Gene cnep-1 in Caenorhabditis elegans

Synonym: CELE_F45E12.1, scpl-2

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily DULLARD
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP047_AA protein Get Run
CeleP047_AA_85-238 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
DUF705 Protein of unknown function (DUF705) 75-110 5.2e-06 11.9 Pfam-A 110-145 (297) alignment 
Range on Protein: 75-110
Range on HMM: 110-145/297.0
SPLTTHRLLTVKRKILVLDLDETLIHSHHDGVLRQT
| |....|.   . ..|.|||.|||  ...  .|. 
sqlkeeslvleiphviVfDlDsTLitdeeevriRde
CPDc_SM00577 86-238 1.4e-45 146.9 In-house 1-146 (146) alignment 
Range on Protein: 86-238
Range on HMM: 1-146/146.0
KRKILVLDLDETLIHShHDGVLRQTVKPGTPSDFTIRvvidrhpVKFSVHERPHVDYFLSVVSQWYELVVFTASMEVYGTSVADRLDRGRGILKRRYFRQ
|.|.|||||||||.|| ..   ...... .|.|....       ... |..||.||.||. .....|||.||.... | . ..|.||. | . .|...||
kkkvLVlDLdetLvhs.anmaepksfsevsptdslae.......tlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkrllkyrvlyRq

HCTMEVGGYTKD-LSAIHPDLSSICILDNSPGAYRKFPHNAIPIPSWFSDPNDT
.|... |...|| || .. |||...|.|||. ...  |.||..|....|...||
dcrlvkgkllkddlsllkvdlskvviiDnseestlvnpenalkikpyisalsdt
subfamily_DULLARD_pd Subfamily DULLARD 87-238 3.1e-79 256.0 In-house 1-152 (153) alignment 
Range on Protein: 87-238
Range on HMM: 1-152/153.0
RKILVLDLDETLIHSHHDGVLRQTVKPGTPSDFTIRVVIDRHPVKFSVHERPHVDYFLSVVSQWYELVVFTASMEVYGTSVADRLDRGRGILKRRYFRQH
||.||||||||||||.||.| ..||||||..||...|.||..||.|.|..|||||.||.|||.||.||.||||||.|...|.|.||.|||||||||.|||
rktlvlDlDetlihsahdsvtkstvkpgtapdfvvkvlidkepvlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqh

CTMEVGGYTKDLSAIHPDLSSICILDNSPGAYRKFPHNAIPIPSWFSDPNDT
|..|.| ||||||....||||..|||||| ||||.|.||||| ||.|||.||
CvlesgkytkdlslvssdlssviilDnspvayrknpdnaipikswlsdpsdt
NIF NLI interacting factor-like phosphatase 88-257 4.6e-50 161.6 Pfam-A 1-159 (159) alignment 
Range on Protein: 88-257
Range on HMM: 1-159/159.0
KILVLDLDETLIHSHHDGVLrqtvkpgtPS----DftirvviDrHPVKFSVHERPHVDYFLSVVSQWYELVVFTASMEVYGTSVADRLDRGRGILKRRYF
|.|||||||||.|| ..  |        ..    .       . .  |.||. ||..|.||  .|..||.|.||||.. |   | |.||. . ..|.|..
ktLVLDLDetLvhskekkdl........kedgkkv.......e.ektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklfkkrly

RQHCTMEVGGYTKDLSAIHPDLSSICILDNSPGAYRKFPHNAIPIPSWFSD-PNDTCLLNLLPFLDALRFTSDVR
|..||.. | |.|||| .. |||.. |.|.|| .... |.|.|||.....| ..||.||.|||||.||.. .|||
resctlrngkyvKdLsllgrdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpflealeksddvr
subfamily_SCP_pd Subfamily SCP 88-238 1.9e-41 133.1 In-house 1-142 (142) alignment 
Range on Protein: 88-238
Range on HMM: 1-142/142.0
KILVLDLDETLIHShhdgvlrqTVKPGTPSDFTIRVVIDRHPVKFSVHERPHVDYFLSVVSQWYELVVFTASMEVYGTSVADRLDRGrGILKRRYFRQHC
|.||.||||||.||        . || . .|| . | ||    .  |  ||||| ||  |.. .|.|.||||.  |.  ||| ||.  ..|. | ||..|
kclvidldetlvhs........sfkpvknadfvvpveidgtvhqvyvlkrphvdeflkrvgelfevvlftaslakyadpvadlldkk.kvlrarlfresc

TMEVGGYTKDLSAIHPDLSSICILDNSPGAYRKFPHNAIPIPSWFSDPNDT
..  | | |||| .  ||... |.|||| .|   |.||.|. |||.|..||
vfhkgnyvkdlsrlgrdlkkviivdnspasyifhpenavpveswfddkedt
subfamily_FCP1_pd Subfamily FCP1 89-228 2.8e-18 58.4 In-house 3-139 (146) alignment 
Range on Protein: 89-228
Range on HMM: 3-139/146.0
ILVLDLDETLIHSHHDGVLrQTVK--PGTPSDFTIrvviDRHPVKFSVHERPHVDYFLSVVSQWYELVVFTASMEVYGTSVADRLDRGRGILKRRYFRQH
.||.|||.||||. .|  . .. .      . ||.     ...  . |. ||..  ||. .|. ||| ..| .   | ...|  ||  . . ..| . . 
vLvvDlDqtlihttkdpti.evkeekkkdikkftl....peekevyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrd

CTMEVGGYTKDLSAIHPD-LSSICILDNSPGAYrKFPHNAIPI
 ...    ||.|... |   | ..|.|.    . .| .| | .
elldassktkklkklfptddsmvviiDDredvW.nfaenlikv
subfamily_CTDSPL2_pd Subfamily CTDSPL2 90-238 6.4e-35 112.2 In-house 2-142 (142) alignment 
Range on Protein: 90-238
Range on HMM: 2-142/142.0
LVLDLDETLIHSHhdgvlrqtVKPGTPSDFTIRVVIDRHPVKFSVHERPHVDYFLSVVSQWYELVVFTASMEVYGTSVADRLDRGRGILKRRYFRQHCTM
|||||||||.|.         ...   . .| .|. . .  .  |. ||..  ||. ||. .|...|||| .||   . | ||  .  .| | ||.|| .
lvldldetlvhcs........lekleeatltfpvlfenktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlfrehcvc

EVGGYTKDLSAIHPDLSSICILDNSPGAYRKFPHNAIPIPSWFSDPNDT
  | | |||| .  ||. . |.|||| |.    .| ||| |||.| ||.
vdgnyikdlsilGrdlektiivdnspqafayqlenGipieswfedendk
subfamily_TIM50_pd Subfamily TIM50 133-237 5e-21 67.2 In-house 22-125 (126) alignment 
Range on Protein: 133-237
Range on HMM: 22-125/126.0
SVHERPHVDYFLSVVSQWYELVVFTASMEVYGTSVADRLDRgRGILKRRYFRQHCTMEVGGYTKDLSAIHPDLSSICILDNSPGAYRKFPHNAIPIPSWF
 .. || ||.||. ... .|.||||..  .. . . |.||  ..... | ||....   |  .|||| .  ||| . ..|  . .... |.||. .  | 
rfkkrPgvdafleqlaelfeivvftseqgltaaplidkldP.kqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvdldkksvklqpenalalkkwe

SDPND
 . .|
Gnadd