Gene ACP2-1 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP2
Subfamily ACP2
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP193_AA protein Get Run
AqueP193_AA_18-371 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0048946 Phosphoglycerate mutase-like 19-371 1.6e-80 264.1 In-house 33-415 (447) alignment 
Range on Protein: 19-371
Range on HMM: 33-415/447.0
SAVLSEEELQFVSVVIRHGARSPV-----------------------------ESYPADRYQEDFWPQGFGQLSIKGMREEYHLGTVFKSRYldTGFMDs
..| .. ||..| |..|||||.|.                               .... ..| .|| |.|||. .|... |.||  ...||  .|... 
epvpegcelkqvqvlfRHGaRtPtkkylkgleplldllknanvlelggdlsflndwkyqlkneplwpcglgqLTplGreqlyelGkrlrkrY..lgllp.

gyNRSQIYVRSTDYDRTLMSAQCVLAGMYPPGenqmfdPDLEWQPIPVHTTPQKYDSLLNVaSCPVYDKLMDKDNNtyKQIQDANQELFDNLTEWTGE-D
  |.|.|||||.|.||||.|||..|||..||       |.|..||||.||.|  .| ||.  ||| ...|. |  .  . ... ..||.. | . .|  .
..npseiyvrssdvdRtlqSaqaflaGlfppe......pplgyqpipihtvpssndnlllp.sCpafkellkkela..eelkellkellerlkkllggln

INVITVGLLKDALFVEYHDNNLT-MPEWFSPQLLTKLESIDDSLLRLMFS-TKCKRKLTGGVWTNRVLKDMQNKATGvmPDmKMVLYSAHDTTVATMLSV
...  |  | |.|..|.  ..|.  ...|.|..|..|| . |   ..... .   ..|.||.. | .|....... |     |..||.|||||.|..||.
ltlsdvydlydlllyetaihglsplcslftpeelevleyladlefyyeygygdelarlaggpllneilarledaisg..ds.klylyfaHdttiaallsa

FDMFDGKQP------------------PYSAAFAVELYSSGSS---KNDFFVRFYYHNEtdsndfvELTHPNCSKD----CPLEKLKQIMAPYrLTekEW
.. || ..|                  ||.. ...|||.  ||   .....||..| .|       .|. |.|. .    |||...|... .. |   .|
LglfddelplpadnlpfnrlfrsseivPyasnlvfElyecpsslpsdgeyyVrvlynge.......plplpgCgsgpgglCplddFkellkkf.lp..dw

SSSCSTTTAP
 . |  |.  
eklCgltlsv
0047369 Phosphoglycerate mutase-like 19-365 8.8e-78 255.3 In-house 36-436 (438) alignment 
Range on Protein: 19-365
Range on HMM: 36-436/438.0
SAVLSEEELQFVSVVIRHGARSP-----------------VESYPADRYQEDF---WPQGFGQLSIKGMREEYHLGTVFKSRYldtGFMdsgyNRSQI-Y
 .| .. ||..| |..|||||.|                 .  || . ..      .|.|.|||. .|... |.||  . .||   |..    |.... |
ldvpegcelkqvqvlfRHGaRtPtksklkkleplwellenattypsgplsflndwlgpcgagqLTplGreqayelGkrlrkrY...glL....npedvly

VRSTDYDRTLMSAQCVLAGMYPPGENQMFDPDLeWQPIPVHTTPQKYDSLL---NVASCPVYDKLMDKDNNT-------YKQIQDANQELFDNlTEWTGE
|||.|.||||.|||..|||..||  .... |.| |||||.|| | ..|.||   .  ||| .|.|.... ..       .|.|..  ..|... ...| .
vrssdvdRtlqSAqaflaGlfppegtgelapil.wqpipihtipesddfllnllpsdscpafdellkeflasdeflelllkdilkrlkkllpg.lnltps

DINVITVGLLKDALFVEY-HDNNLTMPEWFSPQLLTKLESIDDSLLRLMF-STKCKRKLTGGVWTNRVLKDMQNKATGvMP----------------DMK
|.. . . .  | |. .| . ... ....|.|..|..|| . |     .. ...  .||.||.. | .|........|                   | |
dvldlydlcaydtlangyaglplspfcslftpeelevleyladlefyylygygnelaklaggpllneilarledaing.kstnlnltldsngvtfPldlk

MVLYSAHDTTVATMLSVFDMFDGKQP---------------------PYSAAFAVELYSSGsSKNDFFVRFYYhnetdsNDfVELTHPNCSKD----CPL
..||.|||||.|..||....|| ..|                     ||.. ...|||. . |.....||..|      |. ..|. |.|. .    |||
lylyfaHdttiaallsaLglfddtwplpglpldkialnrlfrsseivPyasnlvfElyecp.sdgeyyVrvly......ng.kvlplpgcgsgpgglCpl

EKLKQIMAPYRLTekEWSSSC
...|... ... .   . . |
ddFkelvkkllpg..dfeelC
0049059 Phosphoglycerate mutase-like 20-365 1.7e-78 257.5 In-house 36-434 (435) alignment 
Range on Protein: 20-365
Range on HMM: 36-434/435.0
AVLSEEELQFVSVVIRHGARSPVESY-----------------PAD---RYQEDFWPQGFGQLSIKGMREEYHLGTVFKSRYldtGFMdsgYNRSQIYVR
.| .. ||..| |..|||||.|....                 | .   .. . ..|.|.|.|. .|... |.||  . .||   ||.   ||....|||
dvpegcelkqvqvlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrY...gfL...ynpdevyvr

STDYDRTLMSAQCVLAGMYPPG--ENQMFDPDLEWQPIPVHTTPQKYDSLlNVASCPVYDKLMDKDNNT-------YKQIQDANQELFDNlTEWTGEDIN
|.|.||||.|||..|||..||   . |...|. ..||.|..| .. .|.| .  ||| .|.|.... ..       ...|..  |||... ...| .|..
ssdvdRtlqSaqaflaGlfppeilgsqllnplnvyqpvpietvdsdndtl.pydscpafdellkellasdeflelflerilkllqellpg.lgltpsdvl

VITVGLLKDALFVEYhDNNLTMP--EWFSPQLLTKLESIDDSLLRLMFS-TKCKRKLTGGVWTNRVLKDMQNKATG---------------VMPDMKMVL
 .    . | |...|  ..|..|  ..|....| .|| . |    .... .   .||.||.. | .|....... |               .. | |..|
dlydlckydtlllgy.ahglplpfcslfteeelevleyladlefyylygygdeiaklaggpllneilarledaingdstnlnltldsnpatfpldlklyl

YSAHDTTVATMLSVFDMFDGKQP---------------------PYSAAFAVELYSSgSSKNDFFVRFYYhNEtdsndfVELTHPNCSKD----CPLEKL
|.|||||.|..||....||...|                     ||.. ...|||.  ...|...||..| |.      ..|. |.|. .    |||...
yfaHdttiapllsaLglfddqlplpadntpfpeldrlfrtseivPyasnlvfElyec.pdgneyyVrvly.ng......kvlplpgcgsgpgglCplddF

KQIMAPYrLTEKEWSSsC
|... .. | . ...  |
kelvkkf.lpgddfde.C
0048439 Phosphoglycerate mutase-like 22-354 1.7e-76 251.0 In-house 4-389 (391) alignment 
Range on Protein: 22-354
Range on HMM: 4-389/391.0
LSEEELQFVSVVIRHGARSPVESYPA--DRYQEDFW---PQGFGQLSIKGMREEYHLGTVFKSRYLDTGFMDSGY--NRSQIYVRSTDYDRTLMSAQCVL
 .. ||..| |..|||||.|. |||   | . . ..   | |.|.|. .|... |.||  . .|| |.|...|.|  |.|..||||.|.||||.|||..|
pagcelkqvqvlfRHGaRtPtssypnkldpllnkllpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevyvrssdvdRtlqSAqafl

AGMYPPGENQMFDP------DLEWQPIPVHTTPQKYDSLLNVA-SCPVY-------DKLMDKDN--NTYKQIQDANQ---ELFDNLTEWTGED----INV
||..||....   .      |. ..|.|..| |   |.||  | |....       ..|..  |    .... . ..   .|....| ..|       ..
aGlfpplgltvilvivvesedpllnplpintcplledlllldalsalprfylseilerlaevlnrvlglnltaedvlslfdlcaketaalgsllklsspl

ITVGLLKDALFVEYHdNNLTMPEWF-----SPQLLTKLESIDDSLLRLMFSTKCKRKLTGGVWTNRVLKDMqnkATG-VmPDMKMVLYSAHDTTVATMLS
  .  | |.|..||  ..|..|||.     ||.||..| .. . |. ......  .||.||.. | .|.|.   ..    .| |..||.|||||.|..||
cdlftlydtllyeya.hglplpewltdellspellkqladlvnelyyyltgsgeiaklaggpllneilddl...vangp.sdpklylyfaHdttiaalls

VFDMFDG------KQPPYSAAFAVELYSSgSSKNDFFVRFYYHNETDSN-------------DFVELTHPNCSKD----CPLEKLKQIMAPY
....|.       ..|||.. ...|||.  .|.....||..|...| .               .. |. |.|. .    |||....... ..
aLglfndtlplpadlppyasnlvfElyec.psdgeyyVrvlynggtldlprdltlldldefllrlvlplpgcgsgpgglCplddFvelvkkr
subfamily_ACP2_pd Subfamily ACP2 23-369 9e-118 385.9 In-house 5-360 (361) alignment 
Range on Protein: 23-369
Range on HMM: 5-360/361.0
SEEELQFVSVVIRHGARSPVESYPADRYQEDFWPQGFGQLSIKGMREEYHLGTVFKSRY-LDTGFMDSGYNRSQIYVRSTDYDRTLMSAQCVLAGMYPPG
.| .|.||.|..|||.|||...|| | |.|| ||||.|||. .||...|.||.....||  ||.|.|. ||..||||||.|..|||||||.||||..||.
eerkLkfvqvlfRHGdRsPlntypndkykedewpqglGqLTeeGmqqqyeLGkfLrkrYvedtkfldakynpkqiyvrSsdvnRTlmSaqsvlaglfppe

ENQMFDPDLEWQPIPVHTTPQKYDSLLNV-ASCPVYDKLMDKDNNT--YKQIQDANQELFDNLTEWTGEDINVITVGLLKDALFVEYHDNN-LTMPEWFS
... .... ||||.||||.....| ||.  ..||.||.|... ...  .|.. . |.||...|.| |||||.  ..  |.|.|..| . .| |..|||..
tgvdypdeqeWqpvPvhtvseeedlllrakknCprydellqeakespevkklleenkelleklsestgedidlenfyqlsdtlicerkyanelnlpewan

PQLLTKLESIDDSLLRLMFS-----TKCKRKLTGGVWTNRVLKDMQNKATGVMPD--MKMVLYSAHDTTVATMLSVFDMFDGKQPPYSAAFAVELYSSgs
 .|..|||.. |.  ...|.     |. ..||.||.. |..|..|..|...   .  .|..||||||||.|..|.....|..|.|||..|..||||..  
delfekleeladkvkeaefglnnektrelkklrgGpllnellenmkeklkceekkkklklflYSaHDttlaalLeaLgifekkappyasaiivElyee..

SKNDFFVRFYYHNETDSNDFvELTHPNC--SKDCPLEKLKQIMAPYRLTEkeWSSSCSTTT
......|...|.|||... . |||.|.|  ..||||.|.|.|. |.....  ... | ..|
ddgkplvkvlyrnetskdpp.eltlpgCkgeedCplskfkkivkpfipdd..vdelCeakt
0049226 Phosphoglycerate mutase-like 25-365 1.9e-85 280.0 In-house 1-340 (342) alignment 
Range on Protein: 25-365
Range on HMM: 1-340/342.0
EELQFVSVVIRHGARSPVESYPADRYQEDFWPQGFGQLSIKGMREEYHLGTVFKSRYldTGFMDSGYNRSQIYVRSTDYDRTLMSAQCVLAGMYPPGENQ
|.|..| |.||||.|.|. ..| | ..| ||. |.|.|. .|....|.||  ...||  .|...| ||....||||.|.||||.|||..|||..||   .
ekLkqvqvliRHGdRtPlakgpldflnewfwgcglgeLTplGreqayelGrrlrkrY..lgllpstynpdevyvrssdvdRtlqSaqaflaGlfppeltp

MFDPDLEWQPIPVHTTPQKYDSLL--NVASCPVYDKLMDKDN--NTYKQIQDANQELFDNLTEWTGEDI-NVITVGL-LKDALFVEYHDnNLTMPEWF--
 . |.|.|||||..|.| ..|.||  .  ||| .|||...    ...... .  ..|...|....| .. .   |   | | | .|.   .|..|.|.  
ilvplldwqpipiitepesndtllllpydscpnfdkllkellkseevqlfleeildllkklskllglnlstlsdvadtlydlllyelah.glplppwcsl

-SPQLLTKLESIDDSLLRLMFSTKCKRKLTGGVWTNRVLKDMQNKATGvMPDMKMVLYSAHDTTVATMLSVFDMFDGKQPPYSAAFAVELYSSGsskNDF
 ... | .| ..|   . .....   ..|.||.. | .|......  |  .| |..||.|||||.|..||....||...|||......|||. .   ...
ftleelkalyaldllyyygigygeeiarlaggpllneilarleeaieg.psdlklylyfahdttiaallsalglfddqlPpyasnlvfElyecd...gey

FVRFYYHNETDsNDFVELTHPNCSKDCPLEKLKQIMAPYRLTekEWSSSC
.||..|....  . .|.|. |.|.  |||...|....... .  .. . |
yVrvlynggvl.slpvtlplpgcdglcpldefkelvkkflpg..dfeelC
0053031 Phosphoglycerate mutase-like 25-365 6.3e-83 271.8 In-house 1-340 (342) alignment 
Range on Protein: 25-365
Range on HMM: 1-340/342.0
EELQFVSVVIRHGARSPVESYPADRYQEDFWPQGFGQLSIKGMREEYHLGTVFKSRYldTGFMDSGYNRSQIYVRSTDYDRTLMSAQCVLAGMYPPGENQ
|||..| |..|||||.|. ..| |...| |.| |.|.|. .|... |.||  ...||  .|...| ||....||||.|.||||.|||..|||..||   .
eeLkqvivlvRHGaRtPlskgpldplnewfypcgageLTplGreqayelGrrlrkrY..lgllpstynpdevyvrssdvdRtlqSAqaflaGlfppegtp

MFDPDLEWQPIPVHTTPQKYDSLL--NVASCPVYDKLMDK--DNNTYKQIQDANQELFDNLTEWTGedINVIT----VGLLKDALFVEYHDnNLTMPEWF
 . |.|.|||||.|| |  .| ||  |  .|| .|||...   ....|.. .  .||.. |....|  ... .    |  | |.|..|.   .|..|.|.
ilnpllgwqpipihtepessdalllpnydpcpafdkllkealaseevkellerylellqklskglg..ltlsdlldlvsdlydlllyelah.glplppwc

SPQLLTKLESIDDSLLR---LMFSTKCKRKLTGGVWTNRVLKDMQNKATGvMPDMKMVLYSAHDTTVATMLSVFDMFDGKQPPYSAAFAVELYSSGsskN
.  .| .|. . .  |.    ....   .||.||.. | .|.....|  |  .| |..||.|||||.|..||....||.. |||.. ...|||...   .
tlftleelkalyaldllyyyglgpgnelaklaggpllneilarleekisg.pldlklylyfahdttiaallsaLglfddqlPpyasnlvfElyedp...g

DFFVRFYYHNETDSnDFVELTHPNCSKDCPLEKLKQIMAPYRLTekEWSSSC
...||..|...|.| ....|. |.|.  |||...|... .....  .. . |
eyyVrvlynggtls.eplvlplpgcdglcplsefkelvkkllpg..dfeklC
0046349 Phosphoglycerate mutase-like 26-367 7.4e-82 268.6 In-house 6-392 (409) alignment 
Range on Protein: 26-367
Range on HMM: 6-392/409.0
ELQFVSVVIRHGARSPVES---YPADRY-QEDFWPQGFGQLSIKGMREEYHLGTVFKSRYLDTGFMDSG--YNRSQIYVRSTDYDRTLMSAQCVLAGMYP
||..| |..|||||.|. .   .| . .    ..| |.|||. .|... |.||  ...|| |.|...|.  ||...|||||.|.||||.|||..|||..|
eLkqvqvlfRHGaRtPtkklsflpnwpginwtngpcgagqLTplGreqayelGkrlrkrYvdlgLlpsnslynpdeiyvrssdvdRtlqSAqaflaGlfp

PGENQMF------DPDLEWQPIPVHTTPQK-----YDSLLNVAS-CPVYDKLMDKDNNTYKQIQD--------------ANQELFDNLTEWT-----GED
| . . .       .|. .||||..|.|.       | ||.. | || .|||...  ........              ....|.. |.| .     | .
plggeivpllrqdlldppfqpipidtvpiseddalddtllppdslcpaldkllkenlkslsevleflvdealldlelldetkdllkklaerlnselpgln

IN-VITVGL-LKDALFVEYhDNNLTMPEW---FSPQLLTKLESIDDSLLRLMFSTKCKRKLTGGVWTNRVLKDMQNKATG-----VMPDMKMVLYSAHDT
.. .  | . | |.|..|.  ..|..|.|   |.|..| .|. . |    ......  .||.||.. | .|........|     ...| |..||.||||
ltdpldvasllydtllyet.ahglplppwcdlftpeelkvlayladleyyylygsgelaklaggpllneilarledaisgknpvtfpldlklylyfaHdt

TVATMLSVFDMFD-----GKQPPYSAAFAVELYSSgSSKNDFFVRFYYHNEtdsndfvELTHPNCSKDCPLEKLKQIMAPYRLTEK--EWSSSCST
|.|..||... ||      . |||.. ...|||.  .|.....||..|...       .|. |.|.. |||...|... ...   .   . . |. 
tiaallsaLglfdrlfrssdippyasnlvfElyec.psdgeyyVrvlyngg.......plplpgcgegcplsefkellkkrlpgcgltdfdklCpl
His_Phos_2 Histidine phosphatase superfamily (branch 2) 26-322 1.8e-47 154.9 Pfam-A 1-347 (347) alignment 
Range on Protein: 26-322
Range on HMM: 1-347/347.0
ELQFVSVVIRHGARSPVESYPADRY--------------------Q------EDFWPQGFGQLSIKGMREEYHLGTVFKSRYLdtGFMDSGYNRSQIYVR
||..| ||||||.|.|.......                             .  .. . |.|  .|..... ||  ...||   |.... ........|
eLkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYp..gllrdhltyedvkir

STDYDRTLMSAQCVLAGMYPPGE---NQMFDPDLEWQPIPVHTTPQ---KYDSLL--NVASCPVYDK----LMDKDNNTYKQIQDANQELFD-NLTEW-T
|....|.|.|||...||...| .    .  .. | .......| ..   | . ||  . .||| ...    . ..  .  .. .   .| .  .|..  |
ssserRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsalct

GE-DINVITVGLLKDALFVEYH-DNNLTMPEWFSP--QLLTKLESID---DsLLRLMFSTKCKRKLTGGVWTNRVLKDMQNKATGVM--PDMKMVLYSAH
||  ..   .  . .. |.|    .....||...   . . ... ..     | .|.  ..  ..  |. . |..|| ..... .    .. |..||..|
gednllfkerweklfreffeeekfdiskipelydtmkydalhnrqledlee.lyklygigdeeklkigllllnpllkkilsdleetqpsrhaklrlyfth

DTTVATMLSVFDMFD------GKQPPYSAAFAVELYSSgsSKNDFFVRFYYH
|....|.|.......       ...||...  .|||..  |...|.|| ...
DshiytllnaLgleekiareaspelpyasqivfelyed..sekkfyvrllfs
His_Phos_2 Histidine phosphatase superfamily (branch 2) 26-322 1.8e-47 154.9 In-house 1-347 (347) alignment 
Range on Protein: 26-322
Range on HMM: 1-347/347.0
ELQFVSVVIRHGARSPVESYPADRY--------------------Q------EDFWPQGFGQLSIKGMREEYHLGTVFKSRYLdtGFMDSGYNRSQIYVR
||..| ||||||.|.|.......                             .  .. . |.|  .|..... ||  ...||   |.... ........|
eLkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYp..gllrdhltyedvkir

STDYDRTLMSAQCVLAGMYPPGE---NQMFDPDLEWQPIPVHTTPQ---KYDSLL--NVASCPVYDK----LMDKDNNTYKQIQDANQELFD-NLTEW-T
|....|.|.|||...||...| .    .  .. | .......| ..   | . ||  . .||| ...    . ..  .  .. .   .| .  .|..  |
ssserRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsalct

GE-DINVITVGLLKDALFVEYH-DNNLTMPEWFSP--QLLTKLESID---DsLLRLMFSTKCKRKLTGGVWTNRVLKDMQNKATGVM--PDMKMVLYSAH
||  ..   .  . .. |.|    .....||...   . . ... ..     | .|.  ..  ..  |. . |..|| ..... .    .. |..||..|
gednllfkerweklfreffeeekfdiskipelydtmkydalhnrqledlee.lyklygigdeeklkigllllnpllkkilsdleetqpsrhaklrlyfth

DTTVATMLSVFDMFD------GKQPPYSAAFAVELYSSgsSKNDFFVRFYYH
|....|.|.......       ...||...  .|||..  |...|.|| ...
DshiytllnaLgleekiareaspelpyasqivfelyed..sekkfyvrllfs
subfamily_ACP6_pd Subfamily ACP6 59-368 4.5e-43 139.4 In-house 75-374 (376) alignment 
Range on Protein: 59-368
Range on HMM: 75-374/376.0
FGQLSIKGMREEYHLGTVFKSRYLD-TGFMDSGYNRSQIYVRSTDYDRTLMSAQCVLAGMYppgENQMFDPDLewqPIPVHTTPQKYDSL-LNVASCPVY
 |||   ||.. . ||   . ||..  .|.   .|  ..|.|||. .||| ||.|..||.|   .... . .|   || ..|. .. . |  |  .||  
kGqLtkvGmqqvfdLGrkLrkrYvedikfLsqefnpqevyiRstnieRtlesarclvaGLy...gkiiiqkel...piilytdeedeevlyPnrqrcpll

DKLMDKDNNTYKQIqDANQELFDNLTEWTGED--INVITVGlLKDALFVEyHDNNLTMPEwFSPQLLTKLESIDDSLLRLMFSTKCK-----RKLTGGVW
 . . . ...  .. .   |  ... .  . .   ..  |. |.| .  . .. ||..|.    ...  .|    . |..... . .      ||. |  
srayrsvrksaisl.pGisedtkqiadvldiseekkldfvs.lrDniaAr.laHnlkvpp.ilkdvidliekhAveelvvlleggdrpekeilklsvGkv

TNRVLKDMQNKATGVMPDMKMVLYSAHDTTVATMLSVFDMFDGKQPPYSAAFAVELYSSgsSKNDFFVRFYYHNEtdsndfvELTHPNCSKD-CPLEKLK
 . .|. ....  . .|  |. ||||||||. |.|  ...||.| ||..|  ..|||     ....||| .|...       ||  ... .| .|||| |
lkeilenlekakekeiparklrLysaHDttlmtLLlalgvFDdkWPpfaadvileLyed..kageyfvrvlYqek.......elrlrgseedlvPlekFk

QIMAPYRLtEKEWSSSCSTT
...|.. |  |.... |...
allavlvl.pkdyaaeCkle
subfamily_HP2-Group1_pd Subfamily HP2-Group1 59-162 1.6e-17 54.9 In-house 92-195 (422) alignment 
Range on Protein: 59-162
Range on HMM: 92-195/422.0
FGQLSIKGMREEYHLGTVFKSRYLDTGFMDSGYNRSQIYVRSTDYDRTLMSAQCVLAGMYPPGENqMFDPdleWQPIPVHTTPQKYDSLL-NVASCPV--
 .||...| ...   | .... |.||||. | .. |..|.|| |  ||..|||... ||||.      |     | ....|  . .||.  |   ||   
vaqltleGykqqelnGqilrkvyvdtGflkssldssevylrsddesrtilsaqalilGmypqdtk.aedr...aqvvdlytrdklfdsieanadlcpkls

-YDKLMDK
 |.. . |
eyntqflk
subfamily_PXYLP1_pd Subfamily PXYLP1 59-191 5.6e-09 26.7 In-house 103-225 (419) alignment 
Range on Protein: 59-191
Range on HMM: 103-225/419.0
FGQLSIKGMREEYHLGTVFKSRYLDT-GFM--DSGYNRSQIYVRSTDYDRTLMSAQCVLAGmyppgenqmFDPDLEWQPIPVHTTPQKYDSlLNVASCP-
 |||  ||.    ..|....  |. . ...  .  ... .... .| . ||| ||  .| |         . |. ... | |...|.     |.  ||| 
lgqLtqkGvvqhLevGdllrkvYakklklLlkpnelssDevvlettrkrrtlqsalallyg.........llpkaklkairvrespsvafC.lgeCsCPa

VYDKLMDKDNNTYKQIQDanqeLFDNLTEWTGEDINV
.  | ..| ..  . ..      . .. .. || ...
llrkrlekeadkqlLlrg....kvldvmksvgetlkg
subfamily_MINPP1_pd Subfamily MINPP1 60-172 2.9e-09 28.3 In-house 90-198 (420) alignment 
Range on Protein: 60-172
Range on HMM: 90-198/420.0
GQLSIKGMREEYHLGTVFKSRYLDTgFMdSGYNRSQIYVRSTDYDRTLMSAQCVLAGMypPGENQMFdpDLEWQPIPVHTTPQKYDSLLN-VASCPVYDK
..|  .|  | ..|.  ...|...  |    ||. .....||.  ||. |||  . |.   ......  . | ... . .  |. | ||  ..||. |..
kslvaqgqeeleelakrlarrfpal.fe.evynpdsfsfastakkRtvksaqaFaeGL..setgevl..gdefnivlqeiseqesdklLrffdsCkkykn

LMDKDNNTYKQI-QD
 ..|.. . |.  . 
kvkknelnlkeeeef
subfamily_PXYLP1_pd Subfamily PXYLP1 251-348 2.3e-12 37.8 In-house 298-396 (419) alignment 
Range on Protein: 251-348
Range on HMM: 298-396/419.0
NRVLKDMQNKATGVmPDMKMVLYSAHDTTVATMLSVFDMFDGKQPPYSAAFAVELYSSGSSkNDFFVRFYY--HNETDSNDFVELTHPNCSKD-CPLEKL
. ... |.    ||    |.||||.|| |.  ... ... ... . |..  . ||| . .| .....|  |   . |.  || |  . . .|| |||| |
rdivsrmlkiieGv.dkekfvlysghDvtlrplvaaLglseartiayasrlvfelyrreas.keyylrvlynGkDvtqkvdfCegdskrskkdlCPlenl

K
 
v
subfamily_HP2-Group1_pd Subfamily HP2-Group1 253-342 5e-12 36.8 In-house 309-399 (422) alignment 
Range on Protein: 253-342
Range on HMM: 309-399/422.0
VLKDMQNKATGVMpDMKMVLYSAHDTTVATMLSVFDMFDGKQPPYSAAFAVELYSSGSSKN----DFFVRFYYHNETDSNDFVELTHpnCSKDC
. |....  ||     |..||| ||||.  .|| ... ..| |||.. . .||..  .. .    .. ||  |  .     | .  .  || . 
iwkevnesltGed.lrkfllysGhdttliqllsalnvdefkwppyasllllellevstapaastpqyavrvlynGklkklpfcdane..csyeq
gpUL132 Glycoprotein UL132 357-422 1.1e-07 17.7 Pfam-A 21-86 (235) alignment 
Range on Protein: 357-422
Range on HMM: 21-86/235.0
TEKEWSSSCSTTTAPTSSPTLAPSNDIEMWLVIALCITSGILILLILILLAFMTKVCCCGRKKRMY
| .| | |   ||| ..| . .|.. .|  | | . | ||  || .|..|  .  . |. ...|..
tssetsvstnvttaleastqkepndvvekvlaivvyivsgvsilsllvvlvavlysschkkpgrkf
GP41 Retroviral envelope protein 367-428 1.8e-06 14.0 Pfam-A 134-193 (204) alignment 
Range on Protein: 367-428
Range on HMM: 134-193/204.0
TTTAPTSSPTLAPSNDIEMWLviaLCITSGILILLILILLAFMTKVC-CCGRKKRMYVALNNQ
.. .. |   || ..|.  |.     |  |||||||.|.| .. ||  .| |.. .|  |. .
elqkldswaqlanwfdwtsWi...kiikigililliiivlrilvkvlrnckrvrqgysplqme
Tweety Tweety 377-419 5.7e-06 11.2 Pfam-A 8-51 (406) alignment 
Range on Protein: 377-419
Range on HMM: 8-51/406.0
LAPSNDIEM-WLVIALCITSGILILLILILLAFMTKVCCCGRKK
..|.....   |..  ...  .|.| .|.|| ..  .||. ||.
frpedesyqqsllllasvaaallalsLllllvYlltlCCdrrke