
Range on HMM: 46-152/153.0
WRHQKRPGLDAFLNALFDYYEIVVFTSENALSTHPIIDKMDPNQ-YIMYRLYRDSTKYISGEHVKDLTHINRSLNRVIMVDTNPLSVKLQPENSIILDKW
..  ||| .| ||.    .|..|.||.     .....||.| ..  .  |.||..    ||...|||. .. .|..||..|  | . . .|.|.| .. |
fyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqhCvlesgkytkdlslvssdlssviilDnspvayrknpdnaipiksw

TGDIYDT
  |  ||
lsdpsdt
subfamily_SCP_pd Subfamily SCP 157-259 4.3e-24 76.9 In-house 40-142 (142) alignment 
Range on Protein: 157-259
Range on HMM: 40-142/142.0
QKRPGLDAFLNALFDYYEIVVFTSENALSTHPIIDKMDPNQYIMYRLYRDSTKYISGEHVKDLTHINRSLNRVIMVDTNPLSVKLQPENSIILDKWTGDI
.||| .| ||... . .|.|.||.  |  ..|. | .| .. . .||.|.|  .  | .||||... |.|..||.||  | |  . |||.. .. |  | 
lkrphvdeflkrvgelfevvlftaslakyadpvadlldkkkvlrarlfrescvfhkgnyvkdlsrlgrdlkkviivdnspasyifhpenavpveswfddk

YDT
 ||
edt
subfamily_CTDSPL2_pd Subfamily CTDSPL2 157-258 1.9e-22 71.8 In-house 39-141 (142) alignment 
Range on Protein: 157-258
Range on HMM: 39-141/142.0
QKRPGLDAFLNALFDYYEIVVFTSENALSTHPIIDKMDPNQY-IMYRLYRDSTKYISGEHVKDLTHINRSLNRVIMVDTNPLSVKLQPENSIILDKWTGD
..|| |  ||. . . .|...||. . . .. ..| .||..  | .||.|..  ...|...|||. . | |...|.|| .|..  .| || | .. |  |
rlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlfrehcvcvdgnyikdlsilGrdlektiivdnspqafayqlenGipieswfed

IYD
  |
end