Gene F18E2.1 in Caenorhabditis elegans

Synonym: CELE_F18E2.1, F18E2.1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP060_AA protein Get Run
CeleP060_AA_119-323 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Metallophos Calcineurin-like phosphoesterase 117-323 1.7e-22 73.7 Pfam-A 2-200 (200) alignment 
Range on Protein: 117-323
Range on HMM: 2-200/200.0
KVCVFGDLGYWHGNS---TESIIKHGLAGDFDFIVHLGDIAYDLHTNNGQVGDSYlNVFEPLISKVPYMVIAGNHEDDYQNFTNYQKRFSVPDNGHNDNQ
.. |.|||....  .   .. ..|..  ...|....|||. .     ... .. . .  ..|  ..|.... ||||.|. |. ....    .|.  ..| 
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalld.ylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglang

FYSFDLGPvhWVGVSTETYGYYYEYGMDPVMTQYDWLKRDLTTANSNRAAHPWIFTFQHRPFYCSNVNSAECqsfenrlvRTGWLDMPGLEPLFLQTSVD
.....  .  .  . |.  .|.       . . . .   .   |...||  ....   |.|...|  ..           .  .   . ||.|...  ||
eeeyenlk..itllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi........gselfgpdalekllekygvd

FGFWGHEHSY
  ..||.| .
lvlrGHtHkp
Metallophos_2 Calcineurin-like phosphoesterase superfamily domain 117-325 5.6e-07 21.7 Pfam-A 2-123 (156) alignment 
Range on Protein: 117-325
Range on HMM: 2-123/156.0
KVCVFGDLGYWHGNsTESIIKHGlaGDFDFIVHLGDIAYdlHtnngqvgdsylNVFEPLISKVPYMVIAGNHEDDYqnFTNYQ---Krfsvpdnghndnq
|.....|| .   . .| ....    . |.|.|.||.    .           . . .|....|  .. |||...   . . .   .             
kiaiiSDlHgnlda.leavledi..kevdlilhaGDlve..p...........eevvelledipvlavrGnhDeae..lpkelavel.............

fysfdlgpvhwvgvstetygyyyeygmdpvmtqydwlkrdlTTANSNRAAHPWIFTFQHRPFYCsnvnsaecqsfenrlvrtgWLDMP-GLEPLFLQTSV
                                         . |. .. .. . . . |. ..                    . ...  |. |. .  .
.........................................llaaaaleiegdrvllvhgtpls...................vqsseeelaellkeaga

DFGFWGHEHSYER
|. | || | .. 
dlvflGHtHkpkv
subfamily_ACP5_pd Subfamily ACP5 120-324 6e-69 223.8 In-house 1-189 (189) alignment 
Range on Protein: 120-324
Range on HMM: 1-189/189.0
VFGDLGYWHGNSTESIIKHGLAGDFDFIVHLGDIAYDLHTNNGQVGDSYLNVFEPLISKVPYMVIAGNHEDDYqNFTNYQKRFSVPdnghNDNQFYSFDL
||||||. ...|.... |.  |...|.|.|.||.||.|...|..|.|...|..|||.|||||||..|||| |. ||..|.|||| |    ..|..||||.
vfgDlgvseaaslatllkeeeaneldliihvGDlaYalkakneavwdefmnlieplaskvPymvsiGnhesds.nfsaykkrfsmp....sknewYsfdy

GPVHWVGVSTETYgYYYEygmdpvMTQYDWLKRDLTTANsNRAAHPWIFTFQHRPFYCSNVNSAECqSFENRLVRTGwlDMPGLEPLFLQTSVDFGFWGH
||||....|||.. .. .       .||.||..||..|| ||...|||....|||.|||| .. .| . |. |||.|   ...||.|. . .||. ..||
gpvhfislstevd.fslg......seqykWLekdLkean.nrkktpwiivmgHrPmYcsnkdeddc.tkeetlvrkg..lresledllykykvdlalsgH

EHSYE
|||||
eHsYe
PAPL 120-323 3.8e-53 172.5 In-house 2-194 (194) alignment 
Range on Protein: 120-323
Range on HMM: 2-194/194.0
VFGDLGYWHGNSTESIIKHGLAGDFDFIVHLGDIAYDLHTNNGQVGDSYLNVFEPLISKVPYMVIAGNHEDDYqNFTNYQKRFSVPdnGHNDNQFYSFDL
||||||. . .|.... |.   |..|.|.|.||.||.....|...|| ...  |||...|||||..||||..| ||.||..||| |  | ......|...
vfGDlGqtnasslkrlqketqkgkydailhvGDlaYaddeqnewdgdefmrqieplaasvpymvapGNHEeey.nfsnykarfsmp..gseegesnsses

GPVHWVGVSTETYGYYYEYGMDPVMTQYDWLKRDLTTANSNRAAHPWIFTFQHRPFYCSNVNSAECQSFENRlvrtgwldMPGLEPLFLQTSVDFGFWGH
|. ..   .. .. .....  |   ..  . . ..  |. ||...|||... |||.|||| .. .|.. ..         . .||.|... .||  ..||
gsnsysfetesvhfivlsseedvkekseqyewleedlakvnRsktPWiivmgHrpmYcsnkdkddckekakm........laaledllykygVDlvlaGH

EHSY
||||
eHsY
ACP5 120-321 5.1e-09 28.1 In-house 3-197 (198) alignment 
Range on Protein: 120-321
Range on HMM: 3-197/198.0
VFGDLGYWHGNS----TESIIKHGLAGDFDFIVHLGDIAYDLHT---NNGQVGDSYLNVFEPLISKVPYMVIAGNHeDDYQNFTNYQKRFSVPDNGHNDN
|.|| |    ..     ... | .   | ||.. |||  ||  .   .  .. .|. ....    .||..|..||| | ..| .  ..  .  .. .  .
vvGDwGrkgeynqsavakqmgkvaekldidfvlslGDnfyddGvtsvddprfkesfekiytakslqvpWyvvlGNH.Dyrgnvsaqieyakrskdsrfps

QFYSFDLGP-VHWVGVSTETYGYYYEYGMDPVMTQYDWLkRDLTTANSNRAAhPWIFTFQHRPFYCSNVNSAEcQSFENRlvrtgwldmpgLEPLFLQTS
..||..    |  .  ....  .  .....  ... ..|  .|..|...  |  |.. . | | |    .  . ..  .|           |.||. .  
lryslskkevvtelftekkdeksdqrevaerekyaeeql.kwlekalaksta.dwkiVvGHhpvySigehgdt.kelver...........llpllkkyk

VDFGFWGHEH
||. . ||.|
vdaYlnGHdH
subfamily_PAPL_pd Subfamily PAPL 143-321 9.8e-06 16.9 In-house 34-210 (212) alignment 
Range on Protein: 143-321
Range on HMM: 34-210/212.0
DFDFIVHLGDIAYDL---HTNNGQVGDSYLNVFEPLISKVPYMVIAGNHE-----DDYQNFTNYQKRFSVPDNGHNDNQFYSFDLGPVHWVGVSTETYGY
. .|...|||. |.      .. .  ... .||.    .||..|.||||.     .   ....  ||...|.  .. .  ..     |. | . |    .
eaqfvlalGDnfYekGvkdvddarfketfedvftaeslqvpwyvvagnHDykGnvsaqiaYsklskrWkfpslyytksfkipdsnatvqlvlidtvllcg

Y-------YEYGMDPVMTQYDWLKRDLTTANSNraahpWIFTFQHRPFYCSNVNsAECQSFENRlvrtgwldmpgLEPLFLQTSVDFGFWGHEH
            ..   .|. ||...|.... .     ..... | | .    .    ..  .|           |.||  . .|.  . ||.|
ksddlklegpvdvslaeeqwawleeeLkasead.....ylivaGhypvwsvaeh.GptkiLvkr...........LkPlLekynvtaylsGhDh
Metallophos_C Iron/zinc purple acid phosphatase-like protein C 345-409 2.3e-21 67.3 Pfam-A 1-62 (62) alignment 
Range on Protein: 345-409
Range on HMM: 1-62/62.0
KAPVYLISGSAGCHTPDalFTDKPWPWSAARNNDYGWSIVTVANRTHIRVEQISiDKNEQTVDDF
||||....|.||... .  |.... .||| |..|||.|..||.||||...|... ... | .|.|
kApvhIvvGaAGnglsk..fskpqpewsafresdyGysrltvvNrthLhwefvr.sddgqvlDsf