Gene ACP5-2 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily ACP5
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP173_AA protein Get Run
AqueP173_AA_0-214 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
ACP5 1-214 8.8e-68 219.9 In-house 3-197 (198) alignment 
Range on Protein: 1-214
Range on HMM: 3-197/198.0
MIGDWGGMPSPPYYTdaehvLAGVMGDKAQEISSDFTVAMGDNFYTYGVKSVDDPRFKETFEDVFTADSLQKRWYVFCGNHDHYGNASAQVAYTQKSSRW
..||||....... .      |  ||. |.. . || ...|||||. ||.|||||||||.||...||.|||. ||| .||||..||.|||..|...| ..
vvGDwGrkgeynqsa.....vakqmgkvaekldidfvlslGDnfyddGvtsvddprfkesfekiytakslqvpWyvvlGNHDyrgnvsaqieyakrskds

YMPDLYYTETFKLNDSNGTTVQmvfidtvllagvthPELRSLPPSGPEIPNLADDQWAWIESTLKQSTADWLIVSGHYPVWSVAEHGPTDELVKNLRPLL
 .| |.|. ..|  . .  | .              .. .|  ....|  . | .|..|.|..|..|||||.|| ||.||.|..|||.|.|||..|.|||
rfpslryslskkevvtelftek..............kdeksdqrevaerekyaeeqlkwlekalakstadwkiVvGHhpvySigehgdtkelverllpll

IKYNVTAYFCGHDH
 ||.|.||..||||
kkykvdaYlnGHdH
subfamily_PAPL_pd Subfamily PAPL 2-215 2e-101 329.6 In-house 3-211 (212) alignment 
Range on Protein: 2-215
Range on HMM: 3-211/212.0
IGDWGGMPSPPYYTDAEHVLAGVMGDKAQEISSDFTVAMGDNFYTYGVKSVDDPRFKETFEDVFTADSLQKRWYVFCGNHDHYGNASAQVAYTQKSSRWY
.|||||... ||.|.|.. .| ..|..|.|....|..|.|||||. |||.|||.||||||||||||.|||..|||..||||..||.|||.||...|.||.
lgDwGgleeapyttaaqeavakelgkvaeeleaqfvlalGDnfYekGvkdvddarfketfedvftaeslqvpwyvvagnHDykGnvsaqiaYsklskrWk

MPDLYYTETFKLNDSnGTTVQMVFIDTVLLAGVTHPeLRslpPSGPEIPNLADDQWAWIESTLKQSTADWLIVSGHYPVWSVAEHGPTDELVKNLRPLLI
.|.||||..||..||  .|||.|.||||||.|.... |.   ..||.  .||..||||.|..||.|.||.|||.||||||||||||||..|||.|.|||.
fpslyytksfkipds.natvqlvlidtvllcgksdd.lk...legpvdvslaeeqwawleeeLkaseadylivaGhypvwsvaehGptkiLvkrLkPlLe

KYNVTAYFCGHDHD
|||||||..||||.
kynvtaylsGhDhn
Metallophos Calcineurin-like phosphoesterase 2-214 7.3e-16 52.0 Pfam-A 6-198 (200) alignment 
Range on Protein: 2-214
Range on HMM: 6-198/200.0
IGDWGGMPSPPYytdaeHvLAGVMGDKAQEISSDFTVAMGDNFYTYGVKSVDDPRFKetfeDVFTADSLQKRWYVFCGNHDHYGNASAQVAYTQKSSRWY
|||..|..  ..       |.  . ..|.|   |. . .||...     |    ..           .| .....  |||. .. .||  ..  ......
igDlHgglddle.....d.lllillkiaaeekpdlvlflGDlvdrgdwssetlalld....ylvlklllpipvfllrGNHesdpgnsaygflleqlkdlr

MPDLYYTETFKLndsngttvqmvfiDtVLLAGVTHPELRSLPPSGPEIPNLADDQWAWIESTLKQSTADWLIVSGHYPVWSVAEHGPT----DELVKNLR
 .. .. |.. |             . . |   . .   .. . .   .. .. |. . .  .. . .|. |. .| |..|  ..| .    .   ..|.
glangeeeyenl.............k.itllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddigselfgpdale

PLLIKYNVTAYFCGHDH
.|| ||.|.....||.|
kllekygvdlvlrGHtH
subfamily_ACP5_pd Subfamily ACP5 29-215 5.4e-15 47.8 In-house 20-187 (189) alignment 
Range on Protein: 29-215
Range on HMM: 20-187/189.0
AQEISSDFTVAMGDNFYTYGVksvDDPRFKETFEDVFTADSLQKRWYVFCGNHDHYGnasaqvA---YtqkSSRWYMPdlyytETFKLNDSNGTTVQMVF
... . |... .||  |  .    .. .  ..| ...   . .  . |. |||..            |   ..|. ||     .  .    . . |... 
eeaneldliihvGDlaYalka...kneavwdefmnlieplaskvPymvsiGnhesds......nfsay...kkrfsmp.....sknewYsfdygpvhfis

IDTVLLAGVThpelrslppsgpeipnlaDDQWAWIESTLKQS----TADWLIVSGHYPVWSVAEHGP----TDELV-----KNLRPLLIKYNVTAYFCGH
..|     .                   ..|..|.|. ||.     . .|.|| || |..   ...     .. ||     ..| .|| ||.|  ...||
lstevdfslg..................seqykWLekdLkeannrkktpwiivmgHrPmYcsnkdeddctkeetlvrkglresledllykykvdlalsgH

DHD
.| 
eHs
Metallophos_2 Calcineurin-like phosphoesterase superfamily domain 29-224 2.5e-06 19.6 Pfam-A 23-129 (156) alignment 
Range on Protein: 29-224
Range on HMM: 23-129/156.0
AQEisSDFTVAMGDnfytygvkSVDDprfKETFEDVFTAdslqkRWYVFCGNHDhygnasaqvA----------Ytqkssrwympdlyytetfklndsng
..|   |. .  ||        .|.    .|..|.. ..     . .. .||||         .          .                         
ike..vdlilhaGD........lvep...eevvelledi.....pvlavrGnhD.........eaelpkelavel.........................

ttvqmvfidtvllagvthpelrslppsgpeipnladdqwawIESTLKQSTADWLIVSGHYPVWSVAehgptDELVkNLRPLLIKYNVTAYFCGHDHDIQH
                                         ..  .. .  .. ..  |   .||      ..   .|. || .... ..|.|| |  . 
.........................................llaaaaleiegdrvllvhgtplsvq.....ssee.elaellkeagadlvflGHtHkpkv

IKEDGS
 |..| 
ekrggt
PAPL 155-214 1.2e-10 33.8 In-house 126-192 (194) alignment 
Range on Protein: 155-214
Range on HMM: 126-192/194.0
DQWAWIESTLKQ---STADWLIVSGHYPVWSVAEHG----PTDELVKNLRPLLIKYNVTAYFCGHDH
.|..| |  |..   |  .|.|| || |...  ..      ... ...| .||.||.|  ...|| |
eqyewleedlakvnRsktPWiivmgHrpmYcsnkdkddckekakmlaaledllykygVDlvlaGHeH